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SH2: Src homology 2 (SH2) domain
In general, SH2 domains are involved in signal transduction; they bind pTyr-containing polypeptide l...
View in Cn3D
iSH2_PI3K_IA_R: Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
PI3Ks catalyze the transfer of the gamma-phosphoryl group from ATP to the 3-hydroxyl of the inositol...
View in Cn3D ProteinSuperfamily MembersPubMed
iSH2_PIK3R3: Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
SH2_nSH2_p85_like: N-terminal Src homology 2 (nSH2) domain found in p85
Phosphoinositide 3-kinases (PI3Ks) are essential for cell growth, migration, and survival. p110, the...
SH2_cSH2_p85_like: C-terminal Src homology 2 (cSH2) domain found in p85
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