2NPM,3EFZ


Conserved Protein Domain Family
14-3-3

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pfam00244: 14-3-3 
14-3-3 protein
Statistics
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PSSM-Id: 459729
Aligned: 149 rows
Threshold Bit Score: 165.385
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NPM_A        34 MAKLAEQ-AERYDEMAKYMKDVVEArqeSEELTVEERNLLSVAYKNAVGSRRSSWRIIS---Sv-EQKehsrnaEDASK- 107 Cryptosporidium...
XP_001316022  11 MARVADQ-AERHEDVIQYIKEIIDI---DPKLSLDERNLLSVAYKALTGNRRTALRSVN---AflEDPsiq-gaKEREN- 81 
EAX92702      11 MATAMSQ-AERYGEMLSYMKRAVEI---NPVLSNDERQILVNAYKFTISPKRRGIRNIF---RseMDDstanlsEQTQA- 82 
XP_001580564  11 MARILSDlPNKALDMVKYVKRAIEL---NPILDASERSLLMVSYKTLISTRRQGLRHLL---Lq--DDevsessDVCKH- 81 
EAY01333      10 MAQILGQtPSKAKEMVNYMKRAVEL---NPILDTSERTLLSVGYKNLITSRRQGIRHLM---Qq--EDemegltVPCKE- 80 
Q4KXQ3        11 MAQIYDQ-TDRHQDMVDTMKKVIEL---SADLTNDERNLLSVAYKNIIGSRRNGLRMIA---AilEHEdgr-gnTQRVA- 81  Trichomonas vag...
XP_001320232  10 LIEILDS-TSRHDDMIKQMKRIIEL---EPKLSTEERNFLSVSYKNVTDVRRNSLNEIS---QylATDal--qhPNAIP- 79 
EAX89480      11 TAQILDQ-TNLPEEMITLMKRVIEL---NPDLNDDERNLLSVAYKNSINQTRKGLREIK---AyiQEQqndgqyPNRLN- 82 
EAY04588      10 LAQVAMK-AGQPNDAILYIKQALKT---KTDLTKEEIDFFAHTYKKAINSPRNALVAMD---N-----------QLQLQs 71 
XP_001313091  16 TAKSLYK-AGICDQAMTSFKQAIDM---DARLNKKQTTFFNDLVQTIVNPIRAATKQLReseAfaQEKses--------- 82 
2NPM_A       108 -----MCGKYRSKVEAELTDICNDILTMLDKHLIPtaTSPDSKV-FYF-KMKGDYHRYISE-FSTGDSKQSSAEDALKAY 179 Cryptosporidium...
XP_001316022  82 -----RLIELRNSLIKELDDYCNSIVKFVDDKLLPaaDDAISKV-FYW-KLKADYFRYSVE-FKDEAARAQGSEAAKKAY 153
EAX92702      83 -----EVKSIKKQIITELVSLCEEFIDLINSKLLPvnTDPDSIV-FYN-KNKGDYYRYICE-ATDGNERIVATKRGMESY 154
XP_001580564  82 -----KIEQIKKDLVTELVNICNELFDLLDNTLIPktTDPESIV-FYQ-KLKADYYRYICE-AQTDEAFENAKQKAMESY 153
EAY01333      81 -----RIQKIKEELINELVGFCTELINLVDEVILPkvEDPESVV-FYQ-KLKADFYRYICE-AQTGHDLELSLENATKSY 152
Q4KXQ3        82 -----SLNAYRKVILGELEKYCNELIGLVDLSLLPaaKTAESRV-FYQ-KLKADYYRYICE-SRSDDEKTEPAQKAKECY 153 Trichomonas vag...
XP_001320232  80 -----YLQKTRAQIADELKNYCTDLISLVDEKLLPscSDEKSRL-FYI-RLKADYYRYLCE-AVEGEEREKSVISAQTLY 151
EAX89480      83 -----QLLEFKQQMFKELEAICNDLVQLVDDSLIPaaTTSEARV-FYE-GLKANYYRYVCEfIDDDDEKNTVAEKANQCY 155
EAY04588      72 pdvlkAIEEHRAVLIEEITNICQDILNIIDSTLIP--TTSNGKCiIYLnKLKGDYYRYLAEyASSKEIQEGHASRAKTCY 149
XP_001313091  83 --latLIHNETVKQFEKLKFTCHDVLSIIDQQIIPgnTDTEVKV-DMM-RLQADLYRYITE-FANDDEKSFFSNRAASVY 157
2NPM_A       180 KDATVVA-KDLEPTHPIRLGLALNFSVFHYEILNEPRAAIDMAKEA---FEMAIEQLDKLSEDCYKDSTLIMQLLRDNLT 255 Cryptosporidium...
XP_001316022 154 EEAMNLAk-DLSKANPQYLGLALNYSVFLYEIIGQKNEAIELADKS---FKEAVGLIDKLEEDEYSEATLILQLLKDNVQ 229
EAX92702     155 EVALEKSkVALQQYTPTALGLMLNYTVFLYEICDKKDVAVKMARET---VSLVSPIVEQNSASSLPEAKTILQLLNNNIS 231
XP_001580564 154 ESALSVSkQNLQSFTPTSLGLILNYTVFLFEIADKKQEAINLAQET---YQNCAPLIEQNTENSRAEASDIIRLLDENIK 230
EAY01333     153 KKALEVSkQNLQSYSPTSLGLILNYTVFLFENAKKQTDAVRIAQET---YQTYAPIIEQNSEKSREEAAQIIKLLDENIK 229
Q4KXQ3       154 EAAMQISnAEIAQYRPTSLGLILNYSVFLYEIIGEKQKAIDLAQKT---YNTCSSNVEKNSDNSYSEATMILQLLRDNVQ 230 Trichomonas vag...
XP_001320232 152 NEAIEITkKEYPRYSPTYLGLFLNYSVFLHETLHAKAEALQTAMEI---SSLPTDEIEQNDEAASIEARTILNQNLENIG 228
EAX89480     156 NSAIEIAkNDIPPYKPSYLGLLLNYSVFLYEILDKKEEAIELSQRT---YNESSPLVEENSESSFNNATMILNLISENLA 232
EAY04588     150 EAALLSVnDEMVVSDPLNLGLILNYAVFQYEILNLHDDAIDKLDTA---FNEAIRFLEELPEDQYNEAAIMLQLMRDNLS 226
XP_001313091 158 EQAYKIAsNKLPSHSTSRLALVLNRAILLANVLGHISEAVDLVEYEvglLNQGNTE---LSETSYQQAMIFSRSLGKLLL 234
2NPM_A       256 LW 257 Cryptosporidium parvum
XP_001316022 230 LW 231
EAX92702     232 LW 233
XP_001580564 231 MW 232
EAY01333     230 LW 231
Q4KXQ3       231 LW 232 Trichomonas vaginalis
XP_001320232 229 VW 230
EAX89480     233 IW 234
EAY04588     227 LW 228
XP_001313091 235 RW 236
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