Conserved Protein Domain Family
uvrC

?
PRK00558: uvrC 
excinuclease ABC subunit UvrC
Statistics
?
PSSM-Id: 234792
Aligned: 822 rows
Threshold Bit Score: 415.286
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
219683848  13 RDLFRPKTGDIPAQPGVYKWRDGDGQVIYVGKAKNLRNRLSNYFQPLRqlhpRTQTMVLTARSLEWTVVGTELEALTLEY 92 
125975219   1 MFDIQEELKKLPDKPGVYIMKDENGEIIYVGKAVVLKNRVRQYFQSLSnqtpKVRAMVAHIKEFEYIVTDTELEALILEC 80 
146296208   1 MLTLQEKLANLPTTPGVYMMKDENGKVIYVGKAVNLRNRVRQYFQNSDmt-pKTRLMVKKIKDFEYIVTDTEVEALILEC 79 
167039707   1 -MTIEEKLKLLPEKPGVYIMKDKSGKIIYVGKAVVLKNRVRQYFQNKEkqlpKVKVMLSHVEDFEYIVTDTELEALMLEC 79 
167036996   1 -MTIEEKLKLLPEKPGVYIMKDKSGKIIYVGKAVVLKNRVRQYFQNKEkqlpKVKVMLSHVEDFEYIVTDTELEALMLEC 79 
220928256   1 MFDIQEELKKLPDKSGVYIMKDANGVVIYVGKAVVLKNRVRQYFQQSAnhppKVQAMVSKVSEFEYIVVDSEVEALMLEC 80 
222528390   1 -MLLEEKLSNLPTSPGVYIMKDENGNVIYVGKAVNLRNRVRQYFQNSQdmpsKTRLMVRKIKDLDYIVTDNEVEALILEC 79 
289578945   1 -MTIEEKLKLLPEKPGVYIMKDKKGEIIYVGKAIVLKNRVRQYFQNKEnqlpKVKVMLSHVSDFEYIVTDTELEALMLEC 79 
297545157   1 -MTIEEKLKLLPEKPGVYIMKDKKGEIIYVGKAIVLKNRVRQYFQNKEnqlpKVKVMLSHVSDFEYIVTDTELEALMLEC 79 
304316131   1 MVNIEEKLKLLPEKPGVYIMKDSSGKIIYVGKAVILKNRVRQYFQNPAnqipKVRTMVRHIADFEYIVTDTELEALILEC 80 
219683848  93 TWIKEFDPRFNVQFRDDKTYPYLALSIGEEYPRIWVTRS-RKrRDTRYYGPYAKVWDLRKSLDGLLRTFPVRTC---TDA 168
125975219  81 NLIKKHRPKFNILLKDDKNYPYIKVTMNEDFPRILMTRRvEK-DGAKYFGPYTSAYAVRETIDLVKKLFPVKTCskvLPR 159
146296208  80 NLIKEYRPKYNVLLRDDKNYQYIKI-TNEMFPRLVTTRKvEK-DGAKYFGPYVSGYSVKQTIELLKSLFMLRTC----KR 153
167039707  80 NLIKKYKPKYNVLLKDDKNYPYIKVTVNEEYPRIMFTRRiEP-DGAKYFGPYSSAFAVRETIKLVRKMFPIRTCnknIEK 158
167036996  80 NLIKKYKPKYNVLLKDDKNYPYIKVTVNEEYPRIMFTRRiEP-DGAKYFGPYSSAFAVRETIKLVRKMFPIRTCn-kNIE 157
220928256  81 TLIKKYKPKYNILLKDDKHYPYIKVTLNEEYPRILKTRRvEK-DGARYFGPYSSGFAVNDTIDTLKKLFSLKTCnknLPR 159
222528390  80 NLIKEYRPKYNVLLRDDKNYQYIKI-TNEMFPRLVTTRKvEK-DGSRYFGPYVSGYSVKQTVELLKSLFMLRTC----KK 153
289578945  80 NLIKKYKPRYNVLLKDDKNYPYIKVTVNEEYPRIMFTRRiEP-DGAKYFGPYSSAFAVRETIKLVRKMFPIRTCnrnIEK 158
297545157  80 NLIKKYKPRYNVLLKDDKNYPYIKVTVNEEYPRIMFTRRiEP-DGAKYFGPYSSAFAVRETIKLVRKMFPIRTCn-rNIE 157
304316131  81 NLIKKHKPKYNILLKDDKNYPYIKITVNEDYPRILFTRRlEM-DGAKYFGPYSSAFAVRETIKLLRHMFPLRSCnrnIEK 159
219683848 169 NFRKaqlTNRPCLLASIGKCSAPCVGRITPQDHKRLCEQLVGVLTGGIGKsYVAKLTAAMKEASAELDFEKAARLRDEIQ 248
125975219 160 D-IG---KGRPCLNYHIYQCLGPCQGNVSKEEYRFMMQDVCNFLGGRQED-IIKKLEKDMKEAADNLEFERAARIRDKIN 234
146296208 154 KFPDqlgKGRPCLNFYIERCLGVCKGDIPEEEYQKLVEKAVKVLSGKGDE-IVEELKKKMFEYADNLMFEKAQEIKNKIT 232
167039707 159 D-MG---KVRECLYYHIGLCSAPCTNKINKEDYIKLVDQAVLFLDGKRDW-LIQKLKEDMKKAAEELRFEEAARIRDQIF 233
167036996 158 KDMG---KVRECLYYHIGLCSAPCTNKINKEDYIKLVDQAVLFLDGKRDW-LIQKLKEDMKKAAEELRFEEAARIRDQIF 233
220928256 160 D-IG---KTRPCLNYHMKQCLAPCQGGVNRDEYREMMKKICRFLGGQYDE-IINDLRIQMETAAEQLDFEKAAQLRNKIT 234
222528390 154 KFPDqlgKGRPCLNFHIEKCLGVCKGDVSEEEYQKLVERAVKVLSGKGDE-IVEELKAKMFEYAENLMFEKAQEIKNKLS 232
289578945 159 D-MR---KVRECLYYHIGLCSAPCTNKINKEDYRKLVDQAVLFLDGKRDW-LVQKLKEDMQKAAEELRFEEAARIRDQIF 233
297545157 158 KDMR---KVRACLYYHIGLCSAPCTNKINKEDYRKLVDQAVLFLDGKRDW-LVQKLKEDMQKAAEELRFEEAARIRDQIF 233
304316131 160 D-IG---KCRECLYYHIGLCSAPCIGQISKDDYMKLVDDALMFLEGKHDV-LLKKLKEEMEKASQNMEFEKAAKLRDQIY 234
219683848 249 MLSTVVEQNAVvLdQD-VDADVFGIASDELEASVHAFFVRSGSIRGERNWSVEriedvddaeLISDLIMQVYSELYsere 327
125975219 235 SLKHIAEKQKI-IsTAmEDQDVIAFAKSETDSCIQVFFIRGGKLIGREHFILEgtsdvsdseLMTAFVKQFYSSAAy--- 310
146296208 233 SLEQIITKQKViY-ADdRSEDVINYAEDSSNICIVVLVIRNGKLINKEEFVLKnd-----eeVFERFLEQYYSDVVs--- 303
167039707 234 AIERTSEKQKV-VsVGeDEQDIISMARSADISCIQVFFVRDGKLSGREHYYMKntegmergeIISSFIKQFYEGAPy--- 309
167036996 234 AIERTSEKQKVvSvGEd-EQDIISMARSADISCIQVFFVRDGKLSGREHYYMKntegmergeIISSFIKQFYEGAPy--- 309
220928256 235 SIKQLSESQKV-LfTDlEDRDIIGYSADSTDLCIQVFFVRNGRVIGREHFIFEgeanedkgySLSTFIKQFYTKVQy--- 310
222528390 233 SLEQIITKQKViY-ADdRSEDVINFAKDQTHIAIVVLIIRNGKLINKEEFVLKae-----edTFERFLEQYYADVLs--- 303
289578945 234 AIESTSEKQKV-VsVGeDEQDIISIARGAGISCIQVFFVRDGKLSGREHYYMKntegmergeIISSFIKQFYEGAPy--- 309
297545157 234 AIESTSEKQKVvSvGEd-EQDIISIARGAGISCIQVFFVRDGKLSGREHYYMKntegmergeIISSFIKQFYEGAPy--- 309
304316131 235 GIEKTSEKQKI-IsTSgEDQDVISMARSADDACIQVFFIRGGKVSGREHYFMKntdemnrsdIMSSFIKQFYDGAPy--- 310
219683848 328 agefrrtdappssrptveppiaqaatldaavsaeptpirmekaqikveeqrtamgstqrmsagdassraqstkarnarre 407
125975219     --------------------------------------------------------------------------------    
146296208     --------------------------------------------------------------------------------    
167039707     --------------------------------------------------------------------------------    
167036996     --------------------------------------------------------------------------------    
220928256     --------------------------------------------------------------------------------    
222528390     --------------------------------------------------------------------------------    
289578945     --------------------------------------------------------------------------------    
297545157     --------------------------------------------------------------------------------    
304316131     --------------------------------------------------------------------------------    
219683848 408 htgradllepiapVPRQVLVS-VMParaD-D------LEQ------YlrRlrggA---VSIGTPARGNKRQLLERAEQNA 470
125975219 311 -------------VPGQIILQeDID---E-Me-----IIEkw--lsG--K----RgtkTYIKVPRRGEKLKLVEMVSKNA 360
146296208 304 -------------VPKEIILPhEVG-----NgeniekMIEkly------------gfkAKIVVPKQGEKKQLLEMAKKNA 353
167039707 310 -------------IPKEIITDvELD---E-Se-----LLSew--lsQ--K----RgnkVFITIPVRGKKKELVDMVYQNA 359
167036996 310 -------------IPKEIITDvELD---EsEl-----LSEwlsqkrG--N----K---VFITIPVRGKKKELVDMVYQNA 359
220928256 311 -------------VPSEIVLQsEVD---D-Se-----TIAkw--ltE--K----RgfkVALRVPQRGDLVKLVHMVSENA 360
222528390 304 -------------LPKEIIIPhEIE-----NfdniekMIEkly------------gfkVKVIIPKQGEKKQLLDMAKKNA 353
289578945 310 -------------IPKEIITDvELD---E-Re-----LLSew--lsQ--K----RgnkVFITIPMRGKKKELVDMVYQNA 359
297545157 310 -------------IPKEIITDvELD---ErEl-----LSEwlsqkrG--N----K---VFITIPMRGKKKELVDMVYQNA 359
304316131 311 -------------IPKEIITDvDMD---E-Kh-----VLAew--lsN--K----RgnkVVISIPSKGKKKELVDMVYENA 360
219683848 471 qqalqrskmsrISDISARTTAMNDVADALGLSQAPLRIECYDISNtVGGAFQVASMVVFEDGMARKSEYRRFAIRG-ADG 549
125975219 361 lielnqfkeriKKEAALAKEGMEKLKELLNLDRLPRRIEAYDISN-TGSTEIVGSMVVFENGSPKKSDYRRFKIKSiNVQ 439
146296208 354 eisl----vnkQRIENYYIEALLHLKNLLGIEHDIEKIESYDISN-LAGADNVGTLVVFEDGKFNKDLYRKFKLKSfEGQ 428
167039707 360 lealk--ndisIREEISKDQVVLELSNLVGLD-YAKRIEAYDISN-TRGQDNVGSMVVFVDGKPKKSQYRKFNIKYvEGQ 435
167036996 360 lealk--ndisIREEISKAQVVLELSNLVGLD-YAKRIEAYDISN-TRGQDNVGSMVVFVDGKPKKSQYRKFNIKYvEGQ 435
220928256 361 eitlklhrerqSREGTVHSEGMAQLVKLLGLEEAPARIESYDISN-TGSSEIVASMVVFENGRPARQEYRKFKMKSiEQQ 439
222528390 354 eisl----anrQRVDDVYAEALLTLKSILGLENEIEKIESYDISN-IAGADNVGTLVVFEDGRFNKEFYRKFKIKGfEGQ 428
289578945 360 lealk--ndisIREEISKDQAVLELSKLVGLD-YARRIEAYDISN-TRGQDNVGAMVVFVDGKPKKSQYRKFNVKYvEGQ 435
297545157 360 lealk--ndisIREEISKDQAVLELSNLVGLD-YARRIEAYDISN-TRGQDNVGAMVVFVDGKPKKSQYRKFNVKYvEGQ 435
304316131 361 leslk--sdinLKMKRQKSDAVSELSKLLGLE-YAERIEAFDISN-IRGTDNVASMVVFVDGKPHKSSYRKFNIKTvEGQ 436
219683848 550 kgavDDLNALYETLTRRfkhgniagdtgesmdnekrasqegelesaeqvqqeivqqntdrrhfaY--------------- 614
125975219 440 ----NDYQSMQEVIFRR-----------------------------------------------Lkraqkemtekdeggg 468
146296208 429 ----DDIRSVKEVLTRR-----------------------------------------------Ftnle----------- 446
167039707 436 ----DDYESMREVIERR-----------------------------------------------Flhaieekeliek--- 461
167036996 436 ----DDYESMREVIERR-----------------------------------------------Flhaieekeliek--- 461
220928256 440 ----NDYGSMQETLFRR-----------------------------------------------Lnrakrekee------ 462
222528390 429 ----DDIRSVKEVLTRR-----------------------------------------------Ftnle----------- 446
289578945 436 ----DDYESMREVIERR-----------------------------------------------Flhgieekeliek--- 461
297545157 436 ----DDYESMREVIERR-----------------------------------------------Flhgieekeliek--- 461
304316131 437 ----DDYGSMREVILRR-----------------------------------------------Ikhgieerklidd--- 462
219683848 615 ------------KPNLVVVDGGKPQVMAAAKALEDCGVtDVAVCGLAKRM----EEVWVpdDDYPVILKRSSEGMYLLQR 678
125975219 469 kdvgekgagfgtLPDVLLVDGGTGHVNAVRSVLEELDFn-IPVYGMVKDDnhrtRGLVT--GErEFDLSKDIVLLRFVTA 545
146296208 447 --------khgrLPDLILIDGGQNQVNAAVEVLRSLGF-NIPVAGMVKDDrhktRDLIY--KGqELNIQRDSLVFKLIST 515
167039707 462 geleedkakfaeMPDLIFVDGGIGHVNAVLQVLSGLGIs-IPVYGMVKDSkhrtRGLVS--PQgEIDIPMTTKAFRLIAQ 538
167036996 462 geleedkakfaeMPDLIFVDGGIGHVNAVLQVLSGLGI-SIPVYGMVKDSkhrtRGLVS--PQGEIDIPMTSKAFRLIAQ 538
220928256 463 ---gtenakfskLPDLILVDGGSNHVNAARQVVEELGYn-FKIAGMAKDDrhrtKSLVY--MGnEYELATNMPLLRFITE 536
222528390 447 --------khgrIPDLILIDGGQNQVNAALEVLNTLGF-FIPVAGMVKDDrhktRDLIY--NGkEAGIQEYPLVYKLIYA 515
289578945 462 geleenkakfaeMPDLILIDGGIGHVNAVLQVLYGLGIa-IPVYGMVKDSkhrtRGLVS--PQgEIDIPMTTKAFRLIAQ 538
297545157 462 geleenkakfaeMPDLILIDGGIGHVNAVLQVLYGLGI-AIPVYGMVKDSkhrtRGLVS--PQGEIDIPMTTKAFRLIAQ 538
304316131 463 gelqedkakfhiMPDLILVDGGLGHVNTAKEVLRELNVd-IPVYGMVKDSkhrtRGLVS--TDgEIDMPMTGRAFRLVAE 539
219683848 679 VRDESHRFAINYHRQTRRKGALRSALDEIPGIGPTFQKRLLNHFGSVRRMRQASLEELESVKGVGHAKARAIYEALHDN 757
125975219 546 IQDEAHRFALEYNRKLRAKRYSGSVLDNIEGVGPKRKKELIRHFGSVKAIKEAEPGEIAKVKGISRDLAQKIYDYFRQQ 624
146296208 516 IQEETHRFAVKYHRELRKKHLYESILDEIEGIGEKRKIKLFRIFGSIDNLRKASIEEIVKAADIPYDIALKIKEKIGI- 593
167039707 539 IQEEAHRFAITFHKEKQSKRF-KSELLNIPGIGKKRAKALYDAFKSIEEIKRASVEDLKKVEGMNEKAAQAVYEYFRK- 615
167036996 539 IQEEAHRFAITFHKEKQSKR-FKSELLNIPGIGEKRAKALYDAFKSIEEIKRASVEDLKKVEGMNEKAAQAVYEYFRK- 615
220928256 537 IQDETHRVAVEYNRKLREKRYVRSELDEIEGIGQTRKKALIKHFKSVAAIRKADIAQLQEVNGISEKIAKNIYEYFN-- 613
222528390 516 IQEETHRFAVKFHREVRKKHLYESILDEIEGIGEKRKLKLFRTFGSIDNLRKASIEEIVKAADIPYEVALKIKEKIGV- 593
289578945 539 IQEEAHRFAITFHKEKQSKRF-KSELLNIPGIGEKRAKALYDAFNSIEEIKRASVEDLKKVEGMNEKAAQAVYEYFRK- 615
297545157 539 IQEEAHRFAITFHKEKQSKR-FKSELLNIPGIGEKRAKALYDAFNSIEEIKRASVEDLKKVKGMNEKAAQAVYEYFRK- 615
304316131 540 IQDEAHRFAITFHKETKSKKL-RSDLLNIPGIGEKRMKALFEAFKTIDDIKNATVEELKKVEGMNEKAANAVYDYFRSD 617
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap