1UBH,6GAN,6G94,5MDK,4C3O


Conserved Protein Domain Family
NiFeSe_Hases

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pfam00374: NiFeSe_Hases 
Nickel-dependent hydrogenase
Statistics
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PSSM-Id: 459789
Aligned: 150 rows
Threshold Bit Score: 535.145
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1UBH_L           41 RGLEIILKGRDPRDAQHFTQRTCGVCTYTHALASTRCVDNAVGV--HIPKNATYIRNLVLGAQYLHDHIVHFYHLHALDF 118 Desulfovibri...
jgi:Dehly_1288   38 RGWEKILQGRDPWDAPYVTSRVCGVCEGVHTIASNQAIEDAFGI--ELTEAGRLMRNLFSAGYYVHDHFIHFYVLSALDF 115
Q3ZA88           38 RGFEIFMKDRDPRDAVHITQRICGVCPTSHGTTAALNLDSAFGVadKIPNNGRILRNLIQGANYIASHIVHFYHLAALDY 117 Dehalococcoi...
jgi:Dehly_0025   38 RGFEIFLKGHNPTDAQHYTQRICGVCPTSHGMTAVLNLDSAFGVddKIPDNGRIIRNLIQGANYIQSHILHFYHLAALDY 117
Q6ARY7           39 RGFEQILQGRSPLDAQQIVQRICGVCPVSHGIASVLAQEQAYGI--QLPENARLQRNIMLASNYIQSHITHFYHLSALDF 116 Desulfotalea...
jgi:Deba_0998    39 RGFENILRGRDPLDAQQITQRICGVCPISHGLASILAQEQIYNP--ALTPNGVIARNLILGANYIQSHLIHFYQLSALDF 116
jgi:DaAHT2_0520  37 RGFEIFLRGRDPLDSQQITQRICGVCPYAHAIASSTAQENAYRL--QVPPNGRILHNLIQGANHLYDYLLHFYQLCALDY 114
EIM63493         37 RGFEVFLLGRDPLDAQQITQRICGVCPYAHAIASSYAQEAAYRL--RTPPNGRILHNLIQGANHLYDYLLHFYQLSALDF 114
WP_014959255     37 RGFEAFLRGRDPLDAQQITQRICGVCCYAHAVASSYAQESAYNL--SVPPNGRILHNLIQGANHLYDYLLHFYQLSALDF 114 Desulfobacul...
WP_013505084     39 RGIEKALKGFDARVAQHITQRTCGVCPYAHAEASALALESAMGI--RPNVNGQLLRNLTVGVYQIKDHLLHFYTLCALDF 116 Desulfurispi...
1UBH_L          119 VDVTAALKAdpakaakvassisprKTTAADLKAVQDKLKTFVETGq---LGPFTNAYflgGHPAYY-LDPETNLIATAHY 194 Desulfovibri...
jgi:Dehly_1288  116 LDIMAIASY---------------EGSDPGLLAVKSKIVGLVSAGd---TSPFTPRY---TPDEFSvNDPETVTTLVSHY 174
Q3ZA88          118 VDVTEVADY---------------DGTDPELLKVKDFIARALAAGdmsmLAPFYPRY---EGDYr--LPKKVAQAAVAHY 177 Dehalococcoi...
jgi:Dehly_0025  118 VDVTAVADY---------------SGNDAGLTKVQQFISRALAAGdysmLGPFWPRY---EGDYr--LSKAINVKAVQDY 177
Q6ARY7          117 IDITAILDY---------------KGGDAFLLAMQNWVKAELASKnlfpAAPFLPRY---QGRYLK--DVDFNITALRNY 176 Desulfotalea...
jgi:Deba_0998   117 VDVTAILGY---------------HGADPALNDLRDWVSGQRKAGaispGAPFLPRY---AGHYi--QDAGLNVGALKHY 176
jgi:DaAHT2_0520 115 VDITAVLEY---------------TGKDRELSKVRDWVKAEIDSGkrypAAPFLPRL---SGKYLD--NRDANLGAIKNY 174
EIM63493        115 IDVTAITGY---------------TGKDRDLTHLKEWVNHALGSGdshpAAPFLPRL---SGTYVT--DADINITALKHY 174
WP_014959255    115 VDVTAILEY---------------KGSDSDLTVLRDWVKTELNSKtafpAAPFLPRL---SGRYLS--DAQVNIGALKHY 174 Desulfobacul...
WP_013505084    117 IDITAVLEY---------------RGNDQALLQVKSWVQHELANNkvfpAAPFLPRY-----EATYcSDHEVNISGIKGY 176 Desulfurispi...
1UBH_L          195 LEALRLQVKAARAMAVFGAKNPHTQfTVVGGVTCYdaLTPQRIAEFEALWKETKAFVDEVYIPDLLVVAAAYK--DWTQY 272 Desulfovibri...
jgi:Dehly_1288  175 LKAIELKAKSQKMLSYLTGIQPHPNaLMPGGCTAT--PSVEVLQDLRKLWQEQADFVNNVYVPDVMAVGYG-PllPLAAS 251
Q3ZA88          178 VEGLNMRRLAHEMSAIYSGRLPHSVaVVAGGVTSH--PSIDSISNFMSKLNTLRNFIDNVYIPDVIAVAESYP----DYF 251 Dehalococcoi...
jgi:Dehly_0025  178 VEALNMRRIAHEMSAIFSGRMPHSPaLVVGGATQG--PTEDNIVAFRAKLTKLRKFTDEVYIPDVIAVAEAYS----DHF 251
Q6ARY7          177 FIALEMRATAHQLIAIFAGKMPHMAsIVPGGITEK--VTTKKIIQCKSKLAQLKGFINNSYRNDLLAITAEFP----SYL 250 Desulfotalea...
jgi:Deba_0998   177 LQALDMRALAHQAVAIWAGKVPHATaLAPGGVTEQ--VSAKKIAAYAAIIDQLRVFIDTAYLPDILAVATAFP----EYF 250
jgi:DaAHT2_0520 175 LEAMKMEQKANQAAAIFGGKFPHATaIFPGGCTQE--ARVDLIVPYQSLIREVRDFIHHKYIPDVLAVAGAFP----EYW 248
EIM63493        175 VESLEIQKKANRASAIFGGRFPHATgIFPGGCTRP--PDIDAISSYQALIHEVKHFIHHKYLPDLLAVAGAFP----EYW 248
WP_014959255    175 IESLEIQKKANRASAIFGGKFPHATaIFPGGCTQS--PTIDNIASYRSLIFEVRNFIHQKYIPDILAVAKEFP----DYW 248 Desulfobacul...
WP_013505084    177 LDAIEIMAQLHKMVAIFGAKAPHPVaIEAGGVTTM--PTVDRLAHFGTLLSHCTDFVRNRYGNDVLAVAKAFP----AYF 250 Desulfurispi...
1UBH_L          273 ggTD---NFITFGEF---PKD----EYDlnSR-----FFKPGVVF-KRDF-K--------NIKPFDKMQIEEHVRHSWYE 327 Desulfovibri...
jgi:Dehly_1288  252 gfGAtngNYLAFPML---PQGgsasAGDi-SFggsnpMFRGGVVKaNGER-AsrtdisnlTVEDVDYSQITESVTYSWYD 326
Q3ZA88          252 giGVgcgNLLSYGVF---DLEasgtNLAtr-----qrLFTQGVVSaSDLAhR-----------TFDPSKITESIKYSWFK 312 Dehalococcoi...
jgi:Dehly_0025  252 dqGFgtgNVLSYGVF---DLDgkekDLAkr-----qrFLPQGIASgLSLG-------------TFDPQKITEDVKYGWFS 310
Q6ARY7          251 siGKscgNFLSFGAFgdaNLEks-------------pLLPAGALlq-------------gKLEEVDDISIKEDVSFSKYS 304 Desulfotalea...
jgi:Deba_0998   251 qhGAgpgDFMAYGVF---PQEdg-------------fLLPAGRVsh-------------gQAASLDLTKITEQTTHSLFS 301
jgi:DaAHT2_0520 249 diGRsqgGFLSYGHLplgPEPds------------rrLLAPGVMfd-------------gQVEAVDFNQIRQDVGNAKYS 303
EIM63493        249 hiGQskgGFMSYGLLpfgPEPds------------prLLSPGVLid-------------gKVETVKTGAITEDVKFAKYS 303
WP_014959255    249 niGKsrgGFLSYGLLplgPQLds------------krLFAPGVLfq-------------dNFARVDFDAIQEDVKYSKYS 303 Desulfobacul...
WP_013505084    251 keGKgygNTLSAPYL---PDGng------eNF-----FFAGGVTig-------------gSYRPLDLGKITEDHSYAYYH 303 Desulfurispi...
1UBH_L          328 gAEA---RHPWKGQ---TQPKYtdlhG-----------DDRYSWMKAPRYMGEPMETGPLAQVLIAYSQG-HPKVKAVTD 389 Desulfovibri...
jgi:Dehly_1288  327 yPAGvdaLHPSEGV---TDFnl--------------qkQDAYSFLKAPRYNAETMEVGPLARGMVNQF-------PELVD 382
Q3ZA88          313 ---GdttEYPLNEV---TEPef--------------tkADGYSWLKAPRYDGTPYEVGPLARMVVNYVSG-DPLVQQMVN 371 Dehalococcoi...
jgi:Dehly_0025  311 sg----sGYPGDTD---TVDdp--------------nkTGAYTWLKAPRYGGDVYEVGPLPRVLVAYLSG-DPTAQKLVN 368
Q6ARY7          305 ----------SDSGrekTVPep--------------hkSGAYSWIKAPRYRGEAMEVGPLARLMVAQAKG-NKKMQEASN 359 Desulfotalea...
jgi:Deba_0998   302 ---SpsgLHPTKGQ---TIPap--------------rkSGAYSWLKAPRYDNRPQEVGPLARILVAYQAG-QAQVREMVD 360
jgi:DaAHT2_0520 304 ---SpsnLRVRDAA---ITPqp--------------nkRDAYSWIMAPRYAGQVVEVGPAARVMVDYAQGhNPEIKKLVD 363
EIM63493        304 ---SpsgLKVTQGR---LTPap--------------hkEGAYSWVKAPRYGGHVLEVGPAARILVDYLQGgNETVKQLVD 363
WP_014959255    304 ---SpsgLKVRNGE---LTPss--------------hkTGAYSWVKAPRYQEKMVEVGPAARILVDYHQNnNPKIKQLVD 363 Desulfobacul...
