Conserved Protein Domain Family
PDCD9

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pfam07147: PDCD9 
Mitochondrial 28S ribosomal protein S30 (PDCD9)
This family consists of several eukaryotic mitochondrial 28S ribosomal protein S30 (or programmed cell death protein 9 PDCD9) sequences. The exact function of this family is unknown although it is known to be a component of the mitochondrial ribosome and a component in cellular apoptotic signaling pathways.
Statistics
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PSSM-Id: 462101
Aligned: 21 rows
Threshold Bit Score: 510.405
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O61818               17 KATTAGADLPqSSQEIEvttpkSENVPAKSANAST-------------VYRPpyyrkphqhhepkhmlqeeFVNAGDASG 83  Caenorha...
XP_004058926          1 MAAARCWRPL-LRGPRL-----SLHTAANAAATATettcqdvaatpvaRYPP-------------------IVASMTADS 55 
XP_002639732         17 KASTAAd----IPKEEVvqtskSEEVAPKAANAST-------------VYRPpyyrkphkyhesshilqeeFANAGDASG 79 
EEZ98800              2 SALRLNKNLLkRCKKFKcf--sTAVLQEDEYTATP-------------QYPP-------------------I---LDMSP 44 
Q9VXP3                8 RHLRT-------TYKRCls--gQSQLQLNSTDAEP-------------AYPE-------------------I---QDLSF 43  fruit fly
WGS:AANI:GJ18480-PA   8 EQLRARLNAAcRRYLAIkaepkAVTVAESEYSAEP-------------EYPA-------------------I---RDMSF 52 
Q29CP7                8 NQLRA-------SYIRFva--qATSATSNEYSCQP-------------EYPP-------------------I---RDLTH 43  Drosophi...
XP_322027             4 RNFRPNLWLLgRHGHRAla-srPLPSKEHEYTNSP-------------EYPP-------------------I---QDLSF 47  Anophele...
XP_023116621          1 MAAARCCRLA-LRRSRL-----SLHTAAEAAVAAPevtgavvaaapvaRYPP-------------------IVASLTAKS 55  domestic...
XP_004017055          1 MAAARSWRFV-FRGPGL-----SLHTAAEAAVTAPevtgsdvkaapvaRYPP-------------------IVASLTADS 55  sheep
O61818               84 AGVRVFDYYKTAEMVHSMPTIKEKIDFVSPYERPwtraektwrrdwhptLMatrkawGIPPTPAHFDTLDYYKYLTKTRV 163 Caenorha...
XP_004058926         56 KAARLRRIERWQATVHAAESVDEKLRILTKMQFM---------------KY------MVYPQTFALNADRWYQYFTKTVF 114
XP_002639732         80 AGVRLFDYYKTAEMVNAMPTIKEKIDLVSPYERPwtraertwrrdwhptLMatrkawGIPPTPAHFDTLDYYKYITKTRV 159
EEZ98800             45 EKVRERRKEEEYEGIKAVKTVEEKQ---IKLNMP---------------KYygfksyMLYEDYIPYNSLPLIQHVTRTHL 106
Q9VXP3               44 KARKQKDAANWHEEIRQVPTVEEKM---IKINMP---------------RYygfkvvDFNDSKIPYNALPLTQHYTRTVL 105 fruit fly
WGS:AANI:GJ18480-PA  53 KGRKLQSAAEWHEEIRQVPTVEEKM---IKINMP---------------RYygykvvDLNDTKVPFNALPLTQHYTRTVL 114
Q29CP7               44 KALKRREANDWHEEIRKVPTVEEKI---IKVNMP---------------RYygykvvDFNDNKIPYNALPVTQHYTRTVL 105 Drosophi...
XP_322027            48 PAKKKRERESWHQKIAKLSSVEEKL---FEINMP---------------KYygykmnMLTDEKFPYNIKPFMQYATRTCF 109 Anophele...
XP_023116621         56 KAARQRRVERWQATVHAAESVDEKLRILTKMQFM---------------KY------VVYPQTFALNADRWYQGFTKTVF 114 domestic...
XP_004017055         56 KAARQRRVERWHATVHAANSVDEKLRILTKMQFM---------------KY------VVYPQTFALNADRWYQNFTKTVF 114 sheep
O61818              164 en--------------------esLDDFYHGLRPPTAD-LQTS-----FQNtLKSMEFGDGINFSDEDTQKLFGSLIDDA 217 Caenorha...
XP_004058926        115 lsglppppa------epepepepePALDLAALRAVACDcLLQE-----HFY-LRRRRRVHRYEESEVISLPFLDQLVSTL 182
XP_002639732        160 en--------------------ksLDDFYHGLRPPTAE-LQQS-----FQNtLKSMEFGDGITFSEEDTQKLFGCLIDDA 213
EEZ98800            107 iknenlpnf----------yndldvtsaLNDVKSDIEEaILIElarhrQTLdLQG----DKVEADNRLGFALSKQINRII 172
Q9VXP3              106 edlpsetdkkaqakdseqeqeqpsVDGLFKAARGDVIDaLEFAhdyykHLEkQHNSAESNPVERERILTQIIVEQLNRAL 185 fruit fly
WGS:AANI:GJ18480-PA 115 eelppkqa--------epgeekvdLDATVKVARNDIIEaLEFAhdcykHQLtLLD-TPPDAVTREQQLTQIIVEQINRSA 185
Q29CP7              106 kelpllsad-------etetsefsSVAFLKTARDDIIDaLELAhdfynHQAtLPDVAPSDSVNRERQLTQIIVEQLNRAL 178 Drosophi...
XP_322027           110 qtglpqyy----------dplkeeaaKILESIQTELEDtIALElsnysH---VKRDETVSPVEKEETVVRSLLVQLNRTI 176 Anophele...
XP_023116621        115 lsglpppppg-----epaepaepsPTLDLEALRAAACDcLLQE-----HFY-LRRKRRAPLYQDREAIASPFLDQLVAAL 183 domestic...
XP_004017055        115 lsglpplpaq--------pdrepaqvlDLAALRTAACDcLLQE-----HFF-LRRKKRAPIYQERYTVASPFLDQLVASL 180 sheep
O61818              218 MGGIAHNVSRLADHR-VAYDVESEAFWVRSGFMFLydee-eigtRDVKRRLNNFPKFIGDDrrklgelafvhrdKLAAQV 295 Caenorha...
XP_004058926        183 VGLLSPHNPALAAAA-LDYRCPVHFYWVRGEEIIP---------RGHRRGRIDDLRYQIDD-------------KPNNQI 239
XP_002639732        214 MGAIAHNVSRLADHR-VAYDVESEAFWVRSGFMFLydepvigsnKDHKRRLNNFPKFIGDDrrklgelafvhrdKLAAQI 292
EEZ98800            173 TTRMSRHLPHLKGAQ-VDLNSRIKSFWLAGGMSPP---------ENIKRYR-RGCSWQKDKeneptnrvmnyigSANVSL 241
Q9VXP3              186 LQSLSEEYKHLDELD-VDYNPRHEAFWAVGGVDPP---------KNVQKSK-KGREWQKDManesvdrmvqytgAPYLAL 254 fruit fly
WGS:AANI:GJ18480-PA 186 LQVLSAEYPHLNEVE-IDYNPRHEAFWAVGGVDPP---------KNVVKSK-KGRDWQKADaydsvdrlvqytgEPYLAL 254
Q29CP7              179 LQILSADYPHLNDVE-VDYNPRHEAFWAVGGVDPP---------KNVVKSK-KGRDWQKDDasesvdrlvqytgAPYLSL 247 Drosophi...
XP_322027           177 ANALAPKFNHLNEIE-TDVDPRHEAFWFLGGIYPP---------NLVRKIK-EGVEWQKQYandpydrniqyvgKPYMAL 245 Anophele...
XP_023116621        184 VGLLSAHNPALATAA-LDCKRPVHFYWLRGEEIIP---------SGHRKGRVDALRYQIND-------------KPHNQI 240 domestic...
XP_004017055        181 TGLLSAYN-PVLAAAaLDCNRPVHFYWLRGEEIIP---------GGHRKGRVDAVRYQIND-------------KPHNQI 237 sheep
O61818              296 RSKEPSA-PLHSFDSedaklpIFDTNYnfeetlfspKVYNLWPDQEPLWQCPGYHADS-------GESHTYGILGVKSLR 367 Caenorha...
XP_004058926        240 RISKQLA-EFVPLDY------SVPIEI---------PTIKCKPDKLPLFKRQYENHIFvgs--ktADPCCYGHTQFHLLP 301
XP_002639732        293 RSREPPA-LLHSLDSddaklpVFEKDFnieetlyspKVFNLWPDQQPLWQCPGYHADS-------GETHSYGLLSVKSLR 364
EEZ98800            242 RTDLPLKhIISSSDAesp-----dlSV---------PFFEFDPRTVGTVANQHRHIANvpg-fwpGDSREFGFLSYH--- 303
Q9VXP3              255 RHRKQLT-PWK-TEAese-nlELSKQL---------PRFKHDPRTLG-YSTKHQHATNvpgywpkGNENNFGLLSFQ--- 318 fruit fly
WGS:AANI:GJ18480-PA 255 RHRHQLP-TWK-TPEese-nlTLANQL---------PRYKHDARTLG-YSTKYQHAINvpgywpsVNAPNFGMLSFQ--- 318
Q29CP7              248 RHRQQLC-PWM-TDGeskmmdPHARHL---------PRFNHDARTLG-YRTSYQHAVNvpgywpsANGANFGLLSFQ--- 312 Drosophi...
