1SGO


Conserved Protein Domain Family
GSKIP_dom

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pfam05303: GSKIP_dom 
GSKIP domain
This domain is found in GSK3-beta interaction protein (GSKIP), which binds to GSK3beta. It is also found as a short domain towards the N terminus in clustered mitochondria protein, also known as clueless in Drosophila, which is involved in proper cytoplasmic distribution of mitochondria.
Statistics
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PSSM-Id: 398795
Aligned: 25 rows
Threshold Bit Score: 105.742
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1SGO_A        33 MRLEAEAVVNDVLFAVNNM-FV--SKSLRCADDVAYINVETKERNRYCLELTE-AGLKVVGYAFDQVd------dHLQTP 102
CBK19364      22 LELEAIAAVHELAHEVQDI-SV--SEMLPRTSDLIFVNVKTQEGSPYTLELTM-KGWRIASSHTDCMngdy-tkiSLHTK 96 
2_pfamImport   1 LEEEALAAVREHAFAVQSI-GC--SEMLPRTPELLFINLITLENHTNCIELTK-KGWRVASNRNDCMngdf-rqlDIHTK 75 
EGT48135      80 LEDEANNAVREHAYAVKTI-AV--SEMLPRTPQLLFINVTTTENHTHCIELTA-KGWRVASNRNDCMngdf-rqlQIHTK 154
Q22757        42 LEEEAMAAVRENAFAVNLI-GV--SEMLPRTSQLLFINVTTFENHTHCIELTQ-KGWRVASNRNDCMngdf-rqlDIHTK 116 Caenorhabditis ...
XP_003289587   4 FRDEINDAINDVEYGVNKVeHIe-GHTQSEENRAAILRVETYDNIELLVKMCIdTGYSVLEYKNNSDps----lkEDLNK 78 
Q54C74         4 FKEEIDDAINDIEYGVEKVeLVl-DHPISEINHVAVIKTNTKDNLELLIKMSLvDGYSIIEYINKTKdtql-eegLDFQK 81  Dictyostelium d...
XP_004350771   5 FKKEIEAAIEDVSYGVKELkVLdkDPRSDVDGGVVLFNIECHEPLSILIRMSMhEGFSLIELKGELDqes--sakQDQSR 82 
Q9V8F3        13 ALREAQRMVDSCQDFADHL-IV--AEFLPHCRGVAYINIRTLEQVIYCVQLSR-AGYRIVSYEFDDVad----evANCDT 84  fruit fly
EDO33748       8 FRDEAQGVIKDIAFSVSQI-SV--SEKLPSSRESVFLNIETKENICFCVQLCI-QGFRVVSNTFDFCsfdekdsiTQNTP 83 
1SGO_A       103 Y-------HETVYSLLDTLSPAYREA--FGNALLQRLEAL 133
CBK19364      97 Y-------YRNARELLKFISPDHATR--FNECVAQKLSKL 127
2_pfamImport  76 Y-------FDTLHSLLNEISPLYIKK--FGEKLVEKLSEL 106
EGT48135     155 Y-------FDSLHSLLQEISPSFRKK--FFGSIVDKLEDV 185
Q22757       117 Y-------FESLHTLLMDISPLFRET--FGSKLISKLSEL 147 Caenorhabditis elegans
XP_003289587  79 Y-------FDSLSNLLMNYSPEFQKR--FGLKLTERLMGL 109
Q54C74        82 S-------FDSLPNLLMYYSPEFQKQ--FGLKLFERLSNI 112 Dictyostelium discoideum AX4
XP_004350771  83 SspctppvFDSLPNIVMYYSHSFQQK--FNELLFSKLAGL 120
Q9V8F3        85 V-------YESAHQLLAGISPLYGEKygFGREPLGKRKEK 117 fruit fly
EDO33748      84 F-------YETIYALLDTISPGYSQM--FGNELSRKLSEL 114
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