1GSO,5VEV,2YW2,2YRW,2XD4,2IP4


Conserved Protein Domain Family
PurD

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COG0151: PurD 
Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]
Phosphoribosylamine-glycine ligase is part of the Pathway/BioSystem: Purine biosynthesis
Statistics
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PSSM-Id: 439921
Aligned: 828 rows
Threshold Bit Score: 254.552
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GSO_A         3 MKVLVIGNGGREHALAWKAAQSPL-VETVFV--APGNAGTALEPalQN----VAI-GVTDIPAL--LDFAQNEKIDLTIV 72 
WP_012997331   2 NKVLLMGSGGREHAIAKALKDGG---AKIYAvmKHKNPGIARLS--ED----YIIgDDSSVSFVknLDWVKFKKVDFAVI 72 
WP_096685656   4 NKFLVVGNGARESAFAINLSSD----SIVYAviQHKNPTIVECV--QNthgkYLVaDVNDPDVV--LNFARDNEIDYVFV 75 
WP_011405648   1 MKILMVGSGAREHAIAKALNKT----ADVYTymGRKNPGLARIS--KN----YTVnDESNFNEI--IKFAQENNVELAFI 68 
WP_013413133   1 MKVLVVGGGAREHVICESLHGE----AEIYSvmSNLNPGIARIS--E-----YKImDENNVEKI--RDFALKNNIDIAVI 67 
WP_048061056   1 MKILVVGTGAREHAICSALADE----ATIYSvmGNRNPGISRLA--GN-----SLlLLKLTPKV--VRFASEKGVDMAFI 67 
WP_011170336   1 MKVLLIGGGAREHAIAMALKKNE--LVELYTlmKNKNPGIYALS--EE----VSFnSETDVPAI--KEFAEKIKPEIAVI 70 
WP_048812532   1 MKVLVVGTGAREHAICDALKDD----VDLYAymSKNNPGISKIS--T-----FKKgDEGEVDEV--AKFAKENEIELAVI 67 
WP_013798205   1 MKILLIGGGARESAIAHALKKNA--DVKLYTlmNNKNPGIARLS--EK----ISLnKETDLDAV--KAFAEEVKPDMAVI 70 
AAM02284       2 LKVLLVGSGAREHAIAEALCGAPDeDVELYAfmGNRNPGIIRLA--ED----YVVgDPTDVEAV--ARAAADWNVDFAVV 73 
1GSO_A        73 GPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLEGSKAFTKDFLARHKIP-TAEYQNFTEVE-PALAYLR---EK---GAPI 144
WP_012997331  73 GPEAPLINGMADMLEEKGIPVVGPRKDAAIIEGSKEFMRDLMKKHNIDgMVDYYVFNDPQ-KVEEFLK---NY---DKPF 145
WP_096685656  76 SSDQPLANGVVDVLLENNIRAIGGTKEATRIEWDKIYSIDLVKKVCGEcVPFYLVVSNDK-ELVDAVEefkKR---RLDI 151
WP_011405648  69 GPEAPLEMGIVDELEKEGIHSVGPTKSAAQIETNKAFMRKLFEDYDIPgSIKYGTFYDLD-EAYEFID---NF---DEPV 141
WP_013413133  68 GPESPLEKGIVDELMKAGIDCVGPTKDAAKIETNKFFMRKLFDKYDIEgSVFYRVFDNYE-EVCEFLD---NF---DKDV 140
WP_048061056  68 GPEAHLEAGLVDALEEAGIPSVGPTRDAARIETDKSFMRKLFEDYRIPgSITYRVFSDPE-ELREFME---DF---DSEA 140
WP_011170336  71 GPESPLGVGASDLLEEMGIPTVGPKKLPAQIETSKEFMRNLFKKYEIDgSLKYAAFNDYGtELEGFID---EMtslGKDV 147
