Conserved Protein Domain Family
PRK05434

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PRK05434: PRK05434 
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Statistics
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PSSM-Id: 235463
Aligned: 577 rows
Threshold Bit Score: 566.267
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
159897411   1 MTTPRPVLLAIMDGWGLAPA--GPGNGVSLANTPNVNHWMATCPTTQLHASGLDVGLP-EGQIGNSEVGHLNIGAGLVVY 77 
294827652   8 TFRSRKVLLIILDGVGYSPKgpESGNAIAGAKLPFLNRVWNQFPTLHIQAHGKAVGMPsDDDMGNSEVGHNVLGSGRIFD 87 
45656283   12 TFRSRKVLLIILDGVGYSPKgpESGNAIAGAKLPFLNRVWNQFPTLHIQAHGKAVGMPsDDDMGNSEVGHNVLGSGRIFD 91 
189910040  10 GPLTKQVLLIVLDGVGYTEQgyQNGNAVAKANMPVLKGLWENHPTVLLKAHGTAVGMPsDEDMGNSEVGHNVLGSGRIFD 89 
183219916  10 GPLTKQVLLIVLDGVGYTEQgyQNGNAVAKANMPVLKGLWENHPTVLLKAHGTAVGMPsDEDMGNSEVGHNVLGSGRIFD 89 
116327026   8 TFRSRKVLLVILDGVGYSPKgpEFGNAIAGAKLPFLNQVWNQFPTLHIQAHGKFVGMPsDEDMGNSEVGHNVLGSGRIFD 87 
116332315   8 TFRSRKVLLVILDGVGYSPKgpEFGNAIAGAKLPFLNQVWNQFPTLHIQAHGKFVGMPsDEDMGNSEVGHNVLGSGRIFD 87 
21225111    6 PVLAGPGILLVLDGWGSADA--ADDNALSLARTPVLDELVAQHPSTLAEASGEAVGLL-PGTVGNSEIGHMVIGAGRPLP 82 
154251927  22 MTGVRPLVLVLLDGWGVRTE--REGNALATARTRIYDRLAAASPQSLLRASGEAVGLP-SGKPGYAQAGYAALGAGRPIE 98 
187251745   1 --MKKKVMLVVRDGWGKREE--VKYNAVRQAKTPNITSYLENYPSTFLEAAGVMVGLP-AGYMGSSEVGHLNMGAGRIVV 75 
159897411  78 QDSTRISESIK---SGEFFENPAFLEAVQIVKERGTNMHLIGLIGRGGVHAYDIHLAGLLQLMAQQGVNHTYIHAFMDGR 154
294827652  88 QGAKLVSNSIA---SGDIFNGQAWKEVIGNSKKNNSTLHLLGLFSDGNVHSHIDHTKALISQAILEKVPKIRLHILLDGR 164
45656283   92 QGAKLVSNSIA---SGDIFNGQAWKEVIGNSKKNNSTLHLLGLFSDGNVHSHIDHTKALISQAILEKVPKIRLHILLDGR 168
189910040  90 QGAKLVSQSIE---NGSLFQGPIWKKMVSNCIQNESNFHFLGLFSDGNVHSHIHHLKALIDQAIKENIKKIRLHILLDGR 166
183219916  90 QGAKLVSQSIE---NGSLFQGPIWKKMVSNCIQNESNFHFLGLFSDGNVHSHIHHLKALIDQAIKENIKKIRLHILLDGR 166
116327026  88 QGAKLVSNSIA---SGDIFQGQAWKEVIDNTKKNKSTLHLLGLFSDGNVHAHIDHTKALISRAISEKVTKIRLHILLDGR 164
116332315  88 QGAKLVSNSIA---SGDIFQGQAWKEVIDNTKKNKSTLHLLGLFSDGNVHAHIDHTKALISRAISEKVTKIRLHILLDGR 164
21225111   83 YDSLLVQQAID---SGALRSHPRLDAVLNEVAATSGALHLIGLCSDGQIHAHVEHLSELLAAAATHQVERVFIHAITDGR 159
154251927  99 PPAARITPAFQhdgSADIAAHPVLRDLISRVRPLGGAVHLIGTMTPSGISGHQRYLAVLAALLSHEGV-KVWVHAVMDGQ 177
187251745  76 QELKRLKDTIE---DGSLFNAKPFKACIDNAAQNNSALHLMGLVQDEGVHAHQDHLFAIIEHAAKKGVKTIYVHFFADGR 152
159897411 155 DTLPQSGLGYMRELQQTISQI-----------GVGQVASVIGRYYAMDRDKRWERVGAAYAAMVEGVG-H-T-A-SDPIS 219
294827652 165 DVPEKSALDYLNPFETWLDSLrksgtdiriasGGGRMTITMDRYEAD-----WSMVERGWKVHVKGEGrYfSsA-KEAIE 238
45656283  169 DVPEKSALDYLNPFETWLNSLrksgtdiriasGGGRMTITMDRYEAD-----WSMVERGWKVHVKGEG-RyFsSaKEAIE 242
189910040 167 DVPEKSALDYLIPFETYLETYrkagidiciasGGGRMELTMDRY-----DADWSMVERGWNHHVEGEGrIfAsA-KEAIE 240
183219916 167 DVPEKSALDYLIPFETYLETYrkagidiciasGGGRMELTMDRY-----DADWSMVERGWNHHVEGEGrIfAsA-KEAIE 240
116327026 165 DVPEKSALDYLNPFETWLDSFrkngidiriasGGGRMTITMDRYEAD-----WSMVERGWTIHVKGEGrKfSsA-KEAIE 238
116332315 165 DVPEKSALDYLNPFETWLDSFrkngidiriasGGGRMTITMDRYEAD-----WSMVERGWTIHVKGEGrKfSsA-KEAIE 238
21225111  160 DVADHTGEAYLTRVAELAAAA-----------GTGQIATVIGRGYAMDKAGDLDLTERAVALVADGRG-------SPADS 221
154251927 178 DTRAQSGIEHLSEFLDDIAGA-----------ENAELGSVMGRSFGFDDLSDPAAIAAAWRALANAEA-PyT---EYPTA 242
187251745 153 DTPPRSSIGFVRELEAKIKEY-----------GAGQIATVMGRYYAMDRSEDWNLTDKAYALITEGKAvRsA---KSAEE 218
159897411 220 AIEQAY-LR----D-ArGDEFIEATVITdsaGV---ALPRISTGDVVICFNFRADRVRQITRALM--QS-DL--N--TMI 283
294827652 239 TFRSEN-PK------I-IDQYLPSFVIsd-nGK---PVGKIQDGDSVVFTNFRGDRAIEISLAFT--EK-NF--D--KFD 299
45656283  243 TFRSEN-PK------I-IDQYLPSFVI----SDngkPVGKIQDGDSVVFTNFRGDRAIEISLAFT--EK-NF--D--KFD 303
189910040 241 TFRTEN-PS------V-IDQYLPGFVIGdsiGD---PIGKILDNDSVVFFNFRGDRSIEISRAFTeeNLtQLnrK--RFP 307
183219916 241 TFRTEN-PS------V-IDQYLPGFVIGdsiGD---PIGKILDNDSVVFFNFRGDRSIEISRAFT--Ee-NL--T--QLN 302
116327026 239 TFRAED-PK------V-IDQYLPSFVI----AEngnPIGKIQDGDSVVFTNFRGDRAIEISLAFT--EK-NF--D--KFN 299
116332315 239 TFRAED-PK------V-IDQYLPSFVI----AEngnPIGKIQDGDSVVFTNFRGDRAIEISLAFT--EK-NF--D--KFN 299
21225111  222 AHSAVH-SS------ErGDEWVPASVLT---EA---GDARVADGDAVLWFNFRSDRIQQFADRLH---------E--HLT 277
154251927 243 YLDQCY-RK----G-V-NDDRIPPSIAS--------SYRGIRQDDAILLVNLQADQAHGLLGALI--DPaAT-----GLA 300
187251745 219 AVQISYdTDktpdGtEmTDEYVAPAVIN--------GYKGAKDGDSVIFFNFRQDRAIQLTRAFI--DA-DYpgKreKFV 287
159897411 284 QewyanqaeqglqlpttiwqrpeQVSNL--HYVTMTQYDATFP--YAIAYP-PHYITEPLAKVIADAGKRQYHSAETEKY 358
294827652 300 R-----------------------GPLPnvLYAGIMQYDGDLKlpERFLVA-PPAIDRTLGEYMASSNIPQYALSETQKY 355
45656283  304 R-----------------------GPLPnvLYAGIMQYDGDLKlpERFLVA-PPAIDRTLGEYMASSNIPQYALSETQKY 359
189910040 308 K--------------------------V--EFAGMMQYDGDLFipKQYLVA-PPAIDRTMGEYFANEGIAQYALSETQKF 358
183219916 303 R-----------------------KRFPkvEFAGMMQYDGDLFipKQYLVA-PPAIDRTMGEYFANEGIAQYALSETQKF 358
116327026 300 R-----------------------GPLPdiVYAGIMQYDGDLKlpERFLVA-PPAIDRTLGEYMANSKIAQYALSETQKY 355
116332315 300 R-----------------------GPLPdiVYAGIMQYDGDLKlpERFLVA-PPAIDRTLGEYMANSKIAQYALSETQKY 355
21225111  278 A----------------------SGRTV--NMVSLAQYDTRTA--IPALVK-RADASGGLADELQEAGLRSVRIAETEKF 330
154251927 301 Ak---------------------APSLS--GVYSLVRLASPLGaeVEPLFE-AMSFKGSLAETIAQAGLSQLTLTETAAE 356
187251745 288 K--------------------------V--VFCGLTKYYDAFEfnALPSMTdGGSMNNLLGQVLADNGKTQLRIAETQKF 339
159897411 359 PHVTFFLNGRREEPFAG--EDRVMAASPK-VATYDLQPEMSAEEVAAKLLDAVNSQIYDFLVVNFANPDMVGHTGVIPAV 435
294827652 356 GHVTYFWNGNKSGYFDQ--NSEEYREILSdVIPFDQSPEMKALLITEALEKALNENKQDFYRVNYANGDMVGHTGNYLAT 433
45656283  360 GHVTYFWNGNKSGYFDQnsEEYREILSD--VIPFDQSPEMKALLITEALEKALNENKQDFYRVNYANGDMVGHTGNYLAT 437
189910040 359 GHVTFFWNGNKSGYFNQ--NLETYEEIKSdIIPFDQKPEMKAKEITDNLVLALTSHKFPFLRVNYANGDMVGHTGNMDAT 436
183219916 359 GHVTFFWNGNKSGYFNQ--NLETYEEIKSdIIPFDQKPEMKAKEITDNLVLALTSHKFPFLRVNYANGDMVGHTGNMDAT 436
116327026 356 GHVTYFWNGNKSGYFDQnsEEYREIQSD--VIPFDQSPEMKAFLITETLEKALNENKQDFYRVNYANGDMVGHTGNYPAT 433
116332315 356 GHVTYFWNGNKSGYFDQnsEEYREIQSD--VIPFDQSPEMKAFLITETLEKALNENKQDFYRVNYANGDMVGHTGNYPAT 433
21225111  331 EHVTYYINGRDATVRDG--EEHVRITGEG-KADYVAHPHMNLDRVTDAVVEAAGRVDVDLVIANLANIDVVGHTGNLAAT 407
154251927 357 ASLWNFARGGAKALFPG--ETVLVTDTPP-LAQAEKKPELASAAITEELLAALKKGEHDVITANFSNAAILGRTGNIRAT 433
187251745 340 KHVTSFFNGKLIKPFKG--EDRIELKGRFdPATFAEHPEMEAYLVADETVKQINSDKYDFILVNFANCDMVGHTGNMKSV 417
159897411 436 VKACETVDRCLGQVVPAVVAQGGAAILIADHGNAEQMI-----------DPQTGGPH--TAHTTNLVPCILVA-DPatgl 501
294827652 434 VQAMEFLDGCVERLWKTCEKQNIVLLVTADHGNADEMFqldkkgnvekdSHGNPIPK--TSHTLNPVPISILD-PEnkir 510
45656283  438 VQAMEFLDGCVERLWKTCEKQNIVLLVTADHGNADEMFqldkkgnvekdSHGNPIPK--TSHTLNPVPISILD-PE---- 510
189910040 437 VKGLEYLDLCLDRIKKICDETNTVLCITADHGNADEMYqldkkgnaqtaKDGKPVPK--TSHTLNPVQFVLYD-PQgkiq 513
183219916 437 VKGLEYLDLCLDRIKKICDETNTVLCITADHGNADEMYqldkkgnaqtaKDGKPVPK--TSHTLNPVQFVLYD-PQgkiq 513
116327026 434 VQAMEFLDGCLERLWKACEKQNIVLLITADHGNADEMYqldkkgnveknSQGNPIPK--TSHTLNPVPFSILDpERk--- 508
116332315 434 VQAMEFLDGCLERLWKACEKQNIVLLITADHGNADEMYqldkk--gnveKNSQGNPIpkTSHTLNPVPFSILD-PE---- 506
21225111  408 VTACEATDAAVDQILQAARNSGRWVVAVGDHGNAERMTkq--------aPDGSVRPY--GGHTTNPVPLVIVP-NRtd-- 474
154251927 434 VEAIEAIDKCLGKIAAQVDKRGGTLVLCGMYGKAEMML-----------DPETGGAW--RGTTTSDAPLIIIG-GP---- 495
187251745 418 IKAVEVVDECTGKITKAALDKGYTVLITADHGNAETMW-----------DVKTNMPK--TAHTCSLVELIYVS-KDa--- 480
159897411 502 treqiSLRA--------GGRLADLAPTILDLLGLQKAAAMTGTSLI--E 540
294827652 511 ---fnskLS--------NPGLANVAATILDVMGYETPEGYH-PSLIqnE 547
45656283  511 -----NKIRfns--klsNPGLANVAATILDVMGYETPEGYH-PSLIqnE 551
189910040 514 ---lnstIT--------EKGLANVAATMMDLLGFIAPDGYH-PSLInrN 550
183219916 514 ---lnstIT--------EKGLANVAATMMDLLGFIAPDGYH-PSLInrN 550
116327026 509 ----iQLNSnf-----lNPSLANIAATILDVMGYETPEGYH-SSLIqn- 546
116332315 507 -------RKiqlnsnflNPSLANIAATILDVMGYETPEGYHSSLIQn-- 546
21225111  475 ----tPAPTlp-----gTATLADVAPTILHLLGHKPGPAMTGRPLL--- 511
154251927 496 ------KGLel-----qDGTLADVAPTLLHLLGQSAPREMTGRSLIatS 533
187251745 481 -----ENIKle-----eLGCLGDIAPTILDILGVEQPKDMDRKSLVsk- 518
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