Conserved Protein Domain Family
Ribosomal_L19e_E

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cd01417: Ribosomal_L19e_E 
Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an extended segment. It is located toward the surface of the large subunit, with one exposed end involved in forming the intersubunit bridge with the small subunit. The other exposed end is involved in forming the translocon binding site, along with L22, L23, L24, L29, and L31e subunits.
Statistics
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PSSM-Id: 238705
Aligned: 20 rows
Threshold Bit Score: 196.417
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:putative intersubunit bridge
Evidence:
  • Comment:L19 participates in forming the bridge between large and small subunits in the ribosome
  • Comment:by similarity to structure 1JJ2_O

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                     
NP_585864   4 EERVRRLASDILNCGKKKLWLDNNEIERLNGASTREQIKQLIKDNVIIMKQDKHTSRGRCRKRLEAKKKGRHMGTGKRFG 83  Encephalitozoon cu...
NP_703805  17 LTLQKRLAASVLKCGKNKIWMDPNEISEISLANSRFSIRKLYKEGLILKKPQKVHSRARVRLYKLAKRKGRHMGIGKRKG 96  Plasmodium falcipa...
EAA38237    4 LRLQKRLAADVLKCGKRRVRFNPAHEKYIEQASSREAIRSLIESKIIAKLDIKGSSRGRIRARHAAKRLGRHSGHGKRRG 83  Giardia lamblia AT...
EAA30828   47 LRTQKRLASSVLGVGQRKIWLDPNEVSEISNANSRQTIRKLVADGLIIKKPVTMHSRSRARELNLARRIGRHRGFGKRKG 126 Neurospora crassa
P05735      4 LRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKG 83  baker's yeast
AAP05800    4 LKLQKRLASSVLKCGKGKVWLDPNEVNEISMANSRQNIRKLVKDGFIIKKPQKIHSRSRARRAHEAKQKGRHSGYGKRRG 83  Japanese rice
P14329      4 LKLQKRLAASILKCGKGRVWIDPNEIADVAMANSRDNVRRLIATGFIMRKPVVVHSRSRAREHNAAKRLGRHRGAGNRLG 83  Dictyostelium disc...
P49693      4 LKLQKRLASSVLKCGKRKVWLDPNEGSDISMANSRQNIRKLVKDGFIIRKPTKIHSRSRARQLNIAKRKGRHSGYGKRKG 83  thale cress
AAG53669    4 LKLQARLAADILRCGRHRVWLDPNEASEISNANSRKSVRKLIKDGLIIRKPVKVHSRSRWRHMKEAKSMGRHEGAGRREG 83  Trypanosoma cruzi
EAK82415    4 LRTQKRLAASVLGCGKRKVWLDPAEQNDIGNANSRANIRKLIRDGQIIRKPVVGGSRSRARATAAAKRAGRGTGQGHRKG 83  Ustilago maydis 521
Feature 1                                 ## #####                   ###########              
NP_585864  84 TANARMPQKKIWMKKIRAMRAMLKEMRANGEITKEDFRVFYKQAKGHLFKHRFHMKDCIIKRKADEQRAKELAEQAKAL- 162 Encephalitozoon cu...
NP_703805  97 TKNARTNQKTLWIKRQRVLRRLLKRLRDSKKVDRHLYHSFYLKCKGNQFKNKRTLIEAIQREKNETLKKKAIADQLEAK- 175 Plasmodium falcipa...
EAA38237   84 TREARMPSKTLWIQRQRVLRRLLSRYRDDEKIDRHLYETLYAKAKGNMFKNKRVLLEHIVGMQKEQELEKKKKEELEQRr 163 Giardia lamblia AT...
EAA30828  127 TADARMPEQVLWMRRQRVLRRLLVKYRASGKIDKHLYHELYHLAKGNTFKHKRALVEHIHRAKAEKAREKAIKEEMDAK- 205 Neurospora crassa
P05735     84 TREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEAR- 162 baker's yeast
AAP05800   84 TREARLPTKILWMRRMRVLRRLLRKYREAKKIDKHMYHDMYMKVKGNMFKNKRVLMESIHKSKAEKAREKTLSDQFEAK- 162 Japanese rice
P14329     84 TREARLPSKILWIRRIRVLRRLLKKYREAKKIDKHSYRELYLKAKGNVFKNKRTLIEYIVKSKTEKLREKLIQDQAQAR- 162 Dictyostelium disc...
P49693     84 TREARLPTKVLWMRRMRVLRRLLKKYRETKKIDRHMYHDMYMKVKGNVFKNKRVLMESIHKSKAEKAREKTLSDQFEAK- 162 thale cress
AAG53669   84 TREARMPSKELWMRRLRILRRLLRKYREEKKIDRHIYRELYVKAKGNVFRNKRNLMEHIHKVKNEKKKERQLAEQLAAK- 162 Trypanosoma cruzi
EAK82415   84 SSEARMPTKVMWMRRQRVLRRLLRKYRESGKIDKHLYHELYLKSKGNVFKNKRVLMEHIHKAKAEAARSKHLADQMEAR- 162 Ustilago maydis 521
Feature 1           
NP_585864 163 -NLSNR 167 Encephalitozoon cuniculi
NP_703805 176 -RLKAQ 180 Plasmodium falciparum 3D7
EAA38237  164 kKAEQR 169 Giardia lamblia ATCC 50803
EAA30828  206 -RARTK 210 Neurospora crassa
P05735    163 -RLKNR 167 baker's yeast
AAP05800  163 -RAKSK 167 Japanese rice
P14329    163 -RNKNK 167 Dictyostelium discoideum
P49693    163 -RAKNK 167 thale cress
AAG53669  163 -RLKDE 167 Trypanosoma cruzi
EAK82415  163 -RMRNK 167 Ustilago maydis 521

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