6JAK_C 1 SRLVVVSNRIAPP-----------DEH-----AASAGg--LAVGILGALKA------AGG--LWFGWSGETGNEDQp--- 51 Escherichia coli O27785 15 KNPVIVSNRGPvef---------fkENdetvmKRGAGg--LVSTLLPLVER------FSG--VWISSAMTVEDARVasgy 75 Methanothermobacter... O14081 173 SRSLSFSMNGTPQrrmtf--daeaWKNvifkiKPSSFg--NASFYNAISAAtrskqfDDH--LFVGTCGIPTDSLPds-- 244 Schizosaccharomyces... P38426 286 PKFGGYSNNAKLRaslmr-nsyelFKHlpwtiVDSDKg--NGSLKNAVNIAvaektvKEPv-SWVGTMGIPTDELPhe-- 359 Saccharomyces cerev... P38427 317 PKFGGYSNKSKLKkyallrssqelFSRlpwsiVPSIKg--NGAMKNAINTAvleniiPHRhvKWVGTVGIPTDEIPen-- 392 Saccharomyces cerev... P78875 30 LKSLGVSGRIIYVlrhlpfkssinEETrewdlSGRRGattMYSSMNWLANS------TYWqtTLVGWTGVIPTVSEke-e 102 Schizosaccharomyces... O14145 78 GNDHTVETKIDEAavvhr-sssivISPedqeiFLKKAt--EYYRKKNIEAD------IVP--VWGKVQRVPQAKSS---- 142 Schizosaccharomyces... P31688 61 YEQHVVGWTGEITrtern--lftrEAKek-pqDLDDDp--LYLTKEQING--------LT-----TTLQDHMKSDKe--- 119 Saccharomyces cerev... Q0WUI9 57 ERKIIVANMLPLQskr-----daeTGKwcfnwDEDSL---QLQLRDGFSSE------TEF--LYVGSLNVDIETNE---- 116 thale cress O80738 59 ERKIIVANFLPLNgkk-----dseTGKwkfslDNDSP---LLHLKDGFSPE------TEV--IYVGSLKTHVDVSE---- 118 thale cress
6JAK_C 52 -LKKVK----------KGNIT----------WASFNLS------EQDLDEYYNQ------FSNAVLWPAFHYRLD----- 93 Escherichia coli O27785 76 pENRVPlp------edDPRFT----------VSFVIVD------RERYESYYSI------ISNPLLWFVQHYMWNtpydp 127 Methanothermobacter... O14081 245 lKERIShd-------yITEHS----------SLVVYPT------DTDFVGHYNH------YCKNILWPTFHYQIPdn--- 292 Schizosaccharomyces... P38426 360 vCHKISkk-------lEQDFS----------SFPVVTD------DITFKGAYKN------YAKQILWPTLHYQIPdn--- 407 Saccharomyces cerev... P38427 393 iLANISds-------lKDKYD----------SYPVLTD------DDTFKAAYKN------YCKQILWPTLHYQIPdn--- 440 Saccharomyces cerev... P78875 103 nKDAVTrldsqdvkrfEETYSqwnsgersteYVPVWLPgpekgsETIINETRSQqsrwlaYAENVIRPLIHYKYWps--- 179 Schizosaccharomyces... O14145 143 -SATITps-------vSNKLS------------TAYQS-------IKSEALKDGp----mYADSVLWDVLHYRIPt---- 187 Schizosaccharomyces... P31688 120 aKTDTTqt-------aPVTNN----------VHPVWLL-------RKNQSRWRN------YAEKVIWPTFHYILNps--- 166 Saccharomyces cerev... Q0WUI9 117 -QEEVSqk-------lLEEFN----------CVATFLS------QELQEMFYLG------FCKHQLWPLFHYMLPmfp-- 164 thale cress O80738 119 -QDEVShn-------lFEEFN----------CVATFLP------QDVHKKFYLG------FCKQQLWPLFHYMLPmcp-- 166 thale cress
6JAK_C 94 --LVQFQRPAWDGYLRVNALLADKLLPLLQ---DDDIIWIHDYHLLPFAHELRKRGVN--NRIGFFLHIPFPTPEIFNAL 166 Escherichia coli O27785 128 qiDDKVYRAWEDGYVHVNKKFGDKVISEIErneKDSLIMLQDYHLYLCPFFIKKEIGD--VFLSHFIHIPWPQRDYFNIL 205 Methanothermobacter... O14081 293 pkSKAYEDHSWANYVKVNKAFADTIVDNYE---QDDMIWINDYHLLLVPEMVRERLPR--AKIGFFLHIPFPSSEVFRCL 367 Schizosaccharomyces... P38426 408 pnSKAFEDHSWDYYQKVNQKFSDRIVSVYK---PGDTIWIHDYHLMLVPQMVREKLPK--AKIGFFLHVSFPSSEVFRCL 