1L6W


Conserved Protein Domain Family
Transaldolase_FSA

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cd00956: Transaldolase_FSA 
Click on image for an interactive view with Cn3D
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.
Statistics
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PSSM-Id: 188643
Aligned: 38 rows
Threshold Bit Score: 212.821
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           #                    ##                                                     
1L6W_A        2 ELYLDTSDVVAVKALSriFPLAGVTTNPSIIAAGKk-pLDVVLPQLHEAMg--gQGRLFAQVMatTAEGMVNDALKLRSI 78  Escherichia coli
CAA55765      2 KIFLDTPDLSVVEQWLphGIVDGVTTNPTLLRKSGiedWTGTVGVLARRIa---PRDLSVQVSgvDHDDMVSQAKMLASR 78  Streptomyces lin...
ZP_00106799  18 AIYLDSAIASEAKVVKlwGWVKGITTNPTLLSQSDt-pPETTLKNLVALT----SGPLYYQLVasDKAGMLAEGRKAFEI 92  Nostoc punctifor...
NP_786813     2 ELLLDTVNLDTIKKYAdvISLAGVTSNPSIVKKERpidFYKHMREVRQIIg--kERTLHVQVVgqTAEAMLADAHMILEE 79  Lactobacillus pl...
NP_816899     2 EFMLDTINLEAIRKYQkiLPLAGVTSNPSIVKQAGkidFFAQMKEIKKTIg---QASLHVQVVgqTTEEMLEDAQTIVQQ 78  Enterococcus fae...
NP_895280     4 QLLLDSADPSKWEAWLptGLFAGITTNPTLLRRAQqpcQLDHLKSLAAAAerlgCLELHLQAWgkHAIELAECGAALAQL 83  Prochlorococcus ...
NP_901917     2 KIWLDTIDIDAIRKAQamGVLAGVTTNPSILATANr-dVEAVLSEILDAQ----TGPLAVQVVarGLDGMLAQARRIAAI 76  Chromobacterium ...
YP_008982     2 EIWLDTTNVKTIQKAVrvGILSGITTNPSLIAQAKk-dMESILEDLLHYQ----EGPVTVQVIsqETNDMLQQGQMLYSF 76  Parachlamydia sp...
ZP_00287566   2 EIMLDTANTKSIYSCQqfLNLTGVTTNPTILKKEGasnFFSHMKEIKKIIg---QIPIHIQTIgrTEEEMIEDARVIIEE 78  Enterococcus fae...
ZP_00328039   2 VLYLDSAIVTEARVASkfGWISGVTTNPTLLAKSDl-sPEATLKELSEII----SGELYYQLTatSFDEMIAEGKAASKL 76  Trichodesmium er...
Feature 1                #                                                 #                    
1L6W_A       79 Ia---DIVVKVPVTa----EGLAAIKMLKAEGIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGg-sGIQTVTDLH 150 Escherichia coli
CAA55765     79 Ge---NIVIKVPVIspdgrPHLDVMTTLREYGIPVNATACLSAGQALAAAKAGVRYASLLWGRVGDEGg-cPESVVADIT 154 Streptomyces lin...
ZP_00106799  93 Ig--sQTILKIPAT-----PLGFEVVASLSPEITCSVTAIYSAAQAAVAREAGAKIAIAYVNRATRLLg-dGIALVRDMA 164 Nostoc punctifor...
NP_786813    80 Ld--dQVYIKVPTDm----TGLAVIKQLKKEDIHVTATAIYSEFQGYLAIAAGVDYLAPYYNRMINMNi-dSDLVIKHLA 152 Lactobacillus pl...
NP_816899    79 Lg--qETFIKIPVNe----AGLAAIKQLKQANYRITATAIYTEFQGYLAIAAGADYLAPYYNRMENLTi-dSQKVIEHLA 151 Enterococcus fae...
NP_895280    84 TtpalTIHVKLPITq----AGSQAASTLIAAEIPITFTACFEAPQVLIAAALGAQHIAPYLGRINDQGrdgYTELIAMQR 159 Prochlorococcus ...
NP_901917    77 Sp---RMVVKIPAVg----DGFRAMSMLEREGVATLATAIFETRQLALAALAGASYAAPYVNRIELSAg-nAFEVLEQSQ 148 Chromobacterium ...
YP_008982    77 Sn---RIIVKVPLTk----NGLEALHLLARQGIPTMATVIFHPRQALMAALAGANYVAPYISRIEKLGe-nPWPMLESLT 148 Parachlamydia sp...
ZP_00287566  79 Lg--kDTFIKVPVNq----AGLQAIKKLKKEGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGi-dAMKVIDSLR 151 Enterococcus fae...
ZP_00328039  77 Ig--hKIVLKIPAT-----ATGFQATSHLSKNIDCSVTGIYHPAQALVAAETGAKYAIAYVNRATRLLg-dGLKLVREMA 148 Trichodesmium er...
Feature 1                     #                                                 
1L6W_A      151 QLLKMHapQAKVLAASFKTPRQALDCLLaGCESITLPLDVAQQMISY-PAVDAAVAKFEQDWQG 213 Escherichia coli
CAA55765    155 GLLRRHgmTAQLLVGSCMYPADITRGLTaGADAVTVPPALLARWLDH-HYARATVRDFQADAGV 217 Streptomyces lincolnensis
ZP_00106799 165 SVLKGS--DTEILAASIKSPEEAAASLQaGAHHLTLPLAMLQAIATH-EFSQKTVEEFAKGGIG 225 Nostoc punctiforme PCC 73102
NP_786813   153 NQIQREqsTTKILAASFHTVQQINASLVmGAQAVTLGPDLLETALNS-PAISAVVAGFKADWES 215 Lactobacillus plantarum WCFS1
NP_816899   152 AEIKRTnaKSKILAASFKNVAQINQACQmGAQAVTIAPELVTQGLAM-PAIQKAVTDFQEDWVA 214 Enterococcus faecalis V583
NP_895280   160 ALEGVGs-SCKLLVASLRSRRDLSHLAAaGIDTFTISAELAEELFEV-KATLDAAAAFEQDACS 221 Prochlorococcus marinus str. MIT...
NP_901917   149 RLLDAYgyKTAILAAAVKTVEQFLRCAQtGVAAVTLPVAVFQQLYASsEDIEESLRKFDAAWQS 212 Chromobacterium violaceum ATCC 1...
YP_008982   149 KTFQQYqlQTKIMGASLNSVDQVIKCAEiGIYGVTLKDDLFEKMIEDySPTVEGVHQFADEWEH 212 Parachlamydia sp. UWE25
ZP_00287566 152 TEIERTqrPTKILAASFKNCEQVTTAIRsGAHAITLGKELLDQVLEM-PSIDKAVRGFQEDWVQ 214 Enterococcus faecium
ZP_00328039 149 KVLEGS--STEILAASVKSPDEATETLLaGAHHLTLPFSVLQTITTH-ELSEQTFKEFNEKGRG 209 Trichodesmium erythraeum IMS101

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