Conserved Protein Domain Family
MenH

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COG0596: MenH 
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Statistics
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PSSM-Id: 440361
Aligned: 945 rows
Threshold Bit Score: 34.9767
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_058235459   1 MAdtvtpla---------pfstgmLpv--sDG-H--EL-FY--------E----L----S-Gn----pEGI---PALYLH 41 
NP_601930      1 ------------------------------------------------------------mV------ESQ---HIIFIP 11 
WP_014452187   1 MKdef----------------------ltsDG-I--KI-EY--------EyncqKnddlD-G------ETV---AIVFLN 36 
WP_013317665   1 MSiek-----------------ciVt---yDSw---KI--Yv-------E----K----HiS------D-PaheTIIMVN 33 
WP_014797983   1 ------------------------mklklpDG-F--SI-YY--------EhhfiD------D------SKY---TLVFLN 29 
WP_024268931   1 MPdkv----------------------tirD--C--SI-GY--------El-------kN-G------EGV---TKLLLN 28 
WP_012662985   1 ------------------------Me------tL--KIdRF-------------Ef--lA-ApwpmdtDKQ---TLILVH 29 
WP_108603229   1 MSmqysl-------------qqytLq----lShT--AInYY--------Q----S----S-G------SGQ---TIVFVH 35 
WP_014804401   7 YPvpk-----------------gyFta--rDG-V--QL-PW--------F----E----Ygn----lkASH---TILFLN 40 
WP_075096290   1 MTapppappaagegcptplawaevVqafqelG-EvrE--HAfsrravtsR----Rl-----G------RGK---PIYFLN 59 
WP_058235459  42 GGPGSGLGtGkyrADFD-P--DRYFIVSFDQRGCGRSTp-hVtdprhrlT-D--N-TTPHL---IADIEALRSHLGvSSF 110
NP_601930     12 ESQQTPDEfT---EVVN-EipAGIKPRIVPW----------S-------G-S--V-SAGVQ---A--VESILDREEiRRV 61 
WP_014452187  37 GIFMHYESwK---ILSK-GipQNIPVLFHNFRCQWGSGc-aE-------D-K--EcSFERH---VEDLKELLDYLGiKKA 98 
WP_013317665  34 GALSTTAAfK---NTVK-NlsSRFNIILFDLPFIGESlp-hN-------TlDrvI-TKNDE---VNILLHLIDTL--EPd 95 
WP_014797983  30 GLSQSTVSwY---PIVQ-VlkNQFNIVLIDSIFQGQSDq-kG-------D-Y--R-SFEQH---AADANQVLEKINaKRI 90 
WP_024268931  29 GIGMSMNHwM---PFVD-AysQHAPFLLHDFRGQLFSEk-pR-------G-G--Y-SLQNH---ADDTVQLMDHLGiETA 89 
WP_012662985  30 GAGMNCHSwE---PQVA-GlsPHFNTLALNLPGRGTSLg--K-------A-N--A-SIEQN---VDFLVEFIDKNQiKMP 89 
WP_108603229  36 GNSKSALQfS---QQLQgEfaEQYRVIALDLPGHGLSGrldS-------S-A--Y-TIPSL---SNLLVEFSQALQlQEA 98 
WP_014804401  41 GFTCNQYNiA---KVVA-TlgVDYRIVTFDYRGQGLAYr--Er-----yK-K--V-SIDAV---LDDIDALHEHIGrIPV 102
WP_075096290  60 HASGDGLLfA---LTAW-LlkDEAECVVIDYP--AVR----S-------G-L--T-AAGFLpavVEGLEQVRSDLGhGSV 118
WP_058235459 111 LVAGVSWGSTLALAYAQAHPdrVAALILVAvtttsreevdwitegvgaifpemwdelaefaqehggfepedrspqrkrlv 190
NP_601930     62 ILVGAGTGAGVALEIAKNQPrrVERLVldsplvtfdekqlkgmst----------------------------------- 106
WP_014452187  99 KFIGTSYGGEVGMLFGATYPeyVEAMMIITstarvdkvmeskvlrwkdgaksrn-------------------------- 152
WP_013317665  96 HILSISWGGLSSMLALSNKPkrIKKAVIASfsahlndkmrdyiqrarhyih----------------------------- 146
WP_014797983  91 VPIGISYGGAVAMRLLVNYPtnIEKAVLLStfanrtpyfdfigntwrsallsggyelm--------------------ld 150
WP_024268931  90 DIIGTSYGSEVAMEFAIAYPrrTRSLVIIDgvseldpvltaaveswksaalsd--------------------------- 142
WP_012662985  90 IVCGISMGGAVVLSLLARNLdnIKSGIVINsgarlrvntmllksiqkny------------------------------- 138
WP_108603229  99 IFVGWSLGGNVVMHSIERLPq-AKGFVIVGavpfdkpmnmaclleapflsay---------------------------- 149
WP_014804401 103 LLFGYSMGCQLAVEWNYRDNtrVIGLVLLLgiygnifdsflntkifapmlnatyhafpflkpi---------lkrtwrta 173
WP_075096290 119 NVYGATLGGLCGLEWMRQRPgsVARGILqtpmfsvpwtpmertlfalgrrl----------------------------- 169
WP_058235459 191 sayadmltgsdlqlrdraaavwcvwEdeHir-igKAGvyerRTarqitapdatdsecgpevsadlIAF------CTLvth 263
NP_601930    107 ---------------------------------------------------------alkmmpgfffrkknkkdlLQqve 129
WP_014452187 153 -seifvnswltdvysegyinsinnlS--Qi------I----ASrltg---------------fnyEGAv-----RLLnvf 199
WP_013317665 147 -------skefehaaellnnevgkflppLlkhinLKH----ISsm------------------seFAF------QQVnfh 191
WP_014797983 151 vmlpavlgqdyffsplipiqdiqnaR--Lln-kiTS------Dsl----------------------------mkLMdat 193
WP_024268931 143 ---prvfyrslipwnysagylethlA--Qlr-erEEL----VAglpq---------------eyfQAFa-----SLCdaf 192
WP_012662985 139 ------trylstlgqfalspknnspE--LidalgPTM----VQdp----------------------------gTTLkdf 178
WP_108603229 150 ----fevdfpteeiekllaankvsaEsdk--qaiHQA----IKqs-------------------dAQVr-----STLaas 195
WP_014804401 174 hrlpfairlalgkgtllnpdrvneaElr----pfLDQ----LAel------------------dfEYIl-----HMShai 222
WP_075096290 170 --pgtlaglpgwkgmlernhrdwfpP--Fdptrwd-------------------------fllanQGAtplrdaAVRlra 220
WP_058235459 264 yws--hdgfgPe-gGlL---TRMdrlhGIPGTLIHGRRDVSGpAVTAWNLH-RAWPGSRLIIVEEEGHg--gPrM---ME 331
NP_601930    130 e------artAv-pMgF---SEI----TMPTLIIRGSAAKAGiDSDLEK----QIPSARATTIIGANWltytT-H---GR 187
WP_014452187 200 lr----lndlNl-lEkV---KNF----EFPVLIISAEEDNIKpKKFSEEIY-RQLKNALHLTIPNSGHavvvE-K---PK 262
WP_013317665 192 idqvltlkeeQy-iEiF---KDI----NAEILFLNGENDEYTtADDIKKME-KYIRlCEFSTIPEAGHfldlE-NrkaAK 261
WP_014797983 194 e------nsgDy-rEeL---KSV----SIQVKVIHGSQDILTtPKMGQNIV-DALPNASFKLLPRKGHtlnlE-A---IP 254
WP_024268931 193 -------aeiDl-tPrL---EMI----QCPSLVMVGENDILKhRGFARIIA-DNIAGSRLEIIPSAGHavviE-Q---PG 252
WP_012662985 179 ma----cnsfNl-mDdL---HRI----TRPVLILTASDDVLTpAKYGEHLE-STITDARRHSIADAGHlspmE-R---PD 241
WP_108603229 196 i-----fhepDyrhE-LaivKQM----QAPLTFIFGMEDNVFsIPFMRELVnETLTHTQLKLIPQAVHfphiS-H---AS 261
WP_014804401 223 -------hhhTn-eGqF---DRI----KAPCLIISGEADLFAlPQHSERVH-QAVAASWYFSIPAGTHnavlE-H---SE 282
WP_075096290 221 -------agtPl-sAeT---KSI----AQPVLIVRTEGEGAGlTRNAETLA-ATLPHATTEWMHTAGHspflT-H---PH 280
WP_058235459 332 HWRRATDAYADT 343
NP_601930    188 QTGAAIAEFLAQ 199
WP_014452187 263 EIGYLISTFVRN 274
WP_013317665 262 QVAERIITFFA- 272
WP_014797983 255 ELILEIENFLKV 266
WP_024268931 253 EVARRTHDFLKQ 264
WP_012662985 242 AVNQEIKRFINH 253
WP_108603229 262 AFNQCLAEIVEQ 273
WP_014804401 283 EITSWIAEFLRE 294
WP_075096290 281 RLVKLIRAHLLE 292
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