Conserved Protein Domain Family
Lipid_desat

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pfam10520: Lipid_desat 
Lipid desaturase domain
This entry represents a family of lipid desaturase domains. The TMEM189 protein is a plasmanylethanolamine desaturase enzyme. The domain is also found on fatty acid saturase FAD4 in Arabidopsis.
Statistics
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PSSM-Id: 463132
Aligned: 47 rows
Threshold Bit Score: 191.68
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q38C19        92 MVLSDFISGVAHWSFDTWGTPETFLFGN-FIRSFREHHVNQMAMTKHDFIETNADT--------TLPLIPVLliqlyflg 162 Trypanosoma brucei
Q89SH1        77 YFLADFFSGLVHWAVDTWLDEGG--LGRgIA-MTREHHTHPSHVLLYEFLDQASLGaapsavvvGISAAITAl------- 146 Bradyrhizobium ...
EFH45841     137 YILADLGSGVYHWAIDNYGDESTPVVGS-QIEAFQGHHKWPWTITRRQFAN-NLHAlaqvitftVLPLDLAF-------- 206
EFH64296     102 YVLADLGSGVYHWAIDNYGDKSTPLVGA-QLEASQGHHKWPWTITKRQFAN-NSHTiaraitftVLPLNLVI-------- 171
XP_009109154 115 YILADLGSGLYHWAIDNYGDESTPLVGT-QIEAARGHHKWPWIITIRQFAN-NSHAlargitftVLPLVLAC-------- 184
O81006       105 YILADLGSGVYHWATDNYGDESTPLVGI-HIEDSQDHHKCPWTITKRQFAN-NLHFmargttliVLPLDLAF-------- 174 thale cress
1_pfamImport   1 YVLSDLASGIYHWGIDNYGSAKTLVFGN-QIDAFQHHHKQSWIITKSQFAK-NHRIlawgvtftVLPIDLLC-------- 70 
CBJ27287      40 YTIADLVSGVFHWSVDNYGDGSTPVFGA-VIEAFQGHHGSPWTITYRPFEN-NVHKia----yaVLPLLALL-------- 105
EED94891       3 WVLADFGSGVFHWSVDNYGNGRTPVMGS-IIAAFQGHHSAPWTITYRGFCN-NVWKlcipfglpTVAAISYI-------- 72 
EEC43146       1 WVIADFGSGVLHWATDNYGNGKTPVMGG-IIAAFQGHHSAPWTIAQRGFCN-NVYKlcipfgivPMLAINAI-------- 70 
Q38C19       163 cnsknnstfryNIDNDNAGFHVFFLTFALFIGMTNELHKWAHLP--APHPFARLLMSCRIVLTRKSHRRHHRGSYD-RSY 239 Trypanosoma brucei
Q89SH1       147 ----------fPVSALTYALMIVWFVIATCMLFGMSFHNLAHWR--VRPPLLRMAQRLHLVCSPEHHLRHHRD-HT-VRY 212 Bradyrhizobium ...
EFH45841     207 ---------------NDPVFHGFVCTFAFCIMFSQQFHAWAHGtksKLPPLVVALQDMGLLVSRRQHAEHHRAPYN-NNY 270
EFH64296     172 ---------------NNPLFHSFVSIFAFCILLSQQFHAWAHGttsKLPPLVVALQDMGLLVSRKHHLGHHQAPYN-SNY 235
XP_009109154 185 ---------------NDPVVHGFVSMFAFCILFCQQCHAWAHErksKLPPLVVAFQDMGLLLSRRQHVNHHRHHRTyMSY 249
O81006       175 ---------------DDHVVHGFVSMFAFCVLFCQLFHAWAHGtksKLPPLVVGLQDIGLLVSRIHHMNHHRAPYN-NNY 238 thale cress
1_pfamImport  71 ---------------KDPTILAFIGAFFGCIMFSQQFHSWAHGtknKLPKIVLALQDVGILVSRSQHAAHHQLPYN-NNY 134
CBJ27287     106 -----------RLVNPGPAGVALGVAFLVGSLMSNEFHRFAHMT--SPPPIVRALQKFGVTVSRKEHGRHHSSPFE-EKY 171
EED94891      73 ------------AGPENSMVTLFFTFFCAIEIMSQELHKWSHMtkkETPAFVNTLQALGVTIARVPHAQHHLAPYD-GNY 139
EEC43146      71 ---------------APPDVVFFMATFCVFEIMSQEFHKWSHQlksETPGWVNWLQDSGLTIARKPHALHHLAPFE-GNY 134
Q38C19       240 CITTGWLNAPLDRVDFWRKAEAVVTALTGAVPRAN 274 Trypanosoma brucei
Q89SH1       213 CVINGWANYPCDSLRLWSRLERLVTATTGRTPRAD 247 Bradyrhizobium japonicum
EFH45841     271 CIVSGAWNSVLDESKVFEALEMVFYFQLGVRPRSW 305
EFH64296     236 CVVSGAWNKVLDESKFFEALEMALYFQFGVRPRSW 270
XP_009109154 250 CIVSGVWNNVLDDNKIFEALEKVLYVQFGVKPRSW 284
O81006       239 CVVSGVWNKVLDESNVFKAMEMVLYIQLGVRPRSW 273 thale cress
1_pfamImport 135 CLVSGLWNNFLDGYKVFELLERILFFIFGVRPRSW 169
CBJ27287     172 CIVTGVCNGPLDHFRVFRFMERVVYELNGVEPIAW 206
EED94891     140 CIVSGLCNETLDKSGFFRWMEHKVYELNGVESNAW 174
EEC43146     135 CIISGICNPVLDQSGFFRRLERVVYSLNGIESNAW 169
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