Conserved Protein Domain Family
cobS

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PRK00235: cobS 
cobalamin synthase; Reviewed
Statistics
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PSSM-Id: 234697
Aligned: 260 rows
Threshold Bit Score: 119.169
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
62391041   23 LFEGIFTALNWMTVLPVPgasvFDRTTGARVMASLPFVGFVFGMFTAIIMWAIGpisgviHVDGLLVAVLIVAFWELLNR 102
284161423   1 ---MFMDLISFFTRIPAE----GKLERVAKQLWALPLLALLTSALPMALLLLKI----------PIREILALIALYATIG 63 
14590281    1 ----mknILPFLTRIPIK----GDFEKARRELWAFPLVSVFTSPLPALILYLKV----------PLASILALLSLYFTIG 62 
18976671    1 ----mknLIQFMTRVPIK----GDFEKAREEVWMLPLLTPLTAFIPSLILYLNI----------PLKNVLSILSLYWVIG 62 
14520261    1 ----mrnILPFLTRIPVK----GDFEKARNELWAFPLVSLVSSIIPIAILYLRI----------PLANVLALLSLYFVIG 62 
240102595   1 ----mrnLLPFFTRIPVK----GDFERVRNELWALPLLAPLTSALATLVLYLEL----------PLSNVLAILALYFTTG 62 
57640792    1 ----mrnILPFLTRIPVK----GDFEKARNELWAFPLVALVSSALPTLILYLGL----------PLSNLLAVLALYWTIG 62 
212223833   1 ----mknLLPFLTRVPIK----GDFEKVREELWAFPLVALVSSALPTLVLYLKL----------PLSNVLAVLALYFTIG 62 
13541326    1 MISGLRSSFSFFTLVPSR------QKDIGNPITFLPLVVTVGALIGDSILYITW------QFSHLIASFLSISSIIIYNG 68 
16082105    1 -MKGLRSAFSFFTIIPIK------SELDEHLIAYVPLVALFDAALAASLYVAIYg------ISKLLASFISVSAIYIVNG 67 
62391041  103 FMHLDGLADVSDALGSYAAPPRAREILADPRTGLFGLATAMLSVLLQVAAVASLVDSTVWWMICFIPVLGRIAGQVTALK 182
284161423  64 LIHLDGLADFSDGLMAKGDVKVKFRAMKDVNVGIAGIFAVIVVILLQVGALRFA----PFYAIFLAELNSKFSILLSLSV 139
14590281   63 LLHLDGLADWADGIMVKGDREKKIKAMKDINVGVAGIFAVVTVLMLQIYSLQLV----PFYAIFLAELNSKFAMLLAMAT 138
18976671   63 LLHLDGLADWADGIMVKGDREKKVRAMKDVNTGIAGTFAVVMILLIQVYSLFSA----PFYSIYLAELNSKMAMLLALAT 138
14520261   63 LLHLDGLADWADGIMVKGDRERKIKAMKDLNTGIAGVFAVVVVLFLQVYSLSML----PFYAIYIAELNSKFSMLLGLAT 138
240102595  63 LLHLDGLADWADGVMVKGDRERKIKAMKDLNTGIAGVFAVVMVFLLQVYSLPLL----PFYALYLAELNSKFAMLLALAT 138
57640792   63 LLHLDGLADWADGIMAKGDRERKIEVMKDVNTGIAGLFAVVIVLLLQVYSLQLL----PFYALFLAELNSKYAMLLALAT 138
212223833  63 LLHLDGLADFADGVMVKGNRERKIKAMKDLNTGIAGLFAVVMVLFLQVYSLQLV----PFYAIFLAELNSKLAMLLALAT 138
13541326   69 LNHFDATADLGDALMVRD-KSRIPEVIKDHHVGAGGIFAVIFVYGIAVLSLARSTLYIGLVGILIGQVVSGSSMMISLIG 147
16082105   68 LNHVDAVADAGDAMMIRN-RSRIREVFEDHDVGAGGVFTLIFVYLLALISLSSMDLYIGIFSIILAEFLSKSMMMITLHR 146
62391041  183 NHNAFSptGFGALVIGTVKFWWIALWLLVTAALAFwcaelisplspltsvNTPFVAGpfpaainpawlggwvAITAVVAC 262
284161423 140 KKPLGE--GLAKFFMDRLDRRQFFVGFGIYIALIV---------------AVAFYDR---------------IALISALS 187
14590281  139 KKPLGK--GLGAYFMEALDRNQLLYGTLIYLLLYIp--------------VIIAEPR---------------NLVSFLGL 187
18976671  139 KKPLGE--GLGKYFMDKLTTKRVFLGGVLYALLLIp--------------ILLYDPQ---------------SIFALLGL 187
14520261  139 KKPLGQ--GLGAYFMEGMNGRQLAIGVVLYVLLYLp--------------VVIYDPS---------------ALFGVMGL 187
240102595 139 RKPLGQ--GLGAYFMEGMNGRQLTLGTALYLLLLLp--------------VAYIEPR---------------SISSLLGL 187
57640792  139 KRPLGK--GLGAYFMEGMNGRQLALGTLLYVLLGLs--------------VVLFEPR---------------ALAGILGL 187
212223833 139 RKPLGQ--GLGAYFMERMNSGQLLGGFIFYAILLVp--------------VVVYEQN---------------ALVSLLGL 187
13541326  148 SQPFVP--GLADYFISLFRKHSVGYTIEFLAIPIIvsfif----------------------------splyVVIVALNL 197
16082105  147 SRPLFQ--GIGSLFIDLYRKHDSLYTVEFVVIPIVl-------------aLLSRASI---------------MISVALAF 196
62391041  263 VFAALFSRRLS-RSFGGLNGDCIGACIHLGASISAVMFAVVAN 304
284161423 188 LIVGLLTIKIAlDNFKGLNGDCVGAVAEITRTSSLVLCAILDN 230
14590281  188 FIGLYAVKISL-DNFGGLNGDCIGAVAEITRVGTLVVITLGWR 229
18976671  188 VGGIYAVKISL-DNFGGLNGDCIGAVGEITRGATLLILGVWA- 228
14520261  188 VFAWYVIRLSL-ENFGGINGDCLGAMAEITRAGTLVILSFSLC 229
240102595 188 LAGAYVIRLSL-RNFGGLNGDCIGAVAEITRAGALLGMAVVWV 229
57640792  188 LFGVHIIRISL-KNFDGLNGDCLGATAEITRAGTLVVMALVWW 229
212223833 188 AFGGYAIKVAL-DNFGGINGDCIGAIAEITRAGTLLVVAFAGA 229
13541326  198 LIVQLTKTMIS-RRFGGINGDVIGFLGEFSRSLFIFMLIIIAH 239
16082105  197 LIFIIVKMAVI-RRFGGINGDLAGFIGELGRSIFLMISLIMAQ 238
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