Conserved Protein Domain Family
DUF5525

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pfam17663: DUF5525 
Family of unknown function (DUF5525)
This is a family of unknown function found in Chordata.
Statistics
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PSSM-Id: 435956
Aligned: 6 rows
Threshold Bit Score: 1510.23
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006087959    1 MAEKRPRGTLGPMMYSKLPRLEVDSGPRHSLGPSAANQDPCNYKGAYFSCSMGGVPQTGSGQLASWTPYPTLYPTSVAGP 80  
XP_003901272    1 MAEKRPLRTLGPVMYGKLPRLETDSGPEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLASWTPYPPLYSTSMAGP 80  
NP_001020182    1 MAEKRPLGPLGPMMYGKLPRLESDLGPGHGLPLSAGNQDSCNYKGAYFSCPIGGTSKAGSERLASWTPYPSLYPSGVAGS 80   Norway rat
XP_007947138    1 MADKRPLGTLGPVMYGKLPRLEADSGPGHSLP-SAGRQDPCSYKGAYYSCPMGGAPKAGSERLASWTPYPPLYPTNMPGP 79   Orycteropus a...
XP_024837810    1 MAEKRPLGTLGPVMYGKLPRLEADSGPGHSLPPSAGNQDSCSYKGAYFSCPMGAPPKTGSERLAPWTPYPPLYPTSMAGP 80   cattle
XP_022268379    1 MAEKRPLGTLGPVMYGKLPRLEADSGPGHSLPPSAGNQDPCSYKGAYFSCPMGSAPKAGSERLASWIPYPPLYPASMAGP 80   dog
XP_006087959   81 PLREDNLLTSCLLYRPPAGSSEKVQDSGPVELLPFSPQTHSYSGPPLAAPKPVYRSPLCYGLSTCLGEGAAKRSLDVDWT 160 
XP_003901272   81 PLRTDNLLTNCLFYRSPAEGSEKMQDSSPVELLPFSPQGHSYPSPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWT 160 
NP_001020182   81 PIRGDSLLTNCLLYRPPTEGSEKMQDSS--ELLPFGPQAHSYPGPPLAAPKPVYRSPLCYGLSTCLGDGAAKRPLDVDWT 158  Norway rat
XP_007947138   80 PLRADSLMSNCLLYRPPTEGSEKMQDSGPVELLPYNPRAHSYPGPPLAAPKPIYRNPLCYGLSTCLGEGVAKRPLDVDWT 159  Orycteropus a...
XP_024837810   81 PLRANNLLTSCLLYRPSTESSEKVQDSGPVELLPFGPQSHSYPGPPLAAPKPVYRSPLCYGLATCLGAGAPKKPLDVDWT 160  cattle
XP_022268379   81 PLRTDNLLTSCLLYRPPAESSEKVQDPGPVELLSFGPQSHSYPGPPLAAPKPVYRNPLCYGLSPCLGEGAAKRPLDVDWT 160  dog
XP_006087959  161 LVTGALLPPANPHCSLTLAPGKGQSLDGTFLHGVPVGGSGKDS-SGSFSPRQAFLDKYQTSHSTGFLASKYAGSYSGDPK 239 
XP_003901272  161 LVTGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAGGSSKDS-SGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSK 239 
NP_001020182  159 LVPGPLLPSADPPCSLATAPGKGQPLDGTFLRGLPSGGPGKDS-SLTFSPCQTFLEKYRTVQSTGFLASKYPGPYSGDPK 237  Norway rat
XP_007947138  160 LVTGSLLPPADPPCSLAPAPGKGQPLDGTFLHGVPAGGSGKDSsM-SFSPCQAFLEKYQTIHSTGFLPSKYANPYSGDPK 238  Orycteropus a...
XP_024837810  161 LVTGSLLPPVGPSCSLPPASGKGQFLDGTFLRGVPAGASDKDS-SVSFSPCQAFLEKYRALHGTGFLASKYASPYSGDPK 239  cattle
XP_022268379  161 MVTGPLLPPADPPCSLTPAPGKGQSLDGTFLRGVPAEGPGKNS-V-SFSPCQAFLEKYRTIHGTGFLPSKYAGPYSGDSK 238  dog
XP_006087959  240 QGLSEGLpNPWTQLAQPLGPAYQDTVPSPYPLPHPPQALSCPPACHYPEKQSSYSSVPPPQPLGAHKGVGYLTGGLNSPY 319 
XP_003901272  240 QVMSEGP-SPWTQLAQPLGPPCQDTGPTHYPPPHPPQALPCPPACRHPEKQGRYSPALPLQPLGGHKGTGYQAGGLGSPY 318 
NP_001020182  238 QAMSEGPsGPWTQLTQPLGPPCQDAVPAHYPLPPPPQALPCPPSCRHPEKQGSYGSLLPLPPLGAHKGAAYQAGGLGSPY 317  Norway rat
XP_007947138  239 QALPEGPpSPWTQLAQPLGPACQDSVPMHYPLSHTPQTLPCPQACRHPEKQASYSSVLPLQPLGTHKGAGYPPGGLGSPY 318  Orycteropus a...
