Conserved Protein Domain Family
DUF4515
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pfam14988: DUF4515 
Domain of unknown function (DUF4515)
This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.
Links
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Statistics
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PSSM-Id: 405647
Aligned: 8 rows
Threshold Bit Score: 146.837
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_997163     77 ENQLFMEYLRKNKEQCEKKQEELWKQYVQECGEIERERQELASRYNQRNAALQAQLLQGRKTQKDLKQQLQALKPVYKIK 156
NP_001170975 194 ENKAFLEFLMKKNQKTQEKYDSLWKDYIQQYQEIEDRRREMVSTFTSRTGSLQKQLKENKKLEASLKKKLKALAPIANIK 273
NP_001034317 199 DSKLFLEYLQQKKEEKQRKYDSLWKDYIQQCEEIEDRRRELVSTFTSRTAGLQKQLEQGRKLEASLRKKMKALEPVAQVK 278
Q9D496       202 EKNCFLRVLRKQSEQCKKKHGQLWNQYVQDLGEIIRRKQELTLRFAKQTEELQTQLFQGKIKQSQLEQQFQSMEHISSIQ 281 house mouse
XP_002595443  87 ESHEYMSYMAKKTHKRQSTIVSLSDQNQKEIEKLQQEKSEVLAEYEQKKAGLRQLLLERENELAKTKKELQELDEFKKLQ 166
Q8ND07        77 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRK 156 human
EFB20524      35 ENKFFLEYLANKTEEYGRQTEKLWNNYLQKNEEIERRRQKSASKYAKQTSEFKRELLQKEKIQFNLKQQLQALRNVSLLK 114
Q6ZUS5        35 ENRFFLEYLTNKTEEYTEQPEKVWNSYLQKSGEIERRRQESASRYAEQISVLKTALLQKENIQSSLKRKLQAMRDIAILK 114 human

NP_997163    157 EGQDVKIQTLEKEQEKVRSETATKDREAHFQFLREKALMEKELQEWHLMELGQINTTGLTRKYKALALAAKQAHSEFCGS 236
NP_001170975 274 ESQDWEIETLELEKASIVADIPFLDREAHLQFLKERAALAKQVEDLNLLESGEDITRELKKKTKAWDTAAKQAYEDFCHN 353
NP_001034317 279 EHQEQTIQALELEKASIGTDLSLLDREAHLQFLKERAALEKQLEDLNLLESGEQITRKLKKKAKALDAMAKQAHKGFWEG 358
Q9D496       282 KSQEMKIQMLEKELEDVKAETARKDHQAHLQFLQRKTHLMRQIQELRSLQAGDHNTPEVRQKAQLFKSTAKKVNSEYCRS 361 house mouse
XP_002595443 167 ADQISRIKDLEREVLKMRGVHSDTLQQLKAQFLKEKSDYQHES-DQRITSMGKLANKE-----------AARCLDEHTQM 234
Q8ND07       157 IQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEA-EKKIIMLAERAHHE-----------AIVQLNDAGRN 224 human
EFB20524     115 EKQEREIQILQEEKKKTQAETDVKKQEVKVQLLQEKAFLEKQLSEPDMRQLGKRKRKELDRKAQALELEAKQYTFEFYRS 194
Q6ZUS5       115 EKQEKEIQTLQEETKKVQAETASKTREVQAQLLQEKRLLEKQLSEPDRRLLGKRKRRELNMKAQALKLAAKRFIFEYSCG 194 human

NP_997163    237 LHRENQQLRKELQQLSQEYGRLDAVRSQLEKHRQLAKEQQWYLEAL 282
NP_001170975 354 INARNRQLRTELQQLDWEFCNLEDRREKLERRKQRWKEQQWYLEAL 399
NP_001034317 359 IKAQNRELKTQLWQLNQEFCKLEAGKEKLERRKQRWKEQQWYLEAL 404
Q9D496       362 VCRENQELQEDLLKLIQEYYKLESIKRKLEMCKERLKEEQCYQEAL 407 house mouse
XP_002595443 235 IKLENRQLRHELLNLIKETRALHEHKLRLEDQRKELLREQQYAKDL 280
Q8ND07       225 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLL 270 human
EFB20524     195 VRRENRELQKKLLQQTQQCQELQAIKSQLKNQKQQLQQEQWYVQCL 240
Q6ZUS5       195 INRENQQFKKELLQLIEQAQKLTATQSHLENRKQQLQQEQWYLESL 240 human
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