4YK8,4J2G


Conserved Protein Domain Family
ATG13

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pfam10033: ATG13 
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Autophagy-related protein 13
Members of this family of phosphoproteins are involved in cytoplasm to vacuole transport (Cvt), and more specifically in Cvt vesicle formation. They are probably involved in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage.3].
Statistics
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PSSM-Id: 431003
Aligned: 98 rows
Threshold Bit Score: 132.715
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4YK8_B         18 HHCFYKTGLIILESRLNvfgt----------------------------------------------------------- 38   Schizosacchar...
XP_003328147   56 HHIYSKSTQLIINARIDq-------------------------------------------------------------- 73  
CCA67418       31 sRFFIKFLLILVSSRSTaie------------------------------------------------------------ 50  
XP_007853743   14 lHLYTKLFYVVNDARAIse------------------------------------------------------------- 32  
EMD36220       13 HRFFLKLAQLVHHARAAapa------------------------------------------------------------ 32  
XP_007397620   13 YRFYTKLALVVHHARATse------------------------------------------------------------- 31  
EPS95097       13 YRFYTKLSLVVHHARATle------------------------------------------------------------- 31  
XP_006675585   36 lNFLSKTAQVIVQSRLTdvsrlarhadgpsfntldsvcpvnnadvqgtvdtgayptsdpaypymdaaavdnpsrasrdsh 115 
EPB88766       97 QNFYTKTAQIIIQSRIPsmk------------------------------------------------------------ 116 
EPB89041       33 QNFYTKTAQIVIQARCTpthdaryg------------------------------------------------------- 57  
4YK8_B         39 ----------srpRESSKNNKW-------------------FNLEIVE--TELY-AEQFKIWKNIELSPS--------Rk 78   Schizosacchar...
XP_003328147   74 ------------pTTDSRHDKW-------------------FNLELPE--PDYF-KEELKTWKSLSASIHslsnsnssNs 119 
CCA67418       51 -----------hgPRSTKVDKW-------------------FNLETPD--TDIH-RDHMRLFRAISSMST---------- 87  
XP_007853743   33 ------------pRTQPKIDKW-------------------FNLETRD--SDLFtKEAKERYKSLSSSPR--------T- 70  
EMD36220       33 ----------staPPSSKPDIW-------------------FNLEIPSpsAKLF-KEPTRPYSSLSSLSK--------P- 73  
XP_007397620   32 ------------pNPQAKADKWvrylrlwkspadpadvvikFNLETPD--TDVF-KEYTRVYRSLSSTVL---------- 86  
EPS95097       32 ------------aPAEAKVDKW-------------------FNLETPD--PEIF-REQTRPYRSISTLE----------- 66  
XP_006675585  116 sarssstqpnslpSKPRKPNKW-------------------FNLEMDD--VEPI-REEMRFWKLHSTGGV--------Q- 164 
EPB88766      117 -----------ntLGKKKLNKW-------------------FNITTSD--NEKL-KEELKFWKSLVKYQQde----eeS- 158 
EPB89041       58 -----kstslkgsTTTKKMNKW-------------------FNIATED--VELL-REDLKYWRTMAVQSTed-----kE- 104 
4YK8_B         79 -----------iP-P-------MVLHTYLDIS--------DLSKN-QTLSVSDGt---------HSHAINFN-------- 113  Schizosacchar...
XP_003328147  120 lknskqqqqqqqPlPnydlipvLIFETILDIQ--------ALPPN-SFITLTDS----------QAREHTVDhripqpth 180 
CCA67418       88 ------------PpT-------LVIHIVLTIP--------ELGSN-KALVALGP----------SDQRVKIE-------- 121 
XP_007853743   71 ------------P-P-------LEIQVLLTIP--------DLTTN-QVLVYNAP----------DTSRVRVE-------- 103 
EMD36220       74 ------------PlP-------FTIQVLLVVP--------KLASN-QVLVHCPP----------GGSRTRLQl------- 108 
XP_007397620   87 ------------PsT-------FQLQVLLAVP--------ELTPN-QVLAHIEP----------DSSRVPID-------- 120 
EPS95097       67 ------------PvPa------FQLQVLLCIP--------DLASN-QVLVYNAP----------NSSRFRID-------- 101 
XP_006675585  165 ------------ShP-------LTIQIYLDIG--------DLPPS-HNLLLKNKa---------SQKRLRIGkefltg-- 205 
EPB88766      159 ------------PpP-------LVIDIYLETTepdllqegDDVHGwRKLDL-------------GIHQNDVQ-------- 198 
EPB89041      105 ------------PpP-------MILDIYLDTS--------SLSHN-QSLVVADDnlrwgcvelkTADAHHID-------- 148 
4YK8_B        114 ------------------NMSTMKIVLERWIVNLDGEAL-----------STPLELAVLYKKLVVLFRSLYTYTHLMPLW 164  Schizosacchar...
XP_003328147  181 pnhptlhhhhqsthslnrPQIHKNIVIERWSVSLLGPFPn---------qPTTLEPPTVYRHSIIHFRALYSHLRTMPGS 251 
CCA67418      122 -------------------PTPRGILLETWTLSATQLAGvsagsslsssdPGELSLAAVYKHAISLFRSLYTLCRQLPAA 182 
XP_007853743  104 -------------------PTPRTILLERWILTFTPRDTrddd---dtdeSWHVAPSTIYKHGIPLFRSLYSLLRILPTW 161 
EMD36220      109 ------------------HPVPTHILIEEWTLSGTSTHPils-----adeDDDSRPSKLYKNGVQLFRWVYTLLYLLPAW 165 
XP_007397620  121 -------------------PTPKFILLETWTLVFEPHQSqshlg--qsqeRSDVAPSTIYKHGISLFRSIFTLLRILPTW 179 
EPS95097      102 -------------------PTPTHVLLESWDLSFRPEPYrn-------ddRSEITPPTIYKHGISLFRSIFTLLRILPAW 155 
XP_006675585  206 ------------tdtagrTIRKTKIILESWQLSVSRNAP-----------ANPPDLPVVYKKSIVFFRSLYSMLRLMPAY 262 
EPB88766      199 -----------------------RILIESWTLSLNHPLP-----------DYPVDLPNLYKRSIVFFRSLHSLVRILPSH 244 
EPB89041      149 -----------------------RILIESWELTLKHPYP-----------EYAVDLPNLYKRSIVFFRSLHSLTRLLPSY 194 
4YK8_B        165 KLKSKIHKLRaHGTS-----LKVGCALStd----------------dVLSNDFLPISAPISSSLGS----SIATFSFSPV 219  Schizosacchar...
XP_003328147  252 TLYQRLKKRTnPEHGl----LKIGCRIStanpcqefslhplqfhhpsSYPHQEIGIYQDLSNSQSHappdSISTYDFPSI 327 
CCA67418      183 RLYQQYRQRAgVTHPspsssFGIDLRL--------------------QLDQGVLAFDPSPSSPWPAw--lQTSSHAFPGL 240 
XP_007853743  162 KLCKRLRRRGsAQVNrg-ngLSIQVRVRe------------------HDDHTMLDFGVPPSPSNAPl---PTSAHSFPSV 219 
EMD36220      166 RVARARRQR-----------FPLQLRVMgd----------------pPLESTFLGFHVFPFL--------STTEYNFSPI 210 
XP_007397620  180 KLARRGGRLRgMNNGn----FSIQVRVEqr----------------sVHMDGVLEFDSLVQGSTL-----AHQVHDFPPV 234 
EPS95097      156 KLARR-RRTGgNRNGn----LTVELRLAgh----------------gQSGGNVLGFDAPPARGASPl---AKETHTFASI 211 
XP_006675585  263 NLCRKLRSIKnTP-------FAIMYRISttrtvffddvgldvlhvnnDMRK-------------------GLVEHTFSGI 316 
EPB88766      245 SLYQRSRLHDgE--------ISLGYRLStt----------------hYNRKDEISLDHALTNVD------TIQLYEFNDI 294 
EPB89041      195 DLYRKLHKSNdATHS-----LSIGYRLSts---------------sgHGKSTEISLDTPIIESDARk---PTKLYEFNDI 251 
4YK8_B        220 GTPAGDFRISVQYRKNC 236  Schizosaccharomyces pombe 972h-
XP_003328147  328 QTSLGSIKTRVIYRNQI 344 
CCA67418      241 STPLGILKISVRYLTQP 257 
XP_007853743  220 PLPMGSLTLTATYLSTP 236 
EMD36220      211 GHPLARLDLCLSVRALC 227 
XP_007397620  235 SHPRGTLSLSTVYLSTP 251 
EPS95097      212 THPTGSLSLSVTYLTAP 228 
XP_006675585  317 ETPLGVISLHVTYRAEC 333 
EPB88766      295 STPLGTFKLKLLFRENC 311 
EPB89041      252 VTPIGTFKLNVNYRRNC 268 
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