1X1O,5HUP,3TQV,3L0G


Conserved Protein Domain Family
NadC

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COG0157: NadC 
Nicotinate-nucleotide pyrophosphorylase [Coenzyme transport and metabolism]
Nicotinate-nucleotide pyrophosphorylase is part of the Pathway/BioSystem: NAD biosynthesis
Statistics
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PSSM-Id: 439927
Aligned: 934 rows
Threshold Bit Score: 116.271
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1X1O_A        14 L-EEALRAWLREDLGQGDLTSLLVvpEDLEGEAVILAKEGGVLAGLWVAERVFALAdpRT-AFTPLVAEGARVAEGTEVA 91 
WP_013122007   4 FtQADIDQLILEDLPLHDETTRALalPDVPGSLTYCARQPGVLAGLAPLLRLAQSL--GL-RPEPLAADGDATAPGQAVL 80 
WP_011139606   1 MvNQEIERLWREDADYIDWTTLGLgiGEKRGEISFSAKRGGVISGIKEALSLGEAC--GV-ELEALVKEGAWVEAGEEIL 77 
WP_011139663   4 IlDSQLEKILEENAPFGDLTTQVLgvKNRHTEIVIIAKNDIISSCTEEAVRIFELT--GS-KASLISRSGDRLGKGEVLL 80 
WP_014026824   1 mpRRLLEEWLFEDVGRGDLTSTVLglRSVKGVAELYVRESCIVACSEEAGEVYRIA--GAeNVEVLVESGSMVEPGTVVL 78 
WP_014126184   1 -mRSRLEAWLLEDLGSYDLTTEVLgiGGLRGVAQLFAREEAVVAGSEEAAEVYRLA--GCgEVEVVKRSGQLARRGNVVL 77 
WP_014737738   5 LfDSELESLLRDDLHHLDLTTVYMgvESERGVARLVSRSRGVLAGVEEAADVYEKA--GA-TVGYLLGSGSEVSSGAVVL 81 
WP_014770351   1 -----MMDILEEDIGLIDITTEGLgfGAKAAKISFAPKTEVIVCGVELVEQMCQRL--GL-ETQCFKQCGDKVRADECVL 72 
WP_055408362  12 TpTSLIDEWIREDTAYTDFTTGVLgiSWAPGRARLTTRERIVACGLREAAIVYERL--GA-KARLLHPEGEWAEPGTALL 88 
WP_075798304   5 IpTARLESMLQEDSPYGDLTTLGLgiGELHGRLSMTAGALMTVCCTEEAETLFRLA--GCeEVQSFCRSGAQVEEGSPIL 82 
1X1O_A        92 RVRGPLRGILAGERLALNLLQRLSGIATLTRAYVEALAG--TKAQILDTRKTTPGLRALEKYAVRVGGGRNHRYGLFDGI 169
WP_013122007  81 RLHGNAHALHMAWKQGMNLLEYLGGIASATRQMVDAARAgnPRIQVAGTRKAHPGARKLQHYAVLCGGGMVHRAGLSETI 160
WP_011139606  78 RGEGKAIALHKAWKVTQNLLEYLSGIATFTHEMVTCAKKinPSIEILTTRKNFPGSKRLMLQAILSGGAWPHRLGLFDSV 157
WP_011139663  81 VAEGECENIMLGWRAAQGLLEYCCGVSTLADRFTQKLKEsaLPIALLFNTQSIPSTRKFASKAALSGGAMPHRLGLSDSI 160
WP_014026824  79 RAEGRGDALHAAWRVAQVIVALCSGVATKTWRMVRKAREanPKIAIVTTRKAPPGLRPLYFKAVIAGGGMPHRAGLDDTV 158
WP_014126184  78 RAVGEARCLHAAWRTAQEVVAWASGVATKTRRLVELARRvnPRVVVAATRKTPPGLRALYHKAVLAGGGMVHRCCLSDGV 157
