Conserved Protein Domain Family
PRK11930

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PRK11930: PRK11930 
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional
Statistics
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PSSM-Id: 237026
Aligned: 19 rows
Threshold Bit Score: 1151.63
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
161511189  16 RV--G-EHEATIDWLLTDSRSL------SFPEETLFFALPTKRNNGARYISELYDRGVRNFVVteedfkrmengewkmen 86 
284037156   1 ML--TkEFQLTNRHWFTDSRQVtghaadSLANEAVFFAILGEHHDGHAFIGDLYRKGIRQFVIers-------------- 64 
146299078  16 WT--GsDTDIFVDHISIDSRSL------QNGPQTLFIALSGANNDAHLYIAELIEKGVQNFAV----------------- 70 
150025143  19 FQ--GiDENIYYDTISIDSRSL------QNNENTLFFALVGPNNDAHIYIGDLISKGVKNFVV----------------- 73 
110640090  39 CIqqStEPNTFIKQLVIDSRKL------MAPAGAVFFAIDGKHHDGHAHITEMYKKGVRIFIV----------------- 95 
255536698  16 LI--G-DGKLCVTGMAYDSRNI------FSPLNTAFLAINTAKNSGEKYITSAIEKGISVVIS----------------- 69 
297620915  17 GD--S-NRPALIDQIVIDTRRI-------YASNALFAALKGQRQDGHSFVS---GSGAKFALV----------------- 66 
256419281  15 LL--QqTGNPEIEHILLDSRKL------SFPETSLFIPLVSSRRNAHQYIQELYEKGVSNFIV----------------- 69 
255532920  19 NF--EvQKDAIISKLVIDSRSV------IDPDGSLFFALKGQR-DGHGFLKDAYANGIRNFVI----------------- 72 
255038732   4 tvntSpIVTTQAQYILTDSRQV------SFPGQSIFFAIKGERHDGHRFLPELYAAGVREFVVeea-------------- 63 
161511189  87 amqqdgaqPTPNSRLSILDFSNFLIVANPLKALQKLAEAHRENFKIP-VIGITGSNGKTIVKEWLHQLLSPDRCIVRSPR 165
284037156  65 -----altPERREELATYADAQFTKVDSSLQTLQTLAAEHRRQFRIP-VIGITGSNGKTIVKEWLAQLLADEYVIARSPK 138
146299078  71 ----------QYIPENVKGKANFFVVKNTLKALQELAAYYRDLFDFP-IIGLTGSNGKTIVKEWLNFLLSPDYNIIRSPK 139
150025143  74 ----------TYIPKRLTGKANFLIVKNTLVALQIFARYYRNLFHFP-IIGITGSNGKTIVKEWLNFLLSPDYNIIRSPK 142
110640090  96 ---------EKSISLNEIPQAACIRVKSSVSALQACAAYRRKQLDIP-IVAITGSNAKTIVKEWLSQTVAADYSVVKSPR 165
255536698  70 -----------QHRIESETDVTWIIVEDSLKFIQKLAKYHFAQFTLKtTIGITGSNGKTIVKEWLYQSLFDEFITVKSPK 138
297620915  67 ----------EKHWEGPADGPSLLKVDDPLTAFQEIAGSYRSQLRGN-VIAVIGSYGKTMVKDLLRHLLSSSFTVASSPE 135
256419281  70 ---------SEPVPEGKYPKANIILVKDTMQALHALVAYHRQQFHIP-VIGITGSNGKTIVKEWLYQLLEKDYNIVRSPK 139
255532920  73 ---------SEAKYTRLFPDANILLVQDVLLALHTIAKYNRNQYDLK-VLGITGSNGKTIVKEWLYQLLAADHNIVRSPK 142
