Conserved Protein Domain Family
rmlD

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TIGR01214: rmlD 
dTDP-4-dehydrorhamnose reductase
This enzyme catalyzes the last of 4 steps in making dTDP-rhamnose, a precursor of LPS core antigen, O-antigen, etc. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Statistics
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PSSM-Id: 273505
Aligned: 9 rows
Threshold Bit Score: 381.747
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAF83071       2 TVLVFGAGGQIGQELLRSLS---GRVVCAvTR-----------SgrlpngrecvQADFDRPETLRPLLDAQRPAQVVNAA 67  Xylella fastidi...
WP_014407064   4 KILLLGSAGQVGRELAIPLSc-fGSVQEA-TR-----------A----------SFDLAQPDVLGEKIRAFAPDIIVNSA 60  Synechocystis s...
WP_010877394   2 KILITGSSGMLGSDLVDILS----RRHEVvTS-----------G----------SLDIRDLEGVMELLRETRPDAVVHAA 56  Methanothermoba...
WP_011713753   5 TVWITGAQGQMARALYQQTPp--GCAVRCfGR-----------Q----------QWDLSQPAKLELPRQN-LPQLLIHTA 60  Magnetococcus m...
WP_010884528   5 RIAIIGANGQLGTDLVEVFGndpEFEVVPlTH-----------K----------DLDVTIPESL-KVLKEIKPDVLINTA 62  Pyrococcus hori...
WP_010980837   2 RILLTGSKSQLARCLRDRLp--eDWETIAtDS-----------A----------SLDITDADAVCNMVKSFQPDAIVNTA 58  Neisseria menin...
WP_003112614   3 RILLLGANGQVGWELQRALAp-lGELLVCdRR----------------------RADLADPEGLARLVRAERPQFIVNAG 59  Pseudomonas aer...
WP_010866205   2 KLLVTGGTGLLGYNLVQQLLkkgYSVYPTyNKntpfklagarwS----------KVNLEDPSQLTQLFRDIKPDAVIHTA 71  Aeropyrum pernix
WP_031711309   7 RLVITGAGGQLGSHLTAQAAr-eGRDMLAlTS-----------S----------QWDITDPAAAERIIRHG--DVVINCA 62  Mycobacterium t...
AAF83071      68 AYTAVDRAESEPDVVFRINAQAPGVIAHWCARHGVPLVHYSTDYVFDG----QGTSPYGVDDPVAPLNIYGASKLAGERA 143 Xylella fastidi...
WP_014407064  61 AYTAVDRAETEPELAYAVNALAPQAIAKVAKEIGAYVVHISTDYVFDG----SQSSPYRETDATNPLGVYGQSKFQGEIA 136 Synechocystis s...
WP_010877394  57 AFTDVDCAETERDKAYQVNVLGTRNIAAAASAVGSSILYISTDYVFDG----EKGDGYLEFDEPNPLNFYGKTKYLGEVS 132 Methanothermoba...
WP_011713753  61 AMTDVDGAEKDPHLAFALNGTATERLAQWCADYGIAMLALSTDYLFDG----QATRPYRPDDRVNPLSVYGRSKQVGEQA 136 Magnetococcus m...
WP_010884528  63 AYVRVDDAELYPEKAFAVNAIGALNVARIANEIDAVNVYISTDYVFDG----EKGEPYTEEDVPNPINVYGVSKYTGEIF 138 Pyrococcus hori...
WP_010980837  59 AYTAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFIHISTDYVFDG----KGKRPYQESDFTNPSNVYGQSKTAGELL 134 Neisseria menin...
WP_003112614  60 AYTAVDKAESDADNARLINARAVAVLAEEAAACGAWLVHYSTDYVFDG----AGSVPFAEDAPTGPLSVYGQTKLEGEQA 135 Pseudomonas aer...
WP_010866205  72 AYTDVDGCELHRERAYRINFLASMTVARLAARHGSLLIYVSTDYVFDG-----DKGMYREEEAPNPINYYGLSKLLGEVA 146 Aeropyrum pernix
WP_031711309  63 AYTDVDGAESNEAVAYAVNATGPQHLARACARVGARLIHVSTDYVFDGdfggAEPRPYEPTDETAPQGVYARSKLAGEQA 142 Mycobacterium t...
AAF83071     144 VRAA-GG--CSLILRTSWVY----AAH--G-HNFLRTMLRLGATS-ERLPVVADQIGTPTAAGLIADVTAQLLAGgg--- 209 Xylella fastidi...
WP_014407064 137 IADS-GC--NFLIVRTAWVY----GVH--GsGNFVKTMVRLGKER-QKVRVVADQIGGPTWAKDLAEAIAALTEQ----- 201 Synechocystis s...
WP_010877394 133 VRQL-SE--RFYIVRTSWLF----GRN--G-RNFVGTMVELAERG-HEISVVDDQYGSPTYTRDLAAAIGNLLER----- 196 Methanothermoba...
WP_011713753 137 IQEIlGD--QAAIIRTAWLY----DGG--SgRNFLTTMLRLMGQGtTPLRIVEDQWGAPTACDALARVVWALAQQlld-- 206 Magnetococcus m...
WP_010884528 139 TRNY-SP--KHYIIRVASLYgkagASG--KgGNFVEWVIEKAKHG-EELKIVDDQFMSPTYTKDVARTLKEFLKLr---- 208 Pyrococcus hori...
WP_010980837 135 ALSA-NP--DSLILRTSWLF----SEY--G-DNFIRTMLNLARER-SPLSAVHNQIGCPTYAGDLSATIIRLLQHs---- 199 Neisseria menin...
WP_003112614 136 IRAS-GC--RHLIFRTSWVY----AAR--G-GNFAKTMLRLAGQR-DELKVVADQFGAPTSAELIADVTAQALQRlcwdv 204 Pseudomonas aer...
WP_010866205 147 TLSA-MDkeNVLVVRVSGLY----GYSptGkRNFGINVLEKLLRG-EEVRAFYDQYLSPTYTYFLSRRLIDVLERe---- 216 Aeropyrum pernix
WP_031711309 143 VLAA-FP--EAAVVRTAWVY----TGG--TgKDFVAVMRRLAAGH-GRVDVVDDQTGSPTYVAD-LAEALLALADa---- 207 Mycobacterium t...
AAF83071     210 --qsRHAGIWHLTATGQTSWHGFAEEIFAQAQACGLMMR--VPQVQAIASVGYPTAARRPAYSCLDTTALVETFGI--VL 283 Xylella fastidi...
WP_014407064 202 ----RAQGIYHYSNSGVASWYDFAVAIFEEVENLGIPLK--VRQVVPIATAAYPTPARRPAYSVLSHQKIVETLGS--AP 273 Synechocystis s...
WP_010877394 197 ----PAYGVYHLTNSGQCSWYEFAIDIFNELGMEVC--------LKPVKSHEFPRPARRPSFSVLRNYNWSMEGFK--PL 262 Methanothermoba...
WP_011713753 207 --qaHGGGLYHWSCQGQSSWFEFAQTIQQIALEMGLLQH--PVELQPISAVQYGAPAPRPAYSVLDSTLLVQRLGTvaQP 282 Magnetococcus m...
WP_010884528 209 ---sE-FGVYHMVNEGFCSWYEFTEAIFDVLGWNV--------EIKPIKSNELNRLAKRPRFSALKNEKLEKIGLR---M 273 Pyrococcus hori...
WP_010980837 200 ---nPVRGIYHYAGSKSVSWYEFAQHIFQAASQQQTSFP--VPELTAVSDKEYPTAAPRPAYSILDCRKIENDFGI--KP 272 Neisseria menin...
WP_003112614 205 elaaRASGTYHLVASGETSWHLYARFVIEQALERGWELQatPQRVLPIATEDYPVPAKRPANSRLDNRKLQQVFGL--VL 282 Pseudomonas aer...
WP_010866205 217 -----IRGVLHLAGER-LSRLEFAQLIAKVLGADAEL-------IKPISMKEANLPARRPRDSSLDTTMAKK-LGL--EL 280 Aeropyrum pernix
WP_031711309 208 ---gVRGRVLHAANEGVVSRFGQARAVFEECGA-----D--PQRVRPVSSAQFPRPAPRSSYSALSSRQWALAGLT--PL 275 Mycobacterium t...
AAF83071     284 PDWRQGVRGVLDDI 297 Xylella fastidiosa 9a5c
WP_014407064 274 PHWRASLRAMLHQA 287 Synechocystis sp. PCC 6803
WP_010877394 263 RNYRDALRDYLKDA 276 Methanothermobacter thermautotrophicus
WP_011713753 283 PPWQQALRAVMQAM 296 Magnetococcus marinus
WP_010884528 274 RHWREALEEYLKEK 287 Pyrococcus horikoshii
WP_010980837 273 SDWQKALHRSFPSC 286 Neisseria meningitidis
WP_003112614 283 PDWRYHAGRMIQEL 296 Pseudomonas aeruginosa
WP_010866205 281 PSQEESVKHFVNIY 294 Aeropyrum pernix
WP_031711309 276 RHWRSALATALAVP 289 Mycobacterium tuberculosis
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