XP_024837810  240 QALSEGPpSPWTQLAQPLGPACQDAAPPHYPLPHPTQPVPCPPACRHPEKPGSYSSVLPLQPLGAPKGAGYPAGGLNSPY 319  cattle
XP_022268379  239 QALSEGPpSPWTQLAQPLGPACQDTVPTHYPLPHPPQALPCPSACRHPEKQGSYGAALPLQPLGAHKGAGYPAGGLSSPY 318  dog
XP_006087959  320 LRQQTAQTPCMPPVGPDIYSYPSVPLPVPSPGLKLEPPLTPRCPLDFASQTPGFPYARDDHSFYGASPGLRGTLP--SQN 397 
XP_003901272  319 LRQQAAQTPYIPPLGLDTYPYPSAPLPAPSPGLKLEPPLAPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPP--SQN 396 
NP_001020182  318 LRQQAAQTPYMPPVGIDSYPYSSAPLPAPSPGLKLEPPLAPRCPLDFVPQTLSFPYARDDLSLYGASPGLGETPPshSQN 397  Norway rat
XP_007947138  319 LRQQAVQTPYVPPVGLDTYSYPSAPLPAPSPSFKLEPPLAPRCPLDFPPQTLGFPHNRDDLSLYGASPGLGGTPP--SQD 396  Orycteropus a...
XP_024837810  320 LRQQAIQTPYMPPVGLDPYAYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLGFPYAREDLSLYGASPGLGGMPP--SQN 397  cattle
XP_022268379  319 LRQQAAQTPYMPPVGLDTFSCPSAPPPAPSPGLKLEPPLAPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPH--SQN 396  dog
XP_006087959  398 SVQAMPQPSAFQRTCQPLPASQPCPEPVrpveKPVQEAEETIWLPSCRKE----Q-LNeHPGAPIVIGDSPDPRTPPALP 472 
XP_003901272  397 NVRAVSQPGALQRACQPLPASQPCSEPV----RPAQEAEEKTWMPSCRKEqlqpR-LSeHSGPPIVIRDSPIPCTPPALP 471 
NP_001020182  398 SVQPVPQPGAFQRTCQPLPAGQPCSEPMrpaeKPTPEAQEKTWLPSCRKEqlqsR-PSeRPGVPIVIRDSPVPRTSPALH 476  Norway rat
XP_007947138  397 SVRAVPQPGAFHRTCQPVPASQPHLERVrpteKPVQAAE-KTWLPSCRKEqlrsR-LDeHPGAPIVIRDSPVPRTPPALP 474  Orycteropus a...
XP_024837810  398 SVQALPKPGAFQRACQPLPASRPCSEPMrpaeKPVQEAEEKMWLPSCRKEhpqpRlDE-HPGAPIVIGDSPVPRTPPPLP 476  cattle
XP_022268379  397 SLQAvpqpxhtqracqPLSASQPCPEPGrpveKPAQEAEEKMWLPSCRKEqlqpQ-LDeRPGAPIVIGDSPVPHTPPGLA 475  dog
XP_006087959  473 ACGQEHPSLPQNQDTLPPGSPPMPIIDNVFSLAPYRDYLDVQTPEATPEPDPAP---------KDSHDKDSRGTLSTQEA 543 
XP_003901272  472 PCARECQSFPQKEGARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATaepdstpatNEFQDKGCRGTPPAQEG 551 
NP_001020182  477 PCAKERQSLPQKD-ARPPSSPPMPVIDNVFSLAPYRDYLDVQTPEPTVEQDSAPa-------tSKSQDKDCKETLPVQDG 548  Norway rat
XP_007947138  475 PCAQERQSLPQHKGTSPPSSPPMPIIDNVFSLAPYRDYLDVQAPEATSEPDQVPa-------tNESHGKDCKGTLPAQEA 547  Orycteropus a...
