Conserved Protein Domain Family
PLN02980

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PLN02980: PLN02980 
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding
Statistics
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PSSM-Id: 215530
Aligned: 5 rows
Threshold Bit Score: 2953.87
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
225425019    4 GEFDEDFVVESCIVRSLSPALTLKQGLEKIKDAVEELKLNPPC-SRSGLYRFQASRrytkqdAIESRGKKYVGGNPSIDH 82  
145337303   68 VNLDDDLVVQVCVTRTLPPALTLELGLESLKEAIDELKTNPPK-SSSGVLRFQVAV------PPRAKALFWFCSQPTTSD 140 
242062128   65 ENGDRDLPVDVSFTRRLPPALTVGDGLDALLRAANEVKATPPAgARSGVIRFEVLV------PPSTKALKW-CSQFRGSS 137 
255546995   71 ADKDCEVVIETCITRTLTPALTLEHGLRSVKEAVEELKLNPPA-SSRGILRFQVAV------PPSPKALNWFLCQPESSG 143 
297838661   70 VNLGDDLMVQVCVTRTLPPALTLELGLESLKEAVNELKTNPPQ-SSSGVLRFQVAV------PPSAKALFLFCSQPTSSD 142 
225425019   83 WKVVKKVLRYLQGTKDYMLTYRRTNNLEIIGY-------SDFDYAGYKDTRRYLSIDSTCVTAYGFMNANFNEESSsMRH 155 
145337303  141 VFPVFFLSKDTVEPSYKSLYVKEPHGVFGIGNafafvhsSSVDSNGHSMIKTFLSDESAMVTAYGFPDIEFNKYST-VNS 219 
242062128  138 LFPQFYLSRKLTSAPSFQL------EICGIGSaic-frgSYLVKNEFDLVSRYISSESHLIKAYGFVDMNYDKESSlVEE 210 
255546995  144 VFPLFFLSKETENVSRKSLYLNRSRGVFGIGAaiyfmdsSSSMSGEQRRIRRYVSSDSIRIATYGFMDTKFDTLTYsIKN 223 
297838661  143 VFPVFFLSKETLEPSYKSLYVKEPHGVFGIGNalsfvhpSSIDSKGHSMMKTFLSDESAMVTAYGFPDIEFNKYST-VNS 221 
225425019  156 EAGSFYIFIPQIELDEDEGISILSATLAWSDSPLSTFEESIHSYELSLYQL----WLTEILMWDSLFLLPKAiHKGVGEI 231 
145337303  220 KDGSSYFFVPQIELDEHEEVSILAVTLAWNESLSYTVEQTISSYEKSIFQVsshfCPNVEDHWFKHLKSSLA-KLSVEEI 298 
242062128  211 KLGSYYFFIPQVELSEFDSCSILSSTLVWDDSMSHTFEDAVSLFESCFNQIqnsyDSSASISHKGLVPSYISgDAHLSET 290 
255546995  224 EAGSFYLVVPQIELHEHEDVSVLSATLAWDDAFFCTFKQAIQSFESSIYQAsyhcWPTRDRIHSYCMRSALN-------- 295 
297838661  222 KGGSSYFFVPQIELDEHEEVSILAVTLAWNESLSYRFEQTISSYEKSIFQVsshfCPNLEDHWFKHLKSSLA-KFSVEEI 300 
225425019  232 EAESLVYMKASSLSEKGIEADLMELETPFSCQFCIRLSPTVTAASNM--LDHSGERTFSSQDYANINALWASLIIEECTR 309 
145337303  299 HPLEMEHMGFFTFSGRDQADVKELKSIQSSCQFHCKLSPDVVFSNNM--LNRETEVSNFLRDEANINAVWASAIIEECTR 376 
242062128  291 GNAQLVYLDTEVLASIDAKASVQKENFLTSDRSFVRFSPQLFLYSNMelYLQRNTIESFIKSCSNINLAWASLIVEECVR 370 
255546995  296 -------------------------------------KGSLVKDDTFqmLDHVGGTNYSWQDYANINAVWASLIVEECSR 338 
297838661  301 HPIEMEHMGFFTFSGRDQADVKELKSIQSSCQFHCKLSPDVVFSNNM--LNRETEVSNFLKDEANINAVWASAIIEECTR 378 
225425019  310 FGLMYFCVAPGSRSSPLAIAASTHPLTTCIACFDERSLAFHALGYARGSHKPAVVITSSGTAVSNLLPAVVESSQGFVPL 389 
145337303  377 LGLTYFCVAPGSRSSHLAIAAANHPLTTCLACFDERSLAFHAIGYAKGSLKPAVIITSSGTAVSNLLPAVVEASEDFLPL 456 
242062128  371 LGFTYFCIAPGSRSSPLALSATGHPLTKCISCYDERSLGFHALGYGRGSRKPAVVITSSGTAVSNLLPSVVEASQDFVPI 450 
255546995  339 LGLTYFCIAPGSRSSPLAIAASVHPLTTCVACFDERSLAFHAVGYARGSQKPAVVITSSGTAVSNLLPAVVEASQDFVPL 418 
297838661  379 LGLTYFCVAPGSRSSHLAIAAANHPLTTCLACFDERSLAFHAIGYAKGSLKPAVIITSSGTAVSNLLPAVVEASEDFLPL 458 
225425019  390 LLLTADRPPELHDAGANQAINQVNHFGSFVRFFFGLPVPTDHIPARMILTTLDSAVYWATSSPCGPVHINCPFREPLENS 469 
145337303  457 LLLTADRPPELQGVGANQAINQINHFGSFVRFFFNLPPPTDLIPVRMVLTTVDSALHWATGSACGPVHLNCPFRDPLDGS 536 
242062128  451 ILLTADRPPELHDAGANQAINQVNHFGTFVRYFFNLPPPGDQIHARMVLTTLDSAAYYAMQAPQGPVHINCAFREPLDYT 530 
255546995  419 LLLTADRPPELQNAGANQSINQVNHFGSFVRCFFSLPAPTDSIPARMVLTTLDSAVHWATSSPYGPVHINCPFREPLDDS 498 
297838661  459 LLLTADRPPELQGVGANQSINQINHFGSFVRFFFNLPPPTDLIPVRMVLTTVDSALHWATGSACGPVHLNCPFRDPLDGS 538 
225425019  470 PKEWMLSCLKGLDSWMSSAEPFTKYIQLQHS-HAPDDSQGQMAEVIEVIQGAKRGLLLIGAITTEDDIWAALLLAKHLCW 548 
145337303  537 PTNWSSNCLNGLDMWMSNAEPFTKYFQVQSH-KSDGVTTGQITEILQVIKEAKKGLLLIGAIHTEDEIWASLLLAKELMW 615 
242062128  531 NQHWNVDCLRGLDKWFKNSEPYTRYLRMKTV-SAFGNYSCSVMEVLEIIEKAEQGLLLVGAIHTDEDMWAVALLARHLSW 609 
255546995  499 PDKWMFSCLKGLDIWMSSAEPFTKYIEMPSSlPCDGDNRIALIQILEIVQRAKRGLLLIAAMHTEDDIWAALILAKHLNW 578 
297838661  539 PTNWSSNCLKGLDMWMSNAEPFTKYFQVQSH-KSNGVTTGQITEVLQVIKEAKKGLLLIGAIHTEDEIWASLLLAKDLMW 617 
225425019  549 PVVADILSGLRLRKLSTSFQEiEDNVLFLDHLDHALLSDFVRVWAQADVIIQIGSRITSKRISQMIEDCFPCSYIMVDKH 628 
145337303  616 PVVADVLSGVRLRKLFKPFVE-KLTHVFVDHLDHALFSDSVRNLIEFDVVIQVGSRITSKRVSQMLEKCFPFAYILVDKH 694 
242062128  610 PVATDILSGLRLRKVVNSLPGfDKNILFIDHIDQILLSDSAKNWISPDVILQIGSRITSKRVGMFLETSFPSSYILIDRH 689 
255546995  579 PVVADILSGLRLRKLLSYFPGvEENILFVDHLDHALLSNFVRGWMQLDVVIQIGSRITSKRIFQMLEEHYPFSYILVDNH 658 
297838661  618 PVVADVLSGVRLRKLFKPFLE-KLTPVFVDHLDHALLSDSVRNLIEFDVVIQVGSRITSKRVSQVLEKCFPFAYILVDKH 696 
225425019  629 PCRHDPSHLLTHRIQSTITQFADCLCKAQFPLMSSKWSVSLRALDMMVAQEISSLIHSESFLTEPYVAHVILEALTCDSA 708 
145337303  695 PCRHDPSHLVTHRVQSNIVQFANCVLKSRFPWRRSKLHGHLQALDGAIAREMSFQISAESSLTEPYVAHMLSKALTSKSA 774 
242062128  690 PCRHDPSHIVTHRIQANVAEFAASLRRCTFQRKRSRWTEILTILNSVVSQEIMFQIHAKCSLTEPYVAHVIGESLCGDAV 769 
255546995  659 PCRHDPSHFVTHRVDCSILQFVDSLMKAKLLNRSSEWCGFLSALDRMVAWNISYQIYAENLLTEPHVLRAISEALSSESA 738 
297838661  697 PCRHDPSHLVTHRVQSNIVQFADCVLNSQFPRRRSKLHGHLQALDGAIAREMSFQISAESSLTEPYIAHMLSKALTSESA 776 
225425019  709 LFIGNSMAIRDADMYARNSADcTHRIGDTVLSLGLPFHWIRVSGNRGASGIDGLLSTAIGFAVGCNKRVLCVIGDVSFLY 788 
145337303  775 LFIGNSMPIRDVDMYGCSSEN-SSHVVDMMLSAELPCQWIQVTGNRGASGIDGLLSSATGFAVGCKKRVVCVVGDISFLH 853 
242062128  770 MFVGNSMVIRDLDMFGNGWMDyTTNGNNVMTHHLPDFVGTAVAGNRGASGIDGLISTAIGFAVGSNKHVFCVVGDISFLH 849 
255546995  739 LFIGNSMAIRDADMYGCSYENhSCRIADMVLNSELQCLGIQVAGNRGASGIDGLLSTAIGFAVGCNKRVLSLIGDVSFLH 818 
297838661  777 LFIGNSMPIRDVDMYGCSSEN-SSHVVDMMLSAELPCQWIQVTGNRGASGIDGLLSSATGFAVGCKKRVVCVVGDISFLH 855 
225425019  789 DTNGLSILSQRMRRKPMTILVLNNHGGAIFSLLPIAERTERRVLDQYFYTSHNVSIGKLCLAHGMKHLEVRTKIELQDAL 868 
145337303  854 DTNGLAILKQRIARKPMTILVINNRGGGIFRLLPIAKKTEPSVLNQYFYTAHDISIENLCLAHGVRYVHVGTKSELEDAL 933 
242062128  850 DTNGLSLLNQRAWRKPMTIIVVNNHGGAIFSFLPVAKTTSPQILEKFFYTSHDISISELCSAHRVKHFRVQTKEELHDAL 929 
255546995  819 DTNGLSILSTRLPRKPMTVLVINNHGGAIFSLLPIANRIDQRILKQYFYTSHNISIQQLCMAHSVRHLLVKTKKELEDAL 898 
297838661  856 DTNGLAILKQRIARKPMTILVINNRGGGIFRLLPIAKRTEPSVLNQYFYTSHDISIENLCLAHGVRYVHVGTKSELDDAL 935 
225425019  869 FTSQQENRDCVIEVESCIDSNAAFHSTLRKFACQAADHALNMLSKFSIPDFIFHGSFLCKIHGMEYSIYRIPLCAPPTSA 948 
145337303  934 FVPSVEEMDCIVEVESSINANAIVHSTLERFARQAAENSLGIVSASSFLHPMIKNVLLCQVSGIQYSQYRVKLCDRPTIC 1013
242062128  930 VKSNMEQVDCVVEVDNSIDSNANFHRIMSMFSNYSTSQYLAYLLEAPCLKSDVDAIPVDRIDAVECMLYRIQLSAPRTSG 1009
255546995  899 LTSQREQTDRVIEVESSISANSAFHSTLRKSACQAANHAFTVLSSLSVPFSISDGFFLCKILKMEYSLYRIQLCAPPTSA 978 
297838661  936 FVPSVEEMDSIVEVESSINANAIVHSTLERFARQAAENSLGIISTSSLLHPMIGNVLLCQVSGIQYSKYRVKLCDRPTIC 1015
225425019  949 SVNYktTTFYRDGFILILSLEGGHVGFGEVAPLEIHEEDLLDVEEQLRFLHHVIKGAKISFYLPLLKGSFSSWIWSCLGI 1028
145337303 1014 SDEF--SQFHREGFILSLTLEDGSIGYGEVAPLNSNVENLMDVEGQLQLVLHLMNEAKFSYMLPLLNGSISSWIWSELGI 1091
242062128 1010 LSD---GRFIHEGFVLKLRVDDNIVGFGEVAPIEIHEEDLLDVEEQLRFLLHRVKDSMLDF-IPLLRGSFSNWIWTSLGI 1085
255546995  979 PVDLdtNEFHREGYILSLSLEDGSVGCGEVAPIEIHKEDMLDVEEQLRFLLHVIKGTKISFSLPLLKESFSSWIWNNLGI 1058
297838661 1016 SDEF--SQFHREGFILSLTLEDGSIGYGEVAPLDSNVENLMDVEGQLQLVLHLMNGAKFSYMLPLLNGSISSWIWSELGI 1093
225425019 1029 PPSSIFPSVRCGLEMAILNAIAAQEGSSLLNILh---PYKVEEEISE----RSKRVQICALLDSNGSPLEVAYLAKTLVE 1101
145337303 1092 TASSIFPSVRCGLEMALLNAMAVRHDSSLLGIL----HYQKEENGSA----QPHSVQICALLDSEGTPLEVAYVARKLVQ 1163
242062128 1086 PPSSIFPSVKCGLEMAILNLLASQRKCSLFKVLagcdPLGRDENVIEynqnSSGSIQICALVDCNGSPMEVALAVAKLAA 1165
255546995 1059 PENSIFPSVRLGLEMAILNAIAERQGSSLLNIIq---PQRGKEEAYE-----KSNVKICGLIDSNGSPAEVAYIASSLVK 1130
297838661 1094 TASSIFPSVRCGLEMALLNAMAVRHDSSLLGIL----HYQKDENGSA----QPHSAQICALLDSEGTALEVAYVARKLVE 1165
225425019 1102 EGFTAIKLKVARRADPIEDATVIQEIRKMVGLQIELRADANRNWTYEQAIQFSSYVKNCDLKYIEEPVKDEDDIIKFCEE 1181
145337303 1164 EGFSAIKLKVGRRVSSVQDALVMQEVRRAVGVQIELRADANCRWTFEEAREFGLLVNSCNLKYIEEPVQNKDDLIRFHEE 1243
242062128 1166 EGFTTFKLKVGRRESPIEDAAALHKIREVVGYQINIRVDANKKWTYEQAVEFGSRVKSLRLEYIEEPVSSVNDLIKFCEN 1245
255546995 1131 EGFSALKLKVARRLDPIQDAAVIQEVRKKVGRQIELRVDANRNWSYEEAIQFGSLVKDCNLQYIEEPVQDEDDIIKYCEE 1210
297838661 1166 EGFSAIKLKVGRRVNSVQDALVMQEVRRAVGDQIELRADANCRWTFEEATEFGLLVKSCNLKYIEEPVQNKDDLIRFHEE 1245
225425019 1182 TGLPVALDETMDKIGETPLQKLAKFSHSGIVAVVIKPSVVGGFENAALIARWAQQQGKMAVVSAAFESGLSLSAYIQLSS 1261
145337303 1244 TGLPVALDETLDDFEECPLRMLTKYTHPGIVAVVIKPSVVGGFENAALIARWAQQHGKMAVISAAYESGLGLSAYILFAS 1323
242062128 1246 SVLPVALDETIDNLKGDIIPKLHQFVHPGIVALVIKPSVVGGFENAAHIAKWAQLHDKMAVISSTYESSIGLASYIQLAH 1325
255546995 1211 SGLPVALDETIDKFCENPLHMLVKYAHPGIVAVVIKPSVVGGFERAALIAEWAHQLGKMAVVSAAFESGLGLSTYIQFSS 1290
297838661 1246 TGLPVALDETLDDFEECPLRMLTKYTHPGIVAVVIKPSVVGGFENAALIARWAQKHGKMAVISAAYESGLGLSAYILFAS 1325
225425019 1262 YFELQSAEICKLMNKQLVPSVAHGLGTYRWLKEDVTFEPLSINRSQDSGFIEASVVDADRILQKFQINRDTIIRIFSEEQ 1341
145337303 1324 YLEMENVKASTEQKQGTPPSVAHGLGTYRWLSEDVMMNTLGIFRSPYSGFVEGFIADASRNLKDVKINNDVIVRTSKGIP 1403
242062128 1326 YVDQQNSIVSRIRNKVTCRAAAHGLGTYQWLREDVSEQKLKIHASPLGDGIRASVEDAHGYLHHLNINDDKIQRTYGEEK 1405
255546995 1291 YLEVQNADLCRVMDRKLGPPVAHGLGTYQWLKQDVTTKPLRIRHLP-CGFIGASVSDAIEFVQKFQINQKVICRTFTGEQ 1369
297838661 1326 YLEMVNVKASTEQKQGTSPSVAHGLGTYRWLSEDVMMNTLGIFRSPYSGFVEGFVADASINLKDVKINNNVIVRTSKEIP 1405
225425019 1342 VYTHQLAVDS-DGFSCLLNVHEIGASIENDVVVFLHGFLGTGGDWIATMKAISGSARCISIDLPGHGGSKIQNHdGKEDV 1420
145337303 1404 VRRYELRVDV-DGFSHFIRVHDVGENAEGSVALFLHGFLGTGEEWIPIMTGISGSARCISVDIPGHGRSRVQSH-ASETQ 1481
242062128 1406 LRSYSIQVDVdDDCSYLVKLREAGDHTNEKVVLLLHGFLGTSEDWIPMMNALAPSARVIAIDLPGHGESQILQH--HKNS 1483
255546995 1370 VSTYDFSVNS-KGFACSIKVQEVGQKNDDNVVLFLHGFLGTGEDWVPIMKAISGSARCISIDLPGHGGSKISNCgAKESN 1448
297838661 1406 VQRYELRVDV-DGFSHFIRVHDVGQNAEGSVALFLHGFLGTGEEWIPIMKGISGSARCISVDIPGHGRSRVQSH-ASETQ 1483
225425019 1421 LEPNLSIEVVADVLYKLIHSITPGKVTLVGYSMGARIALYMALTssFSDKIKGAVIISGSPGLKNDEARKIRMVKDDSRS 1500
145337303 1482 TSPTFSMEMIAEALYKLIEQITPGKVTIVGYSMGARIALYMALR--FSNKIEGAVVVSGSPGLKDPVARKIRSATDDSKA 1559
242062128 1484 EQFVLTVQLVADLLLKLMCHITDGKVVVVGYSMGARIALHMALN--QDHKIRGAVTISGSPGLRDEASRRRRIAIDKSRA 1561
255546995 1449 KESALSVELVADLLYKLIQHLTPGKISLVGYSMGARIALHMALK--HEDKISRAVILSGSPGLKDEMSRKFRLAKDVSRS 1526
297838661 1484 TAPTFSMEMIAKALYKLIEQITPGKVTIVGYSMGARIALYMALR--FSNKIEGAVVVSGSPGLKDPVARKVRSATDDSKA 1561
225425019 1501 HALITHGLQIFLESWYSGELWKSLRGHPQFNQIVASRLQHKDVRSLAKTLSDLSIGRQRPLWEDLRQCSTPLLLIVGEKD 1580
145337303 1560 RMMVDNGLYIFIENWYNGGLWKSLRNHPHFSKIAASRLLHGDVPSVAKLLSDLSSGRQPSLWEELEDCDTNISLVFGEKD 1639
242062128 1562 QFLMSCGLECFLQTWYSGKLWSSLREHPEFNSLVRTRSKHKNIKALAKVLADSSVGRQKSLWEDLKHLKRPLLIVAGEKD 1641
255546995 1527 RLLIVHGLQLFLDAWYAGELWNSLRSHPRFQEIVSSRLSHDDVYSLAEALSGLSIGRQIPLWEDLKQCNIPLLIIVGEKD 1606
297838661 1562 RMMVDNGLEIFLENWYNGGLWKSLRNHPHFSKIAASRLLHDDVPSVAKLLSDLSSGRQPSLWEELEDCDTNISLVFGEKD 1641
225425019 1581 GKFKRIAQEMCYEIGHGTSNGDDsr--keIYEIVEVPNCGHAAHLENPLPIIRALRRFLTGLENSSTPNERAVPFHGS 1656
145337303 1640 VKYKQIATRMYREMSKSKKSVNN------IIEIVEIPEAGHAVHLESPLRVILALRKFLTRVHNSSTETELSQKLLLA 1711
242062128 1642 AKFKDISQKMRMEIMNQAECGSDgpkgkeLCEMTIIPDSGHAVHVENPLPLVRAVRKFLLKLY--------------- 1704
255546995 1607 EKFKEIAQKMSHEIGQSGEGRGGmg--nnIVQIVEVPNCGHAVHIENPLSVIRALRQFLTRPRKCSTPGHSEEML--- 1679
297838661 1642 VKFKQIATRMYREMSKSKKSVNN------IIEMVEIPEAGHAVHLESPLRMILALRKFLTRVH-KSSQRQLSQKLLLA 1712
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