WP_048812532  68 GPEAPLGKGIVNALEAVGVPCVGPAQESARIETDKSFMRNLFEKYQIKgSLTYKVFDNYE-DISAFLD---TY---EKDV 140
WP_013798205  71 GPEAPLGAGVADLLWDMGIPTVGPKKLPAQIETSKEFMRNLFKKYNIKgSLQYKAFEEYGeELEAFID---EMtnqGKDV 147
AAM02284      74 GPEDPLAEGVADRLEEEGIPTFGPKRGPARIEWDKGFARELMEKYDIPgRPEFGIFEDPD-EACDFID---EL---GKPV 146
1GSO_A       145 VIKADGLAAGKGVIVAM----TLEEAEAAVHDMLAgnafgdAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV 220
WP_012997331 146 VIKPVGVTGGKGVWVMGdhfkTKEDGIRYAKEIIEkk--igGVDRVIIEEKLVGEEFTLQIFTDGINLAGMPLVQDFKRA 223
WP_096685656 152 VVKPQGLTGGKGVKLMPnhlkKYEDCIDYSRILLKn----nPTERVLLVEKLDGIEFTIMGFTDGENLVLSPASYDYPYR 227
WP_011405648 142 VVKPIGLTGGKGVKIVGdqlaDNDEAKEYVKEIFHqk--mgGFEGVVIEELLLGEEYTIQAFVDGTHLIPMPAAQDHPHA 219
WP_013413133 141 AVKPVGLTGGKGVKVVGehlkDNEEAKQYAKQVIEnk--igGYSKVIIEERLLGEEFTLQAFCDGKKLVPMPAVQDHPHA 218
WP_048061056 141 VVKPVGLTGGKGVKIVGehlrDNMEALKYATEVIEkr--igGHPSVVIEERVVGEEFTVQAFSDGEHIVPMPAVQDHPHA 218
WP_011170336 148 VVKPAGLTGGKGVKVVGeqlkDNEEAKIYAKEVFDks--igG-GKIIIEEKLVGVEFTLHGFVDGENIVFMPAVQDHPHA 224
WP_048812532 141 VVKPVGLTGGKGVKIVGdhlkDNQDAKAYAKEVMDna--mgGFAQVIIEEKVVGEEFTIQAFCDGENLAAMPAAQDHPHA 218
WP_013798205 148 VVKPVGLTGGKGVKVVGeqlkDNEEAKQYAKEVFEkn--igG-GKVIIEERLIGVEFTLHGFVDGDTIKFTPAVQDHPHA 224
AAM02284     147 AVKPAGLTGGKGVKVVGdqlkNLDEAKEYVKEIFEed--igGIPKVIIEEKCVGEEYTIQAYTDGEKVIPTPAVQDHPHA 224
1GSO_A       221 GDKDTGPNTGGMGAYSP----APVVTDDVHQRTMeRIIWPTVKGMAAE-GNTYTGFLYAGLMIDKQGnPKVIEFNCRFGD 295
WP_012997331 224 YEGDLGPNTGGMGSYSMenhlLPFLTKEDYTKAM-KIMEDIIAAMRRE-GRIYKGIIYGQFMLTAEG-PKIIEVNCRFGD 300
WP_096685656 228 HENDLGDGTGGMGCFTNselkLPFMSDSDLDQCK-EIMKKTLSEMRER-NLNFNGILNGGFFKTKDG-IKFMEYNGRFGD 304
WP_011405648 220 FVGNKGPITGGMGSYSDknhlLPFLTQEDYDKSV-EIMEKTIKAIAKE-QEPYKGILYGQFMLCKDG-PKVIEYNARFGD 296
WP_013413133 219 FEGDTGPITGGMGSYSDkdglLPFLRRDEYNKAV-KIMKNTLKAINKE-VGPYKGILYGQFMLCADG-PKIVEYNARFGD 295
WP_048061056 219 YEGDQGPITGGMGSYSDsdglLPFLTQKDYEDAV-EIMQRTVDAIRKE-TGPYRGILYGQFMLSADG-PKLIEYNARFGD 295
WP_011170336 225 YNNDEGPITGGMGSYSCpnhgLPFLSEEMLDKAE-KIMEKTVNSINLE-VGPYKGFLYGQFMLTADG-PKIIEYNARFGD 301
WP_048812532 219 FENDQGLITGGMGSYSDvgglLPFLTQEDYDEAV-DIMKETLKAIAKE-TTPYKGILYGQFMLSKDG-PKLIEYNARFGD 295
WP_013798205 225 YENDEGPITGGMGSYSCpdlsLPFLTENDLKDAK-EIMEDTVKALKKE-VGDYQGFLYGQFMLTADG-PKIIEYNARFGD 301
AAM02284     225 YEGDKGPITGGMGSYSCpdglLPFITKEDYERSV-EILERTVEAIKKEtGEPYRGVLYGQFMLTAEG-PVVIEFNCRYGD 302
1GSO_A       296 LETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGVVMAAGGYPGDYRT-GDVIHGlPLE-EVAGGKVFHAGTK- 372
WP_012997331 301 PEAMNVLSILKTNFVDIAWSIIEGKLKP--VEFENKATVVKYVVPEGYGTKPLA-NQEIKVnEERiKREGALLYYASVN- 376
WP_096685656 305 PEAMNVLSVLNEPLSTVLENIWHKKISEDNITFVGKASVVKYLVAKEYPQKSES-ETLFSIkKEEmSKFGISIFCSFCE- 382
WP_011405648 297 PESMNVLSVIDDDLAKISKQIVDGTLDS--VNFLNKSSVCKYVVPDKYPNTHVA-DTVVDVdEDKiNELGAQVFYAAVY- 372
WP_013413133 296 PEAMNVLPLLKDSFLEICERIVDGNLKK--ADFRKKATVCKYIVPEGYPKTKFA-GHPIKInEKEiSKLGVKLYYASVT- 371
WP_048061056 296 PEAMNVLPLLESSMLEICEGIVDGNLKS--ASFMNLATVCKYLVPEGYPESGVA-GAEIKVdEKKiEDMGVITYYAAVN- 371
WP_011170336 302 PEAMNLLPILKTDFLDVCFAIAEGKLDKINIEFENKATVCKYVVPNGYPIDPVR-NKELAVdEKAiEDANAILFYASIN- 379
WP_048812532 296 PEAMNVLPLLKTPMVDVCKAIVDGKLED--VEFEDKASVCKYIVPDGYPDTPHA-GELIEIdEEAiEALGAKVFYAAVS- 371
WP_013798205 302 PEAMNILAILKNDFVEVCEAIANKKLKDIDVKFENKATVCKYVVPNGYPTNPVR-NKEIFVdEEKiKETGAILHYASVN- 379
AAM02284     303 PEAMNILPIAEGDIVTLHASIAEGSMEG-EIEFLEKATVCKYVVPEGYPESSEGeGDVIEVdEECiHRYDAVPYYASVNl 381
1GSO_A       373 L-A-DDeQVVT-----NGGRVLCVTALGHTVAEAQKRAYALMTD-IHWDDCFCRKDIGWRAI--ER 428
WP_012997331 377 E-S-NG-KIYT-----TTSRSLAVVGIAENLYEAEEIAEKALRH-IVGR-VYSRHDIAKKEMidAK 432
WP_096685656 383 ElG-NR-GAYTeyktlKTSRVIAFGCISEDIESASDLINEAIEKyVMRQGLEFRRDIGSRENliLL 446
WP_011405648 373 Q-DmDD-SIKL-----TSSRALGVLAVKDSIKEAEKICEEAIKY-VKGE-VYHRNDVATEELlnEK 429
WP_013413133 372 Q-K-NN-KIYM-----TSSRSLGLVAEGDSIYKAERLCEKATNY-VEGK-VYHRRDIGTRELieKR 427
WP_048061056 372 Q-E-DD-HIYT-----SSSRALALVAPADDIYSAEELCEEATAH-VKGR-LYHRRDIGTRELveKR 427
WP_011170336 380 E-E-NG-KLYI-----TGSRSAAVVGISENIEEAEKIAQKAIEN-FKGE-VYYRSDIGTLDLikKR 435
WP_048812532 372 Q-E-DD-GVHL-----SGSRALGIVAQGDTIAEAEKIAEEACGL-VEGN-VYHRRDVGTEALiqKR 427
WP_013798205 380 E-V-DG-KLYM-----TGSRSVAVVGVADTIEEAEKIAESAIQY-IKGD-VFHRSDVGKLDLikKR 435
AAM02284     382 D-E-DG-KIRM-----TSSRALAIVGIGDELEQAEEAAESAIREcVSGERIRHRSDIGKHETveKR 439
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