2Q7D


Conserved Protein Domain Family
Ins134_P3_kin

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pfam05770: Ins134_P3_kin 
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain
This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.
Statistics
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PSSM-Id: 368606
Aligned: 5 rows
Threshold Bit Score: 320.175
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2Q7D_A 130 YMEDDRICSPPFMELTsLcGDDTMRLLEKNGLTFPFICKTRVAHGT-NSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVL 208 human
Q33BI9 143 SNAYGEVCTPRQLVIMkD-PLSIPSAVAKAGLTLPLVAKPLVVDGTsKSHELSLAYVETSLSMLDPPLVLQEFVNHGGIL 221 Japanese rice
Q9SUG3 140 SDSNGRVGVPKQLVIKkD-ASSIPEAVNNAGLRLPLVAKPLVADGSaKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVL 218 thale cress
Q7XBW0 118 AHHHHTFGIPSQVVVY-D-AAALSDSGLLAALRFPLIAKPLVADGTaKSHKMSLVYHREGLRKLRPPLVLQEFVNHGGVI 195 Japanese rice
Q9SBA5 109 VSDSERFGVPEQVVVM-D-SSVLSGGGALGELKFPVIAKPLDADGSaKSHKMFLIYDQEGMKILKAPIVLQEFVNHGGVI 186 thale cress
2Q7D_A 209 YKVFVVGESYTVVQRPSLKNFSAGTS--DRESIFFNSHNVSKPESSSV------LTEL--DkiEGVFERPSDEVIRELSR 278 human
Q33BI9 222 FKVYVVGETIRVVRRFSLPDVNIYDL--ENNDGIFRFPRVSCATNTAE------DAEV--D--PSIAELPPKPLLEKLGR 289 Japanese rice
Q9SUG3 219 FKVYIVGEAIRVVRRFSLPDVSRREL--PKSAGVFRFPRVSCAAASAD------DADL--D--PSIAELPPRPLLERLAK 286 thale cress
Q7XBW0 196 FKVYVVGAHVTCVKRRSLPDVSSDVLqdASAEGSLSFSQVSNLPNERT------AQEYydDmrLEDAIMPPTAFINDIAA 269 Japanese rice
Q9SBA5 187 FKVYVVGDHVKCVKRRSLPDISEEKI--GTSKGSLPFSQISNLTAQEDknieygE-----DrsLEKVEMPPLSFLTDLAK 259 thale cress
2Q7D_A 279 ALRQALGVSLFGIDIIINNQT-GQHAVIDINAFPGYEGVSEFFTDLLNHIAT 329 human
Q33BI9 290 ELRRRLGLRLFNFDMIREHGRkDRYYVIDINYFPGYGKMPGYEHIFIDFLLS 341 Japanese rice
Q9SUG3 287 ELRRGLGLRLFNLDIIREHGTrDRFYVIDINYFPGYGKMPEYEHVFTDFLLS 338 thale cress
Q7XBW0 270 ALRRALGLHLFNFDMIRDARAgDRYLVIDINYFPGYAKMPGYETVLTDFFWE 321 Japanese rice
Q9SBA5 260 AMRESMGLNLFNFDVIRDAKDaNRYLIIDINYFPGYAKMPSYEPVLTEFFWD 311 thale cress
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