XP_024837810  477 PCAQERQSLPQNEGSLPPSSPPMPVIDNVFSLAPYRDYLDVPAPEAPAEPELAPa-------pNESHDRDCGRSLPAQEA 549  cattle
XP_022268379  476 PCAQERRALLQSDGALPPGSPPMPVIDNVFSLAPYRDYLDVQAPEDPAEPAPAPa-------pSGSPAKDGGAPLAAREV 548  dog
XP_006087959  544 PLGV---HCPLREEVALDLSVKKPMTEPLPIKVPSPRVH-SKLPVAVG----------VS-------GVGNTVSKP---- 598 
XP_003901272  552 PSGSkplRGSLKEEVALDLSVRKPTAEASHIKAPSPVEH-ARPTAAMD----------VP-------DVGNMVSDLpglk 613 
NP_001020182  549 ASRP---HRSLREEVALDLSVKKSMAEDVPVKVPSPEEH-NKPSETVD----------GS-------GIENTASGLpglk 607  Norway rat
XP_007947138  548 PLET---RCSLREEVALDLSVKKPVTEMSLLKVPSPV-VpAKPTDTLN----------VGntvtgmpGVGNIVLDLpglk 613  Orycteropus a...
XP_024837810  550 PSSE---HPSLKEEVALDLSVKKTTAEASPTKVPHPMGR-AKPTAAVDmpatgsnvsnVP-------GTGDTVSDPqglq 618  cattle
XP_022268379  549 PAEP---LCSRREEVALDLSVKRPVPEA-PIGAPSPAAP-PQPPAAPE----------AP-------GAGNALPELpdpa 606  dog
XP_006087959  599 ---------PGVSTTTETTPKTNFHSSVAFMFRKFKILRPAPLSATMVPSV----------------PTSVPASDQPAPT 653 
XP_003901272  614 kidteapglPGVPVTADAMPSTNFHSSVAFMFRKFKILRPAPLPAAVVPST----------------PTSAPAPTQPAPT 677 
NP_001020182  608 k-----mvteiPEVTAEATPRTNFHSSVAFMFRKFKILRPAPLPAAIVPSPptpvsvpaptpvpvpvPVPVPVPAQPASN 682  Norway rat
XP_007947138  614 nlvteapglPGAPVTTEATPRTNFQSSVAFMFRKFKILRPAPLPATVVPSV----------------PTSAPAPAPPALT 677  Orycteropus a...
XP_024837810  619 kavtevpepPGLPVTTEATPRTNFHSSVAFMFRKFKIIRPAPLPATVVPSV----------------PTLAPAPAQPVPT 682  cattle
XP_022268379  607 kaapeaagsPVPATADEAAPRTNFHSSVAFMFRKFKILRPAPLPAAPAPA-----------------PAPAPAAPPAAVP 669  dog
XP_006087959  654 STSVPTGLQILK-QPLPVACFDLALSSLPGI------------------------------------------SVVGpaP 690 
XP_003901272  678 PTSGPIGLRILAqQPLSVTCFSLALPSSPAV------------------------------------------AVAS--P 713 
NP_001020182  683 PPSVPMGLQILT-QPLPVACFNLALPSPPAI------------------------------------------AVASpaP 719  Norway rat
XP_007947138  678 PTSVPIGLKIIT-QPLPMACLNLALPSPPALavaspapapapapapamspapapappptpapvpgpapastqaSTLV--- 753  Orycteropus a...
XP_024837810  683 PTPVPPGLQMLT-QPLPMACFGLTLPSPPAV------------------------------------------AMASpaS 719  cattle
XP_022268379  670 PASVPLGLQILS-PPLPVACFNLALPSPPAV------------------------------------------ALAS--R 704  dog
XP_006087959  691 TLSPSPAPAR------------------APTP----ATSPVTVDSPEQHFAGLHESLCDAISGSVAHSPPEKLREWLEMA 748 
XP_003901272  714 APAPVPSPAPapaqapasardpapapvaGPAP----ASTSAPGDSPEQHFTGLHASLCDAISGSVAHSPPEKLREWLETA 789 
NP_001020182  720 ASAPPPS--Papa------------pasGPAPasaqVPTAAPVYS-EQHFTGLHTSLCDAISGSVAHSPPEKLREWLETT 784  Norway rat
XP_007947138  754 -------------------------------------------DSAEQRFAGLHASLCDAISGSVAHSPPEKLREWLEAA 790  Orycteropus a...
XP_024837810  720 MPAPAPSPAPapapa--------papvaGPSP----ASTPTTADSSEQHFAGLHASLCDAISGSVAHSPPEKLREWLATS 787  cattle
XP_022268379  705 ALAPAPAPAPapa------------paaAPA-----------ASSPEQHFTGLHASLCDAISGSVAHSPPEKLREWLATA 761  dog
XP_006087959  749 GPWGRAAWQDGQAVQGLLGKLLSQLQRFVCTQQCPFPHVVRAGAIFVPIHLVKERLFPGLPPASVDHVLQEHRVELRPTT 828 
XP_003901272  790 GPWGQAAWQDCQGVQGLLTKLLSQLQRFDRTHRCPFPHVVRAGAIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTT 869 
NP_001020182  785 GPWGQAAWQDGQGVQGLLGRLLSQLQKFVCTQQCPFPHVVRAGAIFVPIHLVKERLFPklPPASVDHVLQDHRVELRPTT 864  Norway rat
XP_007947138  791 EPWGRAAWQDCQGIQGLLEKLLSQLQSFVYAHQCPFPHVVRAGAIFVPIHLVKERLFPQLPPASVDHVLQEHRVELRPTT 870  Orycteropus a...
XP_024837810  788 GPWGRAAWQDCQGVQGLLGKLLSQLQSFVCTQQCPFPHVVRAGAIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTT 867  cattle
XP_022268379  762 GPWGRAAWQDCQAVQGLLGKLLSQLQRFVCTQQCPFPHVVRAGAIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTT 841  dog
XP_006087959  829 LSEERALRERALRGCTSRMLKLLALRQLPEIYPDLLGLQWHNCVRRQLGDFNTEAGFVPSSEAIMARDEPESLCLAQKSP 908 
XP_003901272  870 LSEERALRELALPGCTSRMLKLLALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTLARDEPESLALARKSP 949 
NP_001020182  865 LSEERALRERALHGCTSRMLKLLALRQLPDIYPDLLGLQWHDCVRRQLGGFDTEARALSPSEPTVTRDEPESQVLAGKLP 944  Norway rat
XP_007947138  871 LSEERALRDRALHGCTLRMLKLLALRQLPDIYPDLLNLQWRDCIRRQLGDLDPEAGAVPPSEPTMARDEPESLALAQKSP 950  Orycteropus a...
XP_024837810  868 LSEERALRERALHGCTSRMLKLLALRQLPDIYPDLLGLQWRDCVRRQLGDFNTEPGSVPSSESTMAREEPGSLDLTWKSA 947  cattle
XP_022268379  842 LSEERALRERALHGCTSRMLKLLALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGSVPSSEPTMARDEPESLALAWKSP 921  dog
XP_006087959  909 IPKARKPGRKLPTPGREKAEATAGGGSC-ASPAPYASTS---PTVRAHCRSLLETAWLTGLALPTWGHKaSGAALPSPCP 984 
XP_003901272  950 APKVRKPGRKPPTPGPEKGEAAAGEESCaASPTPAACASppgPTLKARFRSLLETAWLNGLALPTWGHK-SRPDRPSPCP 1028
NP_001020182  945 APKAKKPGKKPPTPGPEKTETTTGEGSCnPSPSSGASTSppgPTLRARFRNLLETAWLNGVALPTWGHKaSGADRPSPHP 1024 Norway rat
XP_007947138  951 PPKARKPGRKPSTPGLEKAEAASGEGSHdVSPTPAASTSppaPTLRARFRSLLENAWLNGLALPTWGHKpSGPDRPSPHP 1030 Orycteropus a...
XP_024837810  948 APKAKKPGRKPPTPGPEKAEATAAGGSRgASPTPAAGASlpgPTVKARFRSLLESAWLNGLALPTWGHKaSGPDRTAPRP 1027 cattle
XP_022268379  922 VPKARKPGRKPPTPGLEKAEAAPEEGARgASPAPAASTCpqgPILRARFRSLLETAWLNGLALPTWGHKaTGPDRSMPQP 1001 dog
XP_006087959  985 QLLGGQSHHL 994 
XP_003901272 1029 QLLDSQSHHL 1038
NP_001020182 1025 QLLGSQTHHL 1034 Norway rat
XP_007947138 1031 QLLRSQSHHL 1040 Orycteropus afer afer
XP_024837810 1028 QLLGSQSHQL 1037 cattle
XP_022268379 1002 QALGDQSHPL 1011 dog
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