3WYG


Conserved Protein Domain Family
PKI
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pfam02827: PKI 
cAMP-dependent protein kinase inhibitor
Members of this family are extremely potent competitive inhibitors of camp-dependent protein kinase activity. These proteins interact with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Links
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Statistics
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PSSM-Id: 460716
Aligned: 22 rows
Threshold Bit Score: 78.5406
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WYG_D        2 TDVETTYADFIASGRTGRRNAIHDILVSSASGNLNELALKLAGLDI---NKTEGEEDAQRSSTEQSGEAQGE 70 
O70139        2 MEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGELAL---EGAEGQAEGSTPDKEASSQPESS 70  house mouse
XP_015220181  2 MEVESAYSDFISCDRTGRRNAVPDIGGEGAKVGTGELTKDMAQMDL---KAPEEEGTIASQSSQGEVAGSQE 70 
XP_015210495  2 TDVEATYADFIASGRTGRRNALHDILGAQGDLEGGDLSLKLSELDLgktGEGDGGEKSQASSTERPPSAQEE 73 
Q5BKM1        2 TDVESTYADFIASGRTGRRNALHDILVSSSSGNTSELALKLSELDI---SKSEGDENEKENPSDKTPEEKNQ 70  tropical clawed frog
Q90641        2 TDVESTYADFIASGRTGRRNALHDILVSSPGGNSSELALKLSELDI---NKAEGEGDAQRNPSEQTGEAQGE 70  chicken
XP_007486990 16 TDVETTYADFIASGRTGRRNAIHDIIVTSSTTNTTDVSVKLSDLDI---NKPDGEGDGQKSPPEQSGDNQGG 84 
P63248        2 TDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDI---NKTEGEDDGQRSSTEQSGEAQGE 70  house mouse
NP_001289079  2 TDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSV---SEDEGAEGGEVSSSKALLESQEA 70 
Q5SPN9        2 TDVEPVVSDFAATGRTGRRNALPDILGSTAGPGAADLPDKLAELTV---GDDGEQGGESSSSTDPPKESTEG 70  zebrafish
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