3MVA


Conserved Protein Domain Family
mTERF

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pfam02536: mTERF 
mTERF
This family contains one sequence of known function Human mitochondrial transcription termination factor (mTERF) the rest of the family consists of hypothetical proteins none of which have any functional information. mTERF is a multizipper protein possessing three putative leucine zippers one of which is bipartite. The protein binds DNA as a monomer. The leucine zippers are not implicated in a dimerization role as in other leucine zippers.
Statistics
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PSSM-Id: 460581
Aligned: 36 rows
Threshold Bit Score: 232.492
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3MVA_O        23 LKNLLTMGV---DIDMARKRQPGVFHRMITNEQDLKM-FLLSKGASKEVIASIISRYPRAIT-RTPENLSKRWDLWRKIv 97 
EFJ23121     115 INYLEALGFsaaDLTKLLRKYPMVLHSSVTVDIQPVViYLMGLGVPRSMVPRPLVKYPDMLGfRLEGTMSTSIAYLVSI- 193
XP_009392752 283 VGFLELLGVpeaGIATILLSFPPIIFCDIEKEIKPKLcAFSK-GFEEKDIAKMLMKYPWILStSIQENYEKILAFFNEK- 360
XP_002267835 267 MKFLEDIGVqrgSMRNVLLLYPPIIFYDIEKDIKPRLlAFEKIGAADKDLGRMLVKYPWIIStSIQENYEEILSFFYRE- 345
EEF48706     263 VEFFESLGVpkeRMDSIFLLFPPVILYDI-KVIKRKVlALEKVGAVDEDFGKMIFKYPWILStSIQDNYKEILSFCDAE- 340
XP_002310354 272 VEFLESIGVpkeHMREIFLLFPPVIICDI-TGINRKVqALKKVWAFDKDFGKMLLKYPWILStAIQKNYKEIVSFFHME- 349
Q0WRV2       268 VEFLESIGIpkyCLGKVLLLYPPIMLGKTEEIKRRVAtAMEKVSVVNKDSGKLLLKYPWILSpSIQENYSHIGSFFYSE- 346 thale cress
XP_006342847 279 MVFLDDIGVvegCKRQILLLFPPIIFYDIEKDVRPRLqAILKDGLEAKDFGQMLLKYPWILSrSILQNYENILIFFDDE- 357
ERN12533     270 IEFLKLIGVsegSIRSVFLSFPPIILYDIEREMKPRMrNLEKLGFDNKDIGKMIRKYPWILSsSIQANYSKILAFFSTE- 348
XP_006661537 189 IDFLQYIGIpkaRIASVLLSFPPVILSDVENDIKPRInAWEKVGIEQEYIGRMLLKYPWILStCVIENYGQILLFFHRR- 267
3MVA_O        98 TSDLEIVNILErSPESFFRSNNNLNLENnIKFLYSVGLTRKCLCRLLTNAPRtfSNSLDLNkQM--------VEFLQAAG 169
EFJ23121     194 GVHIRAIAGIVlEFPEILGMRVGNNIKPkVDFLCGLGMPREAAGKILEHHIQ--ILAHDLS-RMkd-----nAALLERAG 265
XP_009392752 361 KVPKSSVDLAIrSWPHILGCSATK-MKSmVEQFNEFGVKKKMLVPVITSSPQ--LL------LKkpkefqevVSFMEEIG 431
XP_002267835 346 KVPKSSVDSGIkSWPHLLGCSTSK-LKLiVEQFGELDVRNKKLGQIIATSPQ--LL------LQkpneflevVSFLEELG 416
EEF48706     341 KVAKASIDKAIrSWPHLLGCSTSK-LKViVDHFGILGVKHKKVGHVIAKSPQ--LL------LRkpeeflqvVSFLKELG 411
XP_002310354 350 KVDKSSVDTAIrSWPHILGCSTSK-LEVmVEQLAELGIRNKKLGQVISKSPQ--LL------LRkpqeflqvVLFLEDLG 420
Q0WRV2       347 SVLKMDIDHAIrRWPLLLGCSASN-MEMmVKEFDKLGVRDKRMGKVIPKMPQ--LL------LCkpqeflkvVCFLEDLG 417 thale cress
XP_006342847 358 KVPKISVAQAIkSCPLLLGLSVNK-LKLvVEQLRDFGIRNQKLGKVIATSPQ--LL------LQkpqefsqvVCFLRDLG 428
