Conserved Protein Domain Family
SUN

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pfam03856: SUN 
Beta-glucosidase (SUN family)
Members of this family include Nca3, Sun4 and Sim1. This is a family of yeast proteins, involved in a diverse set of functions (DNA replication, aging, mitochondrial biogenesis and cell septation). BGLA from Candida wickerhamii has been characterized as a Beta-glucosidase EC:3.2.1.21.
Statistics
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PSSM-Id: 427547
Aligned: 167 rows
Threshold Bit Score: 299.06
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003842310 1158 NNKIPCNEFPY--GYGALPIAHEGLGGWSGIQDpqysgsdgfddittiVKGScseGSCCTAGRFCSYGCPNPYLKLSFPK 1235
ESW96062      151 DGTISCSSFPS--GQGVIALDWLGFGGWSGIYHp--------------SDTSt--GGSCTEGSYCSYACQPGMSKTQWPS 212 
Q6C3M7        158 DGTIDCGDFPS--GQGVIALNQLGFGGWSGIYHp--------------GSTAt--GGNCAEGAYCSYACQSGMSKTQWPD 219  Yarrowia lipo...
Q6BKL4        150 DGTISCSDFPS--GQGVVSLDHLGFGGWSGVEN---------------SDGSt--GGNCKEGAYCSYACQSGMSKTQWPS 210  Debaryomyces ...
CCE80263      178 DGTISCSDFPT--GQGVIRLDHLGFGGWSGIEN---------------SDGSt--GGHCKEGSHCSYACQAGMSKTQYPS 238 
XP_002616690  188 DGVLSCDEFPS--GQGVIALDHMGFGGWSGIYN---------------SDTSt--GGSCKEGSYCSYACQSGMSKTQWPS 248 
EER34126      161 DGVLSCDEFPV--GQGVIALDHLGFGGWSGIYN---------------SDTSt--GGSCKEGSYCSYACQSGMSKTQWPE 221 
XP_011276073  164 DDTIDCTDFDSlvGQGVIALDNLDFGGFSGIYHp--------------SDTSt--GGSCKEGAYCSYACQPGMSKTQWPS 227 
XP_003646971  196 DGVVPCKQFPE--GEGVVSLDWLPFGGWSGIEH---------------PDTSt--GGKCTEGAYCSYACQAGMSKTQWPS 256 
Q755Z5        180 DGVVPCSEFPE--GQGVVKLNWLDFGGWSGIEN---------------HDTSt--GGKCKEGSHCSYACQSGMSKTQWPS 240  Eremothecium ...
XP_003842310 1236 KQGRTGQSVGGLFCnNNGYLEMADGSlGKTLCGQSSSSMTvrVQNNLSKSVSICRTDYPGTESMTFPLTLGPGQS-GFLA 1314
ESW96062      213 DQPSDGKSVGGLYC-KGGKLYRSNQD-SDYLCEWGENSAR--VVSKLDKSVAICRTDYPGTENMVIPTVVEAGGE-NILT 287 
Q6C3M7        220 EQPANGVSVGGLLC-KGGKLYRSNQQ-SDYLCEWGTQSAI--VTSSLDKEVAICRTDYPGTENMVIPTVVEAGSSgVPLA 295  Yarrowia lipo...
Q6BKL4        211 NQPLNGVSIGGLLC-KGGKLYRSNKD-QNTLCAWDENKAS--VVNNLSKTVAICRTDYPGTENMVIPTVVDGGSS-SPIS 285  Debaryomyces ...
CCE80263      239 KQPGSGVSIGGLLC-KNGKLYRTNTN-STHLCEWGENKAR--VVSELSDTVAICRTDYPGTENMVLPTVVEGGDS-SILT 313 
XP_002616690  249 NQPSNGVSVGGLQC-KNGKLYRSNPN-SKYLCEWGVDKAV--VVSKLSQDVAICRTDYPGTENMDIPTVASAGQT-TVLT 323 
EER34126      222 DQPSNGVSVGGLLC-KNGKLYKTNSR-SNYLCEWGVNKAN--VVSKLSKSVAICRTDYPGTENMVIPTVVDGGSS-SVIT 296 
XP_011276073  228 SQPGNGVSVGGLVC-KNGKLRRSNTD-QKYLCEWGVDAAY--VKNELSKDVAICRTDYPGTENMVIPTYVQGGKT-LPLT 302 
XP_003646971  257 EQPEDGRSVGGLLC-KNGYLYRSNKN-TDYLCEWGVDKAD--VINKLDDVVSICKTDYPGCENMVVPTVVEPGKS-LPLT 331 
Q755Z5        241 EQPEDGRSIGGLLC-KNGFLHRTNKN-TDYLCEWGVDKAE--VVNKLDKVVSICRTDYPGTENMVIPTIVNPGKT-MPLT 315  Eremothecium ...
XP_003842310 1315 SPDQGKYYFWQGKATSAQYYVNKQGVSESDACTWGKPMGGVGNWSPTILGTSWDDVKAnegFTSLFQNtESPNERLDYDI 1394
ESW96062      288 VVDQDTYYQWQGKKTSAQYYVNNAGVSYQDGCIWSEAGTTVGNWAPLNFGAGYTNGIS---YLSLIPN-PNNREAANFNV 363 
Q6C3M7        296 VVNQDAYYTWMGKPTSAQYYVNNAGVSYQDGCLWGTSSGDVGNWAPLNFGAGAAGGIS---YLSIIPN-PNNRNSANFNV 371  Yarrowia lipo...
Q6BKL4        286 VVDQSTYYKWKGGSTSAQYYVNNAGVDWTDGCVWGTSGSGIGNWAPLNFGAGYDNGIA---YLSLIPN-PNNKDSLNFKV 361  Debaryomyces ...
CCE80263      314 VVNSETYYEWKGKPTTAQYYVNDAGVPWTTGCTWGHSGSGYGNWAPLNFGAGYSNGVA---YLSLIPN-PNNKKPLNFKV 389 
XP_002616690  324 TVDQDSYFQWQGKKTSAQYYVNNAGVSWEDGCTWGSAGSGIGNWAPLNFGAGYTGGIG---YLSLIPN-PNNYDAANFNV 399 
EER34126      297 VVDQDTYYTWRGGATSAQYYVNNAGVAWKDGCLWGTAGSGVGNWAPLNFGAGYADGVA---YLSLIPN-PNNYDSLNFNV 372 
XP_011276073  303 VVDQSTYYQWGGKGTSAQYYVNDAGVSYEKGCVWGSEGSGIGNWAPLNFGAGAVNGIS---YLSLIPN-PNNNNALNFNV 378 
XP_003646971  332 VVNEDTYYKWRGLKTSAQFYVNDAGVPVEEGCVWGTEGSGIGNWSPLNFGAGYIDGIA---YLSLIPN-PNNRKPLNFKV 407 
Q755Z5        316 VVDEDTYYKWRGLKTSAQYYVNDAGVSMEDGCIWSDEGSTVGNWAPMNFGAGYVDGIA---YLSLIPN-PNNRQPLNFNI 391  Eremothecium ...
XP_003842310 1395 TF----TGDGVVSPCAYKraSGQYCqGsKCsddiKGGCT 1429
ESW96062      364 KIvaydDDSVVSGECYYE--NGSYN-G-DG----SDGCT 394 
Q6C3M7        372 EIia-tNGATVNGKCVYE--NGKYN-G-GD----SNGCT 401  Yarrowia lipolytica
Q6BKL4        362 KIva-dGDSTVSGDCTYE--NGKYN-G-DG----TDGCT 391  Debaryomyces hansenii
CCE80263      390 KIvpdgDDSVVSGNCTYA--DGKYN-G-DG----TNGCT 420 
XP_002616690  400 KIts-yNGGTVNGECVYE--NGSYN-G-NG----SDGCT 429 
EER34126      373 KIva-qDGASVSGSCVYK--DGKYN-G-NG----SDGCT 402 
XP_011276073  379 KIvaadDDSVVSGDCKYE--NGKYL-N--G----QDGCT 408 
XP_003646971  408 KIvaadAHSVVSGECYYE--NGLYN-G-YS----KDGCT 438 
Q755Z5        392 KIvpadKNSVISGDCWYE--NGRYN-G-HG----TDGCT 422  Eremothecium gossypii
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