Conserved Protein Domain Family
DUF1176

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pfam06674: DUF1176 
Protein of unknown function (DUF1176)
This family consists of several hypothetical bacterial proteins of around 340 residues in length. Members of this family contain six highly conserved cysteine residues. The function of this family is unknown.
Statistics
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PSSM-Id: 461982
Aligned: 24 rows
Threshold Bit Score: 285.432
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015698193     26 QAIYNDWQVSCDNLNHCAARNSQDGQ---EL------VMKITREAGPEGKSSVSIDYQRNSDEqmadAPVANRLQMNGKT 96  Rahnella aqu...
WP_013268551     46 ERTFRDWYAVCDNANGCYAFGRASEG---VG------WVRIAIAAGPDAQPGVVVGFWPENGS----FGGPLTARVDGTD 112 Brevundimona...
jgi:Msil_0781    38 LKQFKDWTVGCDNLRNCVALGLSSES---DMsg---aYLKISRAGAADARPSLSVTLMAEPKS----KAPALRLQFDGAA 107
jgi:Pmen_3175    27 YREIKDWVVACDNLRGCQALSATEDY---GHtp---lRLELRRAAGAQAPLQLSLHYAGQTEY--------FPLLLDGEP 92 
WP_013789670     26 YSNLKDWLVACDNTRQCTALSNATEEdvqKLpt---wSLSVSREAGPEGALHVGLFSYNKASG---------QPLLDGKP 93  Pseudomonas ...
IEC:ABF-0014904  55 QKVFRHWQITCNNLNDCDIRN--------NDpy---lRVTLKREAGAQGKISLDFDLADKRQA----------LYLDGVR 113
Q2YRN7           20 YKQIRDVSVLCDFAANCTLSLNPGTG---ENa----pGIGLYRSSKADSIPELRLSFSEQMPK-----TGKLEILVDGKP 87  Brucella abo...
WP_012091683     30 FKKVRDTLVLCDFAQNCTLTLTPVAS---DGa----pGLGIFRSSQSGSKPLLRLSYVDPSQK-----TGKLEISIDGQT 97  Brucella
WP_025293122     29 VQVFADWAVGCDNVRDCEAQALATEG---EEvp---aFVTVSRRAGAGGQPTIAIPFAAGRRP--------IALLVDGKR 94  Sphingomonas...
BAI98351         29 LESYKDWTIGCDNRNRCEAVSLLPEG---GNwpdapvMLGIVREAGADADPEIWVSRAAKGRE-------TLDFLVDGRK 98 
WP_015698193     97 LsfnhrewdiskKHLS------------TTNRLVVNEFIAAIREGSSIQLAV-KADPAQsvr-pvISLKGIKAALLAIDA 162 Rahnella aqu...
WP_013268551    113 L-----------IAATdavgdeddypaaTVRADQVTRLIDAMGQGEAMTLAA-GTETVT------ISLSGAAASLLWIDE 174 Brevundimona...
jgi:Msil_0781   108 Ag---------lPERPipvrqdgdsvsaPLPPEQVDAFLAALRTAKRLTVRLiDGKTLVdp--afVSLAGSAAALLYMDA 176
jgi:Pmen_3175    93 Lsa-------vaDALQlaqdd--delllSAEGAEAQALLAELRNGEQLRMAV-DGEDEAv-----VSLRGLSAALLLMDS 157
WP_013789670     94 LqvklqpgklteGSVPev---------ySIEGSDAQALIAELRNGQRLVLPT-EEGEAV------TSLSGMSAALLLMDS 157 Pseudomonas ...
IEC:ABF-0014904 114 Fplsqpawqtd--------eeegafyvhTDQLDVIQQFVMAAKNAKRLSLSE-HGGSQGnnqeesISLNGLNAALLLADE 184
Q2YRN7           88 E-----------LDTNiaalkvrnnelvYVDEAGVAKLIGAMKNGQKLQLKL-ADKVSG------YSLSGFVGGLIYLDE 149 Brucella abo...
WP_012091683     98 L-----------LDVDvsalkaqddqldY--TGDVVKALDGMKNGQKLQLKF-AGKTST------YSLSGLVGGLIYVDE 157 Brucella
WP_025293122     95 Wpqplri----------------eddqvRFGAVATDLLLPVLLKADRIELMD-VQGIVVg----rASLTGISAALKYTDE 153 Sphingomonas...
BAI98351         99 I-----------ASVTsvn------geaSVQGPQASALAIAMAKGGGMEIRA-GGRRIDr-----PSLAGSAAALRYMDA 155
WP_015698193    163 QQGRVGTKTAWINRGVKPASTVPP-VPAMPVLPHFSEPHA-----LSETEMSAITQna----atTIENNDCSLDPSEREV 232 Rahnella aqu...
WP_013268551    175 RQGRLGTSMALIRKGDRTASSVPA-GPTVPEVTPAPAVSQg---rYGDQEGQTLPAav----aaLPDVVQCRADTDFNPD 246 Brevundimona...
jgi:Msil_0781   177 QQNRAGTVSALIDKGAAPSNAAAPeEPSIPAVKMTMDRTEpkrp----------------pgvaPATDESCKAYDPI--- 237
jgi:Pmen_3175   158 VQGRVDGVTALYRPGTRPASEVPV-APPAPRLRPYPGTAP-----LAEAESRAIAEavmaatrsAWFEEEMNSTPEAE-- 229
WP_013789670    158 VQGRLGTTTALLRKGNNPASSVPP-APAAPPVPTWQAPKP-----LSEADSKRSLAavreamrsDWQPEMYEDELPEGQ- 230 Pseudomonas ...
IEC:ABF-0014904 185 RQGRLNNLSALLQVGNGEVAQVPP-VPVGQEINPAYTQPPp----LTNAKI--LINgvisakknLLEEEDCGLSKEARQL 257
Q2YRN7          150 QQARDGTVAALQVKGTKP-------APAAPDITLIETVEQipegi---------------rkdfSDDAATCGGASPESFR 207 Brucella abo...
WP_012091683    158 QQSRDGTVEALQVKGSKP-------APVPPQLKLIETVEQipadi---------------rkdfSDEAAVCGGASPGTFR 215 Brucella
WP_025293122    154 AQGRTGTPTAIVDKGDRPAIEVPRrAMPAPIAIPVATRTApp-drLSAGSVRTLR-----------ETNACEAGPDAAPP 221 Sphingomonas...
BAI98351        156 KQGRAGTVAALVATGLLARGAVRP-APPLPTIRRAAVPAGaqppaLWREELTAL-----------GTFTGCADEMRSASS 223
WP_015698193    233 H-----IFALSNDKALMTVNCDMGA-YNLYALGFLVs---RQAPYKMENLALNmpf--klGEEDESPELINADFDPKTGM 301 Rahnella aqu...
WP_013268551    247 LqaaivSAKLDANTVLWGVPCGAGA-YNFANAWFTT----RPDGSNPRRLTFP-------STGEPLDLLVNAAYDPATRV 314 Brevundimona...
jgi:Msil_0781   238 ------VIRLSATETLWGI-CDQAAaYNFAYRFWIAgp-gRPKGASAAVFETPal----aAPDSDSSVVVNPSLSDNGLI 305
jgi:Pmen_3175   230 ------AFALNEHEALVLIRTWCAA-YNCDFAVYRVs---RQPPYEERDLQLDplplehdGLSG------AVGYRPETGE 293
WP_013789670    231 ------AFALSDREALVILKTGCGA-YNCNYSLYQAp---FDQPQQARQASIPeipvfedLPPSG-----SVEFDPASGE 295 Pseudomonas ...
IEC:ABF-0014904 258 Se----AEPLTNELALVMLNCGMGA-YQSSSMLFVTp---RNNPQAAQLLELPrpirpadSREEKIRWFTEADYDPESGM 329
Q2YRN7          208 Lag-gfVTKIADGLNLVGLPCGAPGaYNQPYVFY--------SRYENRIVPVSlpv-isdDGPTTTDSAWNIDWNNRTRT 277 Brucella abo...
WP_012091683    216 Nag-gfETKIADGLDLIGLPCGSPGaYNQPYAFY--------SRYENKTVPISlpt-isdDGPTVTDTAWNIDWTQKTLT 285 Brucella
WP_025293122    222 Ee---sWFRIDERHTLLLLSCGGGA-NNRSALPFIVtnggRKKGLAADYARFDhpt--gyTAEHGQTLLPNPEWDKDAGT 295 Sphingomonas...
BAI98351        224 Pp---eLHRLSKTETLVLVPCGAGA-YNYTSVPVIAtgipGRRVFRFAGFDYQpg----wSEEAGHPMLVNADWAPETAT 295
WP_015698193    302 LSTYDKGRGIGDCGVSSRWVF----DGK-QFRLAAFASEPSCDGYSSGg--EWPVLWVTQ 354 Rahnella aquatilis
WP_013268551    315 IDAFDKGRGLGDCGTASSWTW----TDR-GFVLRSSTAMPDCYGVPSE---YWPTFWVTR 366 Brevundimonas subvibrioides
jgi:Msil_0781   306 LSSNNKGRGVGDCGESAGWAY----DGA-QFRLVSLQRMDECRGVAPD---DWPTLYRAR 357
jgi:Pmen_3175   294 LAYLHKGRGLADCGGAGSWRF----DGE-RFQLASFSFLSRCAGGNPG---EWPELWRVV 345
WP_013789670    296 LSSFTLAMGMGGCGITQRWRY----DGK-GFVPVHATMLGTCLGLDST---YWPVLWRTA 347 Pseudomonas fulva
IEC:ABF-0014904 330 LYHSAKGRGIADCGESAQWVF----DGK-TFQLVAYNYQPECNGGQPG---DWPSVWAMP 381
Q2YRN7          278 LTGFFKGRGIGDCGTYDVWKAvdsgEGRvSFVLKEERAKGDCDGNYAGgpqNWPASWPPK 337 Brucella abortus 2308
WP_012091683    286 LAAFFKGRGLGDCGIYDVWKAtdsgEGRvRFVLVQERSKGDCDGNYAGgpeKWPASWPVN 345 Brucella
WP_025293122    296 ITSRIVGSPSGDCGSSQRFAW----DGE-AFRLIEQRAMSTCRGSL-----QWIRVWTVP 345 Sphingomonas sanxanigenens
BAI98351        296 LQSYAKGRGIGDCGGSEAYVW----DGA-RFRLVEASAMGECRGAW-----HWITTWSAR 345
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