3MPB


Conserved Protein Domain Family
Lyx_isomer

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pfam07385: Lyx_isomer 
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D-lyxose isomerase
Members of this family of sugar isomerases belong to the cupin superfamily. The enzyme from Cohnella laevoribosii has been shown to be specific for D-lyxose, L-ribose, and D-mannose. E. coli sugar isomerase (EcSI) has been structurally and functionally characterized and shows a preference for D-lyxose and D-mannose.
Statistics
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PSSM-Id: 429437
Aligned: 38 rows
Threshold Bit Score: 356.093
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3MPB_A                   20 MKRSAINDILGHTRQFFSQHDVHLPPFASFSPAQWQQlD--TAAWEEVFDLKLGWDVTAFGRNNFAAHGLTLFTLRNGSA 97 
CCY39200                  1 MKRSEVNRYIKQAIKLFDENNFHLPSWALLTPEEWKD-KiaTERCKEIIDHTLGWDVTDFGKNNFMKEGLTLFTLRNGSP 79 
WP_013255525              1 MKRSEINAIIEGAQAFFSEQGFHLPEWAFWNPEQWAA-H--KNGCKEIFDCKLGWDITDFGSGRFETRGLTLFTLRNGLE 77  Sedi...
vbi:Arad_8189             1 MKRSEINAALRQASETLERWHWSLPDWGYWTTADFAA-N--PQAASYLRAHQLGWDVTDFGSGRFAECGLVLFCLRNGIV 77 
jgi:HSM_0820              1 MKRSEINQAIREAQQMMAKYHFVLPKFADFSLADWHTlS--LERYAEILEANLGWDVTDFNLGNFKQAGLTLFTLRNQSD 78 
Q9CL68                    1 MKRSEINQVLGEFKALMQRHCFYLPEFADYRLADWKLaD--LVSQQEVLDARLGWDVTDFNLNDFAKYGLTLFTIRNQSS 78  Past...
jgi:Tola_0050             1 MRRSQLNEILADSQALFAQHQIYLPPFAHFTPQDWTTqD--LTRFQEVFDLQLGWDVTDMGSNDFANTGLTLFTLRNGSV 78 
WP_024913819              1 MNRSSVNHILQQTRHFFTQHDVHLPPFAHFSPQVWQQlD--HKPWQEVFDLKLGWDVTAFGGNDFAHRGLTLFTLRNGSP 78  Chan...
Q329G4                    1 MKRSAINDILGHTRQFFSQHDVHLPPFASFSPAQWQQlD--TAAWEEVFDLKLGWDVTAFGRNNFAAHGLTLFTLRNGSA 78  Shig...
PRJNA326509:BAY22_00735   1 MKRSEVNQILKQTGHFFARHHIQLPPFARFTPQRWQQlD--PKAWQELFDLKLGWDITAFGGNHFFTQGLTLFTLRNGSV 78 
3MPB_A                   98 KGMpYVKCYAEKIMHVRDAQVTPMHFHWRKREDIINRGGGNLIVELWNAD-SNEQT--ADSDITVVIDGCRQKHTAGSQL 174
CCY39200                 80 K---SEKTYCEKIMVSYVNQITPMHFHWNKMEDIINRGGGILALQLWKANkKEEK---TSDSFTVQIDGITQNIEAGEII 153
WP_013255525             78 GS--YAKPYAEKIMVVGEEQETPFHFHWNKMEDIINRGGGKLAFELYMSDaQDGf---STQSVTVSVDGVQRVLEAGERL 152 Sedi...
vbi:Arad_8189            78 GVE-GERTYAEKLLFVEEGQVTPTHRHAAKMEDIINRAGGDLIIEFAATD-AAGNV--TKDDVTVPVDGLPFRLAAWEPL 153
jgi:HSM_0820             79 RN---NKPYAEKIMLVKQNQITPMHYHWKKMEDIINRGGGILVIQLYRRD-EITELldKVSSIDIQIDGEQYQVAAGSKI 154
Q9CL68                   79 TN---QKPYAEKIMMVKEGQVTPMHYHWKKMEDIINRGGGTLVIRLYRRD-EQTDLldEKSTIQVAVDGKQVTVNAGGLV 154 Past...
jgi:Tola_0050            79 GGKpYPKPYAEKIMISREGQQTPLHFHWYKMEDIIHRGGGNMIIELYNRT-ADEQC--DTTDVEVVLDGERQRHKAGSRL 155
WP_024913819             79 SGQpYSKCYAEKVMHCREAQVTPMHFHWRKSEDIINRGGGNLIVELYNAD-QQEQL--AASEVTVVLDGCRQTHAAGSRL 155 Chan...
Q329G4                   79 KGMpYVKCYAEKIMHVRDAQVTPMHFHWRKREDIINRGGGNLIVELWNAD-SNEQT--ADSDVTVVIDGCRQKHTAGTQL 155 Shig...
PRJNA326509:BAY22_00735  79 SGTpYPKCYAEKIMHVREGQVTPMHFHWRKQEDIINRGGGNLIVELWNSD-AFEQT--EKSDVTVTLDGCRQTHAAGSQL 155
3MPB_A                  175 RLSPGESICLPPGLYHSFWAEagFGDVLVGEVSSVNDDDHDNHFLQPLDRYNLIDEDEPAQLVLCNEYR 243
CCY39200                154 RLNPGESITLEPYIYHQFWAE--KETCIIGEVSKVNDDSNDNRFYEPLGRYPEIEEDESPLFLLCTEYl 220
WP_013255525            153 VLDPGSSLSLPQRLYHRFFAVkgYGKVMCGEVSMVNDDDSDNRFKEELGRFPAIEEDVPPTRLMVGDYR 221 Sediminispiroch...
vbi:Arad_8189           154 VLSPGQSVTIHTGLYHRFYGRkgDGPVLVGEVSQVNDDNNDNFFLEPIGRFAAIEEDEPPLRPLWNeag 222
jgi:HSM_0820            155 RLSPGQSICLPPMLYHSFWAE--DSDVLVGEVSMTNDDLTDNRFLESLGRFSTIQENEQPIRLLCSDYK 221
Q9CL68                  155 KLKPGQSICLTPFLYHSFWAE--DGVVLAGEVSMANDDLTDNRFLAPLGRFSHIEEDEPPLHLLCSDYP 221 Pasteurella mul...
jgi:Tola_0050           156 RLTAGQSISLTQGLYHSFWAEpgHGPVILGEVSMVNDDRRDNRFLRPQSRFSEIEEDTDPLHLLCNEYA 224
WP_024913819            156 RLAPGESICLTPGIYHSFWGEegFGDVLVGEVSMVNDDDHDNRFLLPLSRFDPIEEDQPPKWLLCNEYR 224 Chania multitud...
Q329G4                  156 RLSPGESICLPPGLYHSFWAEtgFGDVLVGEVSSVNDDDHDNHFLQPLDRYNLINEDEPAQLVLCNKYR 224 Shigella dysent...
PRJNA326509:BAY22_00735 156 RLSPGESICLVPGVYHSFWGEvgYGEVLVGEVSMVNDDDHDNRFMKPLERFNSIIEDEPAELVLCNEYC 224
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