4WIE,2ZCI


Conserved Protein Domain Family
PepCK

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COG1274: PepCK 
Phosphoenolpyruvate carboxykinase, GTP-dependent [Energy production and conversion]
Phosphoenolpyruvate carboxykinase, GTP-dependent is part of the Pathway/BioSystem: Gluconeogenesis
Statistics
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PSSM-Id: 440885
Aligned: 157 rows
Threshold Bit Score: 1091.35
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4WIE_A        17 MTsati----------------------------------pglDT--APTNHQGLLSWVEEVAELTQPDRVVFTDGSEEE 60 
WP_012865705   1 MTltsdars---------------------------qredqhaAPprTTPLPLPYAEWVEAVAALTQPDEVVWCDGSDAE 53 
WP_013769304   1 MTvttlppa---------------------------vdrtparTG--AATVRRDLRAWVADVADLTEPDAVVWCDGSPAE 51 
WP_082763550   1 MItnpnrp-----------------------------yrttenVV--SGAPRVRLETWVADVARLTQPDRILWCNGSADE 49 
WP_096422098   1 MTlldrprttaphrtpda---------rpeittaanspssapvVL--EADRPADVVAFVERIARLTTPDQIHWVDGSTRE 69 
WP_120789745   1 MTilearp-----------------------------qterrtAE--TPASDSDVRAWVDQVAALTQPERVVWCDGSDRE 49 
WP_120761674   1 MPa---------------------------------------sPT--PVAPVRSLDEWVAENVELLQPDRVVWIDGSRAQ 39 
WP_129205441   1 MPtsiats------------------------------tthatAV--VTPEGGSVEAWVAEVAALTRPDAIVWCDGSDEE 48 
WP_129187330   1 MSttidhh-----------------------------asttarAV--VVPTDGTVEAWVAEVAALTQPDDVVWCDGSEVE 49 
WP_087471192   1 MTtaartartrrtrsaallddvetdlvglvatsgtnpgsavgsRD--GDPRPRDARAWVREIANLTEPDAIVWCDGSAAE 78 
4WIE_A        61 FQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNWMDPGEMRSIMKDLYRGCMRGRT 140
WP_012865705  54 RERLTRLMVERGTLLPLDPDLRPNSYLARSDPSDVARVESRTFVCPEQESDAGPTNIWRDPTLMRAELAAAFAGCMRGRT 133
WP_013769304  52 RQALLDGMVAAGTLIPLDPVLRPGSYLARSDPSDVARVESRTFICSRAQADAGPTNNWRDPDAMRAELAGVFEGSMRGRT 131
WP_082763550  50 IDRLTAEMVSAGKLIPLDESKRPGSFLARTSADDVARVENRTFTCSVDPADAGPTNQWRDAAQMRVELDGVFAGSMRGRT 129
WP_096422098  70 RHALLQQLVAAGTLTQLNPDIRPYSFLARSDERDVARVEERTFICSEREEDAGPTNNWMAPEQMRAELEPLFTGSMRGRT 149
WP_120789745  50 RHELTQVLLDEGKLIRLNGEYRPGSYLARSDPDDVARVESRTFICSTSRDDAGPTNNWVDPDEMKHELTGRFAGSMRGRT 129
WP_120761674  40 LDALLHDMVEEGRIIRLNPEHRPYSFLARSDPDDVARVEARTFICSEREEDAGPTNNWREPEAMREELRGLFAGAMRGRT 119
WP_129205441  49 KQRLLDGMVESGTLIKLDEAKRPRSYLARSNPADVARVESRTFICSEREEDAGPTNNWRSPAAMGSELRDVFAGSMRGRT 128
