Conserved Protein Domain Family
PPP1R35_C

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pfam15503: PPP1R35_C 
Protein phosphatase 1 regulatory subunit 35 C-terminus
This is the C-terminus of protein phosphatase 1 regulatory subunit 35. This protein interacts with and inhibits the serine/threonine-protein phosphatase PPP1CA.
Statistics
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PSSM-Id: 434762
Aligned: 12 rows
Threshold Bit Score: 109.046
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001371934 117 PGLQSTLALGQQLESVREAtalgQFDALKAAGEQLKSSFLSRCEMEENISEGLNVPRSQRLYRDLVSLQVPKEQVLNAA- 195
XP_001626150  83 PCVNSSARISHKLQMLQEC----KFNSAIAIAAELEKSETTKTALLERAALGVNVKRDQNKYSDLVPLDLVAEDLIGVH- 157
XP_002129907 276 sKYHSSLVAGQELQKLQEE----EFDAVTAVKKKLEDDKNLRAHISTQAATGTNIDPDEVLYNNLVSLDVSSGDIAAT-- 349
EKC18934     323 PEYNSTLRMRKEIESIKES----HVDVVKALDKKLQISDTVSSDIREKASTKVNVSSPR--FTGLVSLSVPVEDI----- 391
CDS41214      75 PKINSIRALQEEIIQIASRin-kASQSAASTAEKLATGTRGYR----GGGTCLNFAREERLYKDLLAVSLDDAEVAKAEr 149
XP_001864281  75 PELHTALNVQKQIEKVQGA----KVKAPASIGELTPKS---QKFVRNQITRKLNFQHDDNVFKGLVPVNVNDSVLIP--- 144
XP_023511109 111 PAPHSSLALSFELQAARAAag-gPFDAAKAVEEQLRKSFQTRCGLEESVAEGLNVPRSRRLFRDLVSLQVPEEQVLNAA- 188
XP_004071932 122 aELNTTLALKAELQSLQEA----EFDSEKALHETLQKSERTKNLINARATEVVNISRSQLLFHSLVSVDVQQEQLLSRV- 196
NP_001038856 101 aELNTTLALRAELEEEAEQ----TFDAEKAVREKLQSSTLTKNHVNSKAAEGLNFPRSQQLYRALVSVSLSRDQLISQA- 175
XP_015196013 109 PELNTTLAVGVELRGVAEA----EFDPKRAVQDQLRKSAHRKNAIEIRATEGVNIPRSQQLYRALVSVSVPEDELISEA- 183
EEN46438     180 PEFNTTLALGKELQKLKFG----EFDAKAAALEKLKTSEQVQEKVSEKSAEGVNIAPAEQKYRDLVSLDVPVQRVLEAA- 254
EFX90209     120 PIFQSSVVLMKNLETLKNL----EIETRNLLSHKVEKDKKMQKLLNSKVSTVLN--PSRQIFSRLQPISFNVEQLVDQDe 193
XP_001371934 196 ---LMERLALLPPQPQVPPhke---vpaAGPELSILCDp---QSLAHESPHlilegfpllklRPQPHPAE---------- 256
XP_001626150 158 ---TQQRASFKPREPKVPD---------NEPQIMDFFS----EEFEEETSR-----------CVFPGPEEvdnevddddd 210
XP_002129907 350 ---TQFRRIKRPSFTKLGPs--------EEIQIMDLFPp----DLIQEKVIveskcyslptlSTVTTPLD---------- 404
EKC18934     392 ---------DKPQTFRAKPvkarsqsktQEPDLMEFFS----TEFQRETPElstpglstpsePLVTASPM---------- 448
CDS41214     150 dktARRRRRLLAEAARLHPpka---eilPEPCPMKFFNp---QLHIFQSARlditgmtdyrpLPESLSTA---------- 213
XP_001864281 145 ---ARKRPLRSKFVAKEKRd--------PEPELADFLRpiakCSIEFEPYL-----------PPEPAPRR---------- 192
XP_023511109 189 ---LREKLALLPPQGRAPApkd---ppgPGPDMTILCDp---ETLFYESPHltldglpplrlQLRPRPSE---------- 249
XP_004071932 197 ---LKERLHLPPTASCPPTpt------aEGPTLLFFKT----SSLVHQKPLpqeeglldskaLPSPCPPR---------- 253
NP_001038856 176 ---LQDRPALAPPTASQNNkfss--pppEGPDILQFYSp---DKMLRETPLlpgdhiplprpRPVPRPAH---------- 237
XP_015196013 184 ---VKERLLLAPPPRAHGNkes----ptAGPDLLHFYSp---SELLRETPFlpgegvtlprpRPVPRPSQ---------- 243
EEN46438     255 ---VEEKLSMVKDVRHERPqv------qEEPDIMDFFT----DDLMFESADystthipsvtaSLQIAPPH---------- 311
EFX90209     194 trlHNLAEKNAPQMRYRD----------PEIALKDFID----CMVISKTPIlpessfhdqccQFQINPFI---------- 249
XP_001371934 257 -----DTFLMHQTL 265
XP_001626150 211 gggggHAFDLYRHV 224
XP_002129907 405 -----SVMSLYEHS 413
EKC18934     449 -----SAFDLYRHN 457
CDS41214     214 -----HQLDairld 222
XP_001864281 193 -----PNFDNFAHI 201
XP_023511109 250 -----DTFLMHRTL 258
XP_004071932 254 -----FAFDLYRRQ 262
NP_001038856 238 -----TTFHLHRLh 246
XP_015196013 244 -----ATFDLYHKH 252
EEN46438     312 -----MTFDLYRHM 320
EFX90209     250 -----------QHQ 252
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