4Y2W,1BD0,2ODO


Conserved Protein Domain Family
Alr

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COG0787: Alr 
Alanine racemase [Cell wall/membrane/envelope biogenesis]
Alanine racemase is part of the Pathway/BioSystem: Mureine biosynthesis
Statistics
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PSSM-Id: 440550
Aligned: 943 rows
Threshold Bit Score: 102.878
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4Y2W_A         7 RPTRVEVYLDAITHNFREIKKIVgK-NVKIMAVIKGDAYGHGASYVAK-FLEKEgVDYFGVATTEEALEL----REK--G 78 
WP_011275804   1 mtAIWSVDKEAFLQNAIKVKN-----GNSIMAVVKNNAYHYGLEFAVT-SFLKAgINTFSTTSLKEAIKV----REI--A 68 
WP_102244628   4 R-SRLVVNLDHFAYNINQIRKIS-P-KAQILCMIKADGYGHGMIPMARyAITEMgIREFGCATIGEALKL----REElnE 76 
WP_014245335   4 R-SRHFISFEKLENNYKKLKEIC-V-DNKIIFMVKANAYGHGVIPIVRhSVEKLgITEFGCASLGEALLL----REElyD 76 
NP_603388      3 TSFYVSLDKNALYHNIEYLREY--K-QKELLPVIKANAYGHNYLLIAK-ALYDFnIKTWAAARFSEAITI----TEYm-- 72 
WP_046790320   1 mgGILTIDRKQFIETAKKSAG-----GRNVIAVVKNNAYNYGLEFAVK-AFGEAgIHSFATTSLDEAKRI----RMY--A 68 
WP_012656959   1 mtARWTVDRTKFIENVKSVID-----NTPVMAVVKNNAYHYGLEFAID-AFLQAgITTFSTTNLNEAILI----RKI--A 68 
WP_000127595   1 mtATWSVNKKIFLQNAITVKN-----NQPLMAVVKNNAYHYDLEFAVT-QFIHAgIDTFSTTSLREAIQI----RQL--A 68 
WP_004263632   1 -mATIELNYNNIRQNAINLKE---Q-AQDIIAVVKNNAYNLDLRECVK-LYSEVgINYFATTKEEECKVI----RETl-G 69 
WP_123827392   5 NNLYLRISLDTIKSNIRKLTKQL-PyRSSLFMVCKNNVYGFGMSLLSH-LANEn--lSFVLNDWRDYQRFvqivRD---- 76 
4Y2W_A        79 iK--T----PILIFGYTPP---TQ---LRQIVKHD-LTQTVYDIKYAKELEKEslKQNKRA-KVHIKIDTGLGRIGyIDF 144
WP_011275804  69 pD--A----TIFLMNAV-----YD---FEKVRHYQ-IQMTLPSLAYYYKYKNDl----SGI-KVHLEFENLLHRSG-FRT 127
WP_102244628  77 lE--F----DIYVFSDIQLellEN---ADIYLKRR-IIPVISNVSELDYILHTpe--fRHF-PICLKFNTGMNRLG-LDP 142
WP_014245335  77 lE--F----EIYVFSDVQVe-lREc--AEIYLNRR-IIPVISNRDDLDFILNs--REfENF-PLFIKFNTGMNRLG-LEM 142
NP_603388     73 mNnfSindfKILVFESLd----DD---YSFLEKYPqICPTINSIKDLKNA--La-N-NiPIdRLSLKIDFGFGRNG-IKT 140
WP_046790320  69 pD--A----LIFIMNPV-----RN---FEAVYEYD-LHVTLPSPEYYYEHQEAl----SGV-NVHLEFAGLFNRSG-FED 127
WP_012656959  69 pE--A----TIFLMNPV-----TR---FNDLRQYN-IQMTLPSLAFYHRYQSEl----DGI-SVHLEYENLLHRSG-FKT 127
WP_000127595  69 pD--A----TIFLMNAV-----YE---FDLVREHQ-IHMTLPSLTYYYNHKNDl----AGI-HVHLEFENLLHRSG-FKD 127
WP_004263632  70 kE--A----NIFLLNPT-----YD---FALAREYN-IEINIASLEYLKENIEKl----KDL-TLQLEFAGSMRRAG-AKN 128
WP_123827392  77 -S--K----PVLILYPVLN---DDpwiLTQLGEHSnLYITVMKKEDWAFVl----RKGYEA-KSYVRIDPFLGLHG-LSK 140
4Y2W_A       145 -DLAQKEILE---MANMRGLI-LEGIYSHFAAASED--D---RDYCKEQFDKFMNLIS-SLEkkrlkiPlKHI-ANAAAI 212
WP_011275804 128 lEEIREVLNDhhiNSNEDKMI-ISGLWTHFGYADEF--D---VPEYSIEREAWLNIVD-TLLdegyhfDlIHA-QNSASY 199
WP_102244628 143 -NDTPLIVNK---LKQHGRNS-VHHLISHYANASS---DmnaHEVNVLQRTRFGEIKK-FFRdsgitlErTSQ-SNSGTI 212
WP_014245335 143 -DKVDEVIRS---IRVSGRKS-IYHLMTHLSSSSLPikK---NKRNIIQFENFEKIKK-AFSdagievErTSI-ANSGAI 212
NP_603388    141 -EEVDEL-KN---LIKFNSLK-FLGIFSHLFSSTYT--D------GLEVIRKFTEVVN-KLGkd--nfEmVHL-QNAAGI 202
WP_046790320 128 aSAMIEVLEHqksLDAGKRMN-IKGIWTHFGYADEL--D---MDEYGIERGMWQELLN-MLNeaghtfEiIHA-QNSASF 199
WP_012656959 128 fEEMKTVIDDnnqLPVHLQMN-INGIWTHFGYADEF--D---VIEYEIEKESWLKGLK-WISryh-tfEmIHS-QNSASF 198
WP_000127595 128 lNEIKEVLKDhhhNQNA-KMI-ISGLWTHFGYADEF--D---VSDYNVERSQWMEIVE-ALLsegyqfDlIHA-QNSASF 198
WP_004263632 129 lEEVLEIIa----FCKENDLK-LKGFWSHFSFADEF--D---G-FYEKEKELVLNVLDeALKny--dfEvVHL-QNSASF 194
WP_123827392 141 -EEAMSLP----------KVHaCKGVLIHLNESI-----------NAKEEAVINEIYQwT-Kkn-----nMSMnIGGSNI 192
4Y2W_A       213 -----LNLN-----Y-SHLD--MVRPGIILFGAYPSk------Rv-eRKV---EL-RETL-RFTTRVVHLKDVPAGFFIG 267
WP_011275804 200 -----YR-EgqkllP--HHT--HARVGIALYGSRPYs------Al--NEY---SI-KQSL-TVKGNVIQVREVNAGDNCG 256
WP_102244628 213 eqkvgL--P-----EnSD-Dt-HVRPGLMLYGPSSLn------SgvpGNF---EG-KLVS-KLETYILRTFEVKKGDVVG 272
WP_014245335 213 -----EQGA-----G-LGET--HVRPGLMMYGPSSMl-----pQy--SDLslwSG-EIIS-KLETYVISIFDVEKGQPVG 270
NP_603388    203 -----YNYN-----V-EVVT--HIRTGMLTYGLQEAg------F---YDH---DL-KPVFtGLIGYVDSVRYVNELDYVA 256
WP_046790320 200 -----AR-Dgl--lD--GHT--HLRLGISLYGSRPYs------Il--PEA---DY-MQSL-ELKAEIVQIRNIKADQRCG 254
WP_012656959 199 -----IR-Dki--fD--EHT--HVRIGIILYGSRPYa------Sl--DES---VT-HQSL-TVSANVIQVRNISKGESAG 253
WP_000127595 199 -----YR-EgqillP--HHT--HARVGIALYGSRPYs------Sl--NQH---DI-VQSL-TVKAHVIQVREVQAGDYCG 255
WP_004263632 195 -----LR-Dgv--fE--KTT--HQRLGIILYGAMPYdvnvnlvAl--ENL---VI-KNPI-TVYGEIINIVKLNKGECIG 255
WP_123827392 193 -----INKP-----N-LHFPflEVRLLMELLGS--------------RNR----VtEPCL-ELHARILSKTLIREPIHVG 242
4Y2W_A       268 YGKSF-VTKRK-SVIATIPVGYA--DGLDRRLSNnY-KLLLKGKYVPIVGRVCMDQCMIDV--TDVEG--V--EIGDEVV 336
WP_011275804 257 YSFAF-EATRDhTRLAVVDVGYG--DGILKSRAk-H-EALIKGKRYPIRA-LMMSHMFVEV--DE--E--V--DAQDEVI 322
WP_102244628 273 YNST--PCPED-GLIAILAIGYG--DGFFNRYSG-A-HLYHKGFEGVIIGRVSMDMTHVFF--PKEASdhI--RAHEIFT 341
WP_014245335 271 YGAT--PCPSK-GKVAIVALGYG--DGFTTRYIG-T-HLYHKDIKGKVVGRVNMDMAQVFFdeNSLPD--L--KVGDSFT 339
NP_603388    257 YEDLTsISPKT-KKIAKIKIGYG--DGFPKANNk-T-TCLIK-KKEYVISQVTMDNTFIEV--DD--R--V--NVGDKVH 322
WP_046790320 255 YGGSY-EPGHD-SRIAVVDIGYG--DGVLRKRAa-F-DCLINSRRYPIKS-LMMSHMIVEI--DD--D--V--SIGDEVI 319
WP_012656959 254 YSFAF-TAEKE-TKLAVVDIGYG--DGILRTRSk-H-DCIIKGRRYPIRA-LMMSHMFVEV--DN--T--V--EAEDEVI 318
WP_000127595 256 YSFAF-EVTKNnTKLAVVDIGYG--DGILRTRAk-H-EALINGKRYPIRA-LMMSHMFVEV--DG--N--V--HAQDEVI 321
WP_004263632 256 YSNSY-IADVD-KKVGIVNIGYG--DGILRDRLk-GkTCIINGKNRNIYS-TMMSHLVVEI--GE--E--E--QIGDRVY 321
WP_123827392 243 YTSSR-VKLSK-GTCLLVAIGYGdfPSFAQMFENqT-PIFIERKKFVLPCYPCMNTSWLYC--EE--E--VfiR-RESIV 312
4Y2W_A       337 IIGT-QnnetVSVESMA-DKIETIPQEVFSRIS-R--RVPRVY-FY 376
WP_011275804 323 LYNN-D----IRIDEYTfKGVGANSEQ-LSAMNhD--SLIKEY-R- 358
WP_102244628 342 IWGAkDg----DLQSFC-SETKIIPYEVFCALL-P--RVPRVYrLn 379
WP_014245335 340 LWDH-Sa---eRFAEFC-KEAKIIPYEVFIGIT-Q--RVPKIY-S- 375
NP_603388    323 LYHR--------PNEMK-TRTGLSMLEALIALS-Pl-RVKRIF--E 355
WP_046790320 320 LYND-E----MRIDEFTaKGVGANSEQ-LGALNyQ--SLKKVI-LN 356
WP_012656959 319 LYSD-E----IRIDEFTfKGIGANSEQ-LSALNhQ--SLIKEY-IN 355
WP_000127595 322 LYNN-D----IRIDEYTfKGVGANSEQ-LSAMNhD--SLKKEY-IS 358
WP_004263632 322 VYDD-Kq----QLHDYT-KYFGPNSVQ-LAALNyDslKVKKIY--- 357
WP_123827392 313 LFDKfN-----SIHKLA-LNLSVDVDEIYSSLS-Pl--IYRHY-V- 347
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