Conserved Protein Domain Family
PTZ00327

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PTZ00327: PTZ00327 
eukaryotic translation initiation factor 2 gamma subunit; Provisional
Statistics
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PSSM-Id: 240362
Aligned: 29 rows
Threshold Bit Score: 743.747
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
146078560  16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51 
71402512   16 FVtneQNERGLATQDINAL-------------NLDKINAETFEVMSRQATVN---------------------------- 54 
71660069   16 FVtneQNERGLATQDINAL-------------NLDKINAETFEVMSRQATVN---------------------------- 54 
74025632   16 LSsdpTRDCGLAAQNLSAM-------------DLDKMSVETFEVMSRQATIN---------------------------- 54 
154332930  16 VI---DTDQGLAKQDLSKI-------------NLDELNVDTFEVMSRQATIN---------------------------- 51 
146078555  16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51 
159114961   1 -----------MADSLGTLpltpmylsqqpflKPEELHPTHPDVISRQATIN---------------------------- 41 
118372425   1 --memTSNQQLNAQQIEELmnrnpqlrkqtyeQITNLSPLSPEVISRQATINigkqflsiqarfnyefinlgqklninml 78 
154332932  16 VI---DTDQGLAKQDLSKI-------------NLDELNVDTFEVMSRQATIN---------------------------- 51 
157865148  16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51 
146078560  52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127
71402512   55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFKCDKCELPAAFHAFPSSQPDKTDC--PTCGSP 130
71660069   55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFKCDKCELPAAFHAFPSSQPDKTDC--PTCGSP 130
74025632   55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFRCDSCPVPAAYHAFPSSQPDKTGC--PTCGAP 130
154332930  52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQAYPSSQPDSTPC--PNCGKT 127
146078555  52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127
159114961  42 --IGTIGHVAHGKSTLVKAITGITTGRFHSEMERNITIKLGYANAKIFKCPKCPEPHNYFPTSSSMPDNSKC--KMCGSV 117
118372425  79 nkIGTIGHVAHGKSTLVKAISGVHTVKFKQEKVRNITIRLGYANAKIYQCPSCPAPQCYKSYSSDKTDDAKCdnEGCNQT 158
154332932  52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQAYPSSQPDSTPC--PNCGKT 127
157865148  52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127
146078560 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVS---SLIVLQNKVDLV--S-K 201
71402512  131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMRLA---NLVILQNKIDLV--G-E 204
71660069  131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMRLA---NLVILQNKIDLV--G-E 204
74025632  131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMKLR---NLIILQNKIDLV--G-E 204
154332930 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLKAVEIMKLR---HLVVLQNKIDLV--G-E 201
146078555 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLKAVEIMKLR---HLVVLQNKIDLV--G-E 201
159114961 118 GTLVRHISFVDCPGHDFYMATMLTGACVMDAALLLIAADQPCPQSQTKEHLAAIDIAGITkadRVIIVQNKIDLI--K-E 194
118372425 159 MTLIRHVSFVDCPGHDILMSTMLTGAAVMDAALLIVAGNMTCPQPQTAEHLAAVDIMKLK---HILIIQNKIDIIfkEsK 235
154332932 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVS---SLIVLQNKIDLV--S-K 201
157865148 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVL---SLIVLQNKVDLV--S-K 201
146078560 202 ERAAAQHSIIHHYLATKTAyAKAPVIPICAQQHVNISFLLDYLV-HIPLPRRQLHHAQYMNVLRSFDVSLPGPagdGAKA 280
71402512  205 VHAQDQYHKIRNYIDSTIG-SNIPIIPISAQLKRNIDYLLEYLC-HIPLPTRQLNCPAHMTVVRSFDINKPGEv--DIEN 280
71660069  205 VHAQDQYHKIRNYIDSTIG-SNIPIIPISAQLKRNIDYLLEYLC-HIPLPTRQLNCPAHMTVVRSFDINKPGEv--DIEN 280
74025632  205 VHAQDQYHKIRDYIDSTIG-LSAPIIPISAQLKRNVDYLLEYLC-RMPLPTRQLNCPARMTVVRSFDINKPGEv--DIET 280
154332930 202 VKAHDQYRQVRAYLDN-IA-LNVPIVPISAQLKRNVDYLLEYLL-HIPMPVRQLKAPVRMTVVRSFDINKPGEg--DIER 276
146078555 202 VKAHDQYRHVRAYLDN-IA-LNVPIVPISAQLKRNVDYLLEYLL-HIPMPVRQLKAPVRMTVVRSFDINKPGEg--DIES 276
159114961 195 QEAKSHHQQIVNYLNISLKtKNPHIIPTSAVSGYNVDLVLHHIVnKLPIPKRDLTLPPLFMVIRSFDVNKPGY---DIDN 271
118372425 236 DAAVQNYKEIKQFILGTNA-ENSPIIPCSAQLKYNVDAVCQYICtYFPVPQRDLKANPKLIIIRSFDVNKPGA---TVDT 311
154332932 202 AHAAAQYNVIHHYLTTKTAyAKAPVVPICAQKQINVSFLLDYLV-HIPLPRRQLRHTQYLNVLRSFDVSLPGPaghNAMA 280
157865148 202 ERAAAQYSIIHHYLATKTAyAKAPVIPICAQQHANISFLLDYLV-HIPLPRRQLHHAQYMNVLRSFDVSLPGPagdGAKA 280
146078560 281 LKGGVVGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprradvlsgrelayvasppPGELYAVPLRTTVVRLQAEKNELQ 360
71402512  281 LRGGVAGGTVTRGIIRVNQVLEIRPGQVHAQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336
71660069  281 LRGGVAGGTVTRGIIRVNQVLEIRPGQVHAQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336
74025632  281 LRGGVAGGTVIQGVLRVNQIVEIRPGQVHTQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336
154332930 277 LKGGVAGGTVTQGVIKVGQVVEIRPGLVRSRStn--------------------eqGGRFTYSPLKTRTVTLKAENNVLQ 336
146078555 277 LKGGVAGGTVTQGVIKVGQVVEIRPGLVRSRSsn--------------------eqGGRFTYSPLKTRTVTLKAENNVLQ 336
159114961 272 IRGGVAGGTLLQGMFKLGDTVEIRPGYTIMNEk-----------------------TGKCSCYPLITKIISIKADENELR 328
118372425 312 LKGGVVGGSILEGILKIGDEIEIRPGLISKDQ------------------------NGNVKCTPIKSRIVSLLAEKNDLL 367
154332932 281 LQGGVVGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprrsdvlsgqeaayvasppPGELYAVPLRTTVVRLQAEKNELQ 360
157865148 281 LKGGVIGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprradvlsgrelayvasppPGELYAVPLRTTVVRLQAEKNELQ 360
146078560 361 FAVPGGLIAIGTTLDPSLTRQNKLRGQVVRVVSRGPvwrsrgtrcslrrcdsppavaeaasasttpatt--ttgdatptp 438
71402512  337 YAVPGGLIAVGTTLDPTLTRQDKMVGHMIADEGSLP-------------------------------------------- 372
71660069  337 YAVPGGLIAVGTTLDPTLTRQDKMVGHMIADEGSLP-------------------------------------------- 372
74025632  337 YAIPGGLIAVGTTLDPTLTRQDKMVGHMIGEEGSLP-------------------------------------------- 372
154332930 337 YAIPGGLIAVGTTLDPTLTRQDKMVGNMLGEEGTLP-------------------------------------------- 372
146078555 337 YAIPGGLIAVGTTLDPTLTRQDKMVGNMLGEEGTLP-------------------------------------------- 372
159114961 329 YAIPGGLIAIGTFIDPSYTRQDRLVGSVIGYPGHMP-------------------------------------------- 364
118372425 368 YAVPGGLIGVGLLVDPSITRNDRLVGNVLGYPGKLP-------------------------------------------- 403
154332932 361 FAVPGGLIAIGTTLDPSLTRQNKLRGQVVRVVRRGPvwrsghmehsprscdsppavagagassasatlattitsnatatp 440
157865148 361 FAVPGGLIAIGTTLDPSLTRQNKLRGHVVRVVSRGPvwrsrrmgcrprrcdsppavaeaasasttpvtt--ttsdatwtp 438
146078560 439 sgavlpcqspapapvavechtgmQVYQEVVIQFFLLREILGLAAPRPGRAkphrdrdrdfnggadsyrvhpdrvvsslhR 518
71402512  373 -----------------------EVYAEIEVQYFLFEEMVGRSKQRDRNA-----------------------------K 400
71660069  373 -----------------------EVYAEIEVQYFLFEEMVGRSKQRDRNA-----------------------------K 400
74025632  373 -----------------------QVYAEIEVQYYLFSEMVGQSKQRDRNA-----------------------------K 400
154332930 373 -----------------------EVYCEIEVQYYLFSEMVGAKSKDGKSTa----------------------------K 401
146078555 373 -----------------------EVYCEIEVQYYLFSEMVGAKSKDGKSTa----------------------------K 401
159114961 365 -----------------------PIRLNITIYYELMHQLISAVNTNN--------------------------------T 389
118372425 404 -----------------------EIYTKISVNFYLLKRLIGVKSEGDNRS-----------------------------H 431
154332932 441 lssaspcplpapaaamrecrpgiQVYQEVLIQFFLLREILGLAAQRPSNAtphrgdgagvnggp-gsyrvhpdrvtsvhR 519
157865148 439 sgavlpcpspapaaaavechtgmQVYQEVVIQFFLLREIIGLAAPRPGRTtshrdkdrgfnggansyrvhpdrvvsslhR 518
146078560 519 RVVPLREDESIILSVGTLTTAATVLRTSRHagRAICR---LESPLSADpPHQRIVLARYV----DRKVRVIGWGTILKGV 591
71402512  401 RVQKLNLQETLQINVGTLTAGATVVNITKNpdIAKLT---LVTPVCCT-LDEHIAISRLV----EKNFRLIGWGIIRRGV 472
71660069  401 RVQKLNLQETLQINVGTLTAGATVVNITKNpdIAKLT---LVTPVCCT-LDEHIAISRLV----EKNFRLIGWGIIRRGV 472
74025632  401 RVQKLNVQETLQINVGTLTAGATVVSITKSpdIAKLT---LVTPVCCT-MDEQIAISRLV----EKNFRLIGWGTIRRGV 472
154332930 402 RVQKLNVLESLQINVGTLTAGSTVLNITQDpeIAKLE---LVTPVCCS-TGEQVAISRMV----DKTFRLIGWGTIRRGV 473
146078555 402 RVQKLNVLESLQINVGTLTAGATVLNITQDpeIAKLE---LVTPVCCS-TGEQVAISRMV----DKTFRLIGWGTIRRGV 473
159114961 390 KIAVLAVNEVILFTIGSNSVSGTIKAVRTVngVEKIAdvvMNKPICAK-TGEQIAISRKIatgaSRSWRLIGWGKIQDNP 468
118372425 432 KIAKITALETLKFNVGSTETPGRVVQVQDN--VMTVE---LNNPLCTQ-IGEKVAFSRRI----DKKFRLIGWGVIKSGQ 501
154332932 520 RVAPLREGESIILSVGTLTTAATVLRTSRHagRAICR---LENPLSADpPQQRIVLARYV----DRKVRVIGWGTIRKGV 592
157865148 519 RVAPLREEESIILSVGTLTTAATVLRTSQHagRAICR---LESPLSADpPHQRIVLARYV----DRKVRVIGWGTILKGV 591
146078560 592 PVKLLPE 598
71402512  473 PVKLN-- 477
71660069  473 PVKLN-- 477
74025632  473 PVKLN-- 477
154332930 474 PMKQSS- 479
146078555 474 PMKQSS- 479
159114961 469 DWENLNS 475
118372425 502 TMGVQN- 507
154332932 593 PVKLLPE 599
157865148 592 PVKFLPE 598
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