Conserved Protein Domain Family
bass

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TIGR00841: bass 
bile acid transporter
The Bile Acid:Na+ Symporter (BASS) Family (TC 2.A.28) Functionally characterized members of the BASS family catalyze Na+:bile acid symport. These systems have been identified in intestinal, liver and kidney tissues of animals. These symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts. Functionally uncharacterised homologues are found in plants, yeast, archaea and bacteria. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Statistics
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PSSM-Id: 188087
Aligned: 12 rows
Threshold Bit Score: 308.11
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAA18004         1 MESNFLTTIFLPLaLFLIMFGMGLGLTIKDFNRIWLEPKAVAIGLIAQLVMLPMVGFGLSSLFSLSPELAVGLMILAACP 80  Synechocystis...
P26435          22 ATDKALSIILVLM-LLLIMLSLGCTMEFSKIKAHLWKPKGVIVALVAQFGIMPLAAFLLGKIFHLSNIEALAILICGCSP 100 Norway rat
O08705          22 ATDTALSVILVVM-LLLIMLSLGCTMEFSKIKAHFWKPKGVIIAIVAQYGIMPLSAFLLGKVFHLTSIEALAILICGCSP 100 house mouse
Q14973          22 PTDLALSVILVFM-LFFIMLSLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSP 100 human
Q28727          30 ILSVVLSTVLTIL-LALVMFSMGCNVEIKKFLGHIRRPWGIFIGFLCQFGIMPLTGFVLAVAFGIMPIQAVVVLIMGCCP 108 rabbit
Q12908          29 ILSVVLSTVLTIL-LALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCP 107 human
Q62633          29 ILSTVMSTVLTIL-LAMVMFSMGCNVEINKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCP 107 Norway rat
Q60414          29 ILSVVMSTVLTIL-LALVMFSMGCNVELHKFLGHLRRPWGIVVGFLCQFGIMPLTGFVLSVAFGILPVQAVVVLIQGCCP 107 Chinese hamster
P09131         186 HFSENPILYLLLPlIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSP 265 human
AAB84443        31 SLFTWISSYITIF-LGIIMFGMGLTLQADDFKELVRKPWQVIIGVIAQYTIMPLVAFGLAFGLHLPAEIAVGVILVGCCP 109 Bacillus subt...
AAC07854        22 EFFANLKPLILPL-LIVIMLSMGLTLTPEDFKEIARKPFIVFYGALLQYTVMPLSGYLLSKLFKLPPELLVGVVLVGSAP 100 Aquifex aeoli...
TIGR:At2g26900  60 LWVTWLETDLFTLgLGFLMLSMGLTLTFEDFRRCLRNPWTVGVGFLAQYMIKPILGFLIAMTLKLSAPLATGLILVSCCP 139 thale cress
BAA18004        81 GGSTSNVITYLLKGNVALSITLTAISSLVTIITIPLVVNLAANYFMG-EQFAlqLPFLKTVLQiAVITIIPVSLGMIFYH 159 Synechocystis...
P26435         101 GGNLSNLFTLAMKGDMNLSIVMTTCSSFSALGMMPLLLYVYSKGIYD-GDLKdkVPYKGIMIS-LVIVLIPCTIGIVLKS 178 Norway rat
O08705         101 GGNLSNLFTLAMKGDMNLSIVMTTCSSFTALGMMPLLLYIYSKGIYD-GDLKdkVPYKGIMLS-LVMVLIPCAIGIFLKS 178 house mouse
Q14973         101 GGNLSNVFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIYSRGIYD-GDLKdkVPYKGIVIS-LVLVLIPCTIGIVLKS 178 human
Q28727         109 GGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLYVYTKMWVDsGTIV--IPYDNIGTS-LVALVVPVSIGMFVNH 185 rabbit
Q12908         108 GGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDsGSIV--IPYDNIGTS-LVSLVVPVSIGMFVNH 184 human
Q62633         108 GGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDsGTIV--IPYDSIGIS-LVALVIPVSIGMFVNH 184 Norway rat
Q60414         108 GGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDsGTIV--IPYDSIGTS-LVALVIPVSIGMYVNH 184 Chinese hamster
P09131         266 GGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLLSIhETLH--VPISKILGT-LLFIAIPIAVGVLIKS 342 human
AAB84443       110 GGTASNVMTFLAKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLP---VS--PGSLFISI--LQAVLFPIIAGLIVKM 182 Bacillus subt...
AAC07854       101 GGTASNLITYLSRGDLSYSISMTTTSTLLSPLFTPLWTYVLAGKYVE-------VPFLSMFETtLKIVIVPVLLGMVLRY 173 Aquifex aeoli...
TIGR:At2g26900 140 GGQASNVATYISKGNVALSVLMTTCSTIGAIIMTPLLTKLLAGQLVP-------VDAAGLALStFQVVLVPTIIGVLANE 212 thale cress
BAA18004       160 FL-PKIAMVMEKnVKWLSLFFLGIIIVAILVKEREN--LADFFLQVGGVTVTLNLLTMGLGYGIAILAGLGLaERK-SIT 235 Synechocystis...
P26435         179 KR-PHYVPYILK-GGMIITFLLSVAVTALSVINVGNsiMFVMTPHLLATSSLMPFSGFLMGYILSALFQLNP-SCRrTIS 255 Norway rat
O08705         179 KR-PHYVPYVLK-AGMIITFSLSVAVTVLSVINVGNsiMFVMTPHLLATSSLMPFTGFLMGYILSALFRLNP-SCRrTIS 255 house mouse
Q14973         179 KR-PQYMRYVIK-GGMIIILLCSVAVTVLSAINVGKsiMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLNG-RCRrTVS 255 human
Q28727         186 KW-PQKAKIILK-VGSIAGAVLIVLIAVVGGILYQS--AWIIEPKLWIIGTIFPMAGYSLGFFLARIAGQPWyRCR-TVA 260 rabbit
Q12908         185 KW-PQKAKIILK-IGSIAGAILIVLIAVVGGILYQS--AWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWyRCR-TVA 259 human
Q62633         185 KW-PQKAKIILK-IGSIAGAILIVLIAVVGGILYQS--AWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWyRCR-TVA 259 Norway rat
Q60414         185 KW-PQKAKIILK-IGSIAGAILIVLIAVVGGILYQS--AWTIEPKLWIIGTIYPIAGYGLGFFLARIAGQPWyRCR-TVA 259 Chinese hamster
P09131         343 KL-PKFSQLLLQvVKPFSFVLLLGGLFLAYRMGVFI--LAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVaQRR-TVS 418 human
AAB84443       183 FFrKQVAKAVHA-LPLVSVIGIVAIVSAVVSGNREN--LLQSGLLIFSVVILHNGIGYLLGFLCAKLLKMDYpSQK-AIA 258 Bacillus subt...
AAC07854       174 FLrYQINKVEKF-LPFLAVFSISLIIAVIFALNSKL--LKELSFLVLSVVLIHNVLGFLLGYLFGLLAGLDKrKVK-ALS 249 Aquifex aeoli...
TIGR:At2g26900 213 FFpKFTSKIITV-TPLIGVILTTLLCASPIGQVADV--LKTQGAQLILPVALLHAAAFAIGYWISKFSFGES-TSR-TIS 287 thale cress
BAA18004       236 IEVGIQNGTLAIAIATTLLNaPIMAIPAAIYSVVMFLTSGIFAGLLKAKIFRGLKST 292 Synechocystis sp. PCC 6803
P26435         256 METGFQNIQLCSTILNVTFP-PEVIGPLFFFPLLYMIFQLAEGLLIIIIFRCYEKIK 311 Norway rat
O08705         256 METGFQNVQLCSTILNVTFP-PEVIGPLFFFPLLYMIFQLAEGLLFIIIFRCYLKIK 311 house mouse
Q14973         256 METGCQNVQLCSTILNVAFP-PEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEKFK 311 human
Q28727         261 LETGMQNTQLCSTIVQLSFS-PEDLTYVFTFPLIYSIFQIAFAAIFLGIYVAYRKCH 316 rabbit
Q12908         260 FETGMQNTQLCSTIVQLSFT-PEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCH 315 human
Q62633         260 LETGMQNTQLCSTIVQLSFS-PEDLNLVFTFPLIYTVFQLVFAAIILGMYVTYKKCH 315 Norway rat
Q60414         260 LETGLQNTQLCSTIVQLSFS-PEDLNLVFTFPLIYSIFQIAFAAILLGAYVAYKKCH 315 Chinese hamster
P09131         419 IEVGVQNSLLALAMLQLSLR-RLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLF 474 human
AAB84443       259 IEVGMQNSGLGAALATAHFS-PLSAVPSAIFSVWHNLSGSMLATYWSKKVKKKQAGS 314 Bacillus subtilis
AAC07854       250 IEVGMQNSGLSTVLALKYFS-KVSALPSAIFSLSQNLIGVVLSLFFRRL-------- 297 Aquifex aeolicus VF5
TIGR:At2g26900 288 IECGMQSSALGFLLAQKHFTnPLVAVPSAVSVVCMAVS---FHSHFTKVHMQIP--- 338 thale cress
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