1QU0,1C4R,1F5F,2SLI,1SAC


Conserved Protein Domain Family
LamG

?
cd00110: LamG 
Click on image for an interactive view with Cn3D
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Statistics
?
PSSM-Id: 238058
Aligned: 113 rows
Threshold Bit Score: 47.7981
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1QU0_C    10 GTYFDgt---gFAKAVGgfkv-----gldLLVEFEFRTTRp--TGVLLGISsq-----kmDGMGIEMI-------DE-KL 66   house mouse
2SLI      11 NVDIAeg---qGYSLDQeagakyvkamtqGTIILSYKSTSengIQSLFSVGnsta-gnqdRHFHIYIT-------NSgGI 79   North American leech
1SAC_A     8 VFVFPresvtdHVNLITplek----plqnFTLCFRAYSDLs-rAYSLFSYNtqg----rdNELLVYKE-------RVgEY 71   human
1620510 1550 GIYFSqg--ggHVILANsvsl-----gpeLKLTFSIRPRSl--TGVLIHVGsq-----sgQRLSVYME-------AG-KV 1607 Norway rat
3043590 1471 GLFFPgs--ggVITLDLpgat-----lpdVGLELEVRPLAv--TGLIFHLGqar----tpPYLQLQVT-------EK-QV 1529 human
2851576 3436 GLFFPgs--egVVTLELpkak-----mpyVSLELEMRPLAa--AGLIFHLGqal----atPYMQLKVL-------TE-QV 3494 house mouse
2558825   72 GANVGrp---aRTLIPPtff-------rdFAIGVAVKPNSa-qGGVLFAITda-----fqKVIYLGLRlssvedgRQ-RV 134  house mouse
1125776  766 IVHLSts--esENHLLRn----------hIELSFLMHSGKp--DAVLFYIGekhaadvltNYLVVKIA-------GG-LI 823  Caenorhabditis ele...
7481072  447 ALAFDga--ddAVRLPYdgrla--lgegdFTASLWFRYSAadgEQPLLWMGgigt-tqpqVWLRAEPD-------AG-RV 513  Streptomyces coeli...
2493781   72 AYRVTee---aQISAPTkqlfpggifpqdFSILFTIKPKKg-tQAFLLSLYne------hGIQQLGVE-------VGrSP 134  house mouse
1QU0_C    67 MFHVdng------agrFTAIydaei-pghmcNGQWHKVTAKKIk--NRLELVVDg----nQVDAQspnsas-tsadtnDP 132  house mouse
2SLI      80 GIELrntd----gvfnYTLDrpasvralykgERVFNTVALKADaanKQCRLFANge---lLATLDkdafkfisditgvDN 152  North American leech
1SAC_A    72 SLYIg----------rHKVTskv-----iekFPAPVHICVSWEsssGIAEFWINgt---pLVKKGlrqgy---fveaqPK 130  human
1620510 1608 TTSVssda----ggsvTSITpkq-----slcDGQWHSVAVSIKq--RILHLELDtd---sSYTVAplsfs---pnstrGS 1670 Norway rat
3043590 1530 LLRAddga----gefsTSVTrps-----vlcDGQWHRLAVMKSg--NVLRLEVDaqs-nhTVGPLlaaa-----agapAP 1592 human
2851576 3495 LLQAndga----gefsTWVTypk------lcDGRWHRVAVIMGr--DTLRLEVDtqsnhtTGRLPesla------gspAL 3556 house mouse
2558825  135 ILYYtepgsh-vsreaAVFSvp-------vmTNRWNRFAVTVQg--EEVALFMDcee-qsQVRFQrsswpl--tfepsAG 201  house mouse
1125776  824 TVRYrtgg-----rreIEFSskn-----rvdDNQEHHVQIFLDk--TTRQIIIDd-----LIECSepiisrmsqefyvDD 886  Caenorhabditis ele...
7481072  514 QGLItardga-taprsAWVRtdr-----aydDGRWHRLTLRRGg--GRLTLFVDgs---aAADAAdvpgsv--srnspFG 580  Streptomyces coeli...
2493781  135 VFLFedhtgkptpenyPLFStvn------iaDGKWHRVAISVEk--KTVTMIVDck---kKITKPldrser-sivdtnGI 202  house mouse
1QU0_C   133 VFVGGfpgglnqfglttniRFRGCIRSLKLT 163  house mouse
2SLI     153 VTLGGtkrqg-----kiayPFGGTIGDIKVY 178  North American leech
1SAC_A   131 IVLGQeqdsygg-kfdrsqSFVGEIGDLYMW 160  human
1620510 1671 LHVGGvpdklkmltlpvwnSFFGCLKNIQVN 1701 Norway rat
3043590 1593 LYLGGlpepma--vqpwppAYCGCMRRLAVN 1621 human
2851576 3557 LHLGSlpksst--arpelpAYRGCLRKLLIN 3585 house mouse
2558825  202 IFVGNagam-------gleRFTGSIQQLTIY 225  house mouse
1125776  887 IVIGAsnvva-----tdseFYKGYLQDIQIN 912  Caenorhabditis elegans
7481072  581 VHIGErmd--------graRFTGAVDDVQVW 603  Streptomyces coelicolor
2493781  203 MVFGTril--------eadVFQGDIQQFLIT 225  house mouse
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap