Conserved Protein Domain Family
COG5493

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COG5493: COG5493 
Uncharacterized protein, contains PD-(D/E)XK nuclease domain [General function prediction only]
Statistics
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PSSM-Id: 444244
Aligned: 39 rows
Threshold Bit Score: 162.074
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_100921689   1 MNAe------tLKEAIRRELPALLREDPDLRGYIQDLMrgqfadrlETQDRFEKLL---GELRrdREANERKw------- 64 
ADM27399       1 MALe------lLTEEERQRILKTLEKDTEFRLAIAGLL------------GLREIL---EELRk-LREDFNRfv------ 52 
ADM27402      65 LSEri----------------agLEERQQ-----------------KLEEGFQKIL---ERIAi-LEERYQKl------- 100
WP_012308926   1 MAL---------SAEEKRRFLRSLDEDIEFRYAVAGYL------------GISEIL---KRLDs-LEESMLKl------- 48 
WP_013335521  41 svvsdltrtvqrlvegqerlweennklwqevrrlaegqealrtdvsKLWEENNKIW---QEIKa-LRENQEKl------- 109
WP_013336285   1 MSS-----------DLRKELLKLLKEDEEFRYAVMGLL------------GISDLK---SSVDn-LVKAITDlkd----- 48 
WP_052883143   1 MSLdwgkleevVERAVRRARSEELREVADAVRTLAEYM----------KTGFQETNkriEELAk-RLETHGR-------- 61 
WP_020963230   1 MNL-------------RGEFLRLLDEDREFRLMVAGKL------------GYGDVL---RRLEr-HDRKFNKv------- 44 
WP_052885698   1 ------------------------------------------------------ML---EQHSe-ILEQHSK-------- 14 
WP_103287301   1 MHS--------SKEELKKVLLNLLLEDVEFRHAVAGAI------------GYKEIL---DRIAk-VDEDMNKrflemeek 56 
WP_100921689  65 --------DANErkweaqeqkwdaqeqkwdaqeqKWDaqeqrweaqeqrweAQERKWDAQeqkwekqqtilRDFMDEQSR 136
ADM27399      53 --------------------------------------------------vEQEKRWEEN-----------NRRWEEVYK 71 
ADM27402     101 --------EERFa---------------------KLE--------------ERFVELEER-----------VIKLEERVA 126
WP_012308926  49 -------wENQNkl------------------------------------wEEVKSLREG-------------------- 65 
WP_013335521 110 -------wENQNkl------------------------------------wQEVKALREEq----------ERRWQENER 136
WP_013336285  49 -------------------------------ivaKQG--------------EEISELRKA-----------VEVLVKSHD 72 
WP_052883143  62 ----------------------------------LLE--------------EHGKRLEEL-----------VRAVAELGK 82 
WP_020963230  45 --------------------------------------------------vNEIKKFREDf----------NTEMSKLRG 64 
WP_052885698  15 ----------------------------------ILE--------------EQRKLLEEH-----------RKVLEEHTK 35 
WP_103287301  57 mnkrflemEEKMnkrfleme------ervnarflKVE--------------EDIKELRKDln-------dlRRDMQEGFK 109
WP_100921689 137 LWKENAAererRWAQNT-------RQFDEVHEAIMAQAKKHERGIGALGSRWGTQSEATFRNALASILEQ-SFG-VTVMR 207
ADM27399      72 RFEHIETt---------------lAIHTKNLEQLTKAIGELKSFVGSIGRRWGRDLEKMILELYRDIVKGfGIDiERIEK 136
ADM27402     127 RVEEELV----SVKKAL-------EEHSRVLAFHSKKIEEMSRAFAIISYRWGLGSESVFRDSMKEILEK-ILGvSKVDR 194
WP_012308926  66 --------------------------QDKLREEFDKLSMRVEVTIGSMGRRWGEDLERMVLEIFKEALEKrGIEpGKVEK 119
WP_013335521 137 RWEENNR----RWEEAYkrfevieTELRNLREDFNKSMAAINRRLDALGARWGVISEEAFREGMKGVIER-ILGtAKVEK 211
WP_013336285  73 ELKKVVE----ALSEDV-------RRHGEVIIVMQTSIEKLTSSVTALGYRYGLFIEEAFRESIKYLVSD-LLKvYEVRR 140
WP_052883143  83 RVEEQGRi---------------lAEHGRRLDELTKAVAELKVAMGSLGRRWGRDLERTVLEIYRDALEGkGVEpGRVEK 147
WP_020963230  65 DFN---------------------AEMKKLREDFNKLSMRVEVTIGSMGRGWGEDLERMVLEIFREELEKrGIEpGKVEK 123
WP_052885698  36 ILQQHSKm---------------lEEHSRQIQEQGKSLAELKVVIGSMGRRWGSDLERTVLEIYRQALETkGIKpENVAK 100
WP_103287301 110 RHDEEFAkvwkSIEDLR-------RDMQEGFKRHDRLIQELSISIGSLGRRTGKDMERLILNIYRDQLMQlGIDkDKARR 182
WP_100921689 208 VDEYDDAGTVFG-RPDQVELDIIIKNGLLLICELKSSIDKAGMYIFERKARYYEQRHGQ---TAnRLIVISPMIDPRAQQ 283
ADM27399     137 VYFRDYDGKYLQ-RGARIELDIYMSNSIVYLIEVKSLVEEEDIEWFNKKCEIFAKEKNI---SNyKKLVIAINITKEALE 212
ADM27402     195 WIYYDAEGFVFG-RPTVIEADIVVRDNVHMLIELKSSASEGDVLKLLRVGELYSRVTGV---RP-KLVLVAIAMRKKDIE 269
WP_012308926 120 LRFVDRDGSITGiKGKVVDIDISVKDDKLYLIEVKSRAELDHIDALYMKARAAEKYLNR---SAdKIILVSVNVDREAYD 196
WP_013335521 212 WTYNDTNGEVYG-HPAIVDVDLVIRDNVHVLVEVKSSISRGDVAEFWRVGRLYERVNGV---KP-RLVMISPYVDDKAME 286
WP_013336285 141 WTYYDSDGFVFG-HPSIIDVDVLTRDNEHILVVYRVSIDRGDVAELFREGVLYERINKV---KP-RLLIVGPVIRRRALE 215
WP_052883143 148 FVYTDVDGRYLK-PGASIEVDVYIHDGKMYLLEVKSHAELEDVEWFAEKAGAVEKILGR---KAhRLIIVAVNIDKEALE 223
WP_020963230 124 LRFTDRDGSITGvRGRIVDIDVSVRDGKLYLVEVKSRAELDHVEALYEKVRAVEKYLAK---SVsGVFLVAVNVDKEAYD 200
WP_052885698 101 FTYEDVEGKYYR-RGAKIEVDIYMHNDTTILIEVKSRAELEDVEWFLDKAGIVEKIIGR---KAdKLIIVAVNIDKDAYE 176
WP_103287301 183 FEYIDKEGLY-GlKGKRYEFDIIVSNSHADILEIKNRVAEDDVVTFYEKVNSIKPVIEReygSIkRLVTVSIHIDREALT 261
WP_100921689 284 VADQLGIETFSDSLD 298
ADM27399     213 RAKELGIETIYGSVI 227
ADM27402     270 LAREMGIEVYAGPEL 284
WP_012308926 197 RAEELGIEVICGHVI 211
WP_013335521 287 LARELGIEVYTNVT- 300
WP_013336285 216 LARELGVEVRASEVV 230
WP_052883143 224 RAAQLGIDAVYGAVI 238
WP_020963230 201 RARQLGIEVICGSII 215
WP_052885698 177 RAQALGIDVVAGAVI 191
WP_103287301 262 KAKELGIECIYGYMV 276
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