146078560 16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51 71402512 16 FVtneQNERGLATQDINAL-------------NLDKINAETFEVMSRQATVN---------------------------- 54 71660069 16 FVtneQNERGLATQDINAL-------------NLDKINAETFEVMSRQATVN---------------------------- 54 74025632 16 LSsdpTRDCGLAAQNLSAM-------------DLDKMSVETFEVMSRQATIN---------------------------- 54 154332930 16 VI---DTDQGLAKQDLSKI-------------NLDELNVDTFEVMSRQATIN---------------------------- 51 146078555 16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51 159114961 1 -----------MADSLGTLpltpmylsqqpflKPEELHPTHPDVISRQATIN---------------------------- 41 118372425 1 --memTSNQQLNAQQIEELmnrnpqlrkqtyeQITNLSPLSPEVISRQATINigkqflsiqarfnyefinlgqklninml 78 154332932 16 VI---DTDQGLAKQDLSKI-------------NLDELNVDTFEVMSRQATIN---------------------------- 51 157865148 16 VI---DTDQGLAKQDFSKI-------------DLDELNVDTFEVMSRQATIN---------------------------- 51
146078560 52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127 71402512 55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFKCDKCELPAAFHAFPSSQPDKTDC--PTCGSP 130 71660069 55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFKCDKCELPAAFHAFPSSQPDKTDC--PTCGSP 130 74025632 55 --IGTIGHVAHGKSTVVKALSGVKTQKYHREAVMNITIHLGYANAKVFRCDSCPVPAAYHAFPSSQPDKTGC--PTCGAP 130 154332930 52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQAYPSSQPDSTPC--PNCGKT 127 146078555 52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127 159114961 42 --IGTIGHVAHGKSTLVKAITGITTGRFHSEMERNITIKLGYANAKIFKCPKCPEPHNYFPTSSSMPDNSKC--KMCGSV 117 118372425 79 nkIGTIGHVAHGKSTLVKAISGVHTVKFKQEKVRNITIRLGYANAKIYQCPSCPAPQCYKSYSSDKTDDAKCdnEGCNQT 158 154332932 52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQAYPSSQPDSTPC--PNCGKT 127 157865148 52 --VGTIGHVAHGKSTVVKALSGVKTQKFHREAVMNITIHLGYANAKVYQCETCPRPTCYQTYPSSQPDSTPC--PNCGET 127
146078560 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVS---SLIVLQNKVDLV--S-K 201 71402512 131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMRLA---NLVILQNKIDLV--G-E 204 71660069 131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMRLA---NLVILQNKIDLV--G-E 204 74025632 131 LTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANEPFPQPQTLEHLKAVEIMKLR---NLIILQNKIDLV--G-E 204 154332930 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLKAVEIMKLR---HLVVLQNKIDLV--G-E 201 146078555 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLKAVEIMKLR---HLVVLQNKIDLV--G-E 201 159114961 118 GTLVRHISFVDCPGHDFYMATMLTGACVMDAALLLIAADQPCPQSQTKEHLAAIDIAGITkadRVIIVQNKIDLI--K-E 194 118372425 159 MTLIRHVSFVDCPGHDILMSTMLTGAAVMDAALLIVAGNMTCPQPQTAEHLAAVDIMKLK---HILIIQNKIDIIfkEsK 235 154332932 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVS---SLIVLQNKIDLV--S-K 201 157865148 128 MTLKRHFSFVDCPGHDVLMATMLNGAAIMDAALLLIAANESFPQPQTLEHLAAAEMIGVL---SLIVLQNKVDLV--S-K 201
146078560 202 ERAAAQHSIIHHYLATKTAyAKAPVIPICAQQHVNISFLLDYLV-HIPLPRRQLHHAQYMNVLRSFDVSLPGPagdGAKA 280 71402512 205 VHAQDQYHKIRNYIDSTIG-SNIPIIPISAQLKRNIDYLLEYLC-HIPLPTRQLNCPAHMTVVRSFDINKPGEv--DIEN 280 71660069 205 VHAQDQYHKIRNYIDSTIG-SNIPIIPISAQLKRNIDYLLEYLC-HIPLPTRQLNCPAHMTVVRSFDINKPGEv--DIEN 280 74025632 205 VHAQDQYHKIRDYIDSTIG-LSAPIIPISAQLKRNVDYLLEYLC-RMPLPTRQLNCPARMTVVRSFDINKPGEv--DIET 280 154332930 202 VKAHDQYRQVRAYLDN-IA-LNVPIVPISAQLKRNVDYLLEYLL-HIPMPVRQLKAPVRMTVVRSFDINKPGEg--DIER 276 146078555 202 VKAHDQYRHVRAYLDN-IA-LNVPIVPISAQLKRNVDYLLEYLL-HIPMPVRQLKAPVRMTVVRSFDINKPGEg--DIES 276 159114961 195 QEAKSHHQQIVNYLNISLKtKNPHIIPTSAVSGYNVDLVLHHIVnKLPIPKRDLTLPPLFMVIRSFDVNKPGY---DIDN 271 118372425 236 DAAVQNYKEIKQFILGTNA-ENSPIIPCSAQLKYNVDAVCQYICtYFPVPQRDLKANPKLIIIRSFDVNKPGA---TVDT 311 154332932 202 AHAAAQYNVIHHYLTTKTAyAKAPVVPICAQKQINVSFLLDYLV-HIPLPRRQLRHTQYLNVLRSFDVSLPGPaghNAMA 280 157865148 202 ERAAAQYSIIHHYLATKTAyAKAPVIPICAQQHANISFLLDYLV-HIPLPRRQLHHAQYMNVLRSFDVSLPGPagdGAKA 280
146078560 281 LKGGVVGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprradvlsgrelayvasppPGELYAVPLRTTVVRLQAEKNELQ 360 71402512 281 LRGGVAGGTVTRGIIRVNQVLEIRPGQVHAQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336 71660069 281 LRGGVAGGTVTRGIIRVNQVLEIRPGQVHAQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336 74025632 281 LRGGVAGGTVIQGVLRVNQIVEIRPGQVHTQT------------------------GGTFSCTPLRTRALTLKAEDNSLQ 336 154332930 277 LKGGVAGGTVTQGVIKVGQVVEIRPGLVRSRStn--------------------eqGGRFTYSPLKTRTVTLKAENNVLQ 336 146078555 277 LKGGVAGGTVTQGVIKVGQVVEIRPGLVRSRSsn--------------------eqGGRFTYSPLKTRTVTLKAENNVLQ 336 159114961 272 IRGGVAGGTLLQGMFKLGDTVEIRPGYTIMNEk-----------------------TGKCSCYPLITKIISIKADENELR 328 118372425 312 LKGGVVGGSILEGILKIGDEIEIRPGLISKDQ------------------------NGNVKCTPIKSRIVSLLAEKNDLL 367 154332932 281 LQGGVVGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprrsdvlsgqeaayvasppPGELYAVPLRTTVVRLQAEKNELQ 360 157865148 281 LKGGVIGGTVAAGVLCVGDEIEIIPGLLVLRRrdgvlprradvlsgrelayvasppPGELYAVPLRTTVVRLQAEKNELQ 360
146078560 361 FAVPGGLIAIGTTLDPSLTRQNKLRGQVVRVVSRGPvwrsrgtrcslrrcdsppavaeaasasttpatt--ttgdatptp 438 71402512 337 YAVPGGLIAVGTTLDPTLTRQDKMVGHMIADEGSLP-------------------------------------------- 372 71660069 337 YAVPGGLIAVGTTLDPTLTRQDKMVGHMIADEGSLP-------------------------------------------- 372 74025632 337 YAIPGGLIAVGTTLDPTLTRQDKMVGHMIGEEGSLP-------------------------------------------- 372 154332930 337 YAIPGGLIAVGTTLDPTLTRQDKMVGNMLGEEGTLP-------------------------------------------- 372 146078555 337 