Conserved Protein Domain Family
UBA_UBAC2

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cd14305: UBA_UBAC2 
UBA domain found in ubiquitin-associated domain-containing protein 2 (UBAC2) and similar proteins
UBAC2, also called phosphoglycerate dehydrogenase-like protein 1, is a ubiquitin-associated domain (UBA)-domain containing protein encoded by gene UBAC2 (or PHGDHL1), a risk gene for Behcet's disease (BD). It may play an important role in the development of BD through its transcriptional modulation. Members in this family contain an N-terminal rhomboid-like domain and a C-terminal UBA domain.
Statistics
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PSSM-Id: 270490
Aligned: 13 rows
Threshold Bit Score: 62.3633
Created: 23-Jul-2012
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8NBM4       305 VSEEQVARLMEMGFs-RGDALEALRASNNDLNVATNFLL 342 human
Q5ZJQ8       305 VSEEQVARLMEMGFs-RGDALEALRASNNDLNVATNFLL 342 chicken
NP_001074030 310 VTEEQVARLMEMGFs-RMDAQEALRASNNDINIATNFLL 347 zebrafish
NP_001165764 299 TSEEHVAQLMEMGFs-RADVLFALRASNNDINIATNFLL 336 western clawed frog
EDO43436     321 VSEDQVQTLVEMGFs-RQDVLHALTVTNNDINTATNVLL 358 starlet sea anemone
EDV25297     268 ISEDNVKTLVEMGFs-RYAVMQALQVTNNDVGLATNILL 305 Trichoplax adhaerens
XP_002160794 294 PSEEKIKTLVDMGFs-RADVVHALLSSNEDLQAATSLLL 331 green hydra
XP_003724694 349 TEEDKIEQLVDMGFn-RGAVMQALTMSNNDVTMATSVLL 386 purple urchin
EEC19092     319 ASFLQVQTLVDMGFd-RENVLRALRDSNNDVHLATTLLL 356 black-legged tick
EFO26063     305 SNEDQVRQLVDMGLgsREDVREALQQCGNDASEAANLLL 343 Loa loa
ELU15058     346 PTEEQIQQLIDMGFq-RERVMGALQENNNDVTGAINSLL 383 Capitella sp. I Grassle & Grassle, 1976
ADY47067     306 PSEDRIRQLMDMGFgnRQMVIDALRQNDNDTSAAANALL 344 pig roundworm
EFW46534     260 PSDEIVEQLTSMGFt-REAVLDALRQSNNDVMRATNRLL 297 Capsaspora owczarzaki ATCC 30864
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