4GA5


Conserved Protein Domain Family
AMP_phos
?
TIGR03327: AMP_phos 
Click on image for an interactive view with Cn3D
AMP phosphorylase
This enzyme family is found, so far, strictly in the Archaea, and only in those with a type III Rubisco enzyme. Most of the members previously were annotated as thymidine phosphorylase, or DeoA. The AMP metabolized by this enzyme may be produced by ADP-dependent sugar kinases.
Links
?
Statistics
?
PSSM-Id: 274520
Aligned: 10 rows
Threshold Bit Score: 761.151
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
4GA5_B         2 KAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEa--GKKAVYGSVALS-NLVGKGEVGISRDVLDLHnFSEGETVS 78  Thermococcus ko...
WP_011032041   3 QLKLEHYNIKIGQHKVLLNIVDAKELGVNPGDRVRIR---GHQSLSAIVDTTdDMVPPGTLGVFTEVYEHF-EDWDKPVE 78  Methanosarcina ...
WP_011498424   2 QLKVQPIDVKVGKYKVILNTIDAKELGVHEGDRVRIK---NHVTLTAIVDFTeDMISPGMIGLYHEVKEALsKEWTETVE 78  Methanococcoide...
WP_010885672   2 RAKVKILKIKTGSFNVFISPRDAEEWKLHPNDLVKIEs--GKRSIYASVAIg-DFIEDGEVGLSQDILSSYqFSEGEVVS 78  Pyrococcus hori...
WP_011449225   2 RLTVRLVDIAA--RGILLHHNDAKSLGVLAGDRIVISspvTGKATVDYVETTgTLIDQGRIGVYHHTNEQLtLTENEVVE 79  Methanospirillu...
WP_011249307   2 KAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEa--GKKAVYGSVALS-NLVGKGEVGISRDVLDLHnFSEGETVS 78  Thermococcus ko...
WP_010878838   2 IFKAVRVPFKSGRFAVILNEEDASELGVREGDRVRVRy--GKAGVVATVQITrEIVEKGFVGLTDLASMELgISDGAEVD 79  Archaeoglobus f...
WP_010870172   3 FLKVRVLDIDL-ENLVLINSEDLKSSQYFPQDRVVVEf--KGKEVIGILHSStTLINRGEIGLPQKVVKELgVKEGDIVT 79  Methanocaldococ...
WP_011323686   2 ELTVEPIDIGTERPVVLLNCADAETLGVHSLDRVEIDw--DGTTEVGIVKVTdELVAAGRIGASHGFPE---ITDGTVVA 76  Natronomonas ph...
WP_011170271   3 FLNAKFIDLDLGENAVIVNEDDLKGTSYYPQDRVLIEs--HAGSVIGNIYSTkTMVQKGEVGMLVSELAEIsISEGEEVK 80  Methanococcus m...

4GA5_B        79 VIPAGTPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETGDMLDIDRK 158 Thermococcus ko...
WP_011032041  79 VVPSFRSKSAAVIKKMLDKKPVVQDEIKMLVSDIVDENLSDVELSAFITASYIHGMTDDEVEWLTRAMIDTGDTIEFDTH 158 Methanosarcina ...
WP_011498424  79 VFPAEKPKSTYIIRKTMDGQKLTKEEIDILVKDIVEENLAEIEIAAFLTATYINDMTDDETEWLTRAMIDSGDKLEFDTH 158 Methanococcoide...
WP_010885672  79 ITPSGTPESVKYIKKKMKGEKLRKVEIETIIRDIVDRKLRNTEISAFITAIEINGLSMDEIAALTIAMAETGDMLDIDRK 158 Pyrococcus hori...
WP_011449225  80 VRVADRPVSLDYIKKKMEGEKLTREDIRAIVADIVQDTLSPSEITAFVVSSYINQLDMDEIESLTRAMVETGDQLSFHAG 159 Methanospirillu...
WP_011249307  79 VIPAGTPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETGDMLDIDRK 158 Thermococcus ko...
WP_010878838  80 VFPSPKPKSVELIKKKTRGEKLSQDEIRRIVEDITNNALSEVELTAFVISSMLRGMDFDEIEWLTRSMIETGERIEFDRG 159 Archaeoglobus f...
WP_010870172  80 IKHAEKPKSLPYIRKKMDGNKLKKEEIFEIIDEMVDGKLTNIEISAFVTSLYINGMDMDEIEAMTIRMAETGEMVNWEGH 159 Methanocaldococ...
WP_011323686  77 VTPAGQPESVESIRRKLDGRELDSDELGAIVADIEADRLSDLELSAYVCASHANGLSLEETKQLTERMAEVGKQLSWEQP 156 Natronomonas ph...
WP_011170271  81 LRHAEKPESIPFIKKKMDGQVLNPHEIRTIIDEIVSKKLSNIELSAFVSSTYINGMNMDEIGEMTKRIAETGDMISWEKN 160 Methanococcus m...

4GA5_B       159 PIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALN 238 Thermococcus ko...
WP_011032041 159 PIMDKHSIGGVPGNKISLLIVPIVAANGLLIPKTSSRAITGAGGTADLMEVLSPVEFSSQEVKEITEKVGGALVWGGATN 238 Methanosarcina ...
WP_011498424 159 PIMDKHSIGGVPGNKISLLIVPIVAANGLLIPKTSSRAITGAGGTADLMEILAPVEFDAAEIKRMTEEVGGVLVWGGATN 238 Methanococcoide...
WP_010885672 159 PIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVLTNVKLSLDEIKRIVEKIGACLVWGGALN 238 Pyrococcus hori...
WP_011449225 160 PIVDKHSIGGVPGNKISLIVVPIIAASGLLIPKTSSRAITGAGGTADLMEVLAPVEFSASEVQEMTIKTGGVIVWGGATN 239 Methanospirillu...
WP_011249307 159 PIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALN 238 Thermococcus ko...
WP_010878838 160 TVVDKHSIGGVPGNKISLLIVPTVAAAGLLIPKTASRAITSASGTADTMEVLANVNLSVDEIKEITERVGGVIAWGGATN 239 Archaeoglobus f...
WP_010870172 160 -IFDVHSIGGVPGNKYALLVVPIVASAGLKIPKTSSRAITSAAGTADVVEVLTRVDLTIEEIKRVVKETNGCMVWGGALD 238 Methanocaldococ...
WP_011323686 157 VVADKHSIGGVAGNRVTPVVVAIVAAAGLTIPKTSSRAVTSPAGTADTMEVFCPVEFSREEIRDIVTETGGCLVWGGAVD 236 Natronomonas ph...
WP_011170271 161 LVVDIHSIGGVPGNKYALLSIPILAAAGITIPKTSSRAITSPAGTADVMEVLTNVELKEDEIKRIVKTTNGCLVWGGGVN 240 Methanococcus m...

4GA5_B       239 LAPADDITIKAERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAIT 318 Thermococcus ko...
WP_011032041 239 IAPADDKLIKIEYPLSIDPYYQMLASIMAKKGAIGADNVVMDIPVGPGTKVPTVQEGQKLARDLINLGHRLGMNVECAIT 318 Methanosarcina ...
WP_011498424 239 IAPADDKLIKVEYPLSIDPHCQMLASIMAKKGAIGADHVVMDIPTGPGTKIKNVQEGRKLARDLINLGDRLGMDVDCALT 318 Methanococcoide...
WP_010885672 239 LAPADDLTIHVERRLSLDPRGLMLASIMSKKYAIGSQYILIDIPTGKGAKVETMDEARTLAKDFIELGKKLGQYVEVAIT 318 Pyrococcus hori...
WP_011449225 240 IAPADDKIIIQEYPFKIDQIGQMIASVMAKKFAVGADVVAIDIPVGKYCKVHTIEEGKKLARQFIDLGERLNMRVECALT 319 Methanospirillu...
WP_011249307 239 LAPADDITIKAERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAIT 318 Thermococcus ko...
WP_010878838 240 IAPADDKIIRVEHPLSIDPRPQLLASVMAKKGSVGAKHVVIDIPVGEGAKIEKVEVGRSLANDFIELGRRLGLNVMAAIT 319 Archaeoglobus f...
WP_010870172 239 LAPADDITINVERPLGIDPEPLLLSSVMAKKLAMGVNKLLIDIPTGYGAKVKSIKEASSLARKFIELSDRLRIVTECAIT 318 Methanocaldococ...
WP_011323686 237 LSPVDDKVIRAQRPLSLDPPGQVIASVLSKKQSAGSSHIVVDIPYGAGAKVTSLSEARDLADDFRRVGDHLGLTIECALT 316 Natronomonas ph...
WP_011170271 241 LAPADDIIINVERPVSIDPQPQLLASVMAKKIATGIKYSVIDIPVGKGVKIKNEAEGAKLARKFIELGELLNIKVECVLT 320 Methanococcus m...

