Conserved Protein Domain Family
Glyco_transf_56

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pfam07429: Glyco_transf_56 
4-alpha-L-fucosyltransferase glycosyl transferase group 56
This family contains the bacterial enzyme 4-alpha-L-fucosyltransferase (Fuc4NAc transferase) (EC 2.4.1.-) (approximately 360 residues long). This catalyzes the synthesis of Fuc4NAc-ManNAcA-GlcNAc-PP-Und (lipid III) as part of the biosynthetic pathway of enterobacterial common antigen (ECA), a polysaccharide comprised of the trisaccharide repeat unit Fuc4NAc-ManNAcA-GlcNAc.
Statistics
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PSSM-Id: 429459
Aligned: 12 rows
Threshold Bit Score: 589.691
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCH:MU9_246       1 MTTLIHVLGSDIPHHNQTVLRFFNDVLAPQlpREEMPEFMVVSTAGQLLAQYPNLELDVWPDKKSLANAVTAKAKRDRQC 80 
WP_002444169      1 MTKLLHILGSDIPHHNQTVLRFFNDKLAAE--TTLAHRFMVVAGAGFTPEAYPALDITVYPGKSALAKALVAFARQHPDD 78  Shimwellia b...
wugsc:KPN_04293   1 MTALIHVLGSDIPHHNQTVLRFFNDELAA---DPQARRFMIVGDEASVRDGYPALDITCYPGKKALAQAVIATAKANRQQ 77 
P56258            1 MTVLIHVLGSDIPHHNRTVLRFFNDALAAT--SEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQ 78  Escherichia ...
KFD00376          1 MTTLIHVLGSDIPHHNVTVLRFFNDVLAECapEKLIYHFMVAAADASAFAEFTRLDIRVYPDKKSLADAVISRA-QDRTH 79 
Q7MYM4            1 MTTLIHVLGSDIPHHNRTVLRFFNDVLVQEigFLAKPKFMVVTKNRALLDDCPALDMAFFDSKKSLAQAVIAQACSDRDC 80  Photorhabdus...
BAN96834          1 ------MLGSDIPHHNHTLLRFFNDVMSVEspADAPRQFMVVSAAPDTLLAYPQLQIDVYPSKRALAQAVIARA-ADRRQ 73 
Q6CZF0            1 MTTLIHVLGSDIPHHNQTVLRFFNDVLATElpEHQIRHFIVASHDGISPADFPALRIETCVDKKTLAEAVIARAKSNRKM 80  Pectobacteri...
WP_013319851      1 MTTLIHVLGADIPHHNQTVLRFFNDTLAPSlpSHQVRRFMVVSAAELSGHAYPALQIARFADQKALARAVVVQAREDRSV 80  Dickeya dada...
ACL32679         35 MANIIHVLGANIPHHNHTILNFFQNELLDElpNA--FHFYVVSRSD-LSETFTLLDINSYPDEYLLTQEVIKIARKEPTA 111
Q7VKN8            5 MNPIYHLLSSDIPQHNQSVLDFFQSQLLPVlaDQQ-HIFYVVNQTR-LQEQYPALKLHCFNSKGAIAKAVLQVAKKEPNA 82  [Haemophilus...
WP_015431777      1 --mLYHVLGSDISQHNQTLLQFFQEDILPN--STQKHHFYVVSKQE---LNYPQLLLTRFESKKAIALALITLAKREPQA 73  Bibersteinia...
CCH:MU9_246      81 RFFFHGQFNALIWLALLSGKIKRHQFYWHIWGADLYEDSRQLKFRLFYHLRRLAQKRVGHVFGTRGDLNYFAQ--FCPKI 158
WP_002444169     79 GLFFHGQFNTGVWLALLRGGLKPARVSWHIWGADLYEVSSSLKFRLFYLIRRIAQGRVGRVFATRGDLDYYHQ--RHPVV 156 Shimwellia b...
wugsc:KPN_04293  78 RFFFHGQFNTGLWLALLSGGIRPSQFNWHIWGADLYENSASLKFRLFYPLRRMAQGRVGRVFATRGDLSWFAN--RHPRV 155
P56258           79 RFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAK--THPKV 156 Escherichia ...
KFD00376         80 HVFFHGQFNPTLWLALLTGKIKSQQASWHIWGADLYESAGGLKFRLFYFLRRLAQGRIGHVFATRGDLIHFHR--RHPRV 157
Q7MYM4           81 RFFFHGQFNVSLWLALLSGKIKRHQFWWHAWGADLYEDSQQLKFRLFYFLRRLAQRRVGHVFAVRGDLYFYSQ--HHPNV 158 Photorhabdus...
BAN96834         74 RFFFHGQFNPRLWLALLSGKLRRQQAFWHVWGADLYEEGAGLKYRLFYLLRRIAQGRMAQVFATRGDLHFFQQ--RHPRV 151
Q6CZF0           81 RFFLHGQFNPTLWLALLSGKIKPEQVCWHVWGADLYEEANGLKYRLFYWLRRMAQKRIGHVFATRGDLAWYEQ--RAPRV 158 Pectobacteri...
WP_013319851     81 RFFFHGQFNPWLWLALLCGGIRTTQAYWHIWGADLYEEARGWRYRWFYRLRRLAQRRVARVFATCGDIDYFRR--RYPAA 158 Dickeya dada...
ACL32679        112 WFVLHGQFNTSLWLAILLGLVPANRCVWHIWGADLYELSSSLKFRLFYPLRRLAQRKIARLWGTLGDLNHAYQqlKRKSS 191
Q7VKN8           83 QFILHGQYNVWLWCAILVGKLPAYRCYWHIWGADLYQASTDWRFKLFYPLRRLAQQKFTHIWATRGDLAYVAQhlARQKR 162 [Haemophilus...
WP_015431777     74 RFILHGQYNIWIWFALFCGKLPACRVAWHVWGADLYEVSSRWKFKLFYPLRRMIQRRLPAIWATKGDLEYVWKhiRAKRE 153 Bibersteinia...
CCH:MU9_246     159 PADLLYFPTRMDPSLTVLTPPEPRGDDnMMILLGNSGDRSNRHKEALTRIHEQF-GEKVKIIIPMGYPENNGDYIAEVDA 237
WP_002444169    157 PGQLLYFPTRMDPQLNTLADSITRQGP-LTILVGNSGDRSNNHIAALQAVHRQF-GDTVNVVVPMGYPANNQAYIDEVEQ 234 Shimwellia b...
wugsc:KPN_04293 156 PGELLYFPTRMDPALNTLADNDPRGDT-LTILVGNSGDRSNEHIAALKAIHQQF-GDTVNVIVPMGYPAKNDAYINEVRE 233
P56258          157 RGELLFFPTRMDPSLNTMANDRQREGK-MTILVGNSGDRSNEHIAALRAVHQQF-GDTVKVVVPMGYPPNNEAYIEEVRQ 234 Escherichia ...
KFD00376        158 PSSLLYFPTRMDPALTLPADQPEPAGP-MTVLVGNSGDRSNRHIEALRALHQQF-GADIRVIIPMGYPAHNDAYIDQVRS 235
Q7MYM4          159 PTSLLYFPTRMEPALTIAERVPVEDGK-MTILLGNSGDRSNRHITALKVIHKQF-GDKVRIIIPMGYPENNQVYINQVEQ 236 Photorhabdus...
BAN96834        152 PTSLLYFPTRMPEAAIPAPAASDS----FTILLGNSGDRSNRHIEGLQAIRRQF-GEQVNVVIPLGYPASNYEYIDEIDA 226
Q6CZF0          159 PTSLLYFPTRMDPALTSMKVDKPLAGP-MTILVGNSGDRTNRHQEALRAIHKQF-GNNVRVIVPMGYPANNASYIAQVEK 236 Pectobacteri...
WP_013319851    159 ATSLLYFPTRMSPHAASPHEKAPDAP--LSILVGNSGDPSNRHLAALDAIHRQF-GAQAQVIVPMGYPAGNHAYIEQVAQ 235 Dickeya dada...
ACL32679        192 LDQRLYFPTRMPTNFPTKKCSYQR-----TILLGNSGDPSNQHLLGLKQIREIF-GENVRIVVPMGYPAGNSKYIAQVRQ 265
Q7VKN8          163 DDRLVYFPTKMRSARWLAPPKEHNAATkITILLGNSGDPANQHLTALTHIKQSLsAQSVKIIIPMGYPAHNQRYIQQVKQ 242 [Haemophilus...
WP_015431777    154 RDRLIYFPSKMPNLQWGYDRKSLEDGE-LTILLGNSGDRSNNHLAALSQLNQYL-GHAIKLVIPMGYPANNESYIREVEQ 231 Bibersteinia...
CCH:MU9_246     238 FAQQLFPQQQAEILKDKMDFDIYLNLLKQCDLGYFIFNRQQGIGTLCLLIQFGIPFVISRQNPFWQDMTEQQVPVLFYGD 317
WP_002444169    235 AGRGLFSTGHLRVLREQMPFAEYLQLLRTCDLGWLTFERQQGIGTLCLLIQAGIPCVLSRKNPFWKDMVAEQLPVLFEGD 314 Shimwellia b...
wugsc:KPN_04293 234 AGAALFSGEHLQILSEKLEFHDYLALLRRCDLGYFLFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMAEQHVPVLFTSD 313
P56258          235 AGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTD 314 Escherichia ...
KFD00376        236 EALKLFAAENVELMTGSMPFAEYLDVLRGCSLGYFIFDRQQGIGTQCLLIQFGVPFVVSRQNPFWQDLAEQHLPVLFYGD 315
Q7MYM4          237 AALSLFRPENLNIIKQNMAFDDYLALLRRCDLGYFMFNRQQGIGTICLLIQFGVPFVLSRQNLFWRDLIEQQVPVFFAGN 316 Photorhabdus...
BAN96834        227 AAQRLFPRGQVTLLRDRIDFTAYLQLLSRCQLGYFMFERQQGIGTLCLLIQAGIPFVVNRKNPFWRDLSEQGLPVLFSAD 306
Q6CZF0          237 DGLALFGVKNFQLLKDQLAFDDYLNMLRTCDLGYFIFDRQQGIGTLCLLIQFGVPFVISRKNPFWQDLTEQSLPVLFYGD 316 Pectobacteri...
WP_013319851    236 HGLALFGADRCRVLRESLAFDDYLALLRTCDLGYFLFHRQQGIGTLCLLIQLGVPFVISRHNPFRLDLVEQRLPVLLGEE 315 Dickeya dada...
ACL32679        266 QAEQDFQQGQVNILTQKLEFESYLDLLSQCDLGYFPFERQQGIGTMCLLIQMNIPIAIHRANPFQQDLQAEGISFLFA-D 344
Q7VKN8          243 QAERLFPVNTVQILTEKLSFTDYLALLQQCDLGYFNFTRQQGIGTLCLLIQLGIPCVLHRQNPFTLDMDYEQIPFLYH-D 321 [Haemophilus...
WP_015431777    232 SAKRLFLSENVQILRSKIDFAEYLHILTACDLGYFNFERQQGIGTICLLIQQNIPVVLHPNNPFCCDLQAEQVPFLMI-D 310 Bibersteinia...
CCH:MU9_246     318 DVTPDVVAQAREQLFALDREKIAFFSPNFVQGWEQALAAAQE 359
WP_002444169    315 VLSEQIIRQAQRQLSCVDKQHIAFFNPGYLAGWHDALRLAAG 356 Shimwellia blattae
wugsc:KPN_04293 314 ALDVSVVREAQRQLASVDKSAIAFFRPNYLTGWQRALRLAAE 355
P56258          315 DLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAR 356 Escherichia coli K-12
KFD00376        316 ALDARTVAEARRQLLNTDRENIAFFNPNYIAGWQQALLLAAG 357
Q7MYM4          317 PLDSQLIAEAQRQMLSLDRNVIAFFSPNFIDGWRQALAKAAG 358 Photorhabdus laumondii subsp. laumondii TTO1
BAN96834        307 ALDRTRVAEAQRQLAQCDRSAIAFFAPGYLAGWRHALAESEr 348
Q6CZF0          317 DLDEALVREAQRQLASVDKHQIAFFNPNYLQGWRDALALATG 358 Pectobacterium atrosepticum SCRI1043
WP_013319851    316 TLNQAMVRDAREQLAHIDTRQIAFFSPGYEQGWRQALSLVAG 357 Dickeya dadantii
ACL32679        345 EISNSEIIRVKSQLALLDKSKITFFPLSYKQEWLNCLhslgl 386
Q7VKN8          322 QLNVTAIRQTQRQLAKVDKQQIAFFAPNYAKQWISLLTEvsq 363 [Haemophilus] ducreyi
WP_015431777    311 NLSQASLCQTREALLQCDKTKIGFFYPNYVKGWLACLEtml- 351 Bibersteinia trehalosi
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