ETN67624      217 HIPSCLKNLYST--HEDVEVGRCVQKFAG--IP-CTWNYEMQSILHHN-SSGYRAFS----GTL-----KSKEVHNAITL 281 
PDM68310      221 QRHVCNN-MLAG--SDEQGMEMCIHAATN--VS-CRTEHQGREYRFWRvSGTESPHEeiqrWSM-----ETPSLNSSLSV 289 
XP_011435911  243 GLDWCLTNSPEA--NPSEIFGQCLYHSAK--LP-CSKHGGDKEYRHYKvEdf-------dyDDDiatlrEDGRFNSSFSV 310 
XP_001601123  232 NLDWCVKTTFSS--SDDVNIGRCILHSAS--LP-CTHKAQEQIYFSTKlNVtf------dyQNDfkklcADEDFQKSITI 300 
EGI68285      394 NLDWCVKNAYSD--SDDVNFGRCILHSTS--MP-CTNHIEGRNLTFIQlKSif------nfEKDfvqltEQNEFQNSVSI 462 
XP_001946198  231 NVDWCVRNAFST--SDDDNFGRCVLHSVN--LP-CQTSIQGQTISSYRlWEAKDLINllnqPQ------QQDSFNRALTV 299 
Q29IB5        171 NLDRCVRIGITG--DHSVNIGRCVKYASH--VPgCQESFQGMRQYSYAlN--TPGRQrrdfSELa----KEEAFRNASTV 240  Drosophila ps...
ETN62052      261 NLDWCVRNALGD--DHSHNIGKCVKYSAKl-DG-CHDRWQGIAVSSYRlSsf-------kiYRDfhliaKEPAFNGASTV 329 
XP_318249     241 NLDWCVRNAVSN--YHSVNIGKCVKYSAKi-KT-CHQSWQGVDITSYNiAgy-------kiYRDfhliaEQEAFNKAAMV 309  Anopheles gam...
XP_002122339  284 QLDACSEDGSQAslSPDKWLGRCIKRATSgaVE-CVDEEEAIFYHTFNmE---NSNLnfevE-------TTPEFEEAVTV 352  vase tunicate

ETN67624      282 HPIKQPAFMYRLHAYMLGLSAQELRQHSLLLHRDIAMATS-LLQL---PQinknlapgvpifpqdennidylgdHNVLGA 357 
PDM68310      290 GSILSTADASALHDHFIRVEVDKVEAEILKMEEEIEGMEE-DLPDg---------------------------pSWPIGT 341 
XP_011435911  311 YPMPDDLSLFKVHRYFCQLELNLTRQEINKAKESIINLSY-YTVDgidSL------------------------SWPIGT 365 
XP_001601123  301 YPIYDHLMIYNINTHFAEMELLKVEKEIDSLRKQIVKTTS-FTPKnqqDL------------------------SWPIGN 355 
EGI68285      463 YPVYDYKLIYKFNMYFAAINSIKVHKQINDIRKIISATAH-LGPPnqrNI------------------------SWPIGN 517 
XP_001946198  300 YPMPNAETMYKTHLAFCKMNLEKSNMEIDALRRSIVAESS-LEPPsfrKV------------------------SWPVGS 354 
Q29IB5        241 YPVPTPEDFYRLHAYYSKQHLETVQERGYALEQKSYRIANgSISNkilEI------------------------RWPLGV 296  Drosophila ps...
ETN62052      330 FPVTVADDFYLLHAYFSRVHLETNNERKRQLQEEALQIAG-G-ALpndVLe----------------------vRWPLGV 385 
XP_318249     310 YPITSMDDFYLLHAYYSRVHLKQNTIVKRLLQNDAMQLSN--RTLsndILe----------------------vRWPLGV 365  Anopheles gam...
XP_002122339  353 SGVNSPQMMFQLHKKYSQLEIDKAYKEIGEIQDEIKSLVP-KLPEgerEL------------------------SWPIGI 407  vase tunicate

ETN67624      358 TPDLNrhrPRTLDELIQWDFIA-KSLYSSQHPN--PKRRMESSIKEGLSDVIREIMEHINNFSRQRGRMIEFRELLYGYM 434 
PDM68310      342 KPFAH---APNRYQVPVWEFFTaTEIFKNEPNQ--NVRPITGSDKEDIDEIIESAKRKAEEEEGDR--RVEFVRVSGGYR 414 
XP_011435911  366 PEATR---PKKRFDVIRWNYFTeSHIFFEDDFT--NMSPLNGVDKQDVLEVLQTAFKRANRLYDNK---FSKFQLINGYR 437 
XP_001601123  356 QPGSN---AMNRFDILRWTYFNmTHVFLDDDFG--TVKELNDYQKEDVNNVVNVTVKRVVDNYNKQ---LKFNKLLNGYW 427 
EGI68285      518 QPGNR---PLGRFDVLRWSYFNmSHVFFETDFI--NIQELKGDTKADIDNVINTAVNNIISKYDNK---LSFVRLLNGYL 589 
XP_001946198  355 QSGST---PSTRFDVLKWEHFTeTHLYLDSRIS--NIRPLNEAENADIHNVLNTSIEYLESKYSNN---MKFDRLVNGYK 426 
Q29IB5        297 PPPSA---PETRHDILIWQMLNeTHSYLPNGNVehAVAPLTRIEALDFAKVLEIALQYAALKHPGL----SYHSLHTAYR 369  Drosophila ps...
ETN62052      386 PRTSP---PESRHDIIKWTTLNlTHIFMRNTEE--NVRRLSAVDEQDIRNVLNKTVTEATRNQPDA----EYRGLHSAYK 456 
XP_318249     366 PKSNP---TESRHDVVPWVTLNtTHSFMWQSEV--NVKRLSAIDEEDIRNVLNKTILHAIRTHPDA----EFRGIHTAYK 436  Anopheles gam...
XP_002122339  408 NPSFK---PTNRWDIIVWDYFTeDYTLTCP-GEv-PKCDLTGVDKLDIQNILQIALDRLNEKYNPQGLILEKRKLINGYR 482  vase tunicate

ETN67624      435 RVNSMYGQDLILDLLLVYK-KYRgkkmTVPVRRHLYIQRSFTEIRVReitaqimpsqasvnqaehvssvgitkqprdpat 513 
PDM68310      415 QFDAARGMDYMVDLVYRDVnNEE------TIERRIHLARIIERTTLV--------------------------------- 455 
XP_011435911  438 RFEPSRGMEYQLDLKLREKdTNS------DVLKRFHLLRPLNKPELVpmpy----------------------------- 482 
XP_001601123  428 KFDSSRGVDYILDLSFATDsGV-------EVNKRIEVCKPLGKVEILpvpy----------------------------- 471 
EGI68285      590 KFDASRGMDYILDLVFNEVaTSK------EIRKRIEICKPLGKVEIIpvpy----------------------------- 634 
XP_001946198  427 RFDPSRGLDYILDLTFKDIvGNR------LIQKRVEVSKLLGKVEMLsvpy----------------------------- 471 
Q29IB5        370 KFDATRGMDYQLHLNLQKGsGRR----RRLLLKSFEVVKPLGRVEVVpspy----------------------------- 416  Drosophila ps...
ETN62052      457 RFDAVRGMEYRLLLNFYDRkRKR------MRTRSFEVIKPISLIEIVpspy----------------------------- 501 
XP_318249     437 RFDTVRGMDYRLLLNFYDRkRRT------MVQKSFEVIKPISLIEIIpspy----------------------------- 481  Anopheles gam...
XP_002122339  483 RFDPQRGMEYILDLLLTVImENEnq--eIELSHRVNMLRPLSQVEIIpmpy----------------------------- 531  vase tunicate

ETN67624      514 sfdrishrvktlfnelerltdsigsnlkekeN-------KDRVVFILPLSGR--SETFKRFLRNFEEVALRQeDQRT-DL 583 
PDM68310      456 -------------------------------NtvpyvkeDADLTIVVPIAEEveVLPGRRLLARQARLCTSPtEENR-HT 503 
XP_011435911  483 ------------------------------------vteTSQVFLILPLFEKd-VADGLHFLGEFQRNAIQI-KDNSvLC 524 
XP_001601123  472 ------------------------------------vteNSRINMIIAVDAFk-KEECMKFLAHYADTCMDR-KDKVtLT 513 
EGI68285      635 ------------------------------------vteNTRINIIITIDLSk-KQDAVNFIEHYSQNCMEK-KCKTyLM 676 
XP_001946198  472 ------------------------------------vteNTRVHILLPVRTNe-REDAFRFLRQYKQVCIDK-KEKTmLM 513 
Q29IB5        417 ------------------------------------vteSTRIAILVPAFEHq-VPDALEFVAQYERLCMQN-QDNTfLL 458  Drosophila ps...
ETN62052      502 ------------------------------------vteSTRVAILLPVLEHq-VQETEQFLESYERTCMDS-QDNTfLM 543 
XP_318249     482 ------------------------------------vteSTRVALLLPVFESq-ILEAEQFMELYEKTCMES-QDNTfLM 523  Anopheles gam...
XP_002122339  532 ------------------------------------vteSAKVHIILPLTKQe-RVYFEAFMDKYAKVCLNN-DENVaLN 573  vase tunicate

ETN67624      584 LVALYVE--------APESSELITQLLNLRARYPGSR-----INYLPLT-----------------------GNFSRGVA 627 
PDM68310      504 RVVVAVSar----veHKSLIFIQNDLEELKKRCKRSS-----LEASLLSvss-----------------dnpSSLHAAEA 557 
XP_011435911  525 LYLIYKKdk----fsSDPFVNVKSTVASITSQPNSNNk----IMMKSVEmn--------------------lSSIKEMEF 576 
XP_001601123  514 VVLLYNPgyas-kgnEDIFHEIKKRALFLTEKYKKDQl---kVTWLSIRlptis-------------sfieiEPLLKIAI 576 
EGI68285      677 VVLLYNSdsps-kgkGDVYLDVKTYISMLNEKYKKDQs---kITWLSIRlpvnv-------------tsvdlDPMLKIAV 739 
XP_001946198  514 LVLLYDAnapgkgavDDVFKQLKDEATSLSNAHKKDGt---kVAWLSVKipntk-------------llalrDALLDFAI 577 
Q29IB5        459 LIFLYRLdsps-kgdEDPFKGLKTLALDLSSKYKTDGs---rIAWVSIRlpeqlseavrpedwllhasmygpKQLLSLVV 534  Drosophila ps...
ETN62052      544 LIFFYRAdtps-kgdEDVFLPLKNIALAVTEKHKQDGs---rVAWVSIRlppelsgkfdd-nhryyssmygqHGRLAFAA 618 
XP_318249     524 LIFFYRAetps-kgdQDVFLPLKNIALALTEKHKQDGs---rVAWVSIRlpidesitfnn-snryssslnvpQTLMNFVA 598  Anopheles gam...
XP_002122339  574 IVFVYDPetaqrihqDDIFAEQKQLLQSYEARYKKDGkegklIPWVSIKtev----------------------psQLKT 631  vase tunicate

ETN67624      628 LDRAIRSSycASDDIIFFIDVDMIFTVQSIDRIRLNVIRGRQIYLPIVFSEYDPQMMG----WQAEtqivmqgsmggyts 703 
PDM68310      558 LDEAIDHF--GPQSMFLLLSPYADIQKELLDRARINTIKKFQVFLPIPFIEYHPTISGmdlkDGEKpddestrqral--- 632 
XP_011435911  577 YDVIVSDF--SASTLVSMVTPGMELELDYINRIRMNTIAGVQIYFPISYWQYKPNLAYdqkpYP---------------- 638 
XP_001601123  577 ADLYVKKF--SSDNLILFADTRMELKSEYLNRVRMNTISQWQVFSPIPFVQYNPDIIYydasVKH--------------- 639 
EGI68285      740 TDLCAKKF--SSESLILLVETGTKLKIDYLNRVRMNTINRYQIFSPIPFIEYHPDIIYadevVTH--------------- 802 
XP_001946198  578 IDLAIRKF--PPDALMMLARPKMEIRQDYLNRVRMNTIMEWQIFSALPFSEYDPNLMTyprqA----------------- 638 
Q29IB5        535 ADLALPKL--GLESLVLLATPGMSFKADFLNRVRMNTIQGFQVYAPIGFQMYPCRWAQfckeCE---------------- 596  Drosophila ps...
ETN62052      619 VDLALRKI--GLESLVMLCSNAATFRSDFLNRVRMNTIQGFQVFSPIGFNMYPCEWTGlckpCE---------------- 680 
XP_318249     599 VDLALRKI--GLESLVIVCTNSASFRPDFLNRVRMNTIQGFQIFSPIGFMMYPCEWTGlcklCE---------------- 660  Anopheles gam...
XP_002122339  632 MDIVAKKY--PTESLFLLTSVAANMNTNFLNRCRMNAIPGWQVFFPIPFSQYNPQIIFq--nGQV--------------- 692  vase tunicate

ETN67624      704 lknfalpllpenfSLPYRITDENGYFRQFGYGLAGMYKADLQRpdlkgFSTDITGWGLEDV------------------- 764 
PDM68310      633 --gtlkdaappqrTKGLMVQKEHGRFDPLDFSVVCIYGSDYME-----VRPRLM--NGKRI------------------- 684 
XP_011435911  639 --------------DMVELTQKYGHFEPLSFFHCSFYVSDFQK-----ARRSLTAIEVKHF------------------- 680 
XP_001601123  640 --------------VDFDIIHNHGRYDDYNYDSVSFYTKDYMT-----VRKSIE----NQVplvrtdkdias-------m 689 
EGI68285      803 --------------DEVDVNSNYGKYDEQNYNNIAFYIKDYNA-----MRQTVE----ANIplvrsdkdiat-------l 852 
XP_001946198  639 ---------------TLDVNKYYGHFDPFDYDHLSFYAKDYVV-----ARKRAE----SLIpiirvdrdihhlvtestsh 694 
Q29IB5        597 ---------------ACDVAQSSGYFDRHNHDVIAFYSRDYVQ-----ARKLLHPQGLPIIrsdldidqlle-------p 649  Drosophila ps...
ETN62052      681 ---------------NCDVGQGIGYFDRHNYDVVSFYSNDYVA-----VRKELE----SRLpivrsdrdivnllgtnatg 736 
XP_318249     661 ---------------NCDVGQSSGYFDHDNYDVVSFYSNDYVL-----ARKKLE----ALLpivrndkdilnfi---sti 713  Anopheles gam...
XP_002122339  693 -------------PEQIDIKPSNGHFDLYSFDEVCFYNSDYMA-----SRTKMA------Atvsaedske---------- 738  vase tunicate

ETN67624      765 ----------VFIENVIAlnhrgnqrlvaiadgrwdplrmrtsgaslnpkpssstvtgpsstahiptippavngvEELII 834 
PDM68310      685 ----------DVGSAFLNm-------------------------------------------------------pPGVHI 699 
XP_011435911  681 ----------SLIDMFLKy--------------------------------------------------------QKLHI 694 
XP_001601123  690 lqlsqtisigSIFEMFVVf--------------------------------------------------------SNLNT 713 
EGI68285      853 lklskhspvtSLFEMYVSf--------------------------------------------------------SDMHV 876 
XP_001946198  695 slkvvnmtnpSVYSMFVAy--------------------------------------------------------SECHI 718 
Q29IB5        650 asqsrpegveSILDMFVAa-------------------------------------------------------qHSVHI 674  Drosophila ps...
ETN62052      737 pvpptggpltNIVQLFLQa-------------------------------------------------------nTDLHV 761 
XP_318249     714 sshysnptisNIADLFTQs-------------------------------------------------------nNKMHV 738  Anopheles gam...
XP_002122339  739 -slsdlvdtlEVYDIMIKy--------------------------------------------------------SQLHV 761  vase tunicate

ETN67624      835 FRAPDPSLV---------------HIFHPIQCD-------TNLEEAQYKMCLGTKANTLGSLRTL 877 
PDM68310      700 LRAIEPALR---------------LRYHRRECD-------PDLEEDDLLRCTQSRRENLAAKDQL 742 
XP_011435911  695 FRAAEPALK---------------NRWQNITCN--------DKSNLQGEHCLERRNQNLATRAQL 736 
XP_001601123  714 FRAVEPALK---------------LKYKEINCI-------GTRNNITLNTCLKQRNLQLGNRGQL 756 
EGI68285      877 FRAIEPTLK---------------IKYKDVNCD-------DVSNDNIYKNCLKLRNNHLGKRSQL 919 
XP_001946198  719 FRAVESGLR---------------LRHKQRHCElyegnivDHTSAALYGNCVRSRNRNAGSKGQL 768 
Q29IB5        675 LRGVEPNLR---------------FGHDVRNHLgr----gSTLPEQLPEQCGREQCIHLASRKQI 720  Drosophila pseudoobscura
ETN62052      762 LRAIEPNLRlgssirnflatdpngERFARLSCPe------PDDN---RQQCIR-----IASKKQI 812 
XP_318249     739 LRAIEPNLRfgrsvinslskdhsgKQISEFRCS----------KQKEKNKCIK-----VASKKQI 788  Anopheles gambiae str. PEST
XP_002122339  762 FRAVEPQLT---------------RRYVHRNCN-------KRNGQEIFDRCERSNAEGLASRTQL 804  vase tunicate