WP_014737738  82 EAEGRASSLHAAWRVAQALVSYMSGVATYTRLMVEAARRvnPRVVVATTRQTPPGLRRLWLKAVLAGGGVVHRQSLSDEI 161
WP_014770351  73 EAYGRADAVHKVWKASQNLLEFLSGIATKTNHMLLLARLhqPHIELLTTRKIFPRTKALALKAVYAGGGAHHRLGLYDSI 152
WP_055408362  89 EAEGPAAALHAAWRLAQTIASIGSGVATYTRRLVERARAanPRIVVAVARKAPPGIRHVYYRCVLCGGATLHRLGLSETI 168
WP_075798304  83 QARGPASALHRATKTAQTLLELTSGIATAAARLRATARQihPEIAVACTRKHLPGAKDVMLRAITAGGCVPHRLGLSDSV 162
1X1O_A       170 LLKENHVRAA-GG---VGEAVRRAKARA-PHYLKVEVEVRSLEELEEALEAG-ADLILLDNFPLEALREAVRRVG---GR 240
WP_013122007 161 LVFAQHRAFL-PDl-dAAQLVARAKAH--SPEKFVLIEAESADDALVAARAG-ADGVQLDKMSPEQLTALVPQLRalqPR 235
WP_011139606 158 LVFEQHRVFL-ETpaeLEQAFKALKRR--LLEKKIAVEVSDFEEAKLFASWG-ADILQCEKMELGELARCVE-LKrayPS 232
WP_011139663 161 LIYPEHLKLF-KSkeeARNQISQIKAA--LPGKKIILEARSEKEALEAMQFE-VDALQLDRFSPSSLKKICSKIQglkPE 236
WP_014026824 159 LLFDNHWVLLrGG---FSEALERLRASNvGALRSWGVEVRSVEEALEAIAAG-AQFIQFEKVKPDLLRQFVRVVRekaPH 234
WP_014126184 158 LVFRNHLVFL-GD-----GALQKAARA--VAVRPAGVEVSTVEEAVEAAKAG-FSYIQLERMTPEEVAEAAARIRavnPR 228
WP_014737738 162 LLFRNHLVFA-GGr-gLGEVVRSLKAR--VGYKRVGVEVGSLEEALEAVEAG-ADYVQFDHVDPATLRSWVSRLRsefSG 236
WP_014770351 153 LVFKQHRVFF-ESkeaFEAQFAKMKQK--FLEKKIAVEVENYEEALYFAHLG-TDILQCEKMDFETLKRCVA-LKknfPS 227
WP_055408362 169 LVFRNHVVFL-GGlekALERLHRAKSQ--IGERSVVVEAETPEDALLAAKSGvVDEIQLDHIEPRRLKELVEELRsvnPG 245
WP_075798304 163 LVFAQHRGFL-Grq-pPHLWVAQLRAA--QPERKIAVEAGNVDEAVQFAHSG-ADILQCDKFSPEQIGEVVRALNghpQR 237
1X1O_A       241 VPLEASGNMTLERAKAAAEAGVDYVSVGALTHsAKALDLSLLVVR 285
WP_013122007 236 LTINAAGGIRPDNAAAFAASGVDVLVTSSLYN-AKAADFGAVMQR 279
WP_011139606 233 LLLSATGGVKIENVMKIAQSGVDFVVTSAPYH-ANPLDIKVRMKK 276
WP_011139663 237 IALLAVTNTEARFFEEYIMEGISGIVSGAIFY-APPAELKVTISR 280
WP_014026824 235 VKIGVAGGIDDHNVAEYAATGVDFIVTSAPYH-ASPVDVGTRMKR 278
WP_014126184 229 VVVGASGGIDEHNIASYA-PHVDVVVTSAPYR-APPIDLGTEMAP 271
WP_014737738 237 VSIGVGGGVDLENVGEYAATGVDVIVTSAPYH-AKPLSFTTIMER 280
WP_014770351 228 LLLSATGGIGEHNIEDFAKTGVDFIVTSSPYH-AKPSDIRVTIEM 271
WP_055408362 246 IRVAVGGGINLDNVAEYAAAGADVLVTSAPYW-AKPADLTTRMEP 289
WP_075798304 238 PVLIATGGIGDRNIADYARAGVDVIATSAPYT-APPLDVRVTIER 281
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