Conserved Protein Domain Family
Bthiol_YpdA

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TIGR04018: Bthiol_YpdA 
putative bacillithiol system oxidoreductase, YpdA family
Members of this protein family, including YpdA from Bacillus subtilis, are apparent oxidoreductases present only in species with an active bacillithiol system. They have been suggested actually to be thiol disulfide oxidoreductases (TDOR), although the evidence is incomplete. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 188533
Aligned: 30 rows
Threshold Bit Score: 479.369
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDP82324       5 KVIIIGAGPCGLSAAIECEKAGFDVTVIERGNIVHALYRYPTHQQFFSTSEKLAIGDIPFYSTERKPKRNEALVYYRKVV 84  Bacillus seleni...
EEN97071       5 KIIIVGGGPCGLAAAIALQDAGFSPLVIEKGNIVHSIYRFPTHQTFFSTSDRLEIGGVPFITENQKPTRNQALAYYREVV 84  Geobacillus sp....
EDV74804       3 DVLIIGAGPCGLAAAIECGRQGLSCEIIDKHNVVHSIYLYPTHMQFFSTAEMLEIGEVPFAISNDKPYRHEALAYYRRVA 82  Geobacillus sp....
EDS49103       5 EAIIIGAGPCGLAAAIELERIGLHPVIIEKSNIAHSISMYPTYMHFFSTPERLEIGEIPFTTPNDKPSRLEAINYYRTAA 84  Paenibacillus s...
EED07228       3 EACIIGAGPCGLAVSVELKRRGIPHVVIEKSCIVSTIYRFPTQMVFNSTPERLEIGDIPFYTERAKPTRMEALTYYRAVV 82  Alicyclobacillu...
WP_012282594   3 DIAVIGGGPCGLACAIEAKEHGLDCVVLEKGNVVRSVAEYPVYMVLFSTTDMLEIGGLPFISGNCRPTRLETVRYYWRAV 82  Heliobacterium ...
WP_011173282   3 DVLVVGAGPVGLCAALWAKRLGLSHLVLERGTVAETVYRFPRDMVFFSEAKNIEIGGHPLVAQGPKPTRKEALLYYQRVA 82  Thermus thermop...
WP_012686284   3 DVLIVGGGPCGLAAAIACKRAGLDPIIIEKGSLVHSIYRYPTYMIFHSTPDLLEIGGVPFATANDKPTRQEALNYYRLVA 82  Brevibacillus b...
WP_011066207   5 DVIIIGAGPCGMATALELQKNGIEPLLIEKGNVAQTISNYPTHQTFFSSSDKLEIGDVPFITENKKPVRNQAMVYYREVA 84  Oceanobacillus ...
WP_011275727   5 ESIIIGGGPCGLSAAIEQKRKGIDTLVIEKGNVVDAIYKYPTHQTFFSSSDKLSIGDIPFIVEESKPRRNQALVYYREVV 84  Staphylococcus ...
EDP82324      85 EEYGLTIEAYEEVTKIDRLG--IhDFKVTSvkqngLTM-ERDAHAVIVATGYYDSPNYMHIPGEDQKHVFHYFHEAHPFY 161 Bacillus seleni...
EEN97071      85 VRKQVRVNTFEEVKAVKPQEd-G-AFLIET-----TKG-TYRAQYVVIATGYYDHPNYMNVPGEELPKVMHYFKEAHPYF 156 Geobacillus sp....
EDV74804      83 KHFNLNISPYEEALTIAKQPd-G-SFQVKTrrrggEET-LRQAKHVVIATGYFDHPNYIGIPGEDLEKVTHYFREAHPYA 159 Geobacillus sp....
EDS49103      85 LRNSLRVNAYETVLRIERQDn-G-LFHLTSadrygEEK-QYEARYVVVATGYFDHPNYLGIPGEEMDKVTHFFREAHPYT 161 Paenibacillus s...
EED07228      83 RRLELPVRQYEEVIGVERDDrnG-GFRVHSrtlsgRTL-ETEARSVVVATGYFDHPNMLGVPGENLPHVTHYYRDAHPYY 160 Alicyclobacillu...
WP_012282594  83 QHFGIPIQTYREVTEVLPTS--S-GFMLHTrdklnGEEpVVFAKRVVVATGCYDRPNLIGVPGEELPHVSHYYKEPFPYM 159 Heliobacterium ...
WP_011173282  83 EREGLNVLTYTEVLSIRGRE--G-AFQVLAkdrkgER--AFSARYVVVATGYFGNPNRLGVPGEDLPHVLHRYEEAAPFF 157 Thermus thermop...
WP_012686284  83 AREKLRVNVYETVTEAKKTP--E-GFQITTtdrftKTH-TYEAKNLVIATGYFDNPNRLQVPGEELPKVSSFYKEAHPYT 158 Brevibacillus b...
WP_011066207  85 QRKELRIRPYEEVIGLVKNKn-GkGYTITTsnihkEQN-VYYAAYVILATGYYDQPNYLEVPGESKPKVTHYFKEAHPYF 162 Oceanobacillus ...
WP_011275727  85 KHHQLNVRAFEEVLTVKKID--N-KFTITT-----TKD-VYECKFLTVATGYYGQHNKLEVKGAELPKVQHYFKEAHPFF 155 Staphylococcus ...
EDP82324     162 NQKVAVIGGKNSAIDAALELEKAGAEVSVYCRYDNYSSSIKPWILPDFESLVKQGKIMMHFETEIHEIGEDTISVSDv-T 240 Bacillus seleni...
EEN97071     157 NTDCVVIGGKNSSVDAAMELVKAGARVTVLYRGNEYSKSIKPWILPEFDSLVKKGVIRMEFRAHVKAITEDAVVYEV--D 234 Geobacillus sp....
EDV74804     160 GMKTAIIGGSNSAVDAAMELIRVGAEVTMVYRGEEVSQNIKPWVRPLFDSMVQKGHIQLHLNSRVVQIAESSITVLSn-Q 238 Geobacillus sp....
EDS49103     162 GMEVAIIGGSNSAIDAALELERVGAKVTVIYRGAGYSSSIKPWVRPGFEAKVNNGIIRMLFESRVVEIDKRHVIVESp-E 240 Paenibacillus s...
EED07228     161 GQRVVIIGGTNSAAEAAIDLHRVGASVTLVHRGAAMSDKIKPWVKPDIQSLIDKRAIDFHFRSRVTEICADHVRVETp-D 239 Alicyclobacillu...
WP_012282594 160 GRRVIIVGGGNSAAEAALELSRFGALTTVVHFRGEMDATVKPWIGAELTARILKNEIAALFHTRILSIRPQTITLSTtgD 239 Heliobacterium ...
WP_011173282 158 GREVAVVGGSNSAVEAALDLYRGGAKVTLVHRGKWVRPSVKYWLLPDFENRVKEGSIRAVMEARVEAITPEGLWLSRp-S 236 Thermus thermop...
WP_012686284 159 GMKVAVVGGNNSAVDAAMELERAGAEVTVICRRTELSDKVKAWTRPVFESLIKKGRIHMLFGATVESIEERSIRVRM--G 236 Brevibacillus b...
WP_011066207 163 NQNVVVIGGKNSSVDATIELHKAGAHVTVLYRGSNYSKSIKPWILPEFESLVRNGKVNMVFESTVKEINDHSLTYES--Q 240 Oceanobacillus ...
WP_011275727 156 NLDVTVIGGKNSAVDAALELEKAGANVTVLYRGDRYSAAIKPWILPNFESLVNHEKITMEFNANVTEITENSVIYEK--N 233 Staphylococcus ...
EDP82324     241 GTKRNDRADFVFAMTGYHPDHSFIRSMGVEVDMET--GRPVFNSESMETNVDGIYIAGVIAAGNNANEIFIENGRHHGGL 318 Bacillus seleni...
EEN97071     235 GETKTIKNDFVFAMTGYRPDHRFLMNIGVQIDPES--GRPHYDPETMETNVPGVFIAGVIAAGNDANEIFIENGRFHGDA 312 Geobacillus sp....
EDV74804     239 GQESIIENDFVLALTGFRPDRKLLASSGVQLDEDM--EKPLYNPDTMETNVPGLYVAGVIASGRNANEVFIETGRLHGRL 316 Geobacillus sp....
EDS49103     241 GRH-PVANDFVLALTGFHPDRDFLTSSGVRIEEE---GFPYFDETTMETNVPGLYLAGVVASKHEANEIFIESGRFHGNK 316 Paenibacillus s...
EED07228     240 GPL-DIPCDHVLALTGYHPDTSFLEKLGIRIEPDT--GIPAHDETTYETNVPGIYVAGVVVSGFDANRIFIENGRLQAPR 316 Alicyclobacillu...
WP_012282594 240 ETPFELEADFVFLMTGYRPNTDLLVQAGAALDAS---GFPVHNPLTMETTVPGLYVAGAISEGWRVTQANIEKGRFHGKR 316 Heliobacterium ...
WP_011173282 237 GRE-FLPADFVVVLIGYRAEDRLLREAGVAYEGER----PWLSPE-WETSVPGLFAVGSCAYGPDTRSVFIENGREHARA 310 Thermus thermop...
WP_012686284 237 DEVITLANDHVFSLIGYRPDRTFLHSLGVMIDEET--GIPAHHPETMETNIPGLYIAGVIAAGRHANAIFIENGRFHGEG 314 Brevibacillus b...
WP_011066207 241 GESYTIDNDFVFAMTGYQPNYSLLRQAGVEIIKET--GKPQFDKETLETNVDDLYIAGVIAAGYDNNKVFIENGRFHGKP 318 Oceanobacillus ...
WP_011275727 234 GKVTEIPNDHVFAMIGYHPDYDFLESIGIEINTNEygTAPVHNKETFETNVENCYIAGVIAAGNDNNAIFIENGKYHGGI 313 Staphylococcus ...
EDP82324     319 IASHLGAQ 326 Bacillus selenitireducens MLS10
EEN97071     313 IAACIAKR 320 Geobacillus sp. Y412MC52
EDV74804     317 IAEHLGTK 324 Geobacillus sp. Y412MC10
EDS49103     317 IAEHIVSL 324 Paenibacillus sp. JDR-2
EED07228     317 IADAIASR 324 Alicyclobacillus acidocaldarius LAA1
WP_012282594 317 IIQSIDTD 324 Heliobacterium modesticaldum
WP_011173282 311 ALTAIAAR 318 Thermus thermophilus
WP_012686284 315 IARHIASH 322 Brevibacillus brevis
WP_011066207 319 IAESILRK 326 Oceanobacillus iheyensis
WP_011275727 314 ITQSILSK 321 Staphylococcus haemolyticus
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