5EIK,5EGI


Conserved Protein Domain Family
TRIC

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pfam05197: TRIC 
TRIC channel
TRIC (trimeric intracellular cation) channels are differentially expressed in intracellular stores in animal cell types. TRIC subtypes contain three proposed transmembrane segments, and form homo-trimers with a bullet-like structure. Electrophysiological measurements with purified TRIC preparations identify a monovalent cation-selective channel.
Statistics
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PSSM-Id: 461583
Aligned: 34 rows
Threshold Bit Score: 208.982
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5EIK_A               51 AISFSRKHPFSCWLSCMLMSFAGSFLSCFLLGEPIISPLKQHADILLGSIVWYLVFYSPFDVVFRLATWFPVKLGLSVLK 130 Caenorha...
ESO07281             50 QVLFSRAHPLCDWFGNLLMCFAGSFLGNFLLGEPLITPLQNTKEIVIITVVWYLINYSPFDVFFNFINLLPVKFILNLLK 129
XP_015782535         42 GHTFSRKHPFACWISSMVNIFASPILANFLLGEPILSAFKSSNQVMLATIVWYLIFYSPFDCIYKVTKFMPCKVILASMK 121
XP_015783347         42 AHPFTRKHPFSCWLSSMINIFAGSILANFLLGEPVIAAFKNPNQVLLATVIWYLIFYSPFDVIYKIFKFMPCKVVLAAMK 121
XP_015788302         73 AHKFSRRHPFSCWASTMLSFFSGSLLANFFLAEPLTDVFKSSQTVVLATLTWYIVFYSPFDIVCKLISLRPCYILLDCAR 152
XP_001983406        156 AKRSTKQRPFVLWLTNLLVTYAGEILVNMLLGTLPLKPLSNVQDILLCSAAWYLIFYSPFDCAHSLACSVLFRLLAAPVT 235
XP_001623406         41 GTGFAQSNPLACWISAVISNFAGSFLISFFLGLPMVLPLKDVRAVAAMTTIWYLVFYCPFDIFNKFFMLQPAWLSLVVLK 120
XP_002046225         45 eRSCLEMRPFVLWLTHILVSYSGDILVNLLLGTLPLEPLSNYHDVMLSTFAWYIIFYSPFDVAHSVARTTPFRCLATPVA 124
WGS:AAPU:GI16529-PA  38 grrSQKMRPFTLWLTHILLSYAGDILVSLLLGTLPLEPLNNAQDVALCTAAWYIVFYSPFDVAYVVARTAACRCLIAPVT 117
CUT99039             43 SGAFSRKHPFACWFATMLMCFGGAILGNFILGEPIFACFDDHRAVLTATAVWYLINYSPFDVVYKIYSLFSVRLLVCVMK 122
5EIK_A              131 EVQRTHKIAAGVKHAVRIY-PESYLVQILVGVAKGAGSGVVKIVEQLARGTWHPTNHEILRPSFTTKACVIASIVFTLE- 208 Caenorha...
ESO07281            130 EVRRVNKVDQGINFALKVM-PDTHIVPLAFGILKGTATNHMKVFHRLTCGVWQPSSIELLNPSIVTKTTFLGALLLFLH- 207
XP_015782535        122 EIVRCKKIHDGVSHASKIY-PDGYLIMTIVGTAKGNGASFIKVLERLIRGVWTPNAMEMITPTFPTKASIVASIIFIID- 199
XP_015783347        122 EVIRCKKVHDGVTHASKIY-PNGYIIMICIGTVKGNGSGFMKLMERLMRGTWTPNAFELLSPTFPTKASIVASIIFIID- 199
XP_015788302        153 EILRAKVVYTGVTHTARIY-PGNYAIIIFIGALRASGGCFLRPLDRLFRGIWTPNIIEMLNPSYPTKTALLASAIFTVN- 230
XP_001983406        236 AISQILHIERGVQLAVKMYgNNAMVPILIVGTVIGSGAEFLKPVAALFINRCQLNNAAYVKLSTNSKVSLGITWLFLLQl 315
XP_001623406        121 EAHRAKAILGGVSMGLEHY-PTDLLVVVLVGIFKGAGALLVQPVAAVVQGSLDVTSHEALKPSFTTKASIVASILYTLV- 198
XP_002046225        125 ALSQVLHIERGVHLASKVYgKNSLVPVIIIGTVIGSGAEFLKPVAALLINRCQMKPAAYIKLSTNSKLAIAISWLYLLQl 204
WGS:AAPU:GI16529-PA 118 ALNQVLHIERGVQLATKTYgRTATLPILIIGTVIGSGAEFLKPVAALLINRCQLQNVAYVKLSTNSKLALLVTWLYLVQl 197
CUT99039            123 EVQRSKKISLGVSHAYHDY-PHSAVTCILVGLLKGTGYLEMKIFARLVRGVWLPASTEFLHPSFTTKISLLSAIVFYCD- 200
5EIK_A              209 -RHSMYVTAPHDLVYLCVVGFFIYFKLA 235 Caenorhabditis elegans
ESO07281            208 -RSGHLSFIPEPILYLFIVVFFLNIKLL 234
XP_015782535        200 -KKTDWISIPHALIYFGVVIFFVYFKLS 226
XP_015783347        200 -KKTDWISVPHALVYFGIVIFFVYFKLS 226
XP_015788302        231 -KQSDWINISTPLVYLAVVSLLIYLKFS 257
XP_001983406        316 nKSRLLLGLGKNQLQLYVLFMLMCFKYM 343
XP_001623406        199 --LKGIISISTECLCFGVFLVFALIKVS 224
XP_002046225        205 nGSQLLFGLSRCQLQLYALLALMCFKFl 232
WGS:AAPU:GI16529-PA 198 nHSRLLLGLRRCQLQLYVLLALTIFRIl 225
CUT99039            201 --LLDLIPLSRHQLFLAVVGVLVYMRVA 226
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