4GA5_B       319 YGGQPIGHTVGPALEAREALSALMTGKG-PGSLIEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQ 397 Thermococcus ko...
WP_011032041 319 YGSSPIGRRVGPSLEVKEAMKVLESMEG-PNSLIEKSAALAGILLEMGGAAPRDQGKELALETLRSGKALEKMKQIIEAQ 397 Methanosarcina ...
WP_011498424 319 YGASPVGRTIGPALEVIEALKVLESFEG-PNSLIEKSASLAGMLLEMGNVAGKDKGYDLAIETLKNGKALTKFKEIIKIQ 397 Methanococcoide...
WP_010885672 319 YGGQPIGYAIGPALEAKEALETLMTGKG-PGSLVEKATGLAGILLEMGGVAPKGMGKKVAKEILESGKAYEKMKEIIEEQ 397 Pyrococcus hori...
WP_011449225 320 YGDAPVGRAIGPKLEIKEALSVLEGSDS-PRSLIQKSCVIAGIALELAGKANRGEGANLALEILRSGKALKKFLDIIAVQ 398 Methanospirillu...
WP_011249307 319 YGGQPIGHTVGPALEAREALSALMTGKG-PGSLIEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQ 397 Thermococcus ko...
WP_010878838 320 YGGQPVGRAIGPALEAREALKTMEDRRG-PSSLVEKSLGIAGILFEMTGIAT--NGYQHARKIFESGKTLEKFREIVAAQ 396 Archaeoglobus f...
WP_010870172 319 YGGQPIGRAIGPALEAKEALLALEDYTQaPTSLVEKSISLAGILLEMGGVAPTGEGKELAEDLLARGKAHDKFMEIIVAQ 398 Methanocaldococ...
WP_011323686 317 RGSDPIGHGIGPVLEARDVLAVLEG-EG-PEPLRIKSLRLADIIFDMAREAGMPVDDRSAADILDSGAALSKFRDIVAVQ 394 Natronomonas ph...
WP_011170271 321 YGGQPLGRAIGPALEAKEAIEALQDPKNaPKSLIEKALSLAGILLELGGAAQIGEGQNLAWEILESGRALEKFNQIIIEQ 400 Methanococcus m...

4GA5_B       398 GGDPnIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEARL 477 Thermococcus ko...
WP_011032041 398 GGDPnIKSDDIQTGQYTADIFASTDGYVMEFDNKWIIEIARLAGAPNDKGAGVAIHKKRGEQVKKGDPILTIYAEKEIKL 477 Methanosarcina ...
WP_011498424 398 GGNPdVTHKDISVGEFTEDIIAPNNGYILEMDNKRLVQIARLAGAPNDKGAGILLHRKQGEPLKEGDPVMTIYAEKKSKL 477 Methanococcoide...
WP_010885672 398 GGDPnIKPEDIPIGDKTYTIHAQTGGYVTGIDNRAITAIAREAGAPEDKGAGVRLHVKVGEKVKEGDPLITIHAESESRL 477 Pyrococcus hori...
WP_011449225 399 GGTPdVSSEKITVGEHFYTVRADSTGYVIDLNNHSLITIARTAGAPADHGAGLYLHAKHGTSLSKGDPIFTIYADRKWRL 478 Methanospirillu...
WP_011249307 398 GGDPnIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEARL 477 Thermococcus ko...
WP_010878838 397 GGDEsVKAEDVAVGDKTYTLTSQVEGAVVSVNNKSIVKIARTAGAPKDKGAGVYVHKKRGEVVKVGDPLLTIYAEKEWKL 476 Archaeoglobus f...
WP_010870172 399 GGKE-VSSDEIEVGKYKADIHSPIDGYVTRISNAGITKIAKEAGAPNDKKAGIYLNVKVGNKVEKGDVLYTIYSDSEERL 477 Methanocaldococ...
WP_011323686 395 GGDPdVSRDDLQPGDRTETVTADTDGLVVDVDNQAVSQLARRAGAPNDHGAGVVIHRRTGDKAVAGDVLYTIHAESSDRL 474 Natronomonas ph...
WP_011170271 401 GGTP-KKPEEIELGDYIEEIIAPIDGYVTDINNTGITNVVKEAGAPRDKKAGLLLNSKIGNKVKKGDVLYTIYSGSEERL 479 Methanococcus m...

4GA5_B       478 DQAIVLARRTEPIRIEG 494 Thermococcus kodakarensis KOD1
WP_011032041 478 DNALATAQRTNPIIVEG 494 Methanosarcina mazei
WP_011498424 478 ENAVKSAKERPPFIVEG 494 Methanococcoides burtonii
WP_010885672 478 EKAIVLARRLEPIKIEG 494 Pyrococcus horikoshii
WP_011449225 479 EKAIEEARRLRPVMVEG 495 Methanospirillum hungatei
WP_011249307 478 DQAIVLARRTEPIRIEG 494 Thermococcus kodakarensis
WP_010878838 477 DNAIEVANTERPIVVSG 493 Archaeoglobus fulgidus
WP_010870172 478 KSAIKLARILYPIKVEG 494 Methanocaldococcus jannaschii
WP_011323686 475 EAAREYAAGDEIVRVGG 491 Natronomonas pharaonis
WP_011170271 480 VSAVNLARRVYPVKVEG 496 Methanococcus maripaludis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap