Conserved Protein Domain Family
Rer1

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pfam03248: Rer1 
Rer1 family
RER1 family protein are involved in involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment. The C terminus of yeast Rer1p interacts with a coatomer complex.
Statistics
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PSSM-Id: 460860
Aligned: 117 rows
Threshold Bit Score: 171.173
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5KPE9        72 NTNVWAR---KWQGLLDRSTPHVLERWLVTLGLFLLFALNVILRQGWYIVCYALAIYILNLFLAFLQP-RFDP--SLAE- 144 Cryptococcus ne...
XP_001611309  18 lQNRLAFfqrGRQAILDYISTHIVLRWIYFVILFYVFWYRVIAYASHFVIAYMYAVYALNSVIRFLTPlDF------QDl 91 
Q57XM3        16 FTDNIKM---TWSRLLDQTVPHRPLRWVMFVFMLSLYILRVYFCGGFYVISYVLGIHLLFLLVQVITP-LADE--DLGSe 89  Trypanosoma brucei
Q4D9J0        16 FKRKAHL---TYQRYLDKTVPHRAMRWAMFGFLLMFYILRVFFHGGFYVITYGMGIHLLYLLLLLVTP-LAED--EFAEd 89  Trypanosoma cruzi
Q4QBT9        16 FLRKARV---TYKRYLDASVPHCALRWCFFAFLAILYVARVVTFGGFYVITYGLCIHLLYLLLLLITP-LSDP--DESEg 89  Leishmania major
EAX97405      15 DKQEALM---RFESLLYQIKPYLWQRWCAFGFMMFLFLLRVFTWHAYYYIVYIIGLYLLSCVVEFISP-KRDP--ELYGe 88 
EIJ89068       1 --mKLQH---LIQSYADMSVGMIKQRWCAFLFLFVVFVWRIILTGGYRLVAYCLFLYFLHCFIGFCTPvDS--------- 66 
EJW04654       1 --mnIKT---IIQIYLDKLAPMKKERWVFLILFMILYFLRIIVIQQFFLITYCVSIYLLHGLIEFLTPkEE--------- 66 
EPR78825       1 --meLTT---LFNHYLDKITPKRLERWIGFTLLEIFFLLRIYILNSHHLVTYIVSVYLLHSLVMFLTPrDE--------- 66 
A0CS82        15 AIHRVKV---NYQKKIDRYILYKKSRWFFNLLLMLLYAYRIQNIGGFYIVTYIYCVYQLQLLIDYFTPlGL-PpvNLEDe 90  Paramecium tetr...
Q5KPE9       145 DlaadDVEEGapGLPgaGpaktpgglkgllngfsngEEDE-----------------EFRPFIRRLPEFKFWYSATKANA 207 Cryptococcus ne...
XP_001611309  92 CaaheAAHGGt-ILP---------------------SSEGnrteitlekmrhpdtvyEFRPFLRDMNEFTFWLCLVRATY 149
Q57XM3        90 G-----------QLP--Hta---------------aSPDE-----------------EFRPFVPRMQEFVVWCSMMKSVL 124 Trypanosoma brucei
Q4D9J0        90 S-----------PLP--Rta---------------aGNDG-----------------EFRPFVPRVQEFVVWKSMFRVVS 124 Trypanosoma cruzi
Q4QBT9        90 T-----------PLP--Mt----------------hTDSD-----------------EYRPFMPKVQEFVVWKQMFTVLF 123 Leishmania major
EAX97405      89 E-----------VLP--S------------------AKDG-----------------DYKPFVRRLPEFQFWCCCMPASV 120
EIJ89068      67 ------------ELP--Dpfdieeee--tvisspikKSGD-----------------ESKPFIRRLPEFEYWLQSIKACF 113
EJW04654      67 ------------NIP--Dpfdnfed-----dvyeqtTLDD-----------------EYRPFIRRMPEYKFWMFCMQLIG 110
EPR78825      67 ------------SIP--Dpfeefde----yeeyipqTVDD-----------------EFRPFLRRLPEFDFWCRSMGLIL 111
A0CS82        91 EedddQFQNDfsELP--Ttlsn-----------kneLNDK-----------------EFRPLLRTTSEFKVWQKSVFSVI 140 Paramecium tetr...
Q5KPE9       208 IALLCTITRATDVPVYWPILLVYFFTLFGLTMRRQIQHMIKYRYVPFDLGkKARYG 263 Cryptococcus neoformans
XP_001611309 150 VALFCMLFDALDVPVFWPLLVVYFVGLFALTMREQLENMIKYKYVPFNIG-KRTYG 204
Q57XM3       125 VCTFLTLFRILDIPVFWPVLLLYFIFLTIIQVGERIRHMIRHRYVPWSAG-KPKFV 179 Trypanosoma brucei
Q4D9J0       125 ICLFLTLFNFLDIPVFWPILLLYFIVLTVTQMGSRIKHMMKHRYVPWNAG-KPKYV 179 Trypanosoma cruzi
Q4QBT9       124 VCLFLTMFSFLDIPVFWPILVLYFLALFATQVGGRVRHMIKHGYVPWNAG-KPKFV 178 Leishmania major
EAX97405     121 LACFFSLMP-FDLPVYAPLLFVYFIVVSVFVFRKRIMHMIKYKYVPWDTG-KQKYQ 174
EIJ89068     114 AGIVMTFFPVFNIPVFTPILIIYFCGLVYLTVIKIRKHMEKYKYNPFFNA-KKIYK 168
EJW04654     111 TAFMCTFFDFLDIPVYVPILIFYFIVIAALTAKNMHRHMKKYKYNPFFKA-KDVYV 165
EPR78825     112 FAWFTTFFSFFNITVYVPILILYFIFMIFLTAHKMYKHIKKYHYNPFFGD-KEQYG 166
A0CS82       141 FAYFCTYIPIWDIPVYWPFLFCYFFVIVGMSIRKYIKHMKKYGYTILDFT-KKK-- 193 Paramecium tetraurelia
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