482 Saccharomyces cerev... P38427 441 pnSKAFEDHSWKFYRNLNQRFADAIVKIYK---KGDTIWIHDYHLMLVPQMVRDVLPF--AKIGFTLHVSFPSSEVFRCL 515 Saccharomyces cerev... P78875 180 seVDENEEQWWRDYVKMNHAFADKICEIYK---PGDFIIVQDYSLFLVPQLIRNKIDD--AVIGFYHHHPFPSSEIARCF 254 Schizosaccharomyces... O14145 188 -lDGYQQHNLWKNFTRWSQYFADNIVSNYR---PGDLILIHDYSLFLLPRLIRKQLSD--APIVFFLHAPFCTSEVFRCL 261 Schizosaccharomyces... P31688 167 -nEGEQEKNWWYDYVKFNEAYAQKIGEVYR---KGDIIWIHDYYLLLLPQLLRMKFNDesIIIGYFHHAPWPSNEYFRCL 242 Saccharomyces cerev... Q0WUI9 165 dhGDRFDRRLWQAYVSANKIFSDRVMEVINp--EDDYVWIQDYHLMVLPTFLRKRFNR--IKLGFFLHSPFPSSEIYRTL 240 thale cress O80738 167 dhGERFDRGLWQAYVSANKIFADKVMGVINl--EEDYIWIHDYHLMVLPTFLRRRFHR--VKLGFFLHSPFPSSEIYRTL 242 thale cress
6JAK_C 167 P--TYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTR-----VTTRSAKS---HTAWGKAFRTEVYPIGIEPKEIAKQA 236 Escherichia coli O27785 206 PerMRADIIGGLLSNTILGFHIERYCANFFECCEDLG------YEVDGDRGi--VRNGDEKTLVKSYPISVDPESMERTV 277 Methanothermobacter... O14081 368 A--TRQEILKGMLGANILGFQIPEFAYHFLQTCSRLVN-----IDIRKNGV---VSFENRQIDVIALPISIDPGFIDRCL 437 Schizosaccharomyces... P38426 483 A--NRERILEGIIGANFVGFQTKEYKRHFLQTCNRLLA-----ADVSNDe----VKYHCNIVSVMYAPIGIDYYHLTSQL 551 Saccharomyces cerev... P38427 516 A--QREKILEGLTGADFVGFQTREYARHFLQTSNRLLM-----ADVVHDEE---LKYNGRVVSVRFTPVGIDAFDLQSQL 585 Saccharomyces cerev... P78875 255 P--RRRAILRSVLGADFIGFEDYSYARHFISCCSRVLD-----LEIGHDw----VNLNGNKVTVRAITVGIDVPRIIRSS 323 Schizosaccharomyces... O14145 262 S--KRAEILKGVLASNVIAMQTDSYTRHFLSTCSNVLG-----LETTSTHi---DTSDGFRVVVFSSHVSIDVPRVYSRC 331 Schizosaccharomyces... P31688 243 P--RRKQILDGLVGANRICFQNESFSRHFVSSCKRLLDatakkSKNSSNSDqyqVSVYGGDVLVDSLPIGVNTTQILKDA 320 Saccharomyces cerev... Q0WUI9 241 P--VRDEILRGLLNCDLIGFHTFDYARHFLSCCSRMLG-----LDYESKRGhigLDYFGRTVYIKILPVGVHMGRLESVL 313 thale cress O80738 243 P--VREELLRGLLNCDLIGFHTFDYARHFLSCCCRMLG-----LEYESKRGhiaLDYLGRTVFLKILPIGIHMGRLESVL 315 thale cress
6JAK_C 237 A-GPLPPKLAQLKAEL-KNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQA-YQDIRHQL 313 Escherichia coli O27785 278 SsPTFMEKDEFVRKLKgN-MFLIYRTDRADLSKNIIRGFRAYELFLRDHPEFHGKVKFLATGKPTRQQIRE-YRNYSEEV 355 Methanothermobacter... O14081 438 AsPPVEHWAKVLQDRFrGK-HIILSHDKLDPIRGLRSKLISFERFLQKYPEYRENTILLQVAPESLQDSE-----HLPHI 511 Schizosaccharomyces... P38426 552 RnGSVLEWRQLIKERWrNK-KLIVCRDQFDRIRGLQKKMLAYERFLIENPEYIEKVVLIQICIGKSSDPE-----YERQI 625 Saccharomyces cerev... P38427 586 KdGSVMQWRQLIRERWqGK-KLIVCRDQFDRIRGIHKKLLAYEKFLVENPEYVEKSTLIQICIGSSKDVE-----LERQI 659 Saccharomyces cerev... P78875 324 GnVSVSEKLEELNKRYeN-MKVILGRDRLDELYGVPQKLRSFQRFLRTYPEWRKKVVLIQITISSAFKHP----KLLSSI 398 Schizosaccharomyces... O14145 332 NsKPVSLKIQQLKSLYpSDKKLIVGRDQLTKACGVTHKLRAFRELLIHFPKWRGHVVLIQITSLPVGNNYS--NEELKKT 409 Schizosaccharomyces... P31688 321 FtKDIDSKVLSIKQAYqNK-KIIIGRDRLDSVRGVVQKLRAFETFLAMYPEWRDQVVLIQVSSPTANRNSPqTIRLEQQV 399 Saccharomyces cerev... Q0WUI9 314 SlDSTAAKTKEIQEQFkGK-KLVLGIDDMDIFKGISLKLIAMEHLFETYWHLKGKVVLVQIVNPARSSGKD-VEEAKRET 391 thale cress O80738 316 NlPATAEKLKEIQEKY-RGKKIILGVDDMDIFKGLSLKILAFEHLLQQYPSMLGKIVLIQIVNPARGSGKD-VQEARKET 393 thale cress
6JAK_C 314 ENEAGRINGKYGQLG--WTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPa-------------- 377 Escherichia coli O27785 356 KDTVEEINEKYGTDE--WKPIEYIYR-ADYELVAAAFKNYDCLIVNPIADGMNIVPKEAAIINRE--------------- 417 Methanothermobacter... O14081 512 SDIVTRINSAYSNIAsrHVPVILLRQKLGYAQFLALMMISDALIDNSLREGISLTSHQFIYVQRK--------------- 576 Schizosaccharomyces... P38426 626 MVVVDRINSLSSNISi-SQPVVFLHQDLDFAQYLALNCEADVFLVDALREGMNLTCHEFIVSSFE--------------- 689 Saccharomyces cerev... P38427 660 MIVVDRINSLSTNISi-SQPVVFLHQDLDFSQYLALSSEADLFVVSSLREGMNLTCHEFIVCSED--------------- 723 Saccharomyces cerev... P78875 399 KKLVQAINQEFGTDD--YTPVHHVEEQLEPADYFALLTRADALFINSIREGVSNLALEYVVCQRD--------------- 461 Schizosaccharomyces... O14145 410 ENLVAQINSEFGSLD--YTPVIHFHQLLDPDEYYALLSVANIACVSSVRDSMNTMALEYVACQQK--------------- 472 Schizosaccharomyces... P31688 400 NELVNSINSEYGNLN--FSPVQHYYMRIPKDVYLSLLRVADLCLITSVRDGMNTTALEYVTVKSHmsn---------flc 468 Saccharomyces cerev... Q0WUI9 392 YETARRINERYGTSD--YKPIVLIDRLVPRSEKTAYYAAADCCLVNAVRDGMNLVPYKYIVCRQGtrsnka---vvdssp 466 thale cress O80738 394 YDTVKRINERYGSHD--YEPVVLIDRPVPRFEKSAYYALAECCIVNAVRDGMNLVPYKYTVCRQGtpsmnkslgvsddlp 471 thale cress
6JAK_C 378 NPGVLVLSQFAGAANELTsA-LIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQ 452 Escherichia coli O27785 418 -DGALILSERAGCYDELAeHvIGVNPFDIKETADAIYSAMKMSPGKRKKLSEGLKSRVLKRTIYHWINEQFDDFED 492 Methanothermobacter the... O14081 577 RHRPLILSEFVGSASILNdNaIIVNPWDYSKTAEAFRTALTMSEEECQKRNKAMCNLILRHDAASWAVTFQSLIKE 652 Schizosaccharomyces pom... P38426 690 KNAPLLLSEFTGSSSVLKeGaILINPWDINHVAQSIKRSLEMSPEEKRRRWKKLFKSVIEHDSDNWITKCFEYINN 765 Saccharomyces cerevisia... P38427 724 KNAPLLLSEFTGSASLLNdGaIIINPWDTKNFSQAILKGLEMPFDKRRPQWKKLMKDIINNDSTNWIKTSLQDIHI 799 Saccharomyces cerevisia... P78875 462 RYGMVLLSEFTATSAMLHdV-PLINPWDYNECAEIISNALSTPLERRKMIERESYKQVTTHTMQSWTSSLIRSLAN 536 Schizosaccharomyces pom... O14145 473 NKGSLILSEFSGTAELLLsA-YLVNPYDYSRFAETINYCLNMTEKERERRFSSLWKQATSQSSQQWIYKLINRAAY 547 Schizosaccharomyces pom... P31688 469 YGNPLILSEFSGSSNVLKdA-IVVNPWDSVAVAKSINMALKLDKEEKSNLESKLWKEVP--TIQDWTNKFLSSLKE 541 Saccharomyces cerevisia... Q0WUI9 467 RTSTLVVSEFIGCSPSLS-GaIRVNPWDVDAVAEAVNSALKMSETEKQLRHEKHYHYISTHDVGYWAKSFMQDLER 541 thale cress O80738 472 RTSTLVLSEFIGCSPSLS-GaIRVNPWDVDAVADSLYSAITMSDFEKQLRHKKHFHYISTHDVGYWARSFSQDLER 546 thale cress
Jiyao W et al.(2023). "The conserved domain database in 2023.",