WP_129187330  50 KQRLLDEMVDAGTLVRL--AKRERSYLARSHPSDVARVESRTFICSERQEDAGPTNNWRDPRLMGRELHAVFAGSMRGRT 127
WP_087471192  79 KQRLTDLLVDAGTLLPLDPELRPGSYLARSDPSDVARVESRTFICSRDEVDAGPTNNWREPEVMRAELRGVFDGAMRGRT 158
4WIE_A       141 MYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMTRMGKAALEKMGDDGFFVKALHSVGAPLEPGQ----KDVAWPCSE 216
WP_012865705 134 MYVVPFSMGPVGGPLSQVGIEITDSPYVVVSMSIMTRTGSDVYRLIRDGAPWVPAVHSVGAPLVEGA----DDVPWPCSD 209
WP_013769304 132 MYVVPFSMGPLGGPISQLGVQLTDSPYVVVGMQTMTRVSRRVVAMIDAGASFVPAVHSVGAPLRTVSgtavADVPWPCND 211
WP_082763550 130 LYVVPFSMGPIGGELSQLGVELTDSPYVVISMAKMSRLGDRILREIDAGVPWVATVHSVGVPLRDAEgaetADPVWPSNP 209
WP_096422098 150 LYVVPFAMGPIGSSMTRYGVQLTDSPYVVVSMGTMTRLGSAALAQIVRGQSWVPAVHSVGAPLNNGQ----KDVPWPCNE 225
WP_120789745 130 LYVVPFSMGPVGGRLSKLGVQLTDSAYVALSMHIMTRVGTGALALIDAGQSWVKALHSVGSPLIDDDgarhPDSEWPCNP 209
WP_120761674 120 MYVLPFSMGPVGGALSRYGVQLTDSAYVVASMSIMTRVGDAVLERIRAGARWVPALHSVGAPLEPGD----EDVAWPSNP 195
WP_129205441 129 MYVVPFSMGPVGGPISQVGVEITDSPYVVVSMHLMTRVSRDVLDLISGGQQWVPAVHSVGAPLAPAE----QDVPWPCND 204
WP_129187330 128 LYVVPFSMGPLGGPISQVGVEITDSPYVVASMHVMTRVSRDVLALIDAGHEWVPAVHSVGAPLGPTD----TDVAWPCND 203
WP_087471192 159 LYVVPFSMGPVGGPISQVGIQVTDSPYVVVSMGIMTRVGTTVMDLIDAGAPFVPAVHSVGAPLVDDTgavaEDVPWPCND 238
4WIE_A       217 TKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAM 296
WP_012865705 210 LKYVSHFPETREIWSYGSGYGGNALLGKKCFALRIASVIGRDEGWLAEHMLLVRVTSPEGRVFHLAAAFPSACGKTNLAM 289
WP_013769304 212 TKYIAHFPETREIWSFGSGYGGNALLGKKCFALRIASVMGRDEGWLAEHMLLVRLTSPQGRRYHVAAAFPSACGKTNLAM 291
WP_082763550 210 TKYIVQFPETREIWSFGSGYGGNALLAKKCFALRIASVMGRDDGWLAEHMLLIKVTSPENHAFHLAAAFPSACGKTNLAM 289
WP_096422098 226 TKYIAHFPKEREIWSYGSAYGGNAILAKKAFALRIASVMARDEGWLAEHMLLIKVTSPAGKKYHMAAAFPSACGKTNLAM 305
WP_120789745 210 DKYIAHFPDTREIWSFGSGYGGNALLGKKSFALRIASVIARDEGWLAEHMLLIKLTSPVGRPFHLAAAFPSACGKTNLAM 289
WP_120761674 196 VKYICHFPETREIVSFGSAYGGNAILAKKSFALRIASVMARDEGWLAEHMLLLRVTDPRGRRFHIAAAFPSACGKTNFAM 275
WP_129205441 205 DKYIVHFPESREIWSYGSGYGGNALLGKKCFALRIASVMARDEGWLAEHMLLIKITSPQQRTYHLAAAFPSACGKTNLAM 284
WP_129187330 204 TKYIAHFPESREVWSYGSGYGGNALLGKKCFALRIASVMGRDEGWLAEHMLLVRVTAPTGRRYHLAAAFPSACGKTNLAM 283
WP_087471192 239 TKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASAMARDEGWLAEHMLLIRATSPEGRAYHLAAAFPSACGKTNLAM 318
4WIE_A       297 LQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIaAGNTVFTNVALTDDGDVWWEGLE 376
WP_012865705 290 LRPTVPGWTVETVGDDIAWMRPDDEGRLRAINPEAGFFGVAPGTGPSTNPAAIATI-ARDTIFTNVALTDDGDVWWEGLT 368
WP_013769304 292 LTPSLPGWRVETLGDDIAWLRAGPDGTLRAINPEAGFFGVAPGTSVATNPAAIATL-DHDTVFTNVALTPDGDVWWEGLT 370
WP_082763550 290 LRSTIPGWTVETIGDDIAWLKKGEDGRLHAINPEAGFFGVAPGTGYDTNPTAMETI-EADTIFTNVALTDDGDVWWEGMT 368
WP_096422098 306 LTPTTPGWTVETIGDDIAWLHIGKDGRLRAINPEAGFFGVAPGTGISTNRTAVDTL-WGNTIFTNVALREDGDVWWEGLT 384
WP_120789745 290 LRSTLPGWRVETLGDDIAWLRQGEDGRLWAINPEAGFFGVAPGTGESTNPNAIETI-WGNTIFTNAALTDDGDVWWEGMT 368
WP_120761674 276 LRSALPGWQVETLGDDIAWLAPGSDGRLRAINPEAGFFGVAPGTGPDTNPTAIDTL-WGNTIFTNVALREDGDVWWEGLT 354
WP_129205441 285 LRPTIPDWKVETLGDDIVWMRPGPDGRLRAINPEAGFFGVAPGTGVDTNPTAIATL-GHDVIFTNVALTDDGDVWWEGLT 363
WP_129187330 284 LQPTLPGWSVETLGDDIVWMRPDDDGALRAINPEAGFFGVAPGTGVDTNPTAIATL-EHDVIFTNVALTDDGDVWWEGLT 362
WP_087471192 319 LRPTIPGWTVETIGDDIAWLRPGPDGRLRAINPEAGFFGVAPGTGAETNPAAVETF-ARDTIFTNVALTDDGDVWWEGLT 397
4WIE_A       377 GD-PQHLIDWKGNDWYfR---ETETNAAHPNSRYCTPMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQH 452
WP_012865705 369 DTpPDHLVDWLGQDWT-P---ASGRPAAHPNARFTVSAAQCPTIADTWEDPAGVVVDAIVLGGRRATNVPLVAQAFSWEH 444
WP_013769304 371 PEpPEGLVDWTGQPWE-P---GCGRPAAHPNSRFTVAAAQCPTIADSWEDPDGVPLDAIVFGGRRATNVPLVAQAHSWEH 446
WP_082763550 369 KEaPAHLIDWTGDDWT-P---DSGRPAAHPNSRFTVSIDRCPTLAED--AHTSFPIDGILFGGRRATNVPLVAQARDWTH 442
WP_096422098 385 DTpPARLIDWRGEEWT-P---DSGRPAAHPNSRFTVAAHQAPSIADTWDDPEGVVIDAIIFGGRRRALAPLVVEARDWDH 460
WP_120789745 369 DTvPGHLLDWTGADWH-P---GLGRPAAHPNARFTVSAAQCPSIAGDWEAHDGVPIDAIIFGGRRASNVPLVLEARSWDH 444
WP_120761674 355 KTpPAGLTDWRGEPWT-P---DAGRPAAHPNSRFTVAASQCPSIAPDWDDPNGVPIDAIIFGGRRATNVPLVVEARDWEH 430
WP_129205441 364 PEaPAHLIDWTGQDWT-PadgAAGRPAAHPNSRFTVAAAQCPSIAPDWEDPAGVPVDAIVFGGRRATNVPLVVQASGWDH 442
WP_129187330 363 PEaPEHLVDWTGADWT-P---GSGRPAAHPNSRFTVAAAQCPSIAPDWDDPAGVPVDAIVFGGRRATNVPLVTQAFGWDH 438
WP_087471192 398 PEpPAHLIDWTGQDWT-P---DSGRPAAHPNSRFTVAAAQCPTIADSWEDPEGVPIDAIVFGGRRATNVPLVAQAYGWEH 473
4WIE_A       453 GVFIGATLGSEQTAAAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADe-sKLPKVFFVNWFRRGDDGRFLWPGF 531
WP_012865705 445 GVFLGATISSERTAAAEGTVGELRRDPFAMLPFCGYDMADHWAHWVETGSRLSd-qGRPLIFSVNWFRTGEDGRYLWPGF 523
WP_013769304 447 GVFLGATVSSEQTAAAEGTVGELRRDPFAMLPFCGYDMADHWAHWLRVGATLDp-aTRPLVFQVNWFRKDAAGRYLWPGF 525
WP_082763550 443 GVFMGATISSEQTAAAEGTVGELRRDPFAMLPFAGYNMADYWSHWLDIGRQLGt--RAPQIFQVNWFRKDADGAFLWPGF 520
WP_096422098 461 GVFMGATISSEQTAAAEGTVGQLRRDPFAMLPFAGYNMADYFAHWLDFGKRLRrsaRVPRVFQVNWFRKSPEGKFLWPGF 540
WP_120789745 445 GVFLGATIASEQTAAAEGAVGALRRDPFAMLPFCGYNMADYWAHWVSVGERLGa--NAPKIFQVNWFRKGADGRYLWPGF 522
WP_120761674 431 GVFLGATIASERTAAAEGELGELRRDPFAMLPFCGYNMADYMQHWLDVGTRLRrtgGVPGVYQVNWFRKDADGKWLWPGF 510
WP_129205441 443 GVFLGATISSERTAAAEGTVGELRRDPFAMMPFCGYTMADHWAHWLEVGDGLEa-eNRPAIFQVNWFRKGADGRFLWPGF 521
WP_129187330 439 GVFLGATISSERTAAAEGTVGELRRDPFAMMPFCGYAMPDHWAHWLTMGDRLNp-aRLPAVFQVNWFRKGAGGRWLWPGF 517
WP_087471192 474 GVFMGATISSEQTAAAEGTVGALRRDPFAMLPFCGYNMADHWAHWLRVGASLDp-dKRPKVFQVNWFRKDADGRFLWPGF 552
4WIE_A       532 GENSRVLKWIVDRIEH-------------------KAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALAVDADEWRQEL 592
WP_012865705 524 GENSRVVEWIARRTETrdpvtspvgrspaelppraRAASVPSPLGLVPAPGALDLDGLGLSEETTAALFAVDPVSWAEEV 603
WP_013769304 526 GENVRVLAWIVEQVDRarg-------------ertDVGAVPSPVGLLPAPGALDTSGLDVTDEDLRALLDVDPRTWAVEA 592
WP_082763550 521 GENSRVIEWIVRRIEK-------------------RISFVESPIGRLPREGDLDLDGLDLEAQDLDALFAVDPESWLDEC 581
WP_096422098 541 GENGRVIEWMVARLES-------------------EACIDETPLGGIPRQGELNVAGLDLPEEDLTELFRMDTDELEAEA 601
WP_120789745 523 GDNIRVLEWIASRLEGt------------------EPAAVDGPLGRVPADGALDVSGLGLTDADLDELFAVDPAAWQAEA 584
WP_120761674 511 GENGRVLAWIVERIAG-------------------EAPASDTPLGRIPAVGTIDYRAAGVGDADWQELFRVDAPALLAEA 571
WP_129205441 522 GENSRVIEWIVQQLDRara-------------vrtDTGAVRSAVGLLPAPGALDTEGLDVSADDLQALFDVPTEAWRTEA 588
WP_129187330 518 GENSRVVAWIAEQVDAahh-------------vrpDAGAVDSPLGRVPAPGALDVDGLGLPAADLAELFHVDRAAWRHEA 584
WP_087471192 553 GENSRVLAWIAAQVDRsrg-------------vrtDCGAVKSPVGLLPAPGALELGGLHLDDGDLDALFDVSPEQWLAEA 619
4WIE_A       593 PLIEEWLQFVGEKLPTGVKDEFDALKERLG 622
WP_012865705 604 RSTEEFFRRFGDRVPPALHAELAALRGRLA 633
WP_013769304 593 DLTEDFFAGFGDRVPAALHHQLALLRERLS 622
WP_082763550 582 DLTEEFFAGFGDRVPDEFADVLRSMRYGLR 611
WP_096422098 602 DDVEHFFQTFGDKLPAELRHQLSHLRSRVR 631
WP_120789745 585 DLTEEFFAGFGDRVPTELHAQLAELRSRLA 614
WP_120761674 572 DDTEAFLDRFGDKLPEAVRRQLAALRERLG 601
WP_129205441 589 DLTEQFFDTFGDRVPQRLRDQLADLRERLA 618
WP_129187330 585 DLTEAFFAELG-HVPDRVRAQLDALRARLT 613
WP_087471192 620 ELTAEFFDTFGNRVPDELWAQLARLRDRLG 649
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