Conserved Protein Domain Family
PALB2_WD40

?
pfam16756: PALB2_WD40 
Partner and localizer of BRCA2 WD40 domain
This domain is found at the C-terminus of partner and localizer of BRCA2 (PALB2). It is a seven-bladed WD40-type beta-propeller. It binds to the N-terminus of BRCA2.
Statistics
?
PSSM-Id: 435563
Aligned: 4 rows
Threshold Bit Score: 639.211
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_004945321  984 QKNTEAEqLTPvllDGLREENLQFISKLKDSSGSCAVDVSSVWWGAAGYRELCVVTACESSVSLWKPQAPDHWEKVYTWQ 1063
XP_023353382  847 QTKVRGD-PVEiwhDTLELGNLQLVSKLKNPSNSCSVDVSTVWWEVTGCKESCIITACEFTVSLWKSLDNWQWRKVHTWH 925 
ELK12100      861 QQPGIADiPAC---DSVVPGDLQLVSRLKDPSAPCAVDVSALWWDVAGLKEPCIVTACEYAVSLWKPLDTWQWEKIYSWH 937 
XP_005998537 1038 SPTCQGH-------SDTNEETLKLISTLKNHSHSCGVDLCSVWWDIDGRRRLNIVIACENSVSLWESLQENQWENTHTWD 1110
XP_004945321 1064 LGEIPVIQIIPVPDTCNLVCIALGNLEIGEIRLLLYSSENDSFKQSLVKSGNIKAVLGLRDGKLISSSRAMQEQQVEIVS 1143
XP_023353382  926 FTEIPVLQIIPLWDACNLVCVALGHLEIREIRLLFSSAEDECLKQSLVKSGNIKAVLGLRHKRLVCSNGTLHDHQVDLMT 1005
ELK12100      938 FTEVPVLQIVPVPDVCDLVCVALGNLEIQEIRALLCPSDGESGKQVLLSSGHIQAVLGLTKRRLASSRGTLCDQQVEVMT 1017
XP_005998537 1111 FTEVPVIQIVSIPEAINLICVALGKLEIGEIRTLFYSREEGTFRQSLLRSGDMKIVLGLTDRRVVSCNSGYRKQNVELIS 1190
XP_004945321 1144 LSETGRCKDRQTLMPPEETVLAFAEVEGVRDALVGTTAVNSVVVWNLKTGQLLKKMHIGYSYPASICHRAYSDSGLLFVV 1223
XP_023353382 1006 FSGSGRSKEKQTLMSPEETILAFAEVQGMQDALLGTTLMSNIVIWNLKTGQLLKKMQIGNAYQASICHKAYSDMGLLFVV 1085
ELK12100     1018 FAEDGGSKEKRFLMPPEETILTFVEVQGMQDALLSTTVTNSIVIWNLKTGQLLKKMHIGDSYQASVCHKAYSEMGLLFVV 1097
XP_005998537 1191 LSEEGRNEGTLTLMSPGESILAFAEVDGEKDALIATTDLYNIVLWNIKTGQLLQSISIGNSYPTSLCLKAFSDSGLLFAI 1270
XP_004945321 1224 LSHPHAKESELCGNPAFRVIAFNPKTARSTGVMFSSLPPGHTGR--YLEGEVKDAWAAAVLTSGAIAVWDLLLGCCTALL 1301
XP_023353382 1086 LSHPHGKEIESMGNPIFRLIVINPKTALSVDVRPYSLPQGHTGR--FLDGDVKDNLAAAVLTSGTIAVWDLFLGHCRALL 1163
ELK12100     1098 LSHPCAKESEPSGSPVFQLIAINPKTTLNVGVMLYCLPRGQTGRqvFLEGDVRDSSAAAVLTSGTVAVWNLLLGHC-AVL 1176
XP_005998537 1271 LCNQHNNKSESSLDSVLKLVAINPKKGHNSQVLAYTLPAGFRGQ--YLDGDVSGQTVAAVLTSGAIVLWDLLYGHCTAQL 1348
XP_004945321 1302 PPGSDSRWTLVRWSAAGAGLLAGRADGSVCVYR 1334
XP_023353382 1164 LPNSDGNWSFVKWSGTDSCLLAGQKNGSVFVYS 1196
ELK12100     1177 PPVSGQSWSFVKWSGTHSHLLAGRKDGSIFVYL 1209
XP_005998537 1349 APETDESWSLVRWANLDSCLLAGQKDGHVLIYE 1381
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap