Conserved Protein Domain Family
DUF778

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pfam05608: DUF778 
Protein of unknown function (DUF778)
This family consists of several eukaryotic proteins of unknown function.
Statistics
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PSSM-Id: 428540
Aligned: 26 rows
Threshold Bit Score: 113.524
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001567664 338 APFVSWLFPLAGHVAISNAEGSrLFTFESSYYVREE----------------KLvsvldcvlreevleprttsllreasp 401
Q9SD42        38 LPFISWLVPFIGHVGICREDGV-ILDFAGPNFVCVD----------------NF-------------------------- 74  thale cress
Q1HTV3        39 LPVLSWFIPFIGHIGICREDGV-ILDFAGPNFVSVD----------------NF-------------------------- 75  tomato
Q4Q4Y7       156 APFVSWLFPLVGHVAISNAEGSqLYTFESSYYVREE----------------KLisvldrvlreegqeqhaasllreaph 219 Leishmania major
CBZ12152      35 IPVLSWILPFVGHTAVCDSQGR-IYDFQGAYRIGQD----------------RM-------------------------- 71 
CAM45375      40 IPILTWFLPFVGHIGVCDSQGR-IYDFQESYRIGQD----------------RM-------------------------- 76 
Q4CRJ7        37 IPVLSWIFPFIGHVGICDSAGR-IHDFEGPYHIGVD----------------KM-------------------------- 73  Trypanosoma cruzi
Q38B30        31 IPLVSWLFPFVGHVGICDSTGR-IFDFEGSYCIGVD----------------HM-------------------------- 67  Trypanosoma brucei
EGT58820      25 IPCLTWFFPFIGHMGIANSRGV-IRDFAGSFYVAVSpqnrgfssqfnvfsgrRH-------------------------- 77 
XP_003062652  18 IPLVTWLLPPVGHLGICYSSGL-VTDFLGPRFVHRG----------------SL-------------------------- 54 
XP_001567664 402 lgsrvelsqlpvtttsrsptssqqlgalvmsdasasdaaltspsdtsagallqcsatssvfssrcsarplrragrqrsAA 481
Q9SD42        75 ------------------------------------------------------------------------------AF 76  thale cress
Q1HTV3        76 ------------------------------------------------------------------------------TF 77  tomato
Q4Q4Y7       220 vgsrvdlsalptttslhsstgsqlpgmpmasdasasdtavtspsdasagsrlrcrptspvfpphcsarpprragrprsAA 299 Leishmania major
CBZ12152      72 ------------------------------------------------------------------------------LF 73 
CAM45375      77 ------------------------------------------------------------------------------LF 78 
Q4CRJ7        74 ------------------------------------------------------------------------------LF 75  Trypanosoma cruzi
Q38B30        68 ------------------------------------------------------------------------------LF 69  Trypanosoma brucei
EGT58820      78 ------------------------------------------------------------------------------GF 79 
XP_003062652  55 ------------------------------------------------------------------------------GF 56 
XP_001567664 482 GASASghahtqcvrIWDLKPllmesrgrrtrrtpscfttqg---------------------gkqaavvlwerlqgllqp 540
Q9SD42        77 GAVSR---------YIQINK------------------------------------------------------------ 87  thale cress
Q1HTV3        78 GAPTC---------YFQLSR------------------------------------------------------------ 88  tomato
Q4Q4Y7       300 GAPASghahtqcvrIWDLKPllmesrgrrtrrtpcglttqg---------------------gkqaaavlwerlqellqp 358 Leishmania major
CBZ12152      74 GNPVK---------YWDVSR------------------------------------------------------------ 84 
CAM45375      79 GNPVK---------YWDISR------------------------------------------------------------ 89 
Q4CRJ7        76 GNPVK---------YWNISR------------------------------------------------------------ 86  Trypanosoma cruzi
Q38B30        70 GNPVK---------YWDISA------------------------------------------------------------ 80  Trypanosoma brucei
EGT58820      80 GWPTR---------YWQTGSgahrraasrrsiepfkrlpmtqnspilaqnspdlaqnspdlaqnspiftqntpnfaqnss 150
XP_003062652  57 GAVCR---------YWRLDP------------------------------------------------------------ 67 
XP_001567664 541 seiSTSSAQGaATAGASTSTTSSLIRRTSNMkhRYtsgyhsDDAdgir------------------sapgMSSSSGEE-E 601
Q9SD42        88 ---EMESSRSsSSGMFNGERRYEQEEDSHEKepTW------DDA--------------------------LRKSTQEY-Q 131 thale cress
Q1HTV3        89 ---EQCCCLSpYSAEPTGEYVENHDESGGNVd-TW------ESA--------------------------IRKSIQEF-Q 131 tomato
Q4Q4Y7       359 tevSTASVQGaSPAGGAASKALSPTPPTLSVkrRYaseyhsDDAdgir------------------sapgMSSSGEE--E 418 Leishmania major
CBZ12152      85 ---DYIPSFY-NADQQNSAEREEAVKREVA---AY------DAA--------------------------LMSTISHFrQ 125
CAM45375      90 ---DCIPSFY-NPDPHNSQERWAAVHREVE---AY------DAA--------------------------VASATNHFrQ 130
Q4CRJ7        87 ---MYVPTFY-RSQGENPRTTEETCRREVE---EY------DAA--------------------------VERVTKHFrK 127 Trypanosoma cruzi
Q38B30        81 ---MYVPSSRfPPGGLLSGDVEERRRRETE---EY------DRA--------------------------LSGVTTRFrK 122 Trypanosoma brucei
EGT58820     151 nlaQNCPDPTeLSPKNEREIAEFSPKPTERAqnSL------DSAqnspnlarksssfvrispnlarkspdLAQSSPNFsQ 224
XP_003062652  68 ---SKVAERRrWKGGDGEGDGEGDDGIA-----AW------DDG--------------------------VRRAERFFnE 107
XP_001567664 602 G------------------------------------------------------------------------GEYELLD 609
Q9SD42       132 H------------------------------------------------------------------------HSYNILT 139 thale cress
Q1HTV3       132 H------------------------------------------------------------------------QSYSIFT 139 tomato
Q4Q4Y7       419 G------------------------------------------------------------------------EEYELLD 426 Leishmania major
CBZ12152     126 T------------------------------------------------------------------------EVYNFFT 133
CAM45375     131 A------------------------------------------------------------------------ETYNFFA 138
Q4CRJ7       128 T------------------------------------------------------------------------QLYNFFT 135 Trypanosoma cruzi
Q38B30       123 T------------------------------------------------------------------------QTYNFFT 130 Trypanosoma brucei
EGT58820     225 NtpdlaenppnlarkppnsaqnsfnsaqtplnsaqkatnlaqkppnlalkspdlarksfnltqnplnsaqkspNSHNLIC 304
XP_003062652 108 G------------------------------------------------------------------------EDYNIFG 115
XP_001567664 610 AETAQFYNRNLNatirlfrgsadgsinspdvvlqhhssfsfvgfvleacgvgsqgkpnstvsapkppvkdeasggnavtp 689
Q9SD42       140 CNCHSFVANNLN-------------------------------------------------------------------- 151 thale cress
Q1HTV3       140 CNCHSFVANGLN-------------------------------------------------------------------- 151 tomato
Q4Q4Y7       427 AETARFYNRNLNatirlfrgsadgsinspdvvlqhhssfsfvgfvleacgvgsqgkpssavsapkspakeaanggsaaas 506 Leishmania major
CBZ12152     134 NNCHSFVAASMN-------------------------------------------------------------------- 145
CAM45375     139 NNCHAFVAAALN-------------------------------------------------------------------- 150
Q4CRJ7       136 NNCHSYVACVLR-------------------------------------------------------------------- 147 Trypanosoma cruzi
Q38B30       131 NNCHSYVASVLE-------------------------------------------------------------------- 142 Trypanosoma brucei
EGT58820     305 DNCHSHVALALN-------------------------------------------------------------------- 316
XP_003062652 116 NNCHQYAAHALN-------------------------------------------------------------------- 127
XP_001567664 690 pkpsgdtngpatapasddavpgeSLSSEEEIHWGVMKLLFHVSVFGKW 737
Q9SD42       152 -----------------------RLSIK-SGGWNVVNLATLVLFKGRW 175 thale cress
Q1HTV3       152 -----------------------RLGFQ-SGGWNVVNLAIFIFLKGRW 175 tomato
Q4Q4Y7       507 asppaaanrpatasasddavpgeSLNSEGEIHWGVMKLLFHVSVFGKW 554 Leishmania major
CBZ12152     146 -----------------------EQQLK-KQHMGMVSIAIGMMTRGRY 169
CAM45375     151 -----------------------RSQFQ-KEHTGTASLAIGMMLQGRY 174
Q4CRJ7       148 -----------------------DHPLTAAGSFSVFRVAWGLLIHGRY 172 Trypanosoma cruzi
Q38B30       143 -----------------------EMTNGPRRPWNMFWIAWGLAIHGRS 167 Trypanosoma brucei
EGT58820     317 -----------------------KMRYQDREDWGMVNLAWYSLTKGSF 341
XP_003062652 128 -----------------------LMAYDGKKDWNTVHLAAAIVFRGKW 152
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