Conserved Protein Domain Family
DUF4201

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pfam13870: DUF4201 
Domain of unknown function (DUF4201)
This is a family of coiled-coil proteins from eukaryotes. The function is not known.
Statistics
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PSSM-Id: 464008
Aligned: 46 rows
Threshold Bit Score: 96.1349
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001954093 492 MLEMRNQISQKRYELNLNLHALAFVDEKVTRFERVTDTLTISQLLCANESIIQLSKLLEEKSKDVAVMQSNYKKSMIEET 571
Q5XJN6       164 IKAKDILIEKLHRKNSALLTHKKKQQAQLRQQEEMAEGVTVLDFELLKFENIRFRKQLDEQNLKQVNLKLLAVKTLQTLN 243 zebrafish
EEN50179     190 IRAKDTLIEKLRLKNSSLKVQKRKLQLQLKQKEEMGEVLHEVDFQQLKIENAQYLERIDERNQDLLRLKLMAGNTMQVLN 269
EDV25978     190 IRQRDTLVEKLRLKNAALRAQKRKLNLQLKQKEEMGEVLHEVDFNQLKIENNQYLEKIDERNQELLRLKLMAANTLQILN 269
XP_001628027 182 LRARDTLIEKLRLKNSTLKVQKRKLHMQLKQKEEMGEVLHEVDFNQLKIENQQYLEKIDEKNQDLLRLKLMSGNVQQILN 261
OCA36904     199 MRARDSLVDKLRLKNAALKVQKKKMKMQVKQKEEMGEVLHEVDFQQLKIENAQFLERIDERNQDLLQLKLTAGDTLLVLN 278
Q8C5T8       179 NRRRDNIKDKLCLKNVSLKVQRKKMLSQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNKELIQLKLASGNTLQVLN 258 house mouse
Q9H0I3       179 NRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLN 258 human
Q57UP0       244 HGAQGKYLDKLNAQCAAAERSILQHQRNLKQRRAAGEAFHAIDFEQLRIENQKFVERIERKNLELVELKGTSTRTVQTLN 323 Trypanosoma brucei
Q4DUJ8       240 YSMQAKYLDKLNVQCAAAERNITQTQQQLRQRHAAGEAFRAIDFEQLRIENQQFNERIERKNLELVELKGTSTRTVQTLN 319 Trypanosoma cruzi
XP_001954093 572 CIREKRDMISCSLSKAKKEYNDLIKRRTELRKLLTNLQAVHANLKLQRAQLEAKGGLLFKTALMYdYDKCMADVVSKRKR 651
Q5XJN6       244 SNKEKLHILTNESEMLSSDTALRTKLLVKIEEETEQAEEERHKAEALNRKLRDQLADFHVPHVLQ-YIKLKESHGQLQKS 322 zebrafish
EEN50179     270 SYKKKLNTLTAESERLKSEITSRQDMLTRIDAETNSVEEERSKAEKENKKYRTQLADYRVPDVLD-YVQDKADLYELQKT 348
EDV25978     270 SYRKKLHTLTLESNRLKTEIGQRHEILSKITVENDQVHHEKKMAESVNTNLKKQLADYKVPEIME-YVAERSNLYDLQKT 348
XP_001628027 262 TYKKKLHTLTMESERLRTEIGQRNELLFKIDAETNLVQTDREKAELLNEKLKQQLADYKVPDVMD-YVGERAKLYELNKV 340
OCA36904     279 LFKKKLNTAMAESTHLDKEIHMRKEMLQRIELEAQLVEQDREKAERVNKKLRKQLHDYRVPDVLE-YIQEKTDQEDLEKS 357
Q8C5T8       259 TYKNKLHRAMEIYVNLDKEILLRNELLGKIEKETIQAEEDRAKAHILNDKLRKQLAEFRAPQVMM-YVKEKILNGELEKT 337 house mouse
Q9H0I3       259 AYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMT-YVREKILNADLEKS 337 human
Q57UP0       324 NLMDTLNGLTSEQSRLRKDYKNRCEYLARLKREMVSVAQEAKVAEQKNTAIKLRHEAVRVPKIEN-YMAQKAEEYELRKA 402 Trypanosoma brucei
Q4DUJ8       320 TLMDALNGLTAEQNRLRKDLKNRCEYLARLQREMVSVTSEADAAERKNATIKSQHEAVRVPKIEH-YLAQKAEEYELQKA 398 Trypanosoma cruzi
XP_001954093 652 IVGLKKTISDFNKRIYV 668
Q5XJN6       323 VREWERKVEIAEMALKT 339 zebrafish
EEN50179     349 VKSWERKVEIAEMALKT 365
EDV25978     349 VKSWERKVEIAEMALKT 365
XP_001628027 341 VRMWERKVEIAEMALKT 357
OCA36904     358 IRIWERKVEIAELSMKT 374
Q8C5T8       338 IKMWERKVEIAEMSLKG 354 house mouse
Q9H0I3       338 IRMWERKVEIAEMSLKG 354 human
Q57UP0       403 QRNWQRKVEIAEGQLGL 419 Trypanosoma brucei
Q4DUJ8       399 ERHWNRKVEIAGGQMRL 415 Trypanosoma cruzi
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