WP_013505084    304 -NGSsplLRPLQTD---TLRPL----SardfeveqgkvDGKYSWNRAPRYDGHAMEVGPAARVVNTYRSGsNPELTAMVN 375 Desulfurispi...
1UBH_L          390 AVLAKLGVGPEALFSTLGRTAARGIETAVIAEYVGVMLQEYKDNIAKGdnvicAPW-----EMPkQAEGVGFVNAPRGGL 464 Desulfovibri...
jgi:Dehly_1288  383 -FFNAGGr-----eGVVARHLSRAVISKQIINDGLAWIDRLIEMRLAG-----PLVgmnekPVPkTGRGMGVWDAPRGAL 451
Q3ZA88          372 DTLSHFGAGPAALFSTLGRHAARALECKIVADEMVKWLMELKIGEPVIad----------yEIPeTAEGMGLWEAPRGAL 441 Dehalococcoi...
jgi:Dehly_0025  369 DTLAHFGAPASALFSTLGRHAARALECKMVADAMDKWLDELKPGEPVNvt----------aDIPdSAQGMGLWEAPRGAL 438
Q6ARY7          360 AFLQKTDLSLTDLDSCLGRHIARFIELEVIIEKCEEWMEQLRPDQPTAvd----------fNIPqQAEGRGMMEAPRGAL 429 Desulfotalea...
jgi:Deba_0998   361 QLLGALGRQPAELNSAMGRHAARAIECKLVAEACARWINQLKPGEPTYad----------fDVPaSGAGAGLIEAPRGAL 430
jgi:DaAHT2_0520 364 RFAGQAGIQPTQLNSVLGRHLSRAILAAVLADFLLAESQRLQPGQPTMas----------iDPPaSAEGFGATEASRGAL 433
EIM63493        364 RFAGMADIRPEQLNSVLGRHLCRAVSAVVIADFLLDQTEQINPSAPFIpe----------iKIPeAGEGFGLTEASRGAL 433
WP_014959255    364 KFAGLAGIKAENLNSVLGRHLCRAISAAVIADFLLEETERIDLKGQHMaq----------yNLPkSGEGFGATEASRGAL 433 Desulfobacul...
WP_013505084    376 RLNRELGITIDDYPSVMGRHLSRYILADLTLRHMERQLAEVRPDVLGFth----------hPVPvNARGVGITEATRGAL 445 Desulfurispi...
1UBH_L          465 SHWIRI-EDGKIGNFQLVVPSTWTLGPRCDKNKLSPVEASLIGTPVADAKRPVEILRTVHSFDPCIACGVH 534 Desulfovibrio vulgari...
jgi:Dehly_1288  452 GHWIEV-DNWRIKNYQMVVPSTWNAGPRDENGVKGPYEQALIGAPVPDLDNPINVVRIIRSFDPCIACAVH 521
Q3ZA88          442 GHWIKI-ENHKISNYQCVVPTTWNCSPKDNQGVYGPVEQALIGTKVRDNDNPFELVRIVRSFDPCLACAVH 511 Dehalococcoides mccar...
jgi:Dehly_0025  439 GHWISI-KDQKIERYQCVVPSTWNCSPRDNNDQPGALEQALIGAKVKDEANPFEVVRIVRAFDPCLACAVH 508
Q6ARY7          430 GHWVTI-EKQKIGRYECIVPTTWNCSPKDDKQIPGPVEQSLIGTIVADKTNPLEAARIVRSYDPCLACAVH 499 Desulfotalea psychrop...
jgi:Deba_0998   431 GHWIEI-ADYRIANYQCVVPTTWNCSPRDDAGVPGPVESSLEGLPVADPQNPLEAARIVRSFDPCLACAVH 500
jgi:DaAHT2_0520 434 LHYIRI-ENYKIAKYECVVPTTWNASPRDDQGQPGAMESALIGTRVNNPEEQIESKRIVRSFDPCLACAVH 503
EIM63493        434 LHYIRI-RNYKIDHYECVVPTTWNCSPRDDTGRPGALESALIGTRVEDPAQQIEANRIVHSFDPCLACAVH 503
WP_014959255    434 LHYIKV-KDYKIKKYECVVPTTWNCSPKDDNDQPGALESALIGTRVENPDEQIEANRIVHSFDPCLACAVH 503 Desulfobacula toluolica
WP_013505084    446 AHWIETdGKGVIRNYEMVVPTTWNMSPRDGRGNPGAVEKMLEGTEVADAANPMELARIVRSTDPCIGCSVH 516 Desulfurispirillum in...
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