255038732  64 -----aftGALRETAATWDDAQIWVVSSSIRALQQLVASKRKQFDIP-VVGIAGSNGKTIVKEWLVQLLSPGRSIVASPK 137
161511189 166 SYNSQIGVPLSVWQLNEEAELGIFEAGISEMGEMGALKRMIKPTIGILTNIGGAHQENFFSLQEKCMEKLTLFKDCDVVI 245
284037156 139 SYNSQLGVPLSVHQLNESHTMAIFEAGISQTQEMQALEAIIRPTIGIFTNIGTAHDQGFRTRKQKVAEKLRLFIHAGTLI 218
146299078 140 SYNSQVGVPLSVIAINEKHNLGIFEAGISTVNEMVNLEKIIKPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVII 219
150025143 143 SYNSQVGVPLSVIAINENHNLGIFEAGISTKDEMENLQKIIQPTIGILTNIGTAHDEGFADISEKIKEKLKLFTAVEVLI 222
110640090 166 SYNSQIGVPLSVWALNERHTIGIFEAGISTTKEMQALQKVIEPTIGIFTNIGSAHDKGFKNREEKIQEKLKLFADCKVVI 245
255536698 139 SFNSQLGLPLSLLKVSARDEIGIFEVGISKPSEMERLADIFKPQIGVLTHIGPAHESNFENQKQLIEEKIKLFSDSDVIL 218
297620915 136 SFNSQVGVPLSLLGAAKAHEQVIIEAGFSHPGEMARLCKIIRPSHIILTHVGNKHLHTIGSKEQIAQEMCHFSLSSDASW 215
256419281 140 SYNSQIGVPLSVWQMKPEHQLAIFEAGISQPGEMEHLEKIIRPNIGIFTNIGEAHNEGFLNIRQKINEKLVLFSKSDLLI 219
255532920 143 SFNSQIGVPLSVWEITAIHTLGIFEAGISKTDEMDALASMIKPNVGILTNVGEAHAEGFVSLKEKLLEKLKLFNDADLFI 222
255038732 138 SYNSQIGVPLSVWNLSKEHSLAIFEAGISKAHEMEYLQPVMQPTIGIFTNIGPAHDDGFRSRKQKITEKLRLFTKVKKLI 217
161511189 246 YNGDNELISNCV----------AKSMLTAREIAWSCKDIERPLYISKVTKKEDHTVIAYrylDMDNIFCIPFIDDASIEN 315
284037156 219 YCTDYADIDEEVnl------llKAVNPDMRFITWSLTGQKATYQGRIAGNQVSLTGKNT---GFDQPLTLPFTDPASVEN 289
146299078 220 YQ-KNELVDKCLldf-----saQYPLENRALFSWSFADASADVFILKKETKNDSTTIKYqykDEIFNLEIPFSDSASIEN 293
150025143 223 LNKNKTIE--------------TFINKEINTFTWSTNDQSADVFFQK-KTLNDHALLNItnqGKYFKIKIPFIDEASLEN 287
110640090 246 YCSDHEEIHAEI------------TAQHLPTFNWSLQS-SATIEYSIAAKDSFQTQIEVktkEHQGFFYLPFVDDASIEN 312
255536698 219 FNGDNLLVHSLI----------TERYSSKKLISYGFETHNDIF----IKSSPKEGDLSIvyfGEEFNLPAQRRDEATLNN 284
297620915 216 TLLPKDPILSPL----------------PKPYYWDTPQPN----LPHASFHENSKAITVqfpKGDAHTILRPLGMSYILD 275
256419281 220 YSKDYLALNECVlnfhnlvgkkDNHEGGLQLFTWSRKT-EADLRIISVDKSEHHSRIDAlyqTIPIHINIPFVDEGSVEN 298
255532920 223 YAPEYTAGLS------------TDDLPGKTKFSWSKKQ-QADLQILFVEPIDGKNYIRAdfkGIEIECLIPFSDQASVEN 289
255038732 218 YRKDYHEIDEEIsl------ilKPVNAFLETLSWGSNYSGSHVQVTF-NPQKDKTVISLtgkLGNHTFETGFRDDASLEN 290
161511189 316 ALNCLAACLYL-MTPADQITERMARLEPIAMRLEVKEGKNNCILINDSYNSDLASLDIALDFLVRRSEKKglKRTLILSD 394
284037156 290 LMHCLVTMLSLrTWSAAELQSRLNRLRPVSMRLEQKEGINNCELIDDSYNNDMVGLQLALRFLNQQGTRS--RRIVILSD 367
146299078 294 AISCLLVLLHF-EYDFTIIQNRMEMLYPVEMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKKNA--SKAVILSD 370
150025143 288 SMHCILVMLYL-KYDLDTIKHRISQLFPVEMRLKVKNGINNCTLIDDSYSSDFQSLKIALDFLENQKQHL--KKTLILSD 364
110640090 313 ALHVATTLFYL-GYSIQEVSRKISGLQAVGMRLELKEANNDCYLIDDSYNNDLAGLSIALDFLEHVKQSE--VKTVILSD 389
255536698 285 ALCVIAVLKVL-GFSTDIIREKINMLKPVEMRLESVKGLRNNLIINDYYNLDLDSLKIAFQFINEYNKPA---KTLVLTD 360
297620915 276 LINIGLKAAYLlGVPEKQIVDALKTYQPEPMSTEIWKSQNGATFINETYCEDPQSLDCALRRFDFHSPKG--KKTLLFSG 353
256419281 299 AIHCWALMLHL-GMEHSVIQQRMDQLGNIAMRLELKQGINNCSVINDSYNSDLGSLAIALEFLQQQQQHP--TRTVILSD 375
255532920 290 GIICWATLLAL-GYTPEEADKRLEKLTRVSMRLELKNGINQCSVIDDSYSADISSLAIALDFLNLQNQHP--KKTLILSD 366
255038732 291 LTHCIVFLLDF-GLEPAVIQERVLLLKPVSMRLELKEGINHSYIIDDAYNNDLQGLAMALNFLAQQEQRN--RKTVILSD 367
161511189 395 ILETGQSTATLYRRVAQLIKSRGINKLIGVGAEISSCAARFEg--tPERYFFPDTDALLRSGIFKTLHSEVILIKGSRVF 472
284037156 368 VLQTGQPEAEFYEQVGNLMRANEVGQFIGIGPVVSRNKLFFA----DGSQFFATTEEFLAQFSFSELRDSTVLVKGARPF 443
146299078 371 IFQSGFSNEELYSKVAQLISDNKINRVIGIGTTISSFQDKFP-----NSTMFQNTAAFIAEIENLNFNNETILIKGARSF 445
150025143 365 IYQSGLENEDLYVRVSQLIISNKINRVICIGGVISKYKNKFL-----NVISYLSTNDFIEDFDNLDFTNETILIKGSRHF 439
110640090 390 VLESGLDSAVLYKEVASYLTTAQVQRVIAIGSQITELKKWYN----GRAEYYPTTEAFIKDLTKTVFEKEIVLVKGARIF 465
255536698 361 FVE-GKETTLLYQTVSNLTNQQKFQHVFLIGDEITKYSELFE----GDVAVFNNTTQLIESHYLDSVENELILLKGARKF 435
297620915 354 IKQN---DPALDARIGEAIGNSMPDTLMLIEPSFQLEHAVKTiapqTAIRHFSTVEAALKDHAGSMRPEDILIVKGKKKL 430
256419281 376 ILQSGKSDASLYEEVASLLQQKGINKVIGIGKNIFREKKSFQqitgLKSSFFLTTEEFIQQFNQQDFQHETILLKGARIF 455
255532920 367 IYETGKTNRVLYTEIAALLKQKHVDRLIGIGTHISESASLFD----MEASFYESTQAFIDNFPALHFNNETILVKGARRF 442
255038732 368 VLQTGQTPTELYKMVSRLLSEKSIDRLIGIGKQISSQASLFDi---AEQEFYDDTDSFLKTFAFPTLADTLVLVKGARPF 444
161511189 473 NFDLVSEELELKVHETILEVNLGAMVANLNHYRSMLRh----PETKMICMVKAAAYGAGSYEIAKTLQEHHVDYLAVAVA 548
284037156 444 SFERIVHRLERKVHGTVLEINLDALTHNLNYYRERISrndgpSETKIMVMVKAFAYGSGSAEVAQLLQFHRVDYLAVAYA 523
146299078 446 QFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSKLA-----DDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFA 520
150025143 440 EFEKIVTLLEEKTHETVLEINLNAISHNLNYFKSKLN-----PKTKIMVMVKAFGYGSGSFEIAKLLAHHKVNYLGVAFA 514
110640090 466 QFEKIVSRLQHKVHETVLEINLDALIHNLNVYRSKLK-----PDTKIMCMVKAFSYGSGGFEIAQLLQYHGVDYLAVAYA 540
255536698 436 EIEKVKDHLELQKHDTVLEVNLNAVLHNINVHKSLLK-----PKTKMMAMVKAYSYGLGGYEIAEFLQHHHIDYLGVAYA 510
297620915 431 PFDQLTQTVQGSIFSNQCRINLAAIASNIKQIRSRLT-----PHTEIMAMVKATAYGTQDALMAKFLKTEGIRRLGVSYI 505
256419281 456 EFERIGKLLEQKVHQTILEINLSAVTHNVKQYQSLLK-----PGTKLMAMVKAFSYGSGSFEIANLLQFHGVDYLAVAYA 530
255532920 443 EFERISKLIAQKVHDTVMEIDLNALAGNLQFYRSKLL-----PGVKVMAMVKAFSYGSGSFEIANLLQYHKVDYLAVAYT 517
255038732 445 SFEKIVHRIQQKAHDTVLEINLDALVHNLNYYRARAG-----QGTKIMAMVKAFAYGSGSSEVAALLQYHRVDYLGVAYT 519
161511189 549 DEGSELRKAGITSSIIIMDPELTSFKTMFDYKLEPEVYNFHLLDALIKAAEKE-G------ITNFPIHVKLDTGMHRLGF 621
284037156 524 DEGVSLRQNGVDLPIMVMNPAPETFSTLLEYKLEPEIYSLRLLREWEEFLRSReHafantqSTTYPIHLKIDTGMHRLGF 603
146299078 521 DEGISLKNGGIKLPIMVLNPESTSFPSIIQYKLEPEIYSIKGLNAFLKIAREK-N------LKDFPIHIKVDTGMHRLGF 593
150025143 515 DEGIELRQAGIQLPIMVLNPEMTSFPSIIQYNLEPEIYSIRGLKAFIKITQQK-E------LTSYPIHIKINTGMNRLGF 587
110640090 541 DEGARLRENGITLPIMVMNPTLSSFDTILRYELEPEIYEPVLLKQIIEYAQAK--------QKHIGIHIKIDTGMKRLGF 612
255536698 511 DEGADLRKNGISVPIMVMNPEQHSYDSIIEHHLEPEIYSFRVLDLFNQQLIRKgA------DKDYPIHIKLETGMNRLGF 584
297620915 506 DEGISLRKEGVDQDIFVLNAAPYEIEKAVSWQFEIAVNDKETIDQIGRMSSER-G-------TITRVHLHINTGMSRLGC 577
256419281 531 DEGVDLRRTGITMPIMVMNPEPSSFDAILQWNLEPEIYSLHLLKQFEEEVQLA-G------KTGFPVHIKLDTGMHRLGF 603
255532920 518 DEGISLRKAGITLPIMVMSPEPSAFDAIIRYNLEPEIYNIEILQGFIGFLKTD----------QYPIHLKIDTGMHRLGF 587
255038732 520 DEGVMLRQSGITLPIMVMNATLPTFDLLWQYKLEPEIYSRRILTDWIEYITRK-Ge----pTNTPSVHLKLDTGMHRLGF 594
161511189 622 SVDEIPLLIRRLKSQNAVIPRSVFSHFVGSDSAQFDFFTRQQIELFEKGSQELQEAFSHKILRHICNTAGIERFPGAQFD 701
284037156 604 LERELTVVTDFLKRQPNLHVATVFSHLVGADDAQFNPFSRQQYETFLRCTEFLGAELGYMPTRHLLNSAGIVRFPDYKLD 683
146299078 594 EDNTIDELIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFERLSSKLISELNINPIRHILNTSGISNFPDAQYN 673
150025143 588 DAQIIPELISILQKHDSVLVKSILSHLAASDDLAQDIFTRKQISDFDTISNKITTKLKINPIRHISNTSAISNYPQAQFD 667
110640090 613 EKKDVTEIAQQLKHTEFVKVYSVFTHLAASDSAEHDAFTAHQLNLFDEVISLFQTTLNYSFIKHAANSSGIMRFKEAHYD 692
255536698 585 REDEIDELAARLAKMD-VKVASVFSHLSTADSEEEHNYTMHQIEKFQSISTRLAEKLKYEPIRHILNSSGIANYADYQFE 663
297620915 578 RPEEALPLARIIQAHPHLKLEGVMTHFACSDNPDEDTFTLEQSRIFDHSIEAIEQEGISIPFRHACNSAAALRLHFPQYN 657
256419281 604 EKKDIPELARLLSDNIYLKVNSVFSHLAASEDPAMDAFTKQQGQLFFEMSHELQKALGYTVIRHIANSAAIERHPDLQLD 683
255532920 588 EEPDLSDLLKVLTETRKVKVASVFSHLVGSEDGLHDEFTRHQIERFTAMTELISETLHYPFIRHISNTSGISRHPETQLE 667
255038732 595 VKDDYEWLVEQLRQNPALKVATLFSHLVGADEGVHNEFSRKQYAQFMEGAELIEATLGYKTIKHILNSAGIVRFPEYRLD 674
161511189 702 MVRLGIGLYGVSPI--DNSIINNVSTLKTTILQIRDVPGEDTVGYSRMGHLTRPS-RIAAIPIGYADGLNRHLGRGNAYC 778
284037156 684 MVRLGIGLYGVEATgtEQSALQTVGTLRTIVSQIKTVGAGESVGYSRRGVLDHDA-RIATLAIGYADGYDRRLGNGVGNV 762
146299078 674 MVRLGIGLYGVSNDpaEQKYLENVGTLKSIISQVRTIPAGDSVGYGRRFMADKET-KIATIPIGYADGISRLWGNQIGFV 752
150025143 668 MVRLGIGLYGVSNDanETKKLENVGTLKSIISQIRNLNSGQSVGYNRRFMVKKPT-TIATIPIGYADGISRAWGNEVGYV 746
110640090 693 MVRLGIGLYGVESAglYQNELQAISVFKTHISQIKEITTEESVGYSRKGRVTKPS-KIATIAVGYADGYNRRFGNGIGEV 771
255536698 664 MVRIGIGMVGITSNeqIKNQLRNVVSFKSVISQISEINAGDSVGYDRKYKATKRT-RIATIPVGYADGVPRMIGNGIGHV 742
297620915 658 IVRIGMALYGLCPGg------tLALSLHSRIVGINHCIKGETISYGRSYTVQREReKIAVIPIGYYDGLHLNYSSK-GKV 730
256419281 684 MVRLGIGMYGIDSAnkIQDQLRPASTLKTTVAQVKHLSTGDTVGYGAKWVAKGPS-VTATVRIGYADGYPRRLSNGKGKM 762
255532920 668 MVRLGIGLYGFDAAlkNNTALQTVAILKTTITQIKHLKPNETVGYGRKGLLPKGG-TIATVKIGYADGYSRAFGNGTGRM 746
255038732 675 MVRLGIGLYGVEATgqDQRALQSVGTLKTIVSQVKYLSSGETVGYSRKGVVDHDS-AIATLAIGYADGYDRGLGNGVGKV 753
161511189 779 LVNGKKAPYVGNICMDVCMIDVTDI-DCREGDKAVIFGDD-----LPITTLSDKLGTIPYEVLTSISNRVKRVYYQD 849
284037156 763 WVNGSYCPTVGSVCMDMTMIDVTNA-SVSEGDEVLIFGPE-----LPITELARRIGTIPYEILTGVSERVKRVFFKE 833
146299078 753 TIKNQKAYIVGSVCMDMLMVDVSHI-DCKEGDSVIIFGES-----PTVIEMAEALKTIPYEIMTSISQRVKRVFFR- 822
150025143 747 LVNEQKAPIVGSICMDMLMIDVTKI-NCSEGNQVIIFGKT-----PSVTTIAKATKTIPYEILTSISSRVKRVFYRE 817
110640090 772 LVNGVRCPIIGNVCMDMSMVDVTDA-HAAQGDEVILFGHN-----PTVSDLAKRIGTIPYEILTSVGARVKRIFYSE 842
255536698 743 SISGNLYPIVGNICMDMMMVEVGDS-SAKEGDEVIIFNSK-----PSLAEFSDYCKTIPYEVLTSISRRVKRVYIKD 813
297620915 731 MIHGAEAPIVGRICMDYMMVDITHIpDACIGDPVLIFGEDaegnvLSPNELAEQGNSSVYELISCLGPRIQRVFIHE 807
256419281 763 LVRGQLAPVAGVVAMDMLMLDVTNIpEVAEGDEVIVFGNE-----LPVQQVSAWADTIPYEILTGISQRVKRVYFEE 834
255532920 747 LIKGKLVPTVGVICMDMCMLDVTGL-DVKTGDEVIVFNNE-----LSIAQLATQIGTIPYEILTNVSQRVKRVYFYE 817
255038732 754 WVNGTLCPTIGNICMDMTMIDVTNA-QVEEGDEVIVFGKE-----VPITELAKTINTIPYEILTGIGDRVKRVFFKE 824
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