2JNA,2MA4


Conserved Protein Domain Family
YdgH_BhsA-like
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pfam07338: YdgH_BhsA-like 
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YdgH/BhsA/McbA-like domain
This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.
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Statistics
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PSSM-Id: 429417
Aligned: 82 rows
Threshold Bit Score: 30.1827
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2JNA_B        36 VKVGTINVSqsggqISSPSDLREKLSELADAKGGKYYHIIAARE---HGPnFEAVAEVY 91  Salmonella enterica subsp. enterica ...
Q7N4Z4        36 KPFKRITVTg---pFNAIYEAADAVSRRADKMGADGFYIQSLDDlnnSGN-LRVTADLY 90  Photorhabdus laumondii subsp. laumondii
KFD10264      36 KPFDRIVITg---rFNTLGDAADAVSRRADTLGADYFYIQDTNStnnSGN-WRVVADIY 90 
Q32G70        35 KPFDRVVVTg---rFNAIGEAVKAVSRRADKEGAASFYVVDTSDfgnSGN-WRVVADLY 89  Shigella dysenteriae Sd197
WP_002441633  37 QSLGVIYINh---nFATEEEATRALDDRADTKGARFYSPILMHEpgsNGN-LHASAELY 91  Shimwellia blattae
P0AF86        36 QSLGVIYINh---nFATESEARQALNEETDAQGATYYHVILMREpgsNGN-MHASADIY 90  Escherichia coli K-12
VDY64823      37 KPYDRITITg---rFNAIGDAVKAVSRRADSMGAASFYIQDSNDsgnGGN-WRVVADVY 91  Shimwellia blattae
WP_015874134  36 TSFKQITLNg---rFNNLGEVAEAVSRQADKLSAYAFYVQGIHStnrGGN-WRVTANLY 90  Candidatus Hamiltonella defensa
WP_039695434  35 KPFERITFLg---rYDAIYEAASDASKKADERGAAAFYIQSTSEv-nGGR-WAVTVDLY 88  Dickeya fangzhongdai
WP_135147600  37 QPFERIAVTg---rFNAIYEAAAAVSRKADKMGADAFYIQSLDDlnnNGN-MRVVADVY 91  Escherichia coli
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