Conserved Protein Domain Family
SSM4

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COG5183: SSM4 
E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 227510
Aligned: 3 rows
Threshold Bit Score: 1123.89
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
730835     22 EETDTATFNDDApsgATCRICRGEATEDNPLFHPCKCRGSIKYMHESCLLEWVAsknidiskPGADVKCDICHYPIQFKT 101  baker's yeast
19074333    1 MEKENTPMNEEK---RSCKICHTGDIRGDELCNPCRCSGTIKYIHRECLMSWME--------CSGTKKCDICHYEYKFKD 69   Encephalitozoon c...
19113525    1 -------MNADD---EICRVCRCEGAPDSPLFHPCKCTGSIRYVHQECLVEWLG--------HSKKTHCELCKAKFEFTK 62   fission yeast
730835    102 IYAENMPEKIPFSLLLSKSILTFFEK----ARLALTIGLAAVLYIIGVPLVWN---MFGKLYTMMLDGSSpYPGDFLKSL 174  baker's yeast
19074333   70 IYKPDTPQILPVSIIIRGVADVGWKA----TIVLT----WCILQMVKWMGVFY------------------FN--GYLFA 121  Encephalitozoon c...
19113525   63 VYSESMPRTIPFTILCRKLASTLKQRviffTRVLLTFFCWTVLLPLIFKHVWNlnfKIGDTYTIHARNKT-FTAPQKPGY 141  fission yeast
730835    175 IYGYDQSAT-PELTTRAIFYQLLQNHSFTsLQFIMIVILHIALYFQYDMIVREDVFSKMVFHKIGP--RLSPKDLKS--- 248  baker's yeast
19074333  122 VSTGLCDTD--------G-----G-SGFR-NSLIWLGVGIPLTWLAQ--VNR--CLLNQIREKFGE-----D---MR--- 171  Encephalitozoon c...
19113525  142 FESISQITSsPRLNTLIANTAEGQVLTFV-VTFILITAFLVREWVLQNAVQVADELQGQQFENVNQnnQAQAAAAAAqnl 220  fission yeast
730835    249 R----LKERFPMMDDRMVEYLAREMRAHDEN---------RQEQGHDRLNMPAAAADNN----NNVINPRNDNVPPQDPN 311  baker's yeast
19074333  172 R-----RRRMLMNPRAILESISRESAQLERSt-------aVPQGEHAREIGRDLSSDSN----------VS---TSREMA 226  Encephalitozoon c...
19113525  221 RevreARQRLAMVMEHLRERQEQRNLELQRNgsfeeieraRQRFALLGDNIREPQEEENdvdvDEIFNRQQLNQPALDLN 300  fission yeast
730835    312 DHRNFENLRHVD-ELDHDEATEEHENNDSDNSLPSGDDSSRILPGS-SSDNEEDEEAEGQQQQQQPEEEADYRDHIEPNP 389  baker's yeast
19074333  227 GSRNVEGVRPRR-SNDPMNSFLFRPIVSGISGMTLPVSFISVIYGA-SRCIPTPRIHGSFGAFLSSMGLGDLYSRLVAFG 304  Encephalitozoon c...
19113525  301 D-ANSSNSVPVEfNSLHSQNVDYRDEVDSLRPQFNVDEQSSISHSSnASENIVDGAVTQANGIESDFTRVDHEPIIVNND 379  fission yeast
730835    390 IDMWANRRAQNEFDDLIAAQQNAINRPNAPVFIPPP--AQNRAGNVDQ--DEQDFGAAVGVPPAQANPDDQGQGPLVINL 465  baker's yeast
19074333  305 VAFWAVTSCTEHARKRLGIGRIRYICIFMKIYLIILlnIFFMNLTFGLv-LHYMFGNIMNKGMYALHLDNEYSSPLKMGI 383  Encephalitozoon c...
19113525  380 DENGNNESENEEVIEEDNLNRNVIAEAQNQVVADEErnAVARAAQIAEadDADDFDGILEFLGLRGPITGFLQNCLVIAF 459  fission yeast
730835    466 KLKLLNVIAYFI--IAVVFTAIYLAISYLFPTFIG---FGLLKIYF----GIFKVILRGLCHLYYLSGAHIAYNG---LT 533  baker's yeast
19074333  384 SFIFHMSIGYTF---SIVIRNIFLRFKRCFRPGVLh--FIPDDEDS----RMDELYEASKIGVSRILLRLVGYLA---FF 451  Encephalitozoon c...
19113525  460 VVSVFLTTAVGIpyMSGRLMVEWILFIIHRPTFILrfiLSFVNILFdwtvGGAFNIVKILTKLPLLSTVFVKLKLqgiFS 539  fission yeast
730835    534 KLVPKVDVAM-SWISDHLI----HD----IIYLYNGYTENTMKHSIF--IRALPALTTYL----------------TSVS 586  baker's yeast
19074333  452 TLFYGAGLMViRCACGEMG----------IRFSVRSFLKLSLSYKTF--TMLLYSNKIFCd---------------YVVK 504  Encephalitozoon c...
19113525  540 SSFQQVSNNMySWIYDHVFsssdHAyeslIYYMKTGHKQVVQSFSIFpvFRVCQMFAVILkdfvenysnrpvdrvfTTLI 619  fission yeast
730835    587 IVCASSNLVSRGYGRENGMSN-PTRR---LIF-QILFALKCTFKVFTLFFIELAGFPILAGVMLDFSLFCPILASNSRML 661  baker's yeast
19074333  505 GLNKVVRLEARMLGMENFLYNaQMER-----Y-DKQMLMWCANKNKIFRRQHIKAREGRRPTEREICKYFNTHPSSDFAI 578  Encephalitozoon c...
19113525  620 GYCMFTFLGISYLNRKQFLFNdPQIRnveLAFrEVLRQCGSIAKFGIIFSIELVVFPIFCGILLSMCLIGTFKKLAAENL 699  fission yeast
730835    662 WVpsICAIWPPFSLFVYWTIGTLYMYWFAKYIGMIRKNIIRPGVLFFIRSPEDPNIKILHDSLIHPMSIQLSRLCLSMFI 741  baker's yeast
19074333  579 FY--VPKLFGLRCSLIITSVVLCFYGLYTGYMVIAKHIMERINAEAYIRDSGD--------VLLYLILAFLFRLSWIVIH 648  Encephalitozoon c...
19113525  700 LN--VMTVYPAQSIFLAWFIGITFMFEFAVFISMVRK-IVRPGVLYFLRDPNDPQFHPIREILEKPMLFQLKKIGFSAIL 776  fission yeast
730835    742 YAIFIVLGFGFhtrifFPFMLKSNLLSVPEAYKPTSIIswkFNTILLTLYFTKRILESSSYVKPLLER--YWKTIFKLCS 819  baker's yeast
19074333  649 VAMSGIRGEKS--------MLQTAGELCKHGIVNVYIN-----TVYPLFGSLMVIVLSNDGTSISEMR------PLRLFL 709  Encephalitozoon c...
19113525  777 YFAFIIGCVGS-----VIHLLKSTGIIFPIEFTTKPAV---FEAPIDLLALEILIFLSIKLFKPLELTrsFWRTLVSTFC 848  fission yeast
730835    820 RKLRLSSFILGKDTPTERGhiVYRNLFYKYIAAknaewsnqeLFTKPKTLEQAEElfGQVRDVHAYFVPDGVLMRVPSSD 899  baker's yeast
19074333  710 FFFSSTSIVETILSSSPEN--YT---FRALIRE---------------------L---CKINAFISVVFGIWYMYNAVTL 760  Encephalitozoon c...
19113525  849 RCLRLSSYVMGQRYSDEEG--YYPKQYFSFLRR---------IISKPSDTENQDD--GDKQKAKKDFVQDGFFLWCPSKD 915  fission yeast
730835    900 IVSrNYVQTMFVPVTKDDkllkpldLERIKERNKRaagefgylDEQNteyDQYYIVYVPPDFRLRYMTLLGLVWLFASIL 979  baker's yeast
19074333  761 LLG-LSNGEFAVLSVVVG-------YTIFVSKKIG----------QS----IQSDK----GFYKRLLDENYLVERRVVNI 814  Encephalitozoon c...
19113525  916 VVP-VRQGAMLIPVTENG-------YEIFGEKKK---------VEEN---ADYTITYAPSNFYKRLIALLLFCWICSTLV 975  fission yeast
730835    980 MLGVTFISQALINFVCSFGFLPVVKLLLgernkvyvawkelsdisYSYLNIYYVcvgsvclskiakdiLHFTegqnTLDE 1059 baker's yeast
19074333  815 DEE----------------------------------------------------------------------------- 817  Encephalitozoon c...
19113525  976 TVLLVFVPLSLGRAIYAWCFPNVVKHDF-----------------YAYAIGFYS--------------ISFP----MYAI 1020 fission yeast
730835   1060 HAVdeneVEEVEHDIpERDINNApvnnINnveegQGIFMAIFnsifdSMLVKYNLMVFIAIMIAVIRTMVSWVVLTDG-I 1138 baker's yeast
19074333      --------------------------------------------------------------------------------      Encephalitozoon c...
19113525 1021 HAS----VKFLKLDY-LRSLMNK----LN-----LKIVMRSL-----VMALKYLLLAFLGIFILPLLLGAIWELYVAIpF 1081 fission yeast
730835   1139 LACYNYLTIRVFGNSSYTIGnskWFKYDESLLFVVwiiSSMVNFGTgyKSLKLFFRNRntsklnFLKTMALELFKQGFLH 1218 baker's yeast
19074333      --------------------------------------------------------------------------------      Encephalitozoon c...
19113525 1082 RTIFNRGTLALDAFQNWVIG---LFMLRMIYFTVT---SNEERFVS--RLFQDAFRDR------WTNPQILPLLKNVLIP 1147 fission yeast
730835   1219 MVIYVLPIIILSLVFLrDVSTKQIIDISHgSRSFTLSLNESFPtwtrmqdIYFGLLIALESFTFFFQATVLFIQWFKSTV 1298 baker's yeast
19074333      --------------------------------------------------------------------------------      Encephalitozoon c...
19113525 1148 FTSALIAAVVLPSVFT-YVTYPFLSSIFP-SASKTLMYRLMHP-------IFLALLGLALLGRRFVETSSKWSQGIRDDL 1218 fission yeast
730835   1299 QNVKDEVYTKGRALENLPDES 1319 baker's yeast
19074333      ---------------------      Encephalitozoon cuniculi
19113525 1219 YLVGTRLHNFGESAPPAISES 1239 fission yeast
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