ERN12533     349 KVPKLYVDGAIkSWPHILGCSINR-MKLlVEQFGEMGVTNDNLGRVIASCPQ--LL------LQkpqnfvmvVSFLEELG 419
XP_006661537 268 KISSTVLSVAVrSWPHILGCSTKR-MNSiVELFDDLGISKKMLVPVVTSSPQ--LL------LRkpnefmqvVLFFKDMG 338
3MVA_O       170 LSlghndpADFVRKIIFKNPFILIQS-TKRVKANIEFLRsTFNLNsEELLVLICGPGAEILDLS-NdyarRSYANIKEKL 247
EFJ23121     266 VS------GDGLPGLVLQMPTVLVDPiDKLVESLADWLEkTLKVP-RASTGRVLEKLPQVLYLH-R----RFAAARVSFF 333
XP_009392752 432 FD------SKTIGRILCRCPEIFASSvDNTLRKKVNFLA-DFGVS-RDCLLRVVRKYPEMLLLDtD----NTLLPRMIFL 499
XP_002267835 417 FD------RETVGRILGRCPEIFAANiEKTLKKKLEFLA-SIGIF-KDHLPRVIRKYPELFVSDiN----RTLLPRTKYL 484
EEF48706     412 FD------QESVGKILVRCPEIFATSaEKTLRKKVEFLT-WMGVY-GDHLCRTIKKYPELLVSDiE----RTLHPRMKYL 479
XP_002310354 421 FD------RETVGQVASRCPEIFAASiEKTLKKKIEFLD-RIGVS-KDHLPRVIKKYPELLVSDvN----RTILPRMKYL 488
Q0WRV2       418 FQ------KEIVGQILCRCPEIFGCSiEKTLQKKLIFLT-RFGVS-TTHFPRIIKKYPEFLIYDaD----KTVLPRLKYL 485 thale cress
XP_006342847 429 LD------DDIIGRILGRCPEIFASSiGRTLERKLNFLM-GIGVS-RSHLPRIIKKYPEFFVCDiH----RALRPRMTYL 496
ERN12533     420 FN------CESVGKILSRCPEIFAASiEGTLKKKIDFLI-ALGIS-HDHLPRIIRKYPELLVCDiH----KALQPRMKYL 487
XP_006661537 339 LD------KKTVAKILCRSPEIFASSvDNTLKKKINFLI-DLGVS-THHLPRIIKKYPELLLLDmN----RTLLARINYL 406
3MVA_O       248 FSLGCTEEEVQKFVLSYPDVIFLAEK-KFNDKIDCLMEE-NISISQIIENPRVLDSSI-STLKSRIKELVNAGCNLStlN 324
EFJ23121     334 QARGFTTQEIGKMVVLCPQILVLDPR-SMRESMEFYVKQmKRSIKELVEFPAFFTYGLeERIRFRYKRVAEKGLSFS--L 410
XP_009392752 500 MRVGLSKREVCSMICRFSPILGYSIEmVLKPKLDFLLRTmKKPLKEIVEYPRYFSYSLdKKIKPRFWVIHSRKLECS--L 577
XP_002267835 485 RKTGFSKRDIAFMIRRFSPLLGYSVEeVLRPKLEFLVKTmEKPVKEVVDYPRYFSYSLeKKIKPRFWVLKVRNVDCS--L 562
EEF48706     480 MEVGVTKEEVGLMVGRFSPLLGYSIEeVLRPKYEFLVNTmGKGVKEVVEYPRYFSYSLeKKIKPRYWAVMRRNVECS--L 557
XP_002310354 489 KDVGLSKKDIAFMVRRFSPLLGYSIDeVLRPKYEFLVNTmKKPVEDIVGYPRYFSYSLeKKIMPRFWVLKGRNIECS--L 566
Q0WRV2       486 MEIGISEREIAFMIRKFSPILGYSIDkVLRPKFEFLVNSmEKPVREVIEYPRYFSYSLeKRIKPRFRVLKGRNIECT--L 563 thale cress
XP_006342847 497 MHVGLSKREVALMVCRFSPLLGYSIDeVLKPKVEFLMNSmGKPISDVVEYPRYFSYSLeKKIKPRFWVLKGRNMECS--L 574
ERN12533     488 MKVGLTKREVASMIHRFSPLLGYSIEkVLRPKLEFLVYTmHKPVRDVVDYPRYFSYSLeKKIKPRFWVLKGRNVQCS--L 565
XP_006661537 407 LDMGLSKKNVCSMIYRFSPLLGYSTElIMKPKLEFLLRTmKKPLKAIVEYPRYFSYSLeGKIKPRFYVLQSRNIDCS--L 484
3MVA_O       325 ITLLSWSKKRYE 336
EFJ23121     411 AWFLNCSNAVFQ 422
XP_009392752 578 KDMLSKNDDEFA 589
XP_002267835 563 KDMLAKNDEEFA 574
EEF48706     558 KEMLDKNDDDFA 569
XP_002310354 567 KDMLAKNDEEFA 578
Q0WRV2       564 QEMLGKNDEEFA 575 thale cress
XP_006342847 575 KSMLGKNDEEFA 586
ERN12533     566 KEMLGKNDEDFA 577
XP_006661537 485 TDMLAKNDEHFA 496
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