YAIPGGLIAVGTTLDPTLTRQDKMVGNMLGEEGTLP-------------------------------------------- 372 159114961 329 YAIPGGLIAIGTFIDPSYTRQDRLVGSVIGYPGHMP-------------------------------------------- 364 118372425 368 YAVPGGLIGVGLLVDPSITRNDRLVGNVLGYPGKLP-------------------------------------------- 403 154332932 361 FAVPGGLIAIGTTLDPSLTRQNKLRGQVVRVVRRGPvwrsghmehsprscdsppavagagassasatlattitsnatatp 440 157865148 361 FAVPGGLIAIGTTLDPSLTRQNKLRGHVVRVVSRGPvwrsrrmgcrprrcdsppavaeaasasttpvtt--ttsdatwtp 438
146078560 439 sgavlpcqspapapvavechtgmQVYQEVVIQFFLLREILGLAAPRPGRAkphrdrdrdfnggadsyrvhpdrvvsslhR 518 71402512 373 -----------------------EVYAEIEVQYFLFEEMVGRSKQRDRNA-----------------------------K 400 71660069 373 -----------------------EVYAEIEVQYFLFEEMVGRSKQRDRNA-----------------------------K 400 74025632 373 -----------------------QVYAEIEVQYYLFSEMVGQSKQRDRNA-----------------------------K 400 154332930 373 -----------------------EVYCEIEVQYYLFSEMVGAKSKDGKSTa----------------------------K 401 146078555 373 -----------------------EVYCEIEVQYYLFSEMVGAKSKDGKSTa----------------------------K 401 159114961 365 -----------------------PIRLNITIYYELMHQLISAVNTNN--------------------------------T 389 118372425 404 -----------------------EIYTKISVNFYLLKRLIGVKSEGDNRS-----------------------------H 431 154332932 441 lssaspcplpapaaamrecrpgiQVYQEVLIQFFLLREILGLAAQRPSNAtphrgdgagvnggp-gsyrvhpdrvtsvhR 519 157865148 439 sgavlpcpspapaaaavechtgmQVYQEVVIQFFLLREIIGLAAPRPGRTtshrdkdrgfnggansyrvhpdrvvsslhR 518
146078560 519 RVVPLREDESIILSVGTLTTAATVLRTSRHagRAICR---LESPLSADpPHQRIVLARYV----DRKVRVIGWGTILKGV 591 71402512 401 RVQKLNLQETLQINVGTLTAGATVVNITKNpdIAKLT---LVTPVCCT-LDEHIAISRLV----EKNFRLIGWGIIRRGV 472 71660069 401 RVQKLNLQETLQINVGTLTAGATVVNITKNpdIAKLT---LVTPVCCT-LDEHIAISRLV----EKNFRLIGWGIIRRGV 472 74025632 401 RVQKLNVQETLQINVGTLTAGATVVSITKSpdIAKLT---LVTPVCCT-MDEQIAISRLV----EKNFRLIGWGTIRRGV 472 154332930 402 RVQKLNVLESLQINVGTLTAGSTVLNITQDpeIAKLE---LVTPVCCS-TGEQVAISRMV----DKTFRLIGWGTIRRGV 473 146078555 402 RVQKLNVLESLQINVGTLTAGATVLNITQDpeIAKLE---LVTPVCCS-TGEQVAISRMV----DKTFRLIGWGTIRRGV 473 159114961 390 KIAVLAVNEVILFTIGSNSVSGTIKAVRTVngVEKIAdvvMNKPICAK-TGEQIAISRKIatgaSRSWRLIGWGKIQDNP 468 118372425 432 KIAKITALETLKFNVGSTETPGRVVQVQDN--VMTVE---LNNPLCTQ-IGEKVAFSRRI----DKKFRLIGWGVIKSGQ 501 154332932 520 RVAPLREGESIILSVGTLTTAATVLRTSRHagRAICR---LENPLSADpPQQRIVLARYV----DRKVRVIGWGTIRKGV 592 157865148 519 RVAPLREEESIILSVGTLTTAATVLRTSQHagRAICR---LESPLSADpPHQRIVLARYV----DRKVRVIGWGTILKGV 591
146078560 592 PVKLLPE 598 71402512 473 PVKLN-- 477 71660069 473 PVKLN-- 477 74025632 473 PVKLN-- 477 154332930 474 PMKQSS- 479 146078555 474 PMKQSS- 479 159114961 469 DWENLNS 475 118372425 502 TMGVQN- 507 154332932 593 PVKLLPE 599 157865148 592 PVKFLPE 598