XP_322027           246 RHKLLLE-PLLPKDLesfdvkQDGAEI---------PDYRYDPLALG-YIADFRHATTvpg-fwpGEQHEFGLLSFQ--- 310 Anophele...
XP_023116621        241 RMSKQLP-EFVPLDY------SVPVEI---------PVMNCKPDKLPLFKRQYENTIFigs--ktADPYCYGHTQFHLLP 302 domestic...
XP_004017055        238 RISRQLP-EFVPLDY------SVPVEI---------PVKNCKPDKLPLFKRQYENAIFigt--rtADPLCYGHTQFHLLP 299 sheep
O61818              368 PLRKRiahwmgweNENELESseeAKQMLDDGARSQAIISMFTTLCAQAHTHGFTQYTDITRSFTSQLVLSDGINFWFAIG 447 Caenorha...
XP_004058926        302 DKLRR--------ERLLRQN---CADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCY 370
XP_002639732        365 PLRERvahwmgweSQAELEEspeAKQMIDDGARSQAVISMFTTLCAQAHTHGFTQYTDVTRPFTSQMILSDGLNFYFAVG 444
EEZ98800            304 ---KR--------GHLISRHy-gDANELKEAVDRQGILASFGWLNAQANFQGFTTFNDVTYPFVTQTVVTNGQVWSFYVY 371
Q9VXP3              319 ---SR--------AHLQIRPksfGEQDQLEALHSLAIKSSYAWLLAQANYNGFNTYNELTYPMNTQTVITNGREWSFYEY 387 fruit fly
WGS:AANI:GJ18480-PA 319 ---SR--------AHLQLRPqacGERDQLEALHALGIQSSYAWLLAQANYNGFNTYNELTYPLNTQTVITNGREWSFYEY 387
Q29CP7              313 ---SR--------ASLQMRHkayGDRDLQEALHALAIKSSYSWLLAQANYNGFNTYNDLTYPMNTQTVITNGREWSFYEY 381 Drosophi...
XP_322027           311 ---RR--------SHALNRHkycAVDDLSEAIDAQGILSSFAWLLGQACYQGFSVFNDVTYPLTTQTVITDGKYWSFYAY 379 Anophele...
XP_023116621        303 DKLKR--------ERLLKQN---CADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCY 371 domestic...
XP_004017055        300 DKLKR--------ERLLKQN---CADQIEVIFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCY 368 sheep
O61818              448 QLNTIAINVECDGfVNPRTNYIRIDGPYRLFDYCdKNGQYLsvqeeidaenkvqrkiapGLNEKVLERVTQMLM 521 Caenorhabditis...
XP_004058926        371 QLNTLALTTQADQ-NNPRKNICWGTQSKPLYETI-EDNDVK------------------GFNDDVLLQIVHFLL 424
XP_002639732        445 QLNTLAINVDCEGfVNPRTNFIQIDGPHRLFEIVdEDGNYTssqeyvdaknnvnrrvdsGLNEKvlervtqmlm 518
EEZ98800            372 QLNTIVNHSKFFT-ENAKRNVCWGTPEVKLFEGV-ENDKLV------------------GFNDEVLKMLLKFYA 425
Q9VXP3              388 QLNTLLLHGTNVA-ENPRVNFCRGTKPLPLYAEIsASGKCV------------------DFNDNALRHLLNFYA 442 fruit fly
WGS:AANI:GJ18480-PA 388 QLNTLLVHGPHVD-SNARVNFCRGTAPQPLYAEIsPEGKCV------------------DFNDGTLRQLLTLYI 442
Q29CP7              382 QLNTLLLHSNQVN-ENPRVNFCRGTPPLPLYAEIsEKGKCV------------------DFNDATLKQLLRVYM 436 Drosophila pse...
XP_322027           380 QLNTTLLHSDQVD-ANSRYNLCWGTDAMQLYESIdENGKIN------------------GLNKEVLQQIIMFYI 434 Anopheles gamb...
XP_023116621        372 QLNTLALTTQADQ-NNPRKNICWGTQSKPLYETI-EDNNVK------------------GFNDDVLLQIVHFLL 425 domestic cat
XP_004017055        369 QLNTLALTAQADQ-NNPRKNICWGTQSKPLYETI-EDNDVK------------------GFNDDVLLQLVHFLL 422 sheep
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