2J3R,2J3W,3CUE


Conserved Protein Domain Family
TRAPPC5_Trs31

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cd14943: TRAPPC5_Trs31 
Click on image for an interactive view with Cn3D
Trs31 subunit of the TRAPP complex
TRS31 (also known as TRAPPC5) subunit of the trafficking protein particle complex (TRAPP). TRS31 is one of the six core subunits of TRAPP complexes which play a key role in the regulation of ER-to-Golgi and intra-Golgi transport by tethering the vesicle membrane to the target membrane.
Statistics
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PSSM-Id: 271346
Aligned: 74 rows
Threshold Bit Score: 131.502
Created: 14-Jan-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
BET3 interfacesedlin
Conserved site includes 22 residues -Click on image for an interactive view with Cn3D
Feature 1:BET3 interface [polypeptide binding site]
Evidence:
  • Structure:3CUE; Saccharomyces cerevisiae TRAPP membrane-tethering complexes; contacts 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1        ###### ## ##   #                #   #   #  ##  #                                
2J3R_B         5 VSVSAFALLFSEMVQYCQsrvy---svsELQARLADMGQGVGASLLDVLVmre--------------------------- 54  zebrafish
3CUE_B        57 ASLSAMAFLFQEMISQLHrtck---tagDFETKLSDYGHNIGIRLLELLNfrasvspsslprasaflsqnesssklsnas 133 baker's yeast
EER06315      16 VSQASVAHLFSEMVCYAVrrqg--pdneHLESKLHKMGASMGPGLLELTYmrdts------------------------- 68  Perkinsus marin...
A0C1N5        18 LNFCTFNYVFAEYICYLKrkhg--ndynEMNSKMEQLGVSVGIRLYEVVSlr---------------------------- 67  Paramecium tetr...
EQB60500       3 ENETFVKYMICTLIEDLRek------hlNIEEEMKKIGHILAKSILEVVD------------------------------ 46  Nosema apis BRL 01
Q8SU25         5 VPVSTMSYLVCGMIEYLMeq------rsDIEADLKSIGYEVGIKLLELCN------------------------------ 48  Encephalitozoon...
XP_001708336  22 VPLSSMVCLLNEYFQYAQrtck---tveEIENKMSKLGVDAGRPLWTYVRmldrmr------------------------ 74  Giardia lamblia...
CBH14661      23 VSLSAFSFLFSELCTRAHstptkardieEIEQRLTSLGAIVGAKLMMLSSlkdp-------------------------- 76  Trypanosoma bru...
EEQ82325       3 EDNDFLKYAICALIQDLKdn------neDIEQEMKKVGHILGRMALEHDD------------------------------ 46  Nosema ceranae ...
KCV70840      87 VSLAALAFLFSEIVKMANeagg---gieKIEQRLFEVGYSVGIRAVELAYirgsgl------------------------ 139 Fonticula alba
Feature 1                                                               ## ##                    
2J3R_B        55 ----------------------------------knGKRETKVLNILLFIKVNVWKAlFGKEADKLEQandddkTYYIIE 100 zebrafish
3CUE_B       134 nspgmlansstatsasanerlqekqteslsnyitkmRRRDLKILDILQFIHGTLWSYlFNHVSDDLVKsserdnEYMIVD 213 baker's yeast
EER06315      69 --------------------------------rnmsRKRDYKVLPLLYHIATYLWKAlFGHEAEVLTTdq--ecEFYLAD 114 Perkinsus marin...
A0C1N5        68 ----------------------------------erNKRETKLVEQLRFIQGIFWKHlFGRQAESIEKlkdrpnDYLIRD 113 Paramecium tetr...
EQB60500      47 ------------------------------------FKRELDIQSLLYKITYNLLDR-LYATNRKLESsienknEFFIFE 89  Nosema apis BRL 01
Q8SU25        49 ------------------------------------FEREVRISTLLYRATFDLLSL-VSDSDRRVEKardvdrTYLLTD 91  Encephalitozoon...
XP_001708336  75 ------------------------------sktqdtVCKLTRPDTVLYYLKETVWPIlFGKPAADIKKpatedlEYYLVD 124 Giardia lamblia...
CBH14661      77 ---------------------------------lelQRRPTTIDEALKLLQEKFWTRwFGKTANDLQQege-stRYFLVD 122 Trypanosoma bru...
EEQ82325      47 ------------------------------------FQRELDLESLLYKITYTFLDK-IYSTSRKLEVstknskEYYIFE 89  Nosema ceranae ...
KCV70840     140 ------------------------------geqstpLLRSTTIVEILQIIQTVLFPMlYGTRLGPIERdts-rnHYYLID 188 Fonticula alba
Feature 1                                    #                                          
2J3R_B       101 KEPLinayisv------pkenstLNCAAFTGGIVEAILTHSGFPAKVTVHWHk---------gTTLMIKFD 156 zebrafish
3CUE_B       214 NFPTltqfi----------pgenVSCEYFVCGIIKGFLFNAGFPCGVTAHRMpqgg---hsqrTVYLIQFD 271 baker's yeast
EER06315     115 KQWIlnkfislpp-vsddsddnfVNCAAFAAGLIEGAINAVGMQCKCTAAYTsedpe-tdpmaITIIVDFD 183 Perkinsus marinus ATCC 5...
A0C1N5       114 ENPLllkyi---------seeghISPAQFMCGILKGVLNASGFTCQVSYQFKtdergvsyyphTVFILSFE 175 Paramecium tetraurelia
EQB60500      90 YEPMysryvsl------pedwkdFCPESIICGVIEYTIMASGFDCEVNGFIRpvdk---fpdqVIYCIKIL 151 Nosema apis BRL 01
Q8SU25        92 SDGLfsrfisv------pdewngLSADSIVCGMIQAALMASGYDSEVTAFPEpsen---lpnrVIFQIRIL 153 Encephalitozoon cuniculi...
XP_001708336 125 EWPVleyytsy------ppnyggALPSMFVAGLVEGFLTCCGFRTKILAYNVldep----npnITFHISFT 185 Giardia lamblia ATCC 50803
CBH14661     123 SNPMvlqhvypspeymdsegqwsINYASFMGGIVEGALRAVGFDADVLTYHHpepd---kpqqSIFAISFA 190 Trypanosoma brucei gambi...
EEQ82325      90 HEPLfsqhvsl------peswkdFCPESIMSGVIEYALLASGFECEVNGYIKpckn---ntntVVYQIKLN 151 Nosema ceranae BRL01
KCV70840     189 DDPVvsqfisv------padmkdLNCGAYNAGIIAGFLERAQFPASVSAHNHaskd---lpsrTVYMVMFE 250 Fonticula alba

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