Conserved Protein Domain Family
ABC2_membrane_3

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pfam12698: ABC2_membrane_3 
ABC-2 family transporter protein
This family is related to the ABC-2 membrane transporter family pfam01061.
Statistics
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PSSM-Id: 463674
Aligned: 137 rows
Threshold Bit Score: 47.7698
Created: 24-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDO48951             878 KKSVVTQILLPMVMVL--FGLLI--M---NTGG-ARGNDPARLLNLKnlstdgvnTKVFFADFR-------Nr-SNT--A 939 
sklvwiv:Bsph_2248     12 KSFILMTCLYVLVMSVavFWSEI--K---ELFTgDDEAQQIAIIN-Dt-------SADLSGIFV-------S--NGD--M 67  
Q3Y1S4                19 ISFL-IMILVPFIMLGi-IYVAG--N---FAQQ-NSDVNKIGVLADNeq-----iSQQMSQVKT-------D--DFE--F 74   Entero...
Q835G8                19 lSFL-IMILAPFLLVGi-VYLAG--S---LASG-FSGDTTIGLVSEN---------QALVKELT-------K--NKTedF 72   Entero...
OTooleUCC:LRC_11120   22 WSFL-IMVLAPFLAIGl-GLLLG--K---VSSD-NAEDMVKDVTEIAvv----atSKNLQKQFE-------S--QTN--V 78  
WP_015911677          19 WSFV-LMVLSPFLFLAf-SAGIG--Y---VSGSsAEKSNKIAIILP---------QDNMKAAFK-------Q--LDH--V 71   Strept...
WP_012655915          19 KSFI-FSTLFMILIFVg-LSNAD--Ki--YDYF-DKSEDEITVISSSdk----alATAFKESYH-------K--LDK--K 76   Macroc...
CAL28741              19 RAFIIMTVIISLLIIGg-ANANK--I---IDMF-NGGPDKIGIVSEN---------QQVYQMVK-------Sq-SAK--I 72  
Q2FVS4                19 KSFVIFMIIIAALMIGl--SNID--Ki--INMF-DDGPDKIGVAAPNeq-----iYKVFKQQAN-------T--F----- 72   Staphy...
WP_012818920          19 KSFLVSTLIFALIITIg-INLPFliQmftGDKAgSDETTRIGLVYGQ--------EQTLAEQLEttwsslpAnsYEF--V 87   unclas...
EDO48951             940 QaqaTLQVLTDTVDVTNKVydirTKNALDGIHVVKSSYNYTTsagnccnykflvlnehcrndfldgnltssncsnndnfg 1019
sklvwiv:Bsph_2248     68 A---FIQDEKDIPALEKKV----KDGKLDAIVTIKDQGGQLQ-------------------------------------- 102 
Q3Y1S4                75 K------AVDSEEKAQKEL----SEEKIDAYLVVSTENDKI--------------------------------------- 105  Entero...
Q835G8                73 S----FKAVSSEKKAQEQL----KDEKIDAYLLLDTTDNQ---------------------------------------- 104  Entero...
OTooleUCC:LRC_11120   79 T-----IRYESLDKAKKAL----NKDKIAGYVSVSLKKGR---------------------------------------- 109 
WP_015911677          72 T-----FDYKDVQKAKKDL----KSDKILAYITLSENNQV---------------------------------------- 102  Strept...
WP_012655915          77 K----KLKIVDFKKGEEGI----KDETYKYLIDIKENEDKTIe------------------------------------- 111  Macroc...
CAL28741              73 EdkgTKFQHVSEKQAIKDV----KNEKLDKAYIIKTKG-KQVegeivsk------------------------------- 116 
Q2FVS4                73 Hs-dAKFTKVSIEDAEKEV----KKHKLDKAYIIKVNQNRTLq------------------------------------- 110  Staphy...
WP_012818920          88 K-----YETADEAALNQDI----KDGVIEGYLKFEAQEGNTFp------------------------------------- 121  unclas...
EDO48951            1020 ykhcdkclnsqtgkgcnppsisstnladmntyfdeyvleesnakqffyeyvagvtIGPLPSPGYVV--PATNVTNAsg-y 1096
sklvwiv:Bsph_2248    103 -----------------------------------------------------------AEIATFTplKLNDQSTLs--- 120 
Q3Y1S4               106 ------------------------------------------------------------NGMLYS--ENSLGQSTq--- 120  Entero...
Q835G8               105 -----------------------------------------------------------ISGQLYS--ERSLGNATemli 123  Entero...
OTooleUCC:LRC_11120  110 -------------------------------------------------------YEARYHGKGSI--DETSKAGIm--- 129 
WP_015911677         103 -----------------------------------------------------------ITAKYFS--KEEPSQSQk--- 118  Strept...
WP_012655915         112 -------------------------------------------------------------AKVYS--TEYASDSVm--- 125  Macroc...
CAL28741             117 ------------------------------------------------dsvsdetKQKLESILTPI--QTQAIAKSv--- 143 
Q2FVS4               111 ---------------------------------------------------------GTIISEKRV--SHEDSQKVq--- 128  Staphy...
WP_012818920         122 --------------------------------------------------------------TVVY--SSEDEAMSp--- 134  unclas...
EDO48951            1097 hIIASS-IN---A--LSNILLae--------------lSGDSEQGIETTNHPLpn------------naQNKA--DNVTS 1142
sklvwiv:Bsph_2248    121 -SLLQY-AG---QhyAVQQLSlspeqaa----qimaaqTTISTKNLNEESTGGks-------------eEEKQs-GLVVS 177 
Q3Y1S4               121 lLIQQQ-LT---G--LQSMLRasqlgispeevaslsqqASLTRQKVNFDSKGKmtv-----------geDNSTv-QYVVS 182  Entero...
Q835G8               124 pQMLNQ-LQ---T--MANANRlnltaeq---vamlnqqATFKKAKISFDENGKik-------------tGEDN--TGIQM 179  Entero...
OTooleUCC:LRC_11120  130 -NVLSR-LQssqNi-VAAQLNndqlhklq-vqpnfveiKNSASKQNQIDKKQQ----------------EKFA--NKTAY 187 
WP_015911677         119 -ALLTQsLN---G--LQQTLNvakaqi-----spqqleTLSTQAKLDVQTTNH----------------TNYDkiSKYIS 171  Strept...
WP_012655915         126 gAVRST-LT---A--FQSNNIaqslnlsqddlnrvmseAKVTDKVIKPKDANDn--------------vSEQS--KALNT 183  Macroc...
CAL28741             144 -NLSPKdLQ---A--LQQQSK-------------------VTAKVVGKDAKQLs--------------eQDKV--ANIII 182 
Q2FVS4               129 -ALLTA-IQ---Tn-MVAGELninkedl----qklqaqSKVDNKVISNDEVDKv---------------SEGQ--KIFNY 181  Staphy...
WP_012818920         135 -ELQSN-LQ---A--ALQVAKtrsive-----glnlsdAQINELNMPVQIDARsistnpsgnadgasdeKEGA--SEVIN 200  unclas...
EDO48951            1143 TISV---LFLAIFMSMGMAFMAASFitflV----QERTSKAKHLQFVSgVDAFSYWSATYTWDFLNYLVPC------LLI 1209
sklvwiv:Bsph_2248    178 YAVG---ILIYFFISTFLSMITTEI----A----SEKGSRAMEMLLVS-VKPTTHFKAKIAGVLLLALTQM------GIL 239 
Q3Y1S4               183 YVAT---IVLFIIILTYAQIIAQEI----A----SEKGTRIMEVILSS-TTAQKHFYGKLTGVLLVALTQM------ALY 244  Entero...
Q835G8               180 ALAMgitILLFVFISSYSSIIAQEI----A----SEKGTRIMEVILSS-TKAQTHFYGKLTGVILVALTQI------FIY 244  Entero...
OTooleUCC:LRC_11120  188 MILL---FVMYFILITYSTTTAQEI----G----SEKGTKIMEVLFSS-MPAKNYFYGKMLGLTIVIVLHI------SIY 249 
WP_015911677         172 FYGVt--FIMYMILIIYTSQTAQEI----A----SEKGTKIMEVIFSS-VPANHYFYGRILGIFAVILTHM------TIY 234  Strept...
WP_012655915         184 ALVYaglFLIFIITINYGSQIATEI----A----QEKSSRVIEMIITS-ISPITHLMAKILGVIAVAVTQMmmyaiaIII 254  Macroc...
CAL28741             183 LYAGi--MLMFFIILNYANQVAMEV----A----TEKISRVIEMVITS-ISPVKHLLAKILAIILVAFTQV------LIF 245 
Q2FVS4               182 ALAYgiiFLMFFIVLNYASQIAMEI----A----SEKTSRVIEMIITS-ISPIQHIFAKILGVIAVAVTQI------ILI 246  Staphy...
WP_012818920         201 YIVV---YALIILFFFTLMGTGNMI----AsevtTEKSSRIMEILITS-VSPLSQMFGKVIGMFLLGLSQI------AAF 266  unclas...
EDO48951            1210 LI---Lfa--aFQ-----------------------IEEFenDM-----GSVF--LLLILFGLVVLPFIYVMSFA-F-KS 1252
sklvwiv:Bsph_2248    240 AAv--Fl----IYaklvkggivw----dmaadivkeLSVG--YV-----IYAI--VFLLLTVILYLIIGALFGSL-V-SK 298 
Q3Y1S4               245 GI---I-----FGigysqfkdm-----emvknildgISLD--NLigpflWYSL--LFMIFGILIFSVLAALCGSL-VnKA 306  Entero...
Q835G8               245 GVa--Fv----LGysqlknldfmk--sllsgispqsIFSS--TF-----IFTL--GFFIIGILVFAVLAALCGSL-V-SK 305  Entero...
OTooleUCC:LRC_11120  250 AIgggVi----YAlaprlwgde-----alfktayemINIIfkHL-----ISINl-VYVLLMIILCTVLAALCGAL-V-VR 312 
WP_015911677         235 VAggyLc----FKlanklemtke---wiqnmkplldSLIK--HLd----WSIL--FFAIFGILLYVVLAALCGSL-V-VR 297  Strept...
WP_012655915         255 CI---Ya----FSleetv--------------nelgFTFGteNVri--lVYAI--IFLILGLLIYISSSAIIGSL-T-NR 307  Macroc...
CAL28741             246 VV---Vg---aISiylsdlrdiv----kkfnvkftdVTMH--LL-----IVGV--ICFIIGIISYTILGTILGSL-A-TR 304 
Q2FVS4               247 VL---MaviciFAfdlkdl------------lqgfnVEMN--QLswqiiIVGI--ISSIVGITAYVLLAAILGSL-T-SR 305  Staphy...
WP_012818920         267 GIv--Aa----VNlmlphnldtlkdmnldlsaidpmL-------------LVFglIFYILGYFLYAMLYAAIGSIvS-RT 326  unclas...
EDO48951            1253 Q-LI-A-YAMTVFVLSi-MSFGMLLA-VFlcrIP--SLNlldeaEIMHYVFMLLPTYTVSYALIDMS-Tnygyrkicstl 1324
sklvwiv:Bsph_2248    299 VeEA-G-QVLMPAMIIt-IIGFYVML-TG---MG--NPD-----TIIIKIFSYIPLTSGMIMPMRIG-Atdig------- 356 
Q3Y1S4               307 E-DT-A-KAILPVTYLs-LGGYMLGL-ILg--AS--DPN-----NIVIRITSYIPFLSSYIMPVRLA-Netvg------- 364  Entero...
Q835G8               306 PeDT-A-KAVQPIMYIg-LIGYMIGI-TFg--TN--DPQ-----NIVVKVTSFIPLISSYIMPVRLA-Tetas------- 364  Entero...
OTooleUCC:LRC_11120  313 I-ED-S-NKAVQPVMYl-IIAGFIASmAF---QG--KPE-----SVIVVALSYIPGVSAFFMPLRII-Ngtvg------- 370 
WP_015911677         298 P-EQ-A-NQAAQLPIFl-VIAAFMGA-FV---LGqgNSD-----PLLLKIGSYLPFFSTFFMPIRLI-Ngf--------- 354  Strept...
WP_012655915         308 I-EDiG-QAIMPVTMLn-MIAFYIAM-FS---LS--KPD-----TLLVKIASYIPFFTPQIMLLRTIsTkts-------- 365  Macroc...
CAL28741             305 I-ED-MnQALMPMTAVs-FIAFYIAL-LN---LN--TPE-----TMLTKIASFIPLLSPFVLFLRAS-Tpe--------- 360 
Q2FVS4               306 I-ED-L-NQSLMPLTLlgMIAFYIAI-FT---IN--NPD-----GQLALITSYIPFLAPFQLVVRAQ-Tsglq------- 363  Staphy...
WP_012818920         327 E-DL-G-QAVMPITMLs-LVAFYIAI-FS---LS--APN-----SMLMKVSSYIPFISPTTILVRIG-Lgdit------- 383  unclas...
EDO48951            1325 qtvescrdngiqftdsslnwdrpgVGQHALYMAVEAVVLFI-LTLL 1369
sklvwiv:Bsph_2248    357 ---------------------givPLLSLGILIATIIVVYL-FSLS 380 
Q3Y1S4               365 ---------------------mggALISLLVLVAVTFLLMI-LSAN 388  Enterococcus faecium DO
Q835G8               365 ---------------------tmeAIVSLVILAVFGIILTI-FSAr 388  Enterococcus faecalis
OTooleUCC:LRC_11120  371 ---------------------tigIGVSLTLFLATVILA---Ivwc 392 
WP_015911677         355 ----------------------ahLNQSLISLLILALTTLF-ITMY 377  Streptococcus uberis
WP_012655915         366 ---------------------dieIMIGIIICIITIILLLF-IAAK 389  Macrococcus caseolyticus
CAL28741             361 ----------------------lqLWEIIVSVLLSLIVMILlLWIA 384 
Q2FVS4               364 ---------------------iyeVILSSLISIVMVAVLIW-IAIk 387  Staphylococcus aureus subsp. aureus NCTC...
WP_012818920         384 ---------------------vweILLSLAILIAAILVFGW-LAAK 407  unclassified Paenibacillus
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