Conserved Protein Domain Family
zf-CCHC_3

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pfam13917: zf-CCHC_3 
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
Statistics
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PSSM-Id: 404753
Aligned: 19 rows
Threshold Bit Score: 42.7764
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7QJY9        11 ENVRAACKKCGFPGHLTYQCRnyltvdpqsqA--------Vvp---vqKRPGSESPEQNY 59  Anopheles gambiae str. PEST
XP_001696858  27 NRQQARCQRCLQIGHYTYECK----------Nea----ayA-------ARPSRTQQLKQG 65 
XP_003900143  39 NKQHVRCQKCLEFGHWTYECT----------Gkr----kyL-------HRPSRTAELKKA 77 
XP_001844226 102 FPKGVRCQKCLEFGHWSYECK----------Gkr----kyV-------HRSSRTQLLKKN 140
A0E2U0        31 DAAAVRCQRCLKYGHLTYECK----------Nen----vyL-------YRPSRTMQFKEK 69  Paramecium tetraurelia
ESS29615     236 AIYNIACQRCGGKGHMAHECYn--------tGgn----kyEmleeerpARPEHTAVIQPK 283
EFC44157      17 EGGGGFCQKCFTEGHWTYQCK----------GekapsttyT-------KRLSHTEKLEMM 59 
EEY70243      44 SSVAAMCQKCLRRGHWTYECK----------Nga----vyV-------QRPSRSQQLRNP 82 
XP_001759262  94 FGGSQQCQKCFQMGHWTYECK----------Ndr----vyI-------SRPTRTQQLANP 132
XP_015574660  90 AGGTAQCQKCFQTGHWTFECK----------Ner----vyM-------ARPSRTQQLKNP 128
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