Conserved Protein Domain Family
PIH1_CS

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pfam18201: PIH1_CS 
PIH1 CS-like domain
This domain is found in yeast PIH1 and its homologs. This domain consists of a seven-stranded beta sandwich with the topology of a CS domain, a structural motif also found in Hsp90 co-chaperones such as p23/Sba1 and Sgt1.
Statistics
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PSSM-Id: 408028
Aligned: 15 rows
Threshold Bit Score: 102.103
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q292G3       254 FAVPKYsikqshdvdlseytdeldaklHVTVPRSLVVEIELPLLRSTAECQLDVTAKSVYL------------------- 314 Drosophila pseu...
CBZ13064     314 TSNPYF---------------------KENVPSYFAITLYLPGVQTIREVDVRIGYRRVDCyyidevadgeerdeeaaas 372
Q38DW7       296 TINPYF---------------------RETVPAAYLVELHIPTVTTIAEVDVRVSPKRIELlyvd--------------- 339 Trypanosoma brucei
Q4DT93       310 VLNPYF---------------------RENIPATYAVEVCIPTVTSIAEVEVRITPRSIEIsyvd--------------- 353 Trypanosoma cruzi
Q17BY1       275 FREP-----------------------ASGRVKTLIGEFYLPECTSAKEITLDIGEDRILL------------------- 312 yellow fever mo...
A0DMA1       283 VSRPKYrfiysypvey-sdfldsranmSIKLPNQLACDLKMQKVEAMKEIQLDLSNQGLVL------------------- 342 Paramecium tetr...
XP_001629864 259 PRNPEYtilhrgiidf-qnftnardscTSTRPKELVIRIDLPDL-ALNHCKYRYSAFSRCC------------------- 317
CAG10513     252 PAKPKYtvryrsyvdi-qdfrrsrnsaQSPRPKEIVVTIDVPLLKEVTGARVEARERMLLL------------------- 311
Q499A3       294 PTAPQYrlkyrsvldl-qdyrccrdsgSAGRPTAIIIEVEVPRLRSAQEAELRVEERRLLL------------------- 353 zebrafish
Q0P4V4       255 AATPNYtvrhrsyvdl-qdfrdsrdstPSPVPKELVITVDLPLLNSAAGVNLHIAGKNLSL------------------- 314 tropical clawed...
Q292G3       315 ----------LSERlgAKYRLK---LDLPFVVDDKAGNARFDTEKRRLSITLPVV 356 Drosophila pseudoobscura pseudoobscura
CBZ13064     373 aeggergaaaANKGsgASPFLS---LTLDYPVSDDVVEAKYVRKTSLLKLKLAVQ 424
Q38DW7       340 -------------cedGVPFLT---VPLGYPIDEELQDAKFVRKTRTLKLKLRVK 378 Trypanosoma brucei
Q4DT93       354 -------------aedGAPFLS---IPLDYPIDEDAPNAKFVRKTHMLKMQLLVK 392 Trypanosoma cruzi
Q17BY1       313 ----------EARK--KGYLLD---AFVDYQIDGSRISAQFNTKTKMLNVIMPVI 352 yellow fever mosquito
A0DMA1       343 ----------DVPN---KYFLD---IKLPYPIEQTEASAKFDAKSKTLKIRAPIS 381 Paramecium tetraurelia
XP_001629864 318 -----------------QFFLDichITLPYPIDENKGSAKFDKSKQQLVVTLLVL 355
CAG10513     312 ----------ESES--PAYRLE---LPLAYPVDEEKGEAKFSKQKGQLTVTLPVL 351
Q499A3       354 ----------EAPT--AEYRLE---LPLAYPVEEERAEAQFNHTHRLLTVTLPVL 393 zebrafish
Q0P4V4       315 ----------ESEK--PAYKLN---VKLPYAVEDNQGKAQFNKVKKQLIITVPVI 